김치유래 젖산균의 균체지방산 분석을 이용한 분류학적 연구

이정숙,정민철,김우식,이근철,김홍중,박찬선,이헌주,주윤정,이근종,안종석,박완,박용하,민태익 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.2

표준균주를 포함한 230여개의 김치유래 젖산균에 대한 균체지방산(FAMEs)을 분석하였다. FAMEs profiles는 Euclidian Distance 17.5에 의해 7개의 Major Cluster와 1개의 Single Cluster로 나뉘어졌다. 이중 A, B, C 및 Cluster는 Leuconostoc속으로 분석되어졌고, F는 Lactobacillus속으로 분석되어졌다. 그리고 E와 G cluster는 두개의 Genus가 혼재되어 나타났으며 보충적인 연구가 필요하다. 앞으로 김치유래 젖산균의 균체지방산 분석결과를 기반으로 한 데이타베이스에 95가지 탄소원을 이용하는 수치분류학적 접근방법 및 Pyrolysis Mass Spectrometry 등의 화학적 분석 방법과 분자친화적 연구를 통한 종합적 분류정보 체계가 갖추어지면 젖산균의 신속, 정확한 동정 및 연구에 활발히 이용되어질 것이다. Two hundreds and thirty lactic acid bacteria, mostly isolated from Kimchi, including type strains were sued for analysis of cellular fatty acids. The 230 test strains were recoverd in 7 major and 1 single clusters defined a Euclidian distance of 17.5. These aggregate taxa were equivalent to the genus Leuconostoc (aggregate group A, B, C and D), and the genera Leuconostoc and Lactobacillus (aggregate group G). It is concluded as evident that FAMEs (Fatty Acid Methyl Esters) profile of cell can be used as a criterion in classification of lactic acid bacterial from kimchi. Additional comparative taxonomic studies need to be carried out on well chosen representative strains to determine the most appropriate methods of value.

뇌졸중 후 중추성 통증 환자에 대한 동서협진이 진통과 재활에 미치는 영향

이현종,김수영,이상훈,서동민,이두익,김건식,이재동,이윤호,양형인,박재경,최도영 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 2003 東西醫學硏究所 論文集 Vol.2003 No.-

Purpose : In order to study the effectiveness of East-West pain treatment on central poststroke pain(CPSP), we evaluated its effect on alleviation of pain and rehabilitation of CPSP Patients who were treated with electroacupuncture and west pain treatment for four weeks. Methods : Twenty four patients diagnosed by their pain characteristics of central pain from stroke were treated with sympathetic nerve block, gabapentin, amitriptyline, and electroacupuncture for four weeks. Pain intensity through the visual analogue scale(VAS), and improvements of mobility and rehabilitation through the modified Barthel index(MBI) and Rankin scale(RS), respectively, before and after pain treatment were also assessed. Results : VAS pain scores were significantly improved from 7.7±1.7 to 4.4±2.0 with pain treatment(p<0.05). In accordance with improvement of pain scores, RS and MBI scores were also improved from 2.88±0.95 to 2.13± 1.01 and from 83.0± 16.9 to 94.7±9.5(p<0.05), respectively, with pain treatment(p<0.05). Conclusions : It was suggested that the active pain treatment was contributed to the rehabilitation of CPSP patients, resulting in improvement of quality of life of CPSP patients. Futhermore, East pain treatment in combination with West pain treatment may be useful modality to alleviate CPSP.

除草劑處理에 의한 簡易草地造成에 관한 硏究

李根常,尹益錫 건국대학교 1978 論文集 Vol.7 No.1

This study was conducted to investigate the effects of several herbicides under oversowing and the application methods of Gramoxone as well as effects of burning. These trials were established in 1974 on natural grassland in Che Ju where Miscanthus purpurascens and Imperata cylindrica are dominant and foil type is volcano ash. The results obtained from 3 years experimentation are summarized as follows. 1.Gramoxone, of immediate effect, and Round-up, of slow effect showed similiar effect of weed control and both herbicides did not affect on emergence and early growth of sown species. 2.In case of oversowing, herbicides application did not increase the total dry matter yield but the yield of sown species was increased significantly (P < 0.01). There were, however, no significant differences in grasses yield among different herbicides. 3.In the natural grassland where Miscanthus purpruascens and Imperata cylindrica were dominant, the optimal amounts of herbicides were 400cc in Gramoxone and 600cc in Round-up per 10 a when oversowing method was applied. 4.The times of herbicide application and burning of grassland before sowing did not affect on total dry matter yields, but burning helped emergence and establishment of the sown species compared to no burning. 5.When a pasture was established by oversowing the clover content was higher with herbicide application and increased with increasing rate of herbicides.

創作 시나리오를 이용한 討議式 學習活動이 中學生의 힘과 運動의 槪念 變化에 미치는 影響

윤은정,육근철,이춘우 공주대학교 사범대학 과학교육연구소 1996 과학교육연구 Vol.27 No.1

많은 중학생들은 기본적인 물리 개념에 대해서 오개념을 가지고 있으며 물리 교과를 매우 어렵게 생각하고 있기 때문에 물리교과에 대해서 흥미를 잃고있다. 그래서 본 연구에서는 힘과 운동에 대해 학생들이 가지고 있는 사전 개념을 조사한 후 전통적인 방법으로 수업을 받은 통제반과 교사의 역할이 없이 창작 시나리오를 가지고 토의활동을 한 실험Ⅰ반과 교사가 적절히 역할을 하면서 창작 시나리오를 가지고 토의활동을 한 실험Ⅱ반의 힘과 운동에 대한 개념변화를 조사·비교하여 토의학습의 가능성을 제안하였다. Many middle school students usually have some misconcepts and prejudices against the basic physical concepts. They have much trouble in understanding the several physical concepts in their class, especially on force and motion. Accordingly, Many students are losing interest in their physics class. Therefore, We studied on the change of the concepts about the force and motion through the learning discussion by comparision to the traditional method in this study. This study also intended to find out the effectivness of discussion method(Group Ⅰ: students-students, Group Ⅱ : students-teacher-students) after presentation of the creative scenario

대장에 발생한 샘암종에서 MUC1과 MUC2 점소 발현의 의의

이윤경,이주호,이용,심재영,박정훈,오수섭,박진실,기근홍 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

Background : Mucins possess the unique function of protecting and lubricating the epithelial surface and other important functions such as call growth, direct implication in the fetal development, the epithelial renewal and differentiation, the epithelial integrity, carcinogenesis, immune regulation, cellular adhesion and metastasis. Purpose : This study was done to provide the significance of alteration of MUC1 and MUC2 expression in colorectal adenocarcinoma, A series of 131 colorectal adenocarcinomas including 11 mucinous carcinomas were screened immunohistochemically for their expression of MUCI and MUC2, Materials and mehtods : Of 131 carcinomas, 76 (58,5%) were MUCI positive and 91 (68, 9%) were MUC2 positive, In normal colonic goblet cells, MUCl was not expressed but MUC2 was expressed in cytoplasm, Conclusion There were up-regulation of MUCI and down-regulation of MUC2 in colorectal carcinomas, The frequency of MUC2 positivity according to differentiation was statistically reliable. (p=0.0001)

전신적인 피부병변으로 발현한 모세포성 NK세포 림프종 1예

이근욱,윤탁,김동완,김태유,허대석,박영주,김노경 대한내과학회 2004 대한내과학회지 Vol.66 No.4

저자들은 다른 장기의 침범 없이 전신적인 피부 병변만으로 발현한 모세포성 NK세포 림프종 1예를 국내에서 처음으로 경험하였기에 이를 문헌고찰과 함께 보고하는 바이다. Reports of blastic natural killer (NK)-cell lymphoma are rare. In previous reports, primary cutaneous blastic NK-cell lymphomas were even rarer. In asian patients, most CD56+ lymphomas are classified as nasal type extranodal NK/T-cell lymphoma and mostly associated with the presence of Epstein-Barr virus (EBV) and have an aggressive clinical course. Few cases of blastic NK-cell lymphoma were reported previously in Korea but there was report about blastic NK-cell lymphoma initially presented as disseminated skin lesions without any other organ involvement. We report such a young patient who was treated by systemic chemotherapy.

한국어 불규칙 용언처리를 위한 연구

윤근수,이교운,박용욱 울산과학대학 1999 연구논문집 Vol.26 No.1

한국어 정보처리를 하기 위해서는 가장 기초기술인 형태소 분석이 이루어져야 한다. 한국어의 용언은 어미의 활용으로 인하여 형태소분석을 상당히 까다롭게 하는 특성을 가지고 있으며, 대부분의 어절을 대상으로 용언의 불규칙 현상이 있는 지를 조사해야 하므로 시스템의 속도를 떨어뜨리게 된다. 따라서 이 논문에서는 용언 불규칙현상을 분류하고 알기 쉽도록 도식화하면, 전체 시스템의 속도를 높이기 위한 새로운 자료구조 도입과 알고리즘을 소개한다. Korean Morphological analysis is basic technic of Korean Information processing. Korean morphological analyzer is complicated because of irregular verbs. In this paper, we suggest analysis, diagram, and algorithm of korean irregular verbs processing. The system becomes very efficient because the number of dictionary accesses is minimized. The system makes easy to analyze unknown words like compound nouns without adding them to the dictionary.

누적외상성질환 위험 요인의 정량적 평가 및 관리를 위한 점검표 개발 : 자동차 조립 작업을 중심으로

이윤근,김현욱,임상혁,박희석 한국산업위생학회 2001 한국산업보건학회지 Vol.11 No.1

Objectives : This study was designed to develop and standardize a checklist for ergonomic risk factors, and to provide ergonomic guidelines for managing cumulative trauma disorders (CTDs) in automobile assembly lines, Methods : The Checklist for Ergonomic Risk Factors(CERF-1) was developed based on the results of previous studies, and then modified after performing pilot study. Information on the symptoms possibly related with CTDs was obtained using a self-reported questionnaire from 465 automobile assembly workers. Their job conditions were examined to assess risk factors through both direct observation and video analysis. Results : Rate of detecting risky job through CERF-1 was 85.6%, and was similar to that (88.8%) by Occupational Safety and Health Adminstration(OSHA) checklist but higher than that (63.7%) by American National Standards Institute(ANSI) Z-365. Relationship of the exposure scores derived from CERF-1 with levels of symptom was greater (r=0.49) than OSHA(r=0.28) and ANSI Z-365 (r=0.22). Considering the relationship, jobs scoring higher than 16 could be classified as the Risk Job, and lower than 16 as then Low Risk Job. Sensitivity and specificity of the Risk Job were 92.5% and 31.5 %, respectively. Odds ratio (OR) after age adjus-tment was 5.69 (95% confidence interval 3.15-10.29) for the Risk Job, and these ORs were significantly different from those of the Low Risk Job. The exposure scores were quite valid, in that the scores at the main survey were significantly correlated with those at the follow-up survey, as suggested by test-retest(r=0.88) and inter-rate reliability(r=0.80) Conclusions:The CERF-1, developed in this study, will be an efficient tool for evaluation of risk jobs for CTDs in automobile assembly lines, and can be used easily by health care providers.

籠球選手 疲勞回復을 위한 魚腥草 服用의 檢證 : 高校 男女 選手를 中心으로

이윤근,권세환 중앙대학교 스포츠과학연구소 2000 體育硏究 Vol.- No.13

It is considered the most of sport drinks that the lack of a herb medicine. We tried to verify of a baseball plyer's the recover from fatigue through the taking an'u sung cho' which have great an effects in the internals. It was based on the fatigue survey report by subjective symptoms that an object to the high school baseball plyer(man:26 woman:24). 1. After taking that, it is showed to helpful the function of the respiratory organs, the muscular system, a joint, recover from fatigue. 2. It is good for mental state, nerve system that has nothing to do with ability to carry out directly, so it served keep a balance and comfortable mental state. 3. A period of 1 month, it is great an effects physically, mentally, nerve system add to other things about the recover from fatigue. 4. It should required to be in the spotlight as a sport drink thet 'u sung cho' follow-up the study of medically, nutritionally.

직장인 여가활동 및 건강관리에 관한 연구

이윤근,성중기 중앙대학교 스포츠과학연구소 2001 體育硏究 Vol.- No.14

The purpose of this study is suggesting the data for increasing healthy of employee by analyzing their reaction to health life and control. Employee of 320(male 160. female 160) were surveyed about healthy life and control by questionnaire. Almost half of them(48.18%) were usually concenned about their healthy condition(48.18%). On the contrary they were less concerned were 37.95% of them. They have leisure time about 4 hours per day in common(60.07%) and they said that they were in good health(58.42%). They thought the effects of sports activity were stress consumption(33.33%), increasing appetite(23.33%) and increasing power(20%), and trainer to instruct them(21.45%). Finally they wanted to live in the community which have facilities to be even(39.93%) and open a health class as a fixed period(38.61%).