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      • Genetic Diversity of Korean Rice Breeding Parents as Measured by DNA Fingerprinting with Simple Sequence Repeat (SSR) Markers

        Song,Moon-Tae,Lee,Jeom-Ho,Lee,Sang-Bok,Cho,Youn-Sang,Ku,Ja-hwan,Seo,Kyoung-In,Choi,Seong-ho,Hwang,Heung-Goo 한국자원식물학회 2003 Plant Resources Vol.6 No.1

        Molecular markers are useful tools for evaluating genetic diversity and determining cultivar identity. Present study was conducted to evaluate the genetic diversity within a diverse collection of rice accessions used for Korean breeding programs. Two hundred eighty-seven rice cultivars, composed of temperate japonica, tropical japonica, indica, and Tongil-type of Korean crossing parents were evaluated by means of 15 simple sequence repeat (SSR) markers. A total of 99 alleles were detected, and the number of alleles per marker ranged from 4 to 11, with an average of 6.6 per locus. Polymorphism information content (PIC) for each of the SSR markers ranged from 0.2924 to 0.8102 with an average of 0.5785. These results, with the result that use of only 15 SSR markers made all rice cultivars examined could be uniquely distinguished, imply the efficiency of SSR markers for analysis of genetic diversity in rice. Cluster analysis was performed on similar coefficient matrics calculated from SSR markers to generate a dendogram in which two major groups corresponding to japonica (Group I) and indica and Tongil type rice (group II) with additional subclasses within both major groups. The narrowness of the Korean breeding germplasm was revealed by the fact that most of the Korean-bred and Japan-bred temperate japonica cultivars were concentrated into only 2 of the sub-group I-1 (143 cultivars) and I-2 (58 cultivars) among six sub-groups in major group of japonica. This is because of the japonica accessions used in this study was a very closely related ones because of frequent sharing of the crossing parents with similar genetic background with synergy effect of the inherited genetic difference between indica and japonica. A rice breeding strategy with the use of molecular markers was discussed for overcoming of genetic vulnerability owing to this genetic narrowness.

      • 노은 중학교 기본 계획 연구

        宋容浩,盧相延,金美善 충남대학교 지역개발연구소 2000 地域開發論叢 Vol.12 No.-

        Considering the aim of our education : upbringing the creative Korean leading in the 21C, it is true that there is no effort to cope with the change of education environments. In this point of view, this study aims to suggest the developing model as following the change of educational curriculum, and suggests the planing design of Noh-Eun middle school located on the Noh-Eun district, You-Sung, Tae-Jeon metropolitan. This design is endowed with flexibility in order to adapt both usual with Variation type and Department type to Individual Interactive Learning Approach(IILA) as the 7th curriculum and new educational surroundings.

      • SCOPUSSCIEKCI등재

        척수로 전이된 후두엽 다형성 교아세포종 : 증례보고 A Case Report

        윤상민,송재욱,이창훈,조경자,김종현,이승훈 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.3

        The tendency of glioblastoma to metastasize to the cerebrospinal fluid(CSF) is well documented, reaching approximately 20% in autopsy series. Nevertheless, clinical symptoms from spinal seeding seem to be infrequent or are at least rarely diagnosed. The authors report a case of 41-year old female patient with a cerebral glioblastoma multiform who developed paraplegia due to a pathologically confirmed spinal matastasis.

      • SCOPUSSCIEKCI등재

        재발한 희돌기 교세포종에 대한 BCNU-CDDP 연속정주 화학요법

        윤상민,이창훈,이승훈,송재욱,김종현 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.3

        Eight patients with recurrent oligodendroglioma were treated with 1.3-bis(2-chloroethyl) nitrosourea(BCNU) and CDDP continuous infusion chemotherapy. They were 5 with benign oligodendrogliomas and 3 with anaplastic oligodendrogliomas. All the recurrent tumors had been treated with surgery and radiotherapy. Four patients had already received chemotherapy with ACNU. Seven of them showed response to continuous infusion chemotherapy. The time from the response to progression was 15 to 67 weeks. No severe complication of the chemotherapy was found. In conclusion, BCNU-CDDP continuous infusion chemotherapy is an effective treatment modality in recurrent oligodendrogliomas.

      • 오래 잠그어 둔 수도에서 유출되는 철분의 함량

        송도미,이승희,신연욱,장혜경,오경숙,전현 효성여자대학교 가정대학 학도호국단 1984 家政大論集 Vol.3 No.-

        This study given here presents the results of an experimental investigation of the iron contents contained in the city water which not used for a long time in the winter. The measurements were performed after turning on and for flowing water in a moment. And the quantitative analysis was studied by chemical form and the results were as follows. 1. The content of the ferrous ion was 113.8-14.4 ppm, water soluble iron was 22.5-14.4 ppm and acid soluble iron was 150-10 ppm. 2. Iron contents of the each chemical from gradually reduced but it appeared high value than standard value of city water until five minutes.

      • Effect of Temperature Associated with Early Growth Stimulus on Shortening of Heading Dates in Rice

        Song,Moon-Tae,Lee,Jeom-Ho,Cho,Youn-Sang,Hwang,Hung-Goo 한국자원식물학회 2002 Plant Resources Vol.5 No.2

        The heading date is known to be controlled by two kinds of genetic constituent, photosensitivity and basic vegetable phase. For the latter, the effect of temperature in early growth period is critical to determine the shortness of vegetative growth periods in plant s life. A phytotron experiment on 55 rice cultivars, consisting of two ecotypes of rices, indica and japonica, was conducted at high and low temperature treatments at early growth stage to investigate the possible role of plant growth stimulus by high temperature to associate with shortening of heading date. The high temperature during the early growth stage stimulated the rice growth as measured by plant height with much difference of the growth response between indica and japonica. The conclusive finding that these growth stimulus in early growth stage was highly correlated with the acceleration of heading is, more or less, correlated with the heading of the late growth stage although we could not conclude the genes for early plant growth stimulus by high temperature is the same genes as the genes for accelerating of heading in the late growth stage of plants.

      • KCI등재
      • ICR계 마우스에서 홍화씨 에탄올 추출물의 급성독성시험

        황윤환,박병권,임종환,김명석,송인배,명노일,정상일,윤효인 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2008 動物醫科學硏究誌 Vol.15 No.1

        The present study was carried out to investigate the potential acute toxicity of safflower seed by a single oral dose in ICR mice. Twenty animals of each sex were randomly assigned to four groups of 5 rats each and were administered singly by gavage at dose levels of 0, and 2,500 mg/kg bodyweight. Mortalities, clinical findings, and body weight changes were found and complete gross postmortem examinations were performed. Throughout the study period, no treatment-related deaths were observed. There were no adverse effects in clinical signs, body weight, and gross findings at any dose tested. The results showed that the single oral administration of safflower seed did not cause any toxic effect at the dose levels of 2,500 mg/kg in rats and the minimal lethal dose was considered to be over 2,500 mg/kg body weight for both sexes.

      • KCI등재
      • KCI등재

        자일리톨 껌 저작에 의한 유치 우식증 예방효과 비교분석

        한성근,최연희,손은영,송근배,김영진,남순현 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.2

        자일리톨 껌 저작에 의해 어린이들의 유치우식증 예방효과를 평가하기 위하여 3개 어린이집에서 만 5~6세 어린이 123명을 최종 선정하였다. 자일리톨 껌을 씹는 군(42명), 솔비톨 껌을 씹는 군(42명) 그리고 아무런 조치도 취하지 않은 대조군(39명)으로 나누어 12개월 동안 하루 5회씩 껌을 저작하게 한 다음 구강검사와 우식활성 검사를 통해 유치우식증 예방효과를 비교 분석 하였다. 12개월 동안 대조군 어린이들에서는 dfs index가 5.19개면 증가하였고 솔비톨 군에서는 2.96개면이 증가한 반면 자일리톨 군에서 2.62개면이 증가하여 대조군에 비해 자일리톨 군은 47.1%가 감소하였고 솔비톨 군에서는 43.6%가 감소한 것으로 나타났다. Dentocult-SM strip 검사 및 site strip 검사 결과 모두에서 대조군에 비해 자일리톨 껌과 솔비톨 껌을 씹은 군의 아동들에서 우식활성도가 공히 감소되었다. 따라서 본 연구와 같은 집중적인 자일리톨 껌의 저작 사업은 대상자들과 부모들의 사업에 대한 호응도가 높았고, 사업 시행이 다른 국책 구강보건사업에 비해 용이하였으며 특히 유치우식증 예방적인 측면에서 효과적인 것으로 나타났다. The effect of xylitol and sorbitol chewing gums on dental caries levels among 5-year old kindergarteners was investigated. Three kindergartens the operations of which were partly subsidized by municipal government of Daegu city, Korea, were chosen as the study sites. The child base of the kindergartens were considered demographically and ethnically similar, representing middle-income families. The subjects were examined at their own kindergarten by the two dentists. Participation in the program was voluntary. Over 12 months, 123 participants chewed xylitol chewjng gums(X group; 42 subjects), sorbitol chewing gum@ group; 42 subjects), or did not receive chewing gum as a control group(C group: 39 subjects). Consumption of xylitol and sorbitol was 4.5 to 5.0 g/day/subject, consumed in five daily chewing episodes of 5 min. Oral examination, Dentocult-SM test and interproximal dental plaque collection were completed at baseline and 12 months later. The dmfs of group C increased 59.2%. but group S increased 33.4% and group X increased only 31.3% during 12 months study period. The caries prevention ratio was 47.1% at group X and 43.6% at group S. There also appeared the reduction of caries activity at group X(1.39), group S(1.50) than control group(1.79). Compared with groups S and C, there was a statistically significant reduction of S. mutans in interproximal plaque in group X. The results suggest that xylitol chewing gum can prevent dental caries of deciduous dentition, and may be a little more effective than a sorbitol-containing product in controlling some caries-associated parameters in kmdergarten-age subjects.

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