정신분열병환자의 뇌량에 대한 신경병리적 고찰 : 확산텐서영상(Diffusion Tensor Image)기법의 적용

이경진,신용욱,하태현,이종민,김인영,김선일,문원진,정은철,박해정,오정은,박지영,강경훈,권기원,권준수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.4

Objectives : Diffusion tensor imaging (DTI) is a new technique that can be used to visualize and measure the diffusion of water in brain tissue. It is particularly useful for evaluating white matter abnormalities. In this paper, we investigated the neuropathology of the corpus callosum in patients with schizophrenia through the new methods, diffusion tensor imaging. Methods : Diffuse tensor imaging was performed in 19 schizophrenic patients and 26 healthy controls. One complementary measure, fractional anisotropy (FA), which is considered to be sensitive indices of axonal integrity, was obtained from regions of interest in the five areas of the corpus callosum. Neuropsychological measurement also underwent for measurement of frontal lobe function in two groups. Results : There were no significant differences of FA in the DTI measures for either the schizophrenic patients compared with controls. FA was significantly decreased in women compared with men. Neuropsychological measurements such as Wisconsin card sorting test were correlated with FA of patients with schizophrenia. Conclusion : FA measures revealed no differences between schizophrenia and controls. The findings suggest that the structural integrity of white matter in patient with schizophrenia was not disrupted. The results are discussed in relation to previous studies reporting positive and negative findings. It is concluded that further studies using DTI in larger samples, improved and standardized methods of data acquisition and analysis are needed.

한국인 관상동맥의 변화양상에 대한 형태학적 연구

권태정,이상용,이한영,고영창,권기석,조재홍,김태공,김유훈,조갑래,서중석,이원태 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

한국에서의 간질의 사회적 낙인

이상암,유희정,허경,박형국,신동진,송홍기,정원영,권오영,이성수,김요식,김성은,이병인 대한간질학회 2002 대한간질학회지 Vol.6 No.2

한라산 주변에 발생하는 Karman Vortex Street 재현

권지혁(Kwon Ji-hyuk·Lee),이연원(Lee Yeon-won),김영덕(Kim Young-duk),박광열(Park Kwang-yul) 한국풍공학회 2006 한국풍공학회지 Vol.10 No.1

늦가을과 초본 사이 제주도 후면에 Karman vortex street가 발생한다. 이러한 vortex가 발생하기 위해서는 기온 역전층과 5 ~ 13 m/s의 지속적인 바람이 필요하다는 것을 밝히기 위한 많은 연구들이 있었다. 이러한 vortex clouds는 발생 후 주 풍향의 방향을 이동하게 된다. Karman vortex street는 기상학에서 매우 흥미로운 주제이다. 본 연구에서는 LES 난류 모델을 이용하여 Karman vortex street에 관한 해석을 수행하고 수치해석을 통해 얻은 결과와 기상 데이터가 일치함을 보였다. From late autumn to the beginning of the spring, the phenomena of the Karman vortex street have been frequently observed in the wake of Mt. Halla in the Jeju island. Some researches revealed that the necessary conditions for development of these vortex clouds are a strong low-level inversion of temperature and a persistent wind speed of 5 to 13m/s. After the cloud is formed, the vortex clouds are shed from alternating sides of Jeju island and then move downwind with main airflow stream. The Karman vortex street in the wake of the Jeju island was one of the interesting topics in meteorology. In this study, CFD using LES turbulence model was developed to investigate the Karman vortex street and the results of CFD showed a good agreement with weather data.

工業敎育大學 敎育改善에 관한 硏究(Ⅲ)

宋周鎬,李昌岬,洪元杓,孟琦錫,任洪彬,李廷玟,李載元,李來烈,權五憲,金振淳,李文洙 충남대학교 공업교육연구소 1982 論文集 Vol.5 No.1

This paper aims at providing a concrete plan to improve technical and vocational teacher education in the College of Industrial Education of Chungnam National University. It is intended to propose a practical four-year regular and short-term course. Also, the estimated required facilities is included in this study as well as their management. The main conclusions and recommendations are summarized as follows; 1) The numbers of students enrollment should be reduced to 220 students which is the approximate number of future demand. 2) In order to offer to the students a broader education and to cope with the increase/decrease in demand of technical and vocational teacher within a specific field, the 8 department existing at the present (Department of Architecture Engineering Education, Civil Eng. Educ., Metallurgical Eng. Educ., Mechanical Eng. .Educ., Electrical Eng. Educ., Electronic Eng. Educ., Industrial Chemistry Educ. and Industrial Technology Educ.) would be combined into 5 (Department of Construction Engineering Education, Mechanical Eng. Educ., Electrical Eng. Educ., Industrial Chemistry Educ. and Industrial Technology Educ.). 3) The short-term course program is recommened to provide additional training and education to those candidates who already have experience in technical fields to meet an occasional demand. 4) It is necessary to add the Teaching Profession Section in the administrative organization of the College.

P247 : A study on use of complementary and alternative medicine for acne

( Sook Kyung Lee ),( Taek Geun Lee ),( Hyun Hwang Bo ),( Tae Gwang Kwon ),( Se Won Jung ),( Young Seok Lee ) 대한피부과학회 2013 대한피부과학회 학술발표대회집 Vol.65 No.2

Background: Complementary and alternative medicine (CAM) is any practice that has healing effects, but is not based on evidence demonstrated by scientific method. Recently, CAM has been used in various diseases including acne. However, there have been no studies on CAM for acne in Korea. Objectives: The purpose of this study was to analyze the use of CAM in acne patients. Methods: A total of 159 patients with acne were enrolled on the study, and filled out a questionnaire about use of CAM. Results: Overall 87.4% (139/159) of the patients reported the previous or current use of at least one more type of CAM. Cosmetics for acne (100, 22.9%) was most frequently used, followed by diet therapy (81, 18.5%), spa and bath therapies (77, 17.6%), health food supplement (67, 15.3%), skin care shop (64, 14.6%), oriental medicine (38, 8.7%), and aromatherapy (9, 2.1%). The most common reason for using CAM was ``wish to try everything`` (28.6%), and the most common source of information was internet (40.5%). The therapeutic effect of CAM was best with diet therapy (32.1%). The most common side effect of CAM was aggravation of symptoms. The most common monthly cost for CAM was between 50,000 and 100,000 won/person. Conclusion: As our results, we can predict that the use of various types of CAM for acne will become more common. Therefore, dermatologists need to study about benefits and adverse effects of CAM for acne.

저령차전자탕(猪苓車前子湯)의 기원(基源), 변천과정(變遷過程) 및 구조원리(構成原理)

권오원,김배수,이지원,신승원,이의주,Kwon, Oh-Won,Kim, Bae-Su,Lee, Ji-Won,Shin, Seung-Won,Lee, Eui-Ju 사상체질의학회 2016 사상체질의학회지 Vol.28 No.2

Objectives This paper investigates the origin, the progressive changes and the constructive principles of Jeoryoungchajeonja-tang(猪苓車前子湯).Methods Jeoryoungchajeonja-tang and other related prescriptions were analyzed in terms of their pathological indications, based on previous literature including 『Sanghannon(傷寒論)』, 『Keumkuaeyoryak(金匱要略)』, 『Donguibogam(東醫寶鑑)』, 『Donguisusebowon‧Sasangchobongwon(東醫壽世保元‧四象草本卷)』, 『Donguisusebowon‧Gabogubon(東醫壽世保元‧甲午舊本)』, 『Donguisusebowon‧Sinchukbon(東醫壽世保元‧辛丑本)』Results and Conclusions 1) The origin of Jeoryoungchajeonja-tang is discovered in the prescriptions for Lee-su(利水), that is, Jeoryoung-tang(猪苓湯). 2) Ohryoung-san(五苓散) introduced in 『Donguisusebowon‧Sasangchobongwon(東醫壽世保元‧四象草本卷)』progressively transformed into Shihosaryoung-san(柴胡四苓散)(『Donguisusebowon‧Gabogubon(東醫壽世保元 ‧甲午舊本)』) and ultimately into Jeoryoungchajeonja-tang(『Donguisusebowon‧Sinchukbon(東醫壽世保元‧辛丑本)』), a prescription appropriate for usage in the Mangeum symptomatology(亡陰證). 3) The Jeoryoungchajeonja-tang is composed of 10 herbs. Of these, Notopterygium incisum Ting(羌活), Aralia cordata Thunb.(獨活), Schizonepeta tenuifolia Briq.(荊芥), Saposhnikovia divaricata Schischk.(防風) make the Pyoeum(表陰) drop, and Anemarrhena asphodeloides Bge.(知母), Gypsum fibrosum(石膏) scatter the uihwa(胃火), and Poria cocos Wolf.(茯苓), Alisma canaliculatum(澤瀉), Polyporus umbellatus Fr.(猪苓), Plantago asiatica L.(車前子) facilitate urination.

유방암 환자에서 Tc-99m Tetrofosmin Scintimammography의 진단적 유용성

이광만,원종진,최시성,박기한,김창근,이종덕,윤권하 대한핵의학회 1999 핵의학 분자영상 Vol.33 No.5

Purpose: The purpose of this study was to evaluate the diagnostic usefulness of scintimammography performed with Tc-99m tetrofosmin in the detection of primary breast cancer. Materials and Methods: Sixty-one patients underwent Tc-99m tetrofosmin scintimammography, plain-filrn mammography and ultrasonography. After intravenous injection of Tc-99m tetrofosmin (740 MBq), prone lateral and anterior scintimammograms were obtained. Scintimammogram was visually interpreted as positive, probably positive, probably negative and negative for malignancy. The tumor to background count ratio (T/B) was measured at 5 minutes and 1 hour. Plain-film mammogram was interprcted as one of 5 categories. Final diagnosis was achieved by surgical histology (58/61) or fine needle aspiration (3/61). Of 61 patients, 44 had cancer and 17 had benign lesion. Tumor size of malignant and benign lesions on ultrasonogram were 2.51 ±1.30 cm (range 1-8 cm), 2.50 ±1.35 cm (range 0.96-6 cm), respectively. Results: The sensitivity of plain-film mammography was 88.6%, specificity 58.8%, positive predictive value 84.7%, and negative predictive value 66.7%. The sensitivity of Tc-99m tetrofosmin scintimammography was 90.9%; specificity, 88.2%; positive predictive value, 94.9%; negative predictive value, 78.9%. Of 25 patients with indeterminate degree of suspicion for malignancy on plain-film mammogram, 23 were correctly diagnosed by scintimamography. The T/B at 5 minutes and 1 hour were 3.78 ±2.21, 3.25 ±1.80 respectively. The T/B was decreased significantly at 1 hour (p$lt;0.001). Conclusion: Tc-99rn tetrofosrnin scintimammography was useful diagnostic procedure in the detection of primary breast cancer, especially in patients with indeterminate degree of suspicion for malignancy on plain-film mammogram. (Korean J Nucl Med 1999;3.3:452-460)

보리등겨로 제조한 간장의 향기성분

권오준,이은정,최웅규,손동화,이석일,정연건,지원대 한국위생과학회 2002 한국위생과학회지 Vol.8 No.2

새로운 장류제품으로서 보리등겨의 이용방안을 모색하기 위하여 간장을 만들어 연구하였다. 보리로 제조한 간장의 갈색화는 점차적으로 증가 하였으며 완만한 변화를 보였다. 향기성분으로는 4-vinyl-2-methoxy-phenol, benzeneacetaldehyde, palmitic acid, 2-furancatboxaldehyde, methyl-9, 12-octadecadienoate, di-(2-ethylhexyl)phthalate, diethyl phtalate, dibytyl-1,2-benzenedicatboxylate, 5-methyl-2-furancarboxaldehyde, 3,4-dimethyl-1h-pyrazole, phenylethyl alcohol, dioctyl-hexanedioate, dimethyl-1,2-benzenedicatboxylate, benzaldehyde, methional, 2-methoxy-phenol, n-furfurylidene-3-methylbutyl amine, 1-furfuryl-2-formyl pyrrole, tetradrcanoic acid, 5-methyl-pyrimidine, 4-methyl-5-hydroxymethyl-imidazole, maltol, 5-(5-methyl-2-furanyl)methyl-2-furancarboxaldehyde 순으로 높은 함량을 차지 하였다. For investigation of new utilization as jang-products, kanjang was prepared using barely bran. This study was conducted to investigate flavor components of kanjang during fermentation time. The optical density was gradually increased. Among the flavor components identified in kanjang made with barley bran, the contents of 4-viny1-2-methoxy-phenol was the most in quantity followed by benzeneacetaldehyde, palmitic acid, 2-furancarboxaldehyde, methyl-9,12-octadecadienoate, di-(2-ethylhexyl)phthalate, diethyl phtalate, dibutyl-1,2-benzendicarboxylate, 5-methyl-2-furancarboxaldehyde, 3,4-dimethyl-1h-pyrazole, phenylethyl alcohol, dioctyl-hexanedioate, dimethyl-1,2-benzenedicarboxylate, benzaldehyde, methional, 2-methoxy-phenol, n-furfurylidene-3-methylbutyl amine, 1-furfuryl-2-formyl pyrrole, tetradecanoic acid, 5-methyl-pyrimidine, 4-methyl-5-hydroxymethyl-imidazole, maltol and 5-(5-methyl-2-furanyl)methyl-2-furancarboxaldegyde.

진해 일대 조류의 종 다양성

이원호,장지덕,최병인,강성룡,김성진,권기정 동아대학교 부설 기초과학연구소 2004 基礎科學硏究論文集 Vol.21 No.1

본 연구은 진해항 일대의 조류상을 조사ㆍ분석한 것이다. 조사는 2001년 12월부터 2002년 4월까지 28회를 조사하였다. 센서스 기간 중 총 61종의 조류를 조사 지역내에서 관찰할 수 있었으며, 연 55,115개체가 관찰되었다. 종수의 합계와 총 개체수 그리고 종별ㆍ개체별 출현 빈도에서 유도된 종 중요도는 불은부리갈매기[0.58], 괭이갈매기[0.14], 흰죽지[0.12], 고방오리[0.07], 민물도요[0.07], 참새[0.06], 재갈매기[0.06]가 중요한 종으로 나타났다. 월별 최대 관찰 개체수는 2001년 12월에 46종 5,993개체를 관찰하였으며, 2002년 1월에 37종 7,105개체, 2월에 37종 8,837개체, 3월에 38종 4,106개체, 그리고 4월에 32종 2,819개체를 관찰하였다. 종 풍부도는 4월에 가장 높게 나타났으며, 종 다양성과 균등도는 1월이 가장 높게 나타났다. 월별 종의 유ㆍ무와 개체수를 비교하여 양방향 유사도를 분석한 결과 2월과 3월의 조류 군집이 유사한(0.69: Pearson Correlation Index) 것으로 나타났고, 다음으로 1월(0.617), 12월(0.522)로 12, 1, 2, 3월이 하나의 cluster를 형성하고 있었으며, 4월이 틀린 cluster를 형성하고 있다. 수금류, 섭금류, 갈매기류, 참새류 등 4가지 중요 군집으로 구분하여 개체수를 비교한 결과 66%가 붉은부리갈매기 외 3종의 갈매기류였고, 21%가 혹부리오리 외 13종의 수금류, 7%가 붉은머리오목눈이 외 21종의 참새목, 5%가 흰물떼새 외 5종의 섭금류, 1%미만의 맹금류, 논병아리류, 가마우지류의 조류로 나타났다. We investigated the abundance and local distribution of birds, in four areas of the jinhae. Data were collected from four areas in the jinhae from 2001 to 2002. In this study, 55115 individual birds of 80 species were censused. We evaluated important species with abundance of birds were as follows: Black-headed Gull[0.58], Black-tailed Gull[0.14], Pochard[0.12], Pintail[0.07], Dunlin[0.07], Tree Sparrow[0.06], and Herring Gull[0.06]. The number of species and individuals in each month were recorded as follows: 5993 individual birds of 46 species in December(2001), 7105 individual birds of 37 species in January(2002), 8837 individual birds of 37 species in February, 4106 individual birds of 38 species in March, 2819 individual birds of 32 species in April. In study period, the april was the highset richness(R' =0.60) and the January was the highest diversity(H'=2.08) and evenness(E5=0.52) with an expected species number of E[S_(818)]=29. Pairwise similarity declined with increasing distance between recording month and recording month from two different clustered separately in a UPGMA cluster tree. Comparison of population variable at 4 sites of 4 classes was compared as follows: 1.Gull(66%), 2. Waterfowl(21%), 3. Passerine(7%), and 4. Wader(5%).