백서 심근경색모델에서 시간경과와 경색의 크기에 따른 심자도의 변화

김미성(Mi Sung Kim),박영선(Young Sun Park),권순길(Sun Gil Kwon),지정훈(Jeong Hoon Ji),신종성(Jong Sung Shin),오광식(Kwang Sik Oh),양용모(Yong Mo Yang),연태진(Tae Jin Youn),김동운(Dong Woon Kim),조명찬(Myeong Chan Cho),이용호(Yong Ho 대한내과학회 2002 대한내과학회지 Vol.62 No.1

N/A Background: Magnetocardiogram (MCG), which records the changes of magnetic fields generated by the heart`s electrical activity, theoritically can provide unique data for clinical application. To date, MCG has been investigated only at a single time point after myocardial infarction (MI) with severe left ventricular dysfunction in rats. The purpose of the present study was to investigate sequential changes of MCG after MI and to evaluate effects of infarct size on MCG. Methods: Acute MI were induced by the permanent ligation of left coronary artery in 22 rats. Magnetic fields were recorded just above a rat with Nb Superconducting Quantum Interference Device (SQUID) gradiometer inside a magnetically shielded room. MCG was measured before and immediately after surgery and it was subsequently recorded at the time points of 1, 4 and 6 hours post operatively. MCG was also measured at 1, 3, 7 and 21 days after surgery. Results: Elevation of ST segment and appearance of pathological Q wave on the MCG were evident immediately after the ligation of coronary artery and persisted to 6 hours after MI. On MCG, ST segment was depressed and T wave was inverted from 1 day after MI. In rats with small-and moderate- sized MI (infarct size〈30%), ST depression returned to near the isoelectric level and Q wave disappeared from 7 days after MI. However, ST depression and Q wave were still present in rats with larger infarct (infarct size≥30%). Conclusion: Evolutional changes of MCG were well-recognized up to 21 days after MI. Furthermore, the infarct size can be expressed by the extent of Q wave and ST segment depression on MCG. Taken together, these data indicate that MCG is a helpful modality for the diagnosis, evaluation of infarct size and follow up after MI.(Korean J Med 62:42-48, 2002)

심근경색의 위험인자로서 Thrombomodulin유전자변이의 의의

박현영,김영미,권혁문,지선하,조승연,정남식,심원흠,장양수 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.6

얼굴 실인증으로 발현된 우측 우성의 의미치매 환자 : 증례보고 A Case Report

권재철,안선영,박영진,최미영,강수진,나덕렬 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Semantic dementia (SD) is a temporal variant of frontotemporal lobar degeneration (FTLD). Clinical manifestation depends on which hemisphere is predominantly involved Left side predominant group presents with naming difficulty and decreased auditory comprehension of words, whereas the right side predominant group presents with prosopagnosia. We report a 61-year-old right-handed woman presented with a 6-month history of impaired ability to recognize familiar faces of her acquaintances she used to know well She scored 25/30 on Mini-Mental State Examination. Neuropsychological tests showed impairments in visuospatial, memory, and naming function When presented with photographs of 25 famous people in Korea such as politicians, sports star, actors or actress, the patient could not tell their name at all and identify occupation only 7 of 25 people. But 6age/education matched controls showed correct responses of names in 12.3±4.1 and occupation in 20.8±3.2 of 25 people. Her brain MRI showed atrophy in both anterior temporal areas, more marked on the right side. We consider this patient as the first case of right side dominant SD reported in Korea

원료콩의 증자조건을 달리한 검정콩 간장의 유리당, 유기산 및 지방산의 변화

권선화,최재훈,고영란,손미예,박석규 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3

콩의 증자조건에 따른 검정콩 전통간장의 숙성 후 유리당, 유기산, 지방산조성을 조사하였다. pH 값은 5.04~5.32로 시험구간의 큰 차이를 나타내지 않았고, 원료 콩을 상압증자한 검정콩 간장이 가압이나 스팀보다는 약간 높은 수치를 나타내었다. 적정산도는 4.26~7.73mL로 나타났으며, 가압증자한 검정콩 간장(4.26~5.61mL)이 가장 높았으며, 다음으로 상압(7.32mL), 스팀(5.99~6.96mL)의 순으로 나타났다. 환원당은 25.18~194.81㎎%로 나타났고, 상압이 25.18㎎%로 가장 낮았으며, 가압이나 스팀증자한 검정콩 간장의 경우 상호간에는 큰 차이가 없지만, 상압한 것보다는 7~8배 높은 함량을 나타내었다. 주요 유리당은 glucose, fructose, xylose였으며, 스팀증자한 검정콩 간장이 상압이나 가압보다 각각의 유리당 모두가 많았고, 상압증자는 유리당이 극히 미량으로 검출되었다. 주요 유기산은 succinic acid, oxalicaicd, tartaric aic, malic acid, citric acid였고, 총 유기산은 스팀증자 (40.38~76.96 ㎎%)한 검정콩 간장이 상압(55.85㎎%)이나 가압(27.78~34.21)한 것보다 많았다. 증자 처리시간이 길수로 가압과 스팀으로 처리하여 제도된 검정콩 간장은 약간씩 감소되는 경향을 나타내었다. 주요 지방산은 palmitic acid(33.28~43.51%), stearic a창(14.15~19.16%), myristic acid(5.03~19.14%)였으며, 전체 지방산 중에 55.97~72.85% 비율을 차지하였고, 원료 콩에 존재하지 myristic acid가 상당히 많이 존재하였다. pH values in all samples were in the range of 5.04 to 5.32. pH of kanjang prepared with normal pressure(HPK) was higher than that of kanjang prepared with high pressure(HPK) and kanjang prepared with steam(SPK). Titratable acidity(TA) in all samples were found to be 4.26∼7.72 mL. TA in HPK(5.99∼6.96 mL) was lower than that in SPK(4.26∼5.61 mL) and NPK(7.32 mL). Reducing sugar(RS) contents in all samples were in the range of 25.48 to 194.81 ㎎%. Rs contents of HPK and SPK were a similar pattern and were higher than that of NPK. Major free sugars(FS) were glucose, fructose and xylose. In total FS, SPK was higher than that of NPK and HPK. Major organic acids(OA) were succinic acid, oxalic acid, tartaric acid, malic acid citric acid. OA contents in HPK and SPK were decreased slightly according to the heating time of whole black bean. The highest percentage of fatty acid(FA) in all samples was palmitic acid(33.28∼43.51% as area % of GC chromatogram), followed in a decreasing order by stearic acid(14.15∼19.16%) and myristic acid(5.93∼19.14%). The composition ratios of three FA to total FA ranged from 55.97 to 72.85%. In all samples, there was myristic acid that was not contained in raw soybean.

우반구 뇌 손상 후 나타난 연축성 발성장애 1예

권미선,심현섭,정선주,이재홍 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.1

Spasmodic dysphonia (SD) is a kind of focal dystonia of larynx and it is calssified into three subtypes:adductor type, abductor type, and mixed type. The etiology of SD is not clearly known yet. Cortical dysfunction is regarded as one of the causes of SD based on the clinical data in which patients who showed SD due to the lesion of the central nervous system. The lesions documented so far involve the basal ganglia, supplementary motor area, and thalamus in the dominant hemisphere. We report an unusual case with SD after an ischemic lesion of the precentral gyrus in the right hemisphere, which is rarely mentioned in relation to SD. The characteristics of the symptoms and cortical functions in phonation are discussed.

예비교사의 교육실습에 대한 셀프내러티브 탐구

권선미,조철기 부산대학교 과학교육연구소 2013 교사교육연구 Vol.52 No.1

본 연구는 내러티브 탐구를 적용하여 예비교사가 교육실습기간 동안 겪게 되는 경험은 어떤 것이며, 이러한 경험은 어떤 의미를 가지는가를 알아보았다. 내러티브는 경험을 잘 나타낼 수 있는 도구로써 이를 수집ㆍ분석하기 위해 교육실습생인 연구자의 실습일지와 학생들의 학습일지를 활용했다. 이들 일지에 쓰여진 내러티브는 현장텍스트로서 교육실습생과 학생의 경험이 나타나게 되며, 이러한 내러티브의 의미를 분석한 것이 연구텍스트인데 이를 토대로 연구결과를 도출하면 다음과 같다. 첫째, 교육실습에서 가장 중요한 부분은 수업실습인데, 연구자는 스스로 작성한 실습일지와 학생들이 작성한 학습일지, 그리고 지도교사와의 협의를 통해 수업 전-중-후에 대한 고민과 반성적 사고할 수 있었다. 둘째, 연구자는 내러티브 탐구를 통해 예비교사로서의 한계를 경험하기도 하였지만, 그것은 점점 자신의 교직관을 재정립하게 되는 기제로 작용하였다. 셋째, 연구자는 실무실습이 수업실습에 비해 상대적으로 덜 중요하게 다루어지는 경향을 경험하였다. 그러나 이것은 교육실습을 통해서만 얻어질 수 있는 현장경험이므로 보다 실질적이면서도 비중 있게 이루어질 필요가 있음을 느꼈다. 마지막으로 연구자는 교육실습 초기에는 이론과 실제가 분리되고 있는 듯한 느낌을 받았지만, 내러티브 탐구를 통해 이는 실제로 분절적인 것이 아니라 경험을 통해서 이론을 확인하고 재수정하는 과정임을 깨닫게 되었다. 이러한 측면에서 볼 때, 교육실습에 대한 내러티브 탐구는 교육실습생자신의 경험을 이야기하고 또 이야기하는 과정 속에서 실천적 지식을 체득화하는 계기가 된다는 점에서 의의가 있다고 할 수 있다. The purposes of this study is to apply narrative inquiry to examine the experiences and its meanings that the student (geography) teacher goes through during student teaching. Narrative can be used to express individual experience excellently. So this study collected the student teacher’s teaching journal and students’ learning journals and analyzed their narrative as educational experiences. Narrative written in these journals is a field text showing the student teacher’s experience and students experiences. Research text is to analyze narrative written in the field text to examine meaning of the student teacher’s experience. The results obtained from research text can be summarized as follows: Firstly, a researcher as student teacher could do reflective thinking of teaching through narrative inquiry of the student teacher’s teaching journal, students learning journals and adviser’s comments. Secondly, though the researcher experienced limitations as the student teacher though narrative inquiry, it became gradually positive materials for him or her to be a good teacher. Thirdly, the researcher experienced that an administrative work was apt to be treated less importantly than the student teaching. But the researcher felt that this had to be treated more practically because this could be an experience only through the student teaching. Finally, though the researcher felt that the educational theory and practice was separated in the beginning of the student teaching, he or she thought gradually that it was to identify and to revise the theory through experience. Therefore, narrative inquiry of student teaching means that it is for the student teacher to obtain practical knowledge through the process of telling and retelling of his experience.

16, 17세기의 스페인 문학에서 나타나는 "소설(novela)"의 개념

권미선 서울大學校 스페인中南美硏究所 1995 이베로아메리카硏究 Vol.6 No.-

스페인에서는 16 세기와 17 세기 초반에 엄격한 의미에 있어서의 소설에 관한 이론들을 갖추지 못하였다. 다시 말하자면, 미비하나마 존재하던 그 이론들 조차 독립적인 형태를 취하지는 못하였다. 거의 대부분은 작가들의 서문이나, 극작품, 소설과 같은 한 작품내에서 도덕적, 비평적 성격을 띤, 소설에 관한 이론적 연구 내용이 전부였고, 이것들은 거의<시론>의 내용들을 나름대로 각색한 것이었으며, 또 다시 이 시론은 수사학으로부터 많은 영향을 받고 있었다. 소설은 이미 체계를 갖춘<시론>의 이론을 빌려 왔으나, 그다지 좋은 성과는 이루지 못 하였다. 시학에는 서사시, 서정시, 극시의 세 장르에 관한, 그것도 모두 산문이 아닌, 시로 쓰여진 장르에 관한 언급만 있었기 때문이다. <시론>은 그레코, 로마시대부터 존재하던 문학이론인데 비하여, 소설은 르네상스 시대에 새롭게 태어난 근대적인 장르로서, 그 당시 도덕가들이나 신학자를 비롯한 거의 대부분의 지식계층으로부터 천대시 받던 장르로, 그 이론을 연구할 만큼 문학적 권위가 그다지 큰 것은 아니었다. 오늘날 20세기에 누리는 소설의 인기와 권위는 19세기가 되어서야 가능했다고 볼 수 있다. 그럼 12, 13 세기 중세 때부터 폭발적인 인기를 얻었던 기사 소설이나 르네상스시대의 목가 소설, 바로크 시대인 17세기에 선풍을 일으켰던 피카레스크 소설의 "소설(novela)"은 어떤 의미의 용어인가? 20 세기에 와서 우리가 편의상 기사 소설, 목가소설, 피카레스크 소설 등 "소설"이라 명칭을 붙이지만, 그건 "소설"의 명칭이 갖는 특유의 신축성 때문이다. 아직까지도 비평가들 사이에서는 단편, 중편, 장편 소설에 대한 규정조차 확립되어 있지 않은 것만 보아도 알 수 있을 것이다. 그러나 우리가 17세기로만 거슬러 가 보아도, 그 당시에는 기사 소설, 목가 소설, 피카레스크 소설과 같은 장편의 작품에는 "소설"이란 용어를 사용하지 않았다.

파종시기가 다른 일미찰의 등숙 중 호화 특성 비교

김미정, 박효진, 이유영, 김선림, 김정태, 우관식, 권영업, 정일민 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

This study was conducted to investigate the pasting properties of waxy corn ‘Ilmichal’ during ripening with different sowing date. Starch content of Ilmichal was increased as matured (p<0.05). Analysis of pasting properties with waxy corn starch using a rapid visco analyser (RVA) showed linear changes in peak viscosity, trough viscosity, final viscosity, breakdown and consistency according to ripening. There were significantly positive correlation between starch content of Ilmichal and peak viscosity (0.39*), trough viscosity (0.58***), final viscosity (0.58***), and consistency (0.57**). Differential scanning calorimerty (DSC). The enthalpy of gelatinization was increased as ripening. But onset and peak temperature were decreased. There were significantly positive correlation between starch content of Ilmichal and onset temperature (0.44*), peak temperature (0.38*), and completion temperature (0.59***), on the other hand, crude protein content presented significantly negative correlation between completion temperature (-0.41*).

불소함유 그라프트 공중합체의 표면특성

차미선,소원욱,박인준,김동권,이수복,ShiYuan, Cheng 한국공업화학회 2003 응용화학 Vol.7 No.2

The graft copolymer, consisting of a flurorinated macromer(F-macromer) and a 2-(dimethyl amino)ethyl methacrylate, were prepared by marcromonomer technique and radical copolymerization. In this study, the surface propeties of the graft copolymer and its additive effect on the surface energy of polymer film were compared with the random copolymer of poly(perfluoroalkyl ethyl acrylate)-r-poly(2-dimethylamino ethyl methacrylate)(PFA-r-P(2-DMAEMA)). The contact angles of the surface modified by the graft copolymer is large than that of random copolymer with similar FA monomer content, and surface free energy of the substrate containing 0.01wt% of the graft copolymer is similar with that of 0.1wt% random copolymer surface. That is, The low-energy modification effect of the graft copolymer is better than that of the random copolymer.

일 지역 중학생들의 분노표현양식과 신체증상에 관한 연구

김남선,권미경 관동대학교 의과대학 의과학연구소 2005 關東醫大學術誌 Vol.9 No.1

The purpose of this study is to provide basic data needed in the nursing intervention for middle school students by examination of the level of anger expression style(anger-in, anger-out, anger control) and physical symptoms of the subjects and measurement of correlation between two. Data were collected from June 13, 2005 to June 17, 2005 and subjects were 200 middle school students in G city. Anger expression style were measured by the Korea adaptation of the State-Trait Anger Expression Inventory(STAXI-K) revised by Lee & Cho(1999) and it is comprised of total 24 questions. As a measuring instrument of physical symptoms was used by Moon(2003). Data were analyzed using the SPSS 10.0 program and included descriptive statistics, t-test, ANOVA and pearson correlation Coefficient. The results of this study are as follows: 1. The mean score for anger-control was 2.92±.42, anger-in was 2.46±.49, and anger out was 2.12±.61. 2. The mean score for physical symptoms was 2.28±.74. 3. There were significant differences in the anger control according to the seniority of brothers and sisters(F=3.286, p=.022) and records(F=4.939, p=.008). There were significant differences in the anger-in according to the grade(F=4.886, p=.009), religion(F=3.441, p=.0120 and records(F=3.380, p=.036). There were significant differences in the Anger out according to the records(F=3.666, p=.027) and friend relation(F=2.893, p=.037). There were significant differences in the physical symptoms according to the grade(F=7.254, p=.020). 4. The data shows significant correlations between anger expression style and physical symptoms(r=.219, p=.000), between anger-in and physical symptoms(r=.271, p=.000), between anger control and physical symptoms (r=.155, p=.038). As a result of this study, the level of anger expression style in the middle school students tends to be higher than comparative research outputs. And the results meant that the higher anger expression level, the more physical symptoms. Accordingly, nursing intervention to reduce the anger expression of middle school students are needed.