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      • 전도도계의 제작에 관한 연구

        강용환,최석남,박병빈 공주대학교 사범대학 과학교육연구소 1980 과학교육연구 Vol.12 No.1

        A low-cost student type conductance meter have been developed for the measurement of conductivity of electrochemical system. This instrument measures an impedance range from ?? Ohm with 2% accuracy. And this instrument could be applied to measure the rapid chemical reaction.

      • 생체분해성 망막압정을 이용한 망막고정에 대한 실험적 연구

        김용백,민병무,김창식,박근성,김승영,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

        Biodegradable retinal fixation devices obtain mechnical fixation of the retina with desirable chorioretinal scarring and with the potential for local, sustained release of antimetabolites and steroids to inhibit proliferative vitreoretinopathy. We manufactured a biodegradable retinal tack with barb that was designed in order to prevent intrusion from implantation of retinal tacks. This study was carried to evaluate the efficacy for retinal fixation and the capability for sustained release of drugs with a newly designed biodegradable retinal tack Biodegradable retinal tacks were made of polymers of glycolic acids and were designed with barbs in a shape to prevent the disinsertion. Biodegradale retinal tacks are divided into 3 parts, a conical portion that is inserted into the sclera, a cylinder portion that remains in the vitreous, and a neck portion between the pin and the cylinder. The tapered conical end was manufactured to allow easy insertion through the retina and choroid into the sclera. A cylinder portion was manufactured with a tapered angle that fixes firmly into the orifice of 19 gauge spinal needle. A neck portion, 0.4 mm in diameter, was designed to prevent disinsertion from following implantation of retinal tack. The applicator was a 19 gauge spinal needle and its orifice was prepared to 15°angle to accept the tapered cylinder portion of the retinal tack. The retinal tacks, secured in the needles, were passed through the formed vitreous and inserted into the retina, choroid, and sclera and were released by pushing the internal needle, usually within 2-3mm of the medullary ray of the posterior rabbit retina A retinal tack was placed in each of 8 pigmented rabbit eyes. Slit-lamp biomicroscopy, indirect ophthalmoscopy and fundus photography were performed periodically from 1 day to 8 weeks after surgery. Eight eyes were enucleated and studied by light microscopy at 8 weeks. Biomicroscopic evaluation of the animals revealed edemas adjacent to the retinal surfaces immediately after insertion of the biodegradable retinal tacks in all the animals. These edemas disappeared after 1 week. The first noticeable change in the size of retinal tacks was shown after 2weeks. The size of the retinal tacks gradually got smaller, decreasing to about one-half at 4 weeks and about one-third at 8 weeks. All retinal tacks remained in inserted places without any movement for an 8 week period. On light microscopy, epiretinal proliferations were seen to extend into the vitreous cavity. Cellular capsules that lined the inner aspect of the scleral defect caused by tack insertion were found. However the adjacent retina had a normal cytologic appearance and architecture in all specimens. We manufactured a biodegradable retinal tack that is designed to prevent intrusion from implantation of retinal tacks. All biodegradable retinal tacks reduce in size with time, but no retinal tacks extruded from the inserted place. The newly designed biodegradable retinal tack can be used for retinal fixation and may be used as a vehicle for the introduction of pharmacologic agents to prevent the cellular events that promote proliferative vitreoretinopathy.

      • 생체분해성 고분자를 이용한 사시수술용 제형개발 및 효용성에 대한 연구

        민병무,김용백,김승영,김창식,박근성,길숙종,조항진,이성복,노승무,송규상,강대영,조준식,양준묵,정경수,최선웅,이진호,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

        A new device, muscle clamping system was developed to facilitate exact quatifying technique A strabismus surgery, and reduce the risk of complications. The device is composed of a lower fixing body with three jaws and an upper supporting body. They are used to clip an extraocular muscle and fix it to the sclera with a single bite. Superior rectus recession on 16 rabbit eyes were performed with this new device. Conjunctival injection, muscle adhesion strength, and light microscopic findings were examined at 1, 2, 4 and 8 weeks postoperatively. The Conjunctival injection were minimal, adhesion power ranged from 420 to 600 gram gravity, which is sufficient in withstand the normal pull of human extraocular muscle. In microscopic exam, some Inflammatory cells and fibrosis were found. The new device was technically easy, fast, and accurate, so it may be useful in stabismus surgery.

      • KCI등재후보

        국내 다기관에서 조사한 지역사회획득 메티실린내성 황색포도알균의 빈도와 임상적 특성

        송진수,최평균,송경호,조재현,김성한,방지환,이창섭,박경화,박경운,신수,최희정,김의석,김동민,이미숙,박완범,김남중,오명돈,김의종,김홍빈,최강원 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

        목적 : 최근 전세계적으로 지역사회획득 메티실린내성 황색포도알균(community-associated methicillin-resistant Staphylococcus aureus, CA-MRSA)의 보고가 증가하고 있다. 하지만, 우리나라에서는 CA-MRSA 감염증에 대한 증례보고만 있을 뿐 아직까지 체계적인 연구결과가 없는 실정이다. 저자들은 국내에서 CA-MRSA의 빈도, 감염증의 임상적 양상, 분리된 균주의 항균제내성 양상을 조사하였다. 재료 및 방법 : 2005년 1월부터 2005년 6월까지 7개 병원에서 MRSA가 분리된 환자의 명단을 파악한 후 의무기록지와 건강보험심사평가원의 자료를 검토하였다. 외래나 응급실에서 혹은 입원 후 72시간 이내에 균주가 분리되고 MRSA 획득과 관련된 위험인자가 없는 경우 CA-MRSA로 정의하였으며, 분리된 균주의 임상적 의미에 따라 원인병원체(pathogen), 집락화(colonizer), 미결정(undetermined)으로 분류하였다. Penicillin과 oxacillin을 제외하고 3개 이상의 다른 계열 항균제에 내성이면 다제내성으로 정의하였다. 결과 : 연구기간동안 총 3,251주의 황색포도알균이 분리되었으며, 이 중 MRSA는 1,900주(58.4%)였다. MRSA 가운데 CA-MRSA는 114주(6.0%) 였으며, 이들이 분리된 부위는 귀(62주), 비뇨기계(14주), 피부 및 연부조직(11주), 호흡기계(10주), 혈액(3주) 등이었다. CA-MRSA 균주 가운데 집락균은 22주, 원인병원체는 22주였으며, 나머지 균주에 대해서는 그 임상적 의미를 결정할 수 없었다. 항균제 감수성 검사를 시행한 73균주 중 47주(64.4%)는 다제내성이었다. CA-MRSA 감염증 22예 중 피부 및 연부조직 감염(9예)과 중이염/외이도염(9예)이 가장 흔하였다. 침습적 감염증(invasive infection)은 4명(원발성 균혈증 3예, 감염성 관절염 1예)에서 확인되었지만, CA-MRSA 감염증으로 사망한 환자는 없었다. 결론 : 병원내 감염증에서는 MRSA가 심각한 문제이지만, 아직까지 지역사회 감염증에서 CA-MRSA는 흔하지 않았다. Background : Methicillin-resistant Staphylococcus aureus (MRSA) infection has emerged in patients who do not have the established risk factors. In Korea, little is known about the epidemiology and clinical features of community-associated MRSA (CA-MRSA). Material and Methods : Clinical microbiology laboratory databases of 7 hospitals were reviewed to identify the patients from whom MRSA was isolated during the period of January to July 2005. Only one isolate per patient was enrolled. In order to identify the risk factors of MRSA acquisition, the medical records and the Health Insurance Review Agency databases were reviewed. CA-MRSA was defined as MRSA isolated from patient without established risk factors. We analyzed patient demographics, underlying medical conditions, characteristics of infection, and antimicrobial susceptibility profiles. Results : Of total 3,251 S. aureus isolates, 1900 (58.4%) were MRSAs. Of the MRSA isolates, 114 (6.0%) were CA-MRSA. Of 114 CA-MRSA isolates, 22 (19.3%) were colonizers, 22 (19.3%) were pathogens, and the clinical significance of remaining 70 (61.4%) could not be determined. Median age of the 22 patients with CA-MRSA disease was 47 years. Nine patients had skin and soft tissue infections, 9 ear infections, 3 bacteremia, 1 septic arthritis. Seven patients had underlying medical disease. None died of the CA-MRSA infections. Of the 73 isolates of CA-MRSA, 47 (64.4%) were resistant to more than 3 classes of antibiotics besides β-lactams. Conclusion : Although MRSA is highly prevalent among hospital-associated S. aureus infection, CA-MRSA infections are not common.

      • SCOPUSKCI등재
      • KCI등재

        세기적 대전환과 대안적 교육

        강성빈,강선보,윤명희,강창동,신현석 한국교육과정학회 2000 교육과정연구 Vol.18 No.2

        본 연구는 교육을 근본적으로 그리고 대안적으로 다시 생각하고, 미래사회의 교육장면이 어떤 방향과 관점을 바탕으로 존재해야 할 것인가를 확고히 해야 할 필요성에 입각하여 문헌분석과 관련 전문가 및 현장 교사와의 세미나를 통해, 세계 변화의 성격을 규명하고 한국교육이 나아가야 할 대안적 교육의상을 교육체제, 교육내용, 교육방법 및 교육평가 면에서 분석하였다. 그 결과는 다음과 같다. 세계변화 추세는 정보화, 포스트모더니즘(다원성과 상대성 존중), 수평적 인간관계, 국제·세계화,시장경쟁원리, 환경보존, 탈제도화된 교육체제로 특징지울 수 있다. 이러한 추세 속에서 한국교육의 기본방향은 교육체제면에서 탈제도화된 교육체제가 대두될 것이고, 그 형태는 기존 학교체제의 변화, Cyber교육, 재택교육, 평생교육 등의 형태를 띄게 될 것이다. 교육내용면에서는 개별화교육을 통한 교육의 수월성을 추구하게 될 것이고, 지식의 습득이 아닌 사고의 과정이 중요시되며, 공동체의식 함양과 인성교육이 강조될 것이다. 교육방법면에서는 학습자의 요구가 반영되어 양방향의 교류가 가능한 교육방법이 개발될 것이고, 지식의 구성과정을 중시하게 될 것이며, 이를 위해 각종 교육 인프라의 구축이 뒷받침되어야 한다. 교육평가면에서는 과정중심의 평가가 강조될 것이고, 평가의 투명성이 요구될 것이며, 신입생 선발기준에 대한 자율권이 부여될 것이다. The purpose of this study is to find out alternative educational aspects in Korea adequate to incoming new era. What will be the educational characteristics of 21 century? What should be the Korean educational system, curriculum, ways of instruction and evaluation which is based on the above characteristics? The research is conducted by investigating related articles and seminars which are held with related specialists and teachers. The educational characteristics of new era will be accelerated in information networking, post-modernism(variety and relativity), horizontal relationship, internationalism, the market economy, the protection of environment, and the breakaway from formal educational system. Suggestions for Korean education are given in four ways. In educational system, alternative educational system has to be prepared. The format of this system will be home-schooling, life-long education, cyber education, and some other kinds of schooling in accordance with formative educational system. In educational contents, emphasis will be on the excellency of each individual, the way of thinking rather than the acquisition of knowledge, the community and the humanity. In educational instruction, methods for reflecting learner's needs, supporting two-way communications, emphasizing the process of constituting knowledge rather than knowledge itself will be designed and developed. Structuring various educational infra is required to facilitate the above instructional methods. In educational evaluation, process-oriented evaluation is required compare to product-oriented one. Discretionary of each school for recruitment will be consolidated.

      • Ostwald-ripening sintering kinetics of Pd-based three-way catalyst: Importance of initial particle size of Pd

        Kang, Sung Bong,Lim, Jong Bin,Jo, Donghui,Nam, In-Sik,Cho, Byong K.,Hong, Suk Bong,Kim, Chang Hwan,Oh, Se H. Elsevier 2017 Chemical engineering journal Vol.316 No.-

        <P><B>Abstract</B></P> <P>The sintering rates of commercial and lab-prepared Pd three-way catalysts (TWCs) as a function of the catalyst mileage were examined by CO chemisorption, XRD and TEM. Interestingly, the sintering rates of the Pd catalysts with a larger initial particle size were slower than those with a smaller initial particle size. This moderation of the growth rate of Pd with increasing initial particle sizes was consistent with the Ostwald-ripening mechanism, attributable mainly to the combination of the decrease of the surface tension of the Pd crystallite and the increase of the evaporating activation energy of Pd. Moreover, the variation of the Pd particle size distribution (PSD) observed in the TEM analysis was well predicted by the Ostwald-ripening sintering model in which the sintering kinetic parameter was a unique function of the initial particle size of Pd.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Commercial and model Pd TWCs with larger initial Pd particles sinter more slowly. </LI> <LI> The optimum initial particle size with sintering resistance is around 10nm. </LI> <LI> The Ostwald-ripening mechanism correctly describes sintering rates of Pd TWCs. </LI> <LI> The PSD of Pd is well predicted by the Ostwald-ripening sintering model. </LI> </UL> </P>

      • 강도별 지속 운동이 호흡순환기능, 혈액가스성분 혈청 지질, 카테콜라민 및 초과 산소섭취량에 미치는 영향

        강영석,박철빈 경희대학교 체육과학연구소 1997 體育學論文集 Vol.25 No.-

        The purpose of the present study was two folds: first, to examine the pattern of changes in physiological variables manipulated by the level of aerobic exercise intensities (40%.55% and 70% of Vo2 max); second. the effects of the physiological variables on the volume of EPOC. The physiological variables of interest in this study were respiratory gas (Vo2, heart rate, RQ), blood lactate and glucose, serunl lipids(TG, FFA), and blood gas(pH, PO2, PCO2, EPOC(voluble, maintain time)). The subjects in this study were ten female university students majoring physical education. Their age ranged from 21 to 23 years old. Before the experiment starts, maximal load test was performed from all the subjects In order to determine individual-specific maximum oxygen consumption. During the experiment, the subjects exercised for 20 minutes on the treadmill at each level of exercise intensities. After exercise, the end-point of recovery period was determined by the point which the Vo2 returned to the level of rest. Two-way ANOVA with repeated measures on both factors and correlation analyses were conducted to obtain the results of the experiment. From these analyses the following conclusions was attained: 1.The mean value of EPOC during the recovery period was the highest at the 70% of exercise intensity, followed by the 55% and the 40% (6.34 kcal), As expected, the mean value of energy consumption during the exercise period showed the sable pattern. 2.The time taken from the end-point of 20 min exercise to the level of rest significantly increased as the level of exercise intensity increased. 3.The value of EPOC was positively related to the values of blood epinepirine, triglyceride, pH, PO2 among the 26 measured physiological variables for all three level of exercise intensities. From these results, it can be suggested that when we evaluate the total amount of exercise expenditure during 20-min exercise with the exercise intensity of 40%, 55%, and 70% of Vo2max, we should include the amount of EPOC(about 5%-10%) consumed the recovery period. Moreover, it was found that the energy consumption was maintainde at least 15 to 50 minutes after the end of exercise period when the aerobic exercise was conducted for 20-min with 70%(or less)of Vo2max.

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