HPLP와 사상체질설문(四象體質說問)을 이용(利用)한 근로자(勤勞者)들의 건강상태(健康狀態) 평가(評價)

최문일,이은경,권소희,고광재,서병윤,정재열,장두섭,송용선,이기남,Choi Mun-Il,Lee Eun-Kyoung,Kwon So-Hee,Ko Kwang-Jae,Seo Byeong-Yun,Jeoung Jae-Yeal,Jahng Doo-Sub,Song Yung-Sun,Lee Ki-Nam 대한예방한의학회 2001 대한예방한의학회지 Vol.5 No.1

개인의 건강증진사업을 진행하기 위해서는 건강에 긍정적인 영향을 미치는 생활양식과 생활양식에 영향을 미치는 요인에 대한 역학적 조사가 필요하며 이는 연령집단별로 건강위험인자나 생활양식 및 건강실천행위 등이 모두 다르게 나타나기 때문이다. 체질에 따른 생활양식 등의 차이를 규명하는 것은 체질의학이 예방서비스의 일환으로 적용될 수 있는 기초자료를 제공하는 데 큰 역할을 할 뿐 아니라 체질의학을 현대화하는 데에도 기여할 것으로 사고된다. 이에 본 연구에서는 각 체질을 분석하고 체질별 건강증진 생활양식 실천정도를 파악한 결과 몇 가지 결과를 얻었기에 보고하는 바이다. 1. 연구대상자 중 태음인(太陰人)은 43.7%였고 소음인(少陰人)은 33.6%였으며, 소양인(少陽人)은 22.7%로 나타났다. 2. 연구대상자의 자아실현, 건강책임, 운동, 영양, 대인관계, 스트레스 관리를 포함한 건강증진 생활양식의 총 평균은 138.9이고 총 평점은 2.62이었다. 각 영역별 평점은 대인관계 2.94, 자아실현 2.86, 스트레스관리 2.71, 영양상태 2.68, 건강책임 2.37, 운동영역 2.21의 순으로 대인관계가 가장 높고 운동영역이 가장 낮았다. 3. 건강증진 생활양식 전체영역과의 관계를 보면 여성의 경우와 연령이 높을수록 건강증진 생활양식 실천정도가 높게 나타났다. 건강증진 생활양식 각 영역과의 관계를 보면 성별에서 보면 건강책임영역과 영양영역, 스트레스관리 영역에서 여자가 더 높은 실행정도를 보였고 운동영역에서 남자가 더 높은 실행정도를 보였다(P<0.05). 연령에서는 건강책임영역에서는 30대가, 영양영역과 스트레스관리영역에서는 50대가 가장 높은 실행정도를 보였다(p<0.05). 결혼상태에 따라서는 영양의 영역에서만 기혼자가 유의하게 실행정도가 높게 나타났다(P<0.05). 4. 건강증진 생활양식 각 영역과 사회경제적 특성과의 차이를 보면 월수입에서는 대인관계영역에서만 월수입이 100만원 미만이 가장 높게 나타났고(P<0.05), 교육수준별로는 자아실현영역에서만 교육수준이 높을수록 이행정도가 높게 나타났으나(P<0.05) 나머지 영역에서는 유의한 차이가 나타나지 않았다. 5. 대인관계영역을 제외한 모든 영역에서 태음인(太陰人)의 건강증진 생활양식의 실천정도가 가장 높았으며 자아실현영역에서는 소양인(少陽人)과 거의 비슷했다. 소음인(少陰人)은 건강책임 영역을 제외하고는 모든 영역에서 실천정도가 가장 낮은 것으로 나타났고 건강책임은 태음인(太陰人), 소음인(少陰人), 소양인(少陽人)의 순서로, 대인관계 영역에서는 소음인(少陰人), 태음인(太陰人), 소양인(少陽人)의 순으로 실천정도가 높음을 알 수 있다. Overview: The purpose of this study was to evaluate the determinants on the correlation between constitution and health promoting lifestyle profile on the workers. Also, the questionnaire on the HPLP (health promoting lifestyle profile) of Walker(1987) and Sa-sang constitution of Lee(l894) were utilized Methods: Data from a representative sample of 652 workers were analyzed Pearson's chi-square test analysis was utilized to test the explanatory causal model and to determine the direct and indirect effects of independent variables on quality of life. Results: Constitutional distribution among exposed group, were Tae-eum In(43.7%), So-eum In(33.6%), and So-yang In(22.7%). The degree of the subjects practicing health promoting lifestyle, on a scale of 1 to 4, is an average of 2.62, personal relations 2.94, self-realization 2.86, stress management 2.71, nutrition 2.68, responsibility for health 2.37, and exercise 2.21, with personal relations earning the highest points and exercise the lowest As for factors influencing health promoting lifestyle, there is significant difference between sex and age. That is female and higher age. On the difference between constitution and health promoting lifestyle, Tae-eum In is the highest all area except personal relations. So-eum In is the lowest all area except responsibility for health. Conclusions: Tae-eum In totally do health promoting lifestyle well but So-eum In relatively not. On the Study we used the HPLP(health promoting lifestyle profile) on the premise that each person's daily life, the attitude and the practice level to the health have an influence on the health. So in the constitution there is a little differences in the consideration and the practice level and health condition will be different. On this study we finish up by knowing about the health promoting lifestyle. But on next time we will have to go on studying about the sign and the comparison with the result of western and oriental medical health examination to the each constitution on carrying out continuously oriental medical health examination.

L1210 세포증식에 대한 Glycyrrhizin의 억제작용 기전

殷載淳,徐龍勳,權鎭,柳東和,吳贊鎬,蘇俊魯,全焄,黃甲洙 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

The purpose of this research was to investigate the mechanism of inhibitory action of Glycyrrhizin(GZ) on the proliferation of mouse leukemia cell-line, L1210 cells. The cytotoxic activity was tested using a colorimetric tertrazolium assay(MTT assay), the apoptosis was tested using flow cytometry. Nitric oxide(NO) production form mouse peritoneal macrophage was tested using a Griess method and the phagocytosis of human polymorphonuclear cells was tested using a lucigenin chemiluminescence. GZ ingibited the proliferation of L1210, BALB/c 3T3 cells and mouse thymocytes at 50 ug/ml/ GZ did not affect nitric oxide production from mouse peritoneal macrophages in vitro, but ingibited nitric oxide production from lipopolysaccharide and y-interferon treated macrophages. Macrophages of GZ-administered mice accelerated NO production. The proliferation of L1210 cells apoptosis of L1210 cells were induced by co-culture with macrophage of GZ-administered mice. The apoptosis of L1210 cells were induced by co-culture with macrophage of GZ-administered mice. GZ increased the phagocytosis of human polymorphonuclear cells. These results suggest that GZ inhibit the proliferation of L1210 cells not only as a direct cytotoxic agent o tumor cells, but also by the enhancement of NO production and phagocytic activity.

Cantharis의 세포독성

殷載淳,權鎭,全焄,吳贊鎬,蘇俊魯 우석대학교 의약품개발연구소 1996 藥學硏究誌 Vol.1 No.-

The cytotoxicity of cantharidine(CTD), the main component of Cantharis, and the combined effect of CTD and anti-tumor drugs on HeLa. Hep G2,SK-OV3. KOHS-NP, BALB/c 3T3 cells, mouse splenocytes and human lymphocytes were estiated by MTT colorimetry assay. CTD inhibited the proliferation of anti-tumor cells, BALB/C 3T3, mouse spleen cells and human lymphocytes. CTD increased the cytotoxicity of mitomycin C, cisplatin or mercaptopurine on tumor cells and BALB/c 3T3 cells. These results indicate that cantharidine has the cytotoxicity of tumor cells, fibroblast cells and immunocytes.

자궁암세포(HeLa)에 대한 사군자탕과 수종 항암제의 병용투여 효과

은재순,김현욱,소준노,오찬호,이송재 又石大學校 1993 論文集 Vol.15 No.-

The studies were conducted to investigate the combined effects of Sa Kunja Tang(SKT) and several anti-cancer drugs. The effects of SKT and several anti-cancer drugs on the proliferation of HeLa cells, human cervical cell line, was estimated by MTT colorimetric assays. The SKT extract inhibited the proliferation of HeLa cell at 10^-4g/ml. The inhibitory action of the mitomycin C(MMC), mercaptopurine(MCP) and 5-fluorouracil(5-Fu) treated group, respectively, on the proliferation of HeLa cell was increased by the SKT. When the mice were treated by the MMC, the number of leukocyte was decreased significantly at the 1st and 3rd day, but recovered at the 7th day. In the groups of the MMC treated with the SKT, the number of leukocytes was increased significantly than the group of the MMC treated only at the 3rd day. The SKT extract decreased the thymus weight of mice. The SKT extract increased the number of plaque forming cells(PFC), but the MMC treated group decreased the number of PFC. The combined treatment of MMC and the SKT increased the number of PFC significantly than the MMC treated group. The SKT extract increased the proliferation of T cells, but the MMC treated group decreased the proliferation of T cells. The combined treatment of MMC and the SKT increased T cell proliferation significantly than the MMC treated group. In conclusion, the results presented in this paper suggest that the SKT extract can decrease the dose of anti-cancer drugs on HeLa cell, and recover the side dffects of the MMC, such as leukopenia and immunosuppresion, without any intercalating the anti-proliferative action of the MMC in vivo.

식품영양분야의 심화교육 수요조사 : 부천 및 인천 지역을 중심으로 Focusing on Bucheon and Inchein Area

소명환,조신호,변기원,백재은,이수정 부천대학 2002 論文集 Vol.23 No.-

식품영양분야의 심화교육을 실시하기 위하여 부천 및 인천지역의 식품관련 업체에 근무하는 사람을 대상으로 교육수요에 대한 설문 조사를 실시하였다. 설문조사에 성실하게 응답한 126명중에서 전공심화교육을 긍정적으로 평가하고 기회가 되면 교육을 받겠다고 응답한 사람이 101명(80.2%)이었고, 부정적으로 평가하거나 심화교육을 받을 의사가 없다고 응답한 사람이 25명(19.8%)이었다 심화교육을 희망하는 주된 이유는 전문분야의 부족한 실력을 향상시키고 학점은행제에 의하여 학사학위도 받을 수 있기 때문이었다. 전공심화과정에 개설되었으면 좋겠다고 생각하는 전공과목은 영양상담, HACCP실무론, 식생활과건강, 외식산업창업및경영, 식당경영론, 급식전산실무, 식품및조리원리, 식품재료학, 식품관능검사, 식품품질관리 등이었다. 학정은행제에 교양관련과목으로 개설되면 좋겠다고 생각하는 과목은 PC활용, 재태크론, 전자상거래론, 소자본창업경영, 대인관계심리학, 상담심리학, 운동과 건강 등이었다. The aim of research was to investigate the demand for deepened education of the subjects who work in food related jobs in Bucheon and Incheon area, and to establish the deepened education in field of Food and Nutrition. Subjects were 126 persons, and the results were as follows: 101 persons(80.2%) evaluated positively the deepened education, and answered to be willing to take the course if they have an opportunity for study. 25 persons (19.8%) responsed negatively, or answered not to take the course. The main reasons to select the deepened education are not only to be able to improve the knowledge in major but also to obtain the degree of Bachelor in food and nutrition. The courses they wanted to be opened were as follows: nutrition education, practice in HACCP, food and health, restaurant management, practice in computer related to food service, food science, principles of cookery, food materials, sensory evaluation of food, quality control, etc. The general courses they wanted to be opened were as follows: PC practice, theory of property management, electronic commercial transaction, establishment and management of the small sized capital enterprises, psychology in human relation, psychology in counseling, physical activity and health, etc.

사군자탕이 L1210 세포를 이식한 마우스의 면역세포에 미치는 영향

殷載淳,金大根,柳東和,權鎭,徐龍勳,蘇俊魯,全焄,吳贊鎬 우석대학교 의약품개발연구소 1997 藥學硏究誌 Vol.2 No.-

The purpose of this research was to investigate effects of Sa-Kunja-Tang(SKT) on immune cells of L1210 cell-transplanted mice. The apoptosis and T lymphocytes subopoulation were tested using a flow cytometry, and the proliferation was tested using a MTT assay. Nitric oxide production from mouse peritoneal macrophage was tested using a Griess reagents, and the phagocytic activity of mouse peritoneal macrophage was tested using a lucigenin chemiluminescence. SKT suppressed apoptosis of T-lymphocytes induced by L1210 transplantation. SKT decreased nitric oxide production from mice peritoneal macrophages increased by L1210 transplantation, and the phagocytic activity decreased by L1210 transplantation. These results suggest that SKT suppresses T lymphocyte apoptosis and macrophage activity in L1210 transplanted mice.

子官癌細胞(HeLa)에 대한 血府逐瘀湯과 數種 抗癌劑의 倂用投與 效果

殷載淳,蘇俊魯 又石大學校 1992 論文集 Vol.14 No.-

The studies were conducted to investigate the combined effects of Hyulbu Chuko Tang (HCT) and several anti-cancer drugs. The effects of HCT and several anti-cancer drugs on the proliferation of HeLa Colls, human cervical cell line, was estimated by MTT colorimetric assays. The 50% inhibitory concentrations of mitomycin C(MMC), cisplatin(CPT), mercaptopurine (MCP) and 5-fluorouracil(5-FU) on HeLa cell were 0.313, 0.565, 22.745 and 28.325/㎖, repectively. HCT extract inhibited the proliferation of HeLa cell at 10^-6-10^-3g/㎖. The inhibitory action of the MCP treated group on the proliferation of HeLa cell was increased by HCT and MCP. When the mice were treated by MMC, the number of leukocyte was decreased significantly at the 1st and 3rd day, but recovered at the 7th day. In the groups of MMC treated with HCT, the number of leukocytes was increased significantly than the group of MMC treated only at the 1st and 3rd day. The HCT extract increased the number of plaque forming cells(PFC), but the MMC treated group decreased the number of PFC. The combined treatment of MMC and HCT increased the number of PFC significantly than the MMC treated group. The HCT extract increased the proliferation of T cells, but the MMC treated group decreased the proliferation of T cells. The combined treatment of MMC and HCT increased the T cell proliferation significantly than MMC treated group.

사군자탕이 항암제를 투여한 마우스의 면역세포에 미치는 영향

殷載淳,金大根,柳東和,權鎭,洪鍾星,蘇俊魯,全焄,吳贊鎬 우석대학교 의약품개발연구소 1997 藥學硏究誌 Vol.2 No.-

The purpose of this research was to investigate effects of Sa-Kunja-Tang(SKT) on immune cells of antitumor drugs administered mice. The apoptosis and T lymphocytes subpopulation were tested using a flow cytometry, and the proliferation was tested using a MTT assay. The administration of etoposide. vincristine or doxorubicin increased the apoptosis of T-lymphocytes, but the action of doxorubicin was decreased by the administration of SKT. The administration of etoposide or vincristine decreased helper T and cytotoxic T cells population of T lymphocytes, but the action of vincristine was recovered by the administration of SCT. The administration of etoposide, vincristine or doxorubicin decreased the proliferation of T-lymphocytes, but the action of doxorubicin was increased by the administration of SKT. These results suggest that SKT has a regulative function of T-lymphocytes in anti-tumor drugs administered mice.

프로야구 오버드로우 투수의 견관절 등속성 토크에 관한 분석

소재무,김용일,김효은 한국운동역학회 2002 한국운동역학회지 Vol.12 No.2

야구 경기에서 투수의 투구 동작은 5단계로 구분되어 정의되지만 투구 속도는 어느 부위의 근력에 의해서 좌우되는지 단언할 수 없다. 그러나 최근에 견관절의 회전력 중요성이 강조되고 있으며 몇몇 선행 연구를 찾아 볼 수 있었다. 그래서 빠른 투구 능력과 견관절 회전력에 대한 상관성 분석의 필요성을 갖게 되었다. 따라서 본 연구의 목적은 오버 드로우 투수들의 견관절 내.외측 토크를 3가지 자세에서 측정하여 볼 속도와 관계를 규명하고 기준을 제시할 기초 자료 제공에 있다. 연구 결과 앉은 자세에서 내.외전 최대 토크는 집단 (볼 속도 차이) 간 유의한 차이가 나타나지 않았으며, 누운 자세의 내.외전 최대 토크는 집단간 유의한 차이가 나타나지 않았으며, 선 자세에서도 동일한 결과가 나타났다. 결론적으로 투구 속도와 자세별 내.외전 최대 토크 근력과는 정량적인 차이는 있었지만 상관성은 나타나지 않았다. 그래서 투구 속도에 영향을 미치는 역학적 에너지 동원 체계에 대한 기전 규명의 추후 연구가 기대된다. The purpose of this study was analysis inter relative the ball velocity and isotonic torque of shoulder joint. The subject were twelve overthrow pitcher of professional baseball player. The measurement was used Cybex 6000. The results of this study were as follows : 1. As the siting position of maximal adduction torque of dominant, A group was higher than B group. As the non-dominant, B group was higher than A group for improved angular velocity. There is no significance difference between group. 2. As the siting position of maximal abduction torque of dominant and non-dominant, B group was higher than A group for all measurement. There is no significance difference between group. 3. As the layed position of maximal internal torque of dominant, A group was higher than B group. As the non-dominant was just higher at 180。/sec than B group, B group was higher at 60。/sec and 300。/sec than A group. There is no significance difference between group. 4. As the layed position of maximal external torque of dominant and non-dominant, A group was more higher than B group for all measurement. There is no significance difference between group 5. As the standing position of maximal internal torque of dominant, A group was just higher at 60。/sec than B group, B group was higher at 180。/sec and 300。/sec than A group. As the non-dominant, B group was higher than A group. There is no significance difference between group. 6. As the standing position of maximal external torque of dominant, A group was higher 60。/sec and 180。/sec than B group. But B group was higher 300。/sec than A group. As the non-dominant, B group was higher than A group. There is no significance difference between group.

청피에 함유된 복강 파크로파지의 탐식작용 억제 성분

은재순,김대근,소준노,지옥표 성균관대학교 약학연구소 1998 成均藥硏論文集 Vol.10 No.1

The phagocytic activity of murine peritoneal macrophage was determined by lucigenin chemiluminescence and engulfment of fluorescein-conjugated E. coli particles. The activity-guided fractionation upon the methylenechloride fraction of Aurantii immaturi pericarpium led to the isolation of a flavonoid, isosinensetin, as a suppressive component of phagocytosis, lsosinensetin suppressed the lucigenin chemiluminescence and the engulfment of fluorescein-conjugated E. coli particles and enhanced the production of nitric oxide in murine peritoneal macrophage.