氣功與防止衰老的作用

전신옥,이경섭,남상수,Quan, Xin-Yu,Lee, Kyung-Sub,Nam, Sang-Su 대한예방한의학회 2004 대한예방한의학회지 Vol.8 No.1

The average life span is expanded due to the development of modem society, material and cultural life and increasing level of public health. This means that the aging society is rapidly progressing. Geniatric diseases also have increased due to increasing of the aged population. Along with an increase of the aged patient, the anti-aging, prevention of geniatric disease and quality of life is tending high on social concern and medical issues. Many reports showed the evidence to the positive anti-aging effect of Oriental medicine. Qigong therapy, a kind of Oriental medicine, has been used to prevent aging and life prolongation with positive effect for many thousand years. Therefore, qigong practice is popular and common to middle age and old age in China.

갈근이 비만 랫드 간조직의 비만관련 유전자 발현에 미치는 영향

신윤상,황귀서,Shin, Yoon Sang,Hwang, Gwi Seo 대한예방한의학회 2014 대한예방한의학회지 Vol.18 No.3

Objective : It is known that Pueriaria lobata has an anti-osteoporetic effect, anti-cancer effect, anti-pyretic effect, and anti-diabetic effect. The aim of this study was to evaluate anti-obesity effect of Pueriaria lobata extract (PLE), and elucidate the effect of it on gene expression related to lipid metabolism. Method : The experiments were performed with the use of ovariectomized rats as estrogen-deficient obesity model. They were grouped NC (normal control), OC (estrogen-deficient control), PLH (100mg/kg of PLE), PLL (20mg/kg). PLE was orally administered for 6 weeks. Body weights and serum lipid level were estimated, and real-time PCR was performed to investigate the effect of PLE on gene expression in liver. Results : PLE decreased the body weight and serum cholesterol and triglyceride, but increased HDL-cholesterol. And PLE increased leptin, CYP27, CPT1, CYP8B1, ACAT2, LDLR, and SCD1, but reduced $PPAR{\gamma}$, PGC1A, HMG-CoA-R, ACAT1, SCD1, and APoB gene expression in liver tissue of rat with estrogen-deficient obesity. Conclusion : It is concluded that Pueriaria lobata reduced body weight, and its effect was expressed by regulation of gene expression related to lipid metabolism in rats with estrogen-deficient obesity.

황금(黃芩)과 구성 화합물의 약리작용에 대한 고찰

이건석,박민희,천목은,홍진우,조수인,Lee, Keon-Suk,Park, Min-Hee,Cheon, Mog-Eun,Hong, Jin-Woo,Cho, Su-In 대한예방한의학회 2011 대한예방한의학회지 Vol.15 No.2

Objective : Scutellaria baicalensis is one of the most popular and multi-purpose herb in traditional medicine. It is also useful for its practicability to cultivate in Korea. The purpose of this study is to contribute to researches and applications of scutellaria baicalensis by analyzing and reviewing international researches on the compositions and the effects of scutellaria baicalensis. Methods : This study analyzed 146 articles from PubMed by searching with the keyword "Scutellaria baicalensis", "Huang quin", "Baical Skullcap", "Huang qin", "baical skullcap root", "ogon", "Hwanggeum" and "Hwangkeum", published within the last 10 years(from 2000 to 2009). We reviewed the 146 articles on Scutellaria baicalensis and its active constituents in terms of 'Active constituents', 'Experimental studies', 'Clinical studies', 'Drug interaction', 'Side Effects/Toxicity' and 'Pharmacokinetics'. Results : The active constituents of Scutellaria baicalensis are flavonoids such as baicalein, baicalin, wogonin and oroxylin-A. It is reported that scutellaria baicalensis and its active compounds have antiinflammatory activity, antitumor activity, antioxidant activity, antiviral and antibiotic activity, neuroprotective effects, hepatoprotective effects and cardiovascular effect. Conclusions : This study is aimed to summarize the results obtained within the last 10 years and to contribute to following researches and applications of Scutellaria baicalensis.

당귀(當歸)의 Decursin 성분 분석

황귀서,Hwang Gwi-Seo 대한예방한의학회 1998 대한예방한의학회지 Vol.2 No.1

In oriental medicine, it is well known that Angelica gigantis tonifies and harmonizes the blood, regulates the menses, and moistens the intestines. This herb has been used for deficient blood pattern, menstural problem, abdominal pain, and traumatic injuries in oriental medicine. A major component of Angelica gigantic consist of a various coumarines, decursin, schooltime, umbelliferone, safrole, 3-butylphalide sistesterol. In this study, we aimed to measure the contents of decursin, one of major coumarine derivative, to determine the standardization of Angelica gigantis.

한의사의 감염관리 인식과 교육에 따른 실천도 변화 조사

김주철,성수현,이은경 대한예방한의학회 2021 대한예방한의학회지 Vol.25 No.1

Objectives : This study was conducted to identify the perception level of infection control among Korean medical doctors(KMD) and to examine the comparison of practice level depending on infection control education. Methods : Data were collected from 552 Korean medical doctors. The collected data were analyzed through frequency analysis, chi-square analysis(χ²-test), cross analysis and t-test using SPSS 25.0 program. A measurement variable is perception and practice level of infection, education satisfaction. The maximum significance level was 0.05. Results : First, After infection control education, practice score increased from an average of 2.98 to 3.46. Second, Actual practice before and after infection management education sessions showed high engagement in infection management in Korean medical clinics after the education sessions, with the highest practices in cleaning, disinfection, sterilization management of medical device(4.26) Infection prevention and control during acupuncture, pharmacopuncture, cupping, moxibustion, chuna procedures(4.18), and Hygiene and safety management before dispensing(4.18). Third, Infection management education leading to additional educational at Korean medical institution according to the help received in operating Korean medical institution was shown to be significant(p=0.032). Conclusion : From the results of this study, in order to improve the practice of infectious control of Korean medical doctors, infection control education is essential. The education on infection control is required to Korean medical doctors it would contribute to preventing healthcare associated infections in Korean medicine.

골반교정 치료효과의 국내 임상 연구 경향에 대한 체계적 문헌 고찰

백지유,정명수 대한예방한의학회 2021 대한예방한의학회지 Vol.25 No.1

Objectives : This study attempted to systematically analyze studies of pelvic correction treatment. To grasp it from the overall perspective and evaluate the effectiveness of the treatment, only randomized control studies (RCTs) which correspond to a high level of evidence were selected. Methods : The study included 16 RCTs which were selected by total 695 studies searched in Korean Journal by searching site RISS, NAL, DBpia. Outcomes were assessed by Meta analysis and Cochrane’s Risk of bias tool was used to evaluate the quality of literature. Results : Pelvic correction treatment had a significant effect on the relief of VAS, ODI, flexibility, shoulder tilt, and pelvic tilt. Conclusion : Pelvic Correction proved to have a positive effect. To have more certain result, a method to minimize bias should be considered and designed.

일부 동물성 한약재의 독성과 안전성등급화 - 봉독, 사독, 반묘와 오공을 중심으로 -

박영철,이선동,Park, Yeongchul,Lee, Sundong 대한예방한의학회 2016 대한예방한의학회지 Vol.20 No.1

Objectives : About 13% of the medicines used by traditional korean medicines(TKM), are called animal medicines and are derived from non-herbal sources such as animals and insects. However, the clinical use of these preparations from animal medicines is often based on tradition and belief, rather than on evidence of toxicity and efficacy. As a result, animal medicines containing toxin have caused serious problems from injecting patients with venom. Here, various venoms frequently used as TKM were reviewed in terms of their instinct toxity and tried to estimate their safety classification. Methods : The estimation of safety classification was based on human equivalent dose(HED)-based MOS (margin of safety) and clinical dose applied for patients. Results and Conclusions : Except that of snake venom due to no clinical dose, they were evaluated as class 3 for bee venom, class 4 for cantharidin, toxin from blister beetle, and class 1 for venom from scolopendrid. In conclusion, animal medicines showed a wide range of safety classification from class 1 to class 4. This wide range is estimated to result from extremely limited applications of each venom for patients because of their strong toxicity. However, it should be cautious for application in clinics since animal medicines can produce anaphylactic reactions particularly after veinous administration even with a tiny amount of venom.

한.양방 협진의 진료협력수준 측정도구개발 및 타당도 연구

박민정,최병희,백윤희,박정혜,Park, Minjung,Choi, Byunghee,Baek, Yun Hui,Park, Jeong Hye 대한예방한의학회 2015 대한예방한의학회지 Vol.19 No.1

Objective : The purpose of this study is to present the desirable model for the promotion of care coordination between Korean Medicine and Western Medicine and develope the instrument to measure the level of coordination. Moreover, we verified the validity and reliability of the developed Instrument. Method : In this study, We developed the 16 items regarding care coordination in Korean Medicine and Western Medicine by literature review and expert interviews. In addition, we verified the validity and reliability of the instrument as a methodological research. Results : We developed two factors such as 'Inter-professional activities' and 'Organizational support' as the instrument to measure the level of care coordination, and each of seven, eight total of 15 measurement items are listed. Conclusion : Since the legal permission, the level and type of care coordination and the effects of them are needed to be checked. So, the measurement instrument driven by this study has a political signification in healthcare system specially in these times. In addition, by utilizing this instrument, we propose to perform a variety of future studies on the levels of healthcare coordination and related outcomes.

우즈베키스탄 한방병원에서 진행한 한의약 비만관리 프로그램의 효과

이은경,정명수,유영진,권동현,이준석,장보형,윤진원,박유리,박해모,이선동,고성규,Lee, Eun-Kyoung,Chong, Myongsoo,Ryu, Young Jin,Kwon, Donghyun,Lee, Joonseok,Jang, Bo-Hyoung,Yun, Jin Won,Park, Yu Lee,Park, Haemo,Lee, Sundong,Ko, Seong-Gyu 대한예방한의학회 2015 대한예방한의학회지 Vol.19 No.2

Objective : As part of the Korean Medicine Official Development Assistance(ODA) and Public Health Project, we implemented a obesity management program(OMP) using Korean medicine in Uzbekistan and its follow-up study was conducted to evaluate the effectiveness of the program. Method : We recruited the participants of whose Body Mass Index(BMI) were over $25kg/m^2$ and who agreed to participate in the program at the South Korea-Uzbekistan Friendship Korean Medical Hospital in Uzbekistan. The program consisted of auricular acupuncture, functional food, and education program on diet and exercise. It was provided once a week during 7-week period. Anthropometric measurements and blood test measuring total cholesterol, triglyceride, and glucose were performed at the baseline, the end of the program, and 10-month follow-up. At the end of the program and the follow-up, survey on satisfaction and self-evaluation of the effectiveness of the program was additionally conducted. Results : 43 out of 78 participants completed the program and were included in the analysis. The analysis of the main outcomes showed that there were significant decreases in anthropometric measurements such as body weight, waist circumference, body mass index (BMI) and body fat content as well as blood test including triglycerides, total cholesterol and blood glucose levels. In the follow-up study, 24 subjects participated and 19 subjects (79.1%) reported that they succeeded in weight control. Furthermore, many participants reported that they maintained healthy lifestyles like healthy diet and regular exercise. The satisfaction with the program was also relatively high, and the education program was selected as the most motivating intervention for weight control. The outcomes such as body weight, BMI, body fat content, and blood glucose level were maintained to be at the decreased level; however, waist circumference, total cholesterol and triglycerides levels either returned back to the baseline level or were elevated to the level higher than the baseline. Conclusion : This study suggests that the OMP using Korean medicine may contribute to weight control of obese population in Uzbekistan. It is meaningful in that the study shows the possibility of implementing health promotion programs using Korean medicine in other countries with different cultures. In the future, more efforts to evaluate the effectiveness of the programs using rigorous methodologies and utilize the effective programs in ODA project will be needed.

四象體質 不變論에 對한 理論的 檢討

최찬헌,윤대환,임진석,백진웅 대한예방한의학회 2008 대한예방한의학회지 Vol.12 No.2

It is very important problem that exactly distinguish constitution, in Sasang constitutional Medicine. But, it is careless that discuss the propriety of ‘Sasang constitution unchangeability theory(四象體質 不變論)’. The foundation of Sasang constitution unchangeability theory is the sentence in DongUi SuSae BoWon Sa-dan theory(東醫壽世保元 四端論): “The Organ system of Taeyang(太陽), Taeum(太陰), Soyang (少陽) and Soeum(少陰) is the variation of YinYang(陰陽), is firm nature and is unnecessary agreement.(太少陰陽之臟局 陰陽之變化也 天稟之已定 固無可論)”. But, the foundation of Sasang constitution unchan- geability theory contradict the theory that Organ system(臟腑) is made by deviation of emotions(joy, anger, sorrow and pleasure:喜怒哀樂) or temperament(性情). Because these emotions is revealed after birth(後天), the deviation of Organs system made by deviation of emotions is not innate, is acquired after birth. Therefore, it is necessary to discuss the opinion that Sasang constitution is variable after birth. The conclusion of our study is that Sasang constitution can be variable after birth.