A Case of Oral Candidiasis Treated with Fluconazole (Diflucan®) Mouthrinse

유동화,박경덕,권혁진,서정완,윤정호,김기호 대한의진균학회 2023 대한의진균학회지 Vol.28 No.1

Oral candidiasis, a common fungal infection in humans, is characterized by the overgrowth of Candida species in the superficial oral epithelial mucosa. The condition is associated with multiple risk factors, including impaired salivary gland function, oral mucosal damage, and long-term antibiotic or corticosteroid use. Several treatment options are available; nystatin and amphotericin B are the most widely used local medications. Recently, fluconazole has emerged as the preferred systemic treatment. We report a case of oral candidiasis in an 83-year-old male diagnosed with bullous pemphigoid in 2017 and previously administered methylprednisolone. He developed oral candidiasis a few months before presentation and was treated with 10 mL nystatin suspension three times daily; unfortunately, the disease was recalcitrant to this treatment and his symptoms showed no improvement over two months. We discontinued nystatin in favor of fluconazole syrup (Diflucan®) administered by rinsing, then swallowing, 5 mL syrup once daily. The lesion improved after one month of treatment. This case demonstrates the efficacy of fluconazole as a primary treatment for oral candidiasis. The act of rinsing the mouth with syrup exposes the oral mucosa to drug, potentially producing a better treatment response than taking the syrup orally without rinsing.

CDMA 이동통신 시스템의 기지국 시스템 로딩 구조 설계 ( The Design of System Loading Architecture for CDMA Base Station System )

유동화,조무호,조철회 한국통신학회 1994 한국통신학회 학술대회논문집 Vol.13 No.2

승마운동 시 품종에 따른 말의 보행 속도 비교

유동화,천영진,오유성 한국운동재활학회 2016 한국운동재활학회 학술대회 Vol.2016 No.05

CDMA 이동통신 운용보전시스템의 로딩 프로세스 구조 및 제어 방법 ( The BSM Loading Process Architecture and Control Method for CMS )

유동화,조무호,조철회 한국통신학회 1995 한국통신학회 학술대회논문집 Vol.14 No.1

태아 허파의 초기 발달 중 과립허파꽈리세포의 분화와 미세구조의 특징

유동화,김대중,김성수,김경용,이원복,Yoo, Dong-Hwa,Kim, Dae-Joong,Kim, Sung-Su,Kim, Kyung-Yong,Lee, Won-Bok 한국현미경학회 1999 Applied microscopy Vol.29 No.3

초기발생중인 태령 9주부터 20주의 사람 태아의 허파 7예에서 과립허파꽈리세포의 분화과정과 미세구조의 특징을 밝히고자 투과전자현미경으로 관찰한 결과는 다음과 같다. 1. 발생 9주와 12주에서 기관지 나무의 상피의 형태로는 과립허파꽈리세포의 분화를 확인할 수 없었지만 발생이 진행되면서 15주 후부터 허파꽈리를 형성할 부위의 상피는 점차 거짓중층상피에서 단순입방상피로 분화하였다. 2. 발생 9주에서 처음으로 뭇층판소체가 관찰되어 과립허파꽈리세포의 분화를 확인할 수 있었다. 이외에도 발생 $9\sim15$주 동안에 이 세포에 특징적인 세포질포함체, 과립상포함체, 뭇소포포함체 그리고 진한포함체 등의 세포내 포함물을 관찰할 수 있었다. 3. 발생 19, 20주에서 뭇층판소체는 수와 크기가 급격하게 증가하였지만 다른 세포내 포함물은 감소되어 있었다. 요약하면 사람 태아의 허파에서 발생 초기단계에 뭇층판소체를 가진 허파꽈리세포(또는 전구세포)가 관찰되었으며, 이외에도 특징적인 다양한 세포내 포함물을 가진 세포들이 관찰되었다. 그러므로 과립허파꽈리세포는 발생 9주 또는 그 이전부터 분화한다고 할 수 있다. The differentiation and ultrastructural characteristics of type II pneumocyte was investigated using 7 cases of human fetal lungs from 9 to 20 weeks of gestation by transmission electron micropscopy. The result obtained were as follows. 1. From the pattern of epithelium, type II pneumocyte was not discernable, but with the gradual development of gestation, the epithelium of the future pulmonary alveoli was transformed from pseudostratified columnar into simple cuboidal epithelium after 15 weeks of geatation. 2. The multilamellar body very specific to type II pneumocyte was observed at first at 9 weeks of gestation. Besides, another characteristics of the cell were also observed such as cytoplasmic inclusion body, granular inclusionbody,multivesicularinclusionbodyanddensebody. 3. The number and size of multilamellar body increased, but those of other inclision bodies decreased at 19 and 20 weeks of gestation. In summary, type II pneumocytes (or precursor cells) with multilamellar body and another characteristic inclusion bodies were observed in the human fetal lungs from 9 weeks of gestation. And so, it is suggested that the differentiation of type II pneumocyte starts at or before 9 weeks of gestation.

사물탕이 L1210 세포 이식 및 항암제를 투여한 마우스의 면역세포에 미치는 영향

유동화,권진,오찬호,은재순,Yu, Dong-Hwa,Kwon, Jin,Oh, Chan-Ho,Eun, Jae-Soon 한국생약학회 1998 생약학회지 Vol.29 No.2

Sa-Mul-Tang(SMT) consist of Rehmanniae Radix Preparata, Paeoniae Radix Alba, Cnidii Rhizoma and Angelicae Gigantis Radix. In L1210 cells-transplanted BALB/c mice, T-lymphocyte apoptosis, $CD8^+T_C$ cells population in thymocyte and nitric oxide production in macrophage were enhanced, but phagocytic activity was decreased. SMT suppressed T-lymphocyte apoptosis and enhanced CD^4+T_H$ cells population, but did not affect nitric oxide production and phagocytic activity in L1210 cells-transplanted mice. In antitumor drugs-injected mice, T-lymphocyte apoptosis was enhanced, but $CD4^+T_H/CD8^+T_C$, cells population and T-lymphocyte proliferation were decreased. SMT suppressed T-lymphocyte apoptosis, and enhanced $CD8^+T_C$ cells population, T-lymphocyte proliferation and phagocytic activity in vincristine-injected mice. These results suggest that SMT enhances T cell-mediated immunity in L1210 cell-transplanted mice, and enhances T cell-mediated immunity and phagocytic activity in vincristine-injected mice.

Stein-Leventhal Syndrome을 동반한 자궁내막선암 1례

유동화,김진홍,주갑순 대한산부인과학회 1987 Obstetrics & Gynecology Science Vol.30 No.3

말의 보행형태에 따른 승마의 운동강도

유동화 ( Dong Hwa Yoo ),오유성 ( Sung Won Youn ),윤성원 ( Mun Jin Lee ),이문진 ( Yoo Sung Oh ) 한국스포츠정책과학원(구 한국스포츠개발원) 2014 체육과학연구 Vol.25 No.4

이 연구의 목적은 말의 보행형태인 평보, 경속보와 좌속보, 구보에 따른 승마의 운동강도(심박수, 산소섭취량, 호흡교환률, 대사량, 에너지 소비량)를 규명하는데 있다. 남녀 승마동호인 15명을 대상으로 4단계(평보, 경속보, 좌속보, 구보)의 과정을 5분씩 기승해서 얻은 심박수 및 호흡가스분석 자료(산소섭취량, 호흡교환률, 대사량, 에너지소비량)를 토대로 각 보행형태에 따른 평균값을 비교하였고, 성별에 따른 승마의 운동강도의 차이를 비교를 통해 다음과 같은 결론을 얻었다. 말의 보행형태별 운동강도에는 차이가 나타났으며, 말의 보행속도가 빨라질수록 운동강도가 증가하는 경향을 보였다. 경속보, 좌속보, 구보의 운동강도는 통계적으로 차이가 없었으며, 이들의 운동강도가 평보에 비해 높은 것으로 나타났다. 승마의 보행형태별 운동강도는 평보가 중강도, 속보와 구보가 고강도로 분류되었다. 말의 보행형태별 남녀 간의 운동강도는 유의한 차이가 나타나지 않았다. 단, 분당에너지소비량에는 남녀 간의 차이가 나타났는데 이러한 결과는 분당 에너지소비량이 남녀 간 체중의 차이에 의해 영향을 받기 때문인 것으로 판단된다. The purpose of this study was to examine the intensity of horseback riding as exercise (heart rate, oxygen intake, respiration exchange ratio, metabolism, energy expenditure) according to the tread of a horse such as walking, rising trotting, sitting trotting, and cantering. In this study, the subjects were 15 amateur horse riders. They participated in a 4-stage process(riding while the horse was walking, rising trotting, sitting trotting, and cantering) while wearing gas masks and heart rate belts for 5 minutes during each stage. Through this study, the average of heart rate, oxygen intake, respiration exchange ratio, metabolism, and energy expenditure in each stage of riding was attained and compared. The result of this study can be summarized as follows. First, the intensity of exercise by horse riding is significantly different depending on the tread of a horse. The intensity of exercise is increased as the speed of the horse’s movements increased. Trotting and cantering show higher intensity than walking. Among the different treads of a horse, walking can be categorized as having an intermediate intensity of exercise, whereas trotting and cantering are categorized into a higher intensity. However, there are no significant differences in intensity between trotting and cantering. Second, there are no significant differences between male female participants in terms of intensity of exercise, but there are differences in the energy consumption per minute. The weight differences between male and female participants may be what cause this difference.

피부질환별 직접면역형광검사의 결과에 대한 분석: 11년간의 단일 기관 후향적 연구

유동화 ( Dong-wha Yoo ),이장훈 ( Jang-hoon Yi ),박경덕 ( Kyung-deok Park ),권혁진 ( Hyeok-jin Kwon ),김기호 ( Ki-ho Kim ),윤정호 ( Jung-ho Yoon ) 대한피부과학회 2024 대한피부과학회지 Vol.62 No.1

Background: Direct immunofluorescence (DIF) is a histochemical technique used to detect tissue-bound autoantibodies and diagnose various immune-mediated skin diseases. Objective: This study aimed to evaluate the sensitivity of DIF for each disorder, and the consistency between clinical, histopathological, and DIF results. Methods: A retrospective study was conducted in 194 patients who underwent skin biopsy and DIF testing at our hospital between January 2011 and December 2021. An antibody panel against immunoglobulin G (IgG), IgA, IgM, C3, C1q, and fibrinogen was used. The concordance rate and κ-coefficient between the clinical, histopathological, and DIF results were evaluated. Results: DIF was observed to be positive in 87 cases; 51 cases of immune-mediated bullous diseases, seven cases of connective tissue diseases (CTDs), 25 cases of vasculitis, and four cases of other diseases. The overall sensitivity of DIF for immune-mediated bullous diseases was 71.8%, which was higher than that of histopathology (64.8%). In CTDs and vasculitis, the overall sensitivities of DIF were 30.4% and 65.8%, respectively, which were lower than those of histopathology (73.9% and 84.2%, respectively). In addition, good concordance among the clinical, histological, and DIF results was observed. Conclusion: DIF is a useful diagnostic method, especially for immune-mediated bullous diseases, lupus erythematosus, and Henoch-Schonlein purpura. However, in other CTDs and vasculitis cases, the sensitivity of DIF is relatively low. Therefore, the diagnostic value of DIF along with clinical and histopathological findings will be maximized only when the DIF test is performed for appropriate diseases. (Korean J Dermatol 2024;62(1):18∼28)

승마 운동 시 말의 품종과 걸음걸이에 따른 보행 속도 연구

유동화(Yoo, Dong-Hwa),오유성(Oh, Yoo-Sung),천영진(Chun, Young-Jin) 한국체육과학회 2017 한국체육과학회지 Vol.26 No.2

The purpose of this study was to calculate the speed according to each walking type using the thoroughbred and warmblood establish the standard speed. For horse riding, ten thoroughbreds and twelve warmbloods were used. The riders arrived at the equestrian court about an hour before the experiment day, and performed a preparatory exercise with a light bare hand gymnastic exercise. After about 20 minutes, they prepared the horses through a lightweight balance, a speedometer, The departure sensor and the arrival sensor were installed at a linear distance of 20 m in the section speed meter(MICRO GAIT WITTY). In order to apply the same criteria at the time of departure and arrival, the sensor was installed at the mouth height of the horse. The riders passed the 20 m distance five times according to the footwork method, and then calculated the mean and standard deviation. During the walk, if the horse deviated from the path or the footwork was changed, it was nullified and re-performed. The data obtained through the experiment were calculated by using the Excel program for 5 mean and standard deviation according to the 4 methods of walking. Based on the total 15 times of data for each breed, the speed difference. The independent t-test was conducted and the significance level was set to .05. The results showed that thoroughbred was slower than warmblood in all walking types and showed a statistically significant difference among all varieties except for canter(p<.05).