정상 성인에서 Amitriptyline이 수면구조와 정신생리적 기능에 미치는 영향

홍성곤,신석철,왕성근 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.1

To investigate the effects of Amitriptyline on sleep structure and psychophysiologic function in normal adults, author applied polysomnography for sleep structure, reaction time for attention and visual analogue test for daytime fatigue, mood and sleepiness to the volunteers. The subjects were 8 healthy young adults, aged from 20 to 24 years old. The results were summarized as follows. 1. In normal adults, there were great individual variations in the ditribution of relative value(%) of sleep structure. 2. Compared with the baseline, total sleep time and sleep efficiency increased significantly in the 2lmg amitriptyline night, and WASO decreased significantly in the second recovery night. 3. Compared with the baseline, the absolute value(minutes) of stage 1 sleep decreased significantly in the amitriptyline, first and second recovery nights, and the relative value(%) of stage 1 sleep decreased significantly in the first recovery night. The absolute and relative value of stage 2 sleep increased significantly in the amitriptyline night. The relative value of slow wave sleep decreased significantly in the first recovery night. 4. Compared with the baseline, the absolute and relative value of REM sleep decreased significantly in the amitriptyline night, the relative value of REM sleep increased significantly in the first and second recovery nights, and REM latency shortened significantly in the first and second recovery nights. 5. Feeling of fatigue, depressed mood and sleepiness increased in the afternoon the day after amitriptyline administration. 6. 1) In the baseline, daytime sleepiness was positive correlation with feeling of fatigue and mood. 2) The day after amitriptyline administration, relative value of REM sleep was negative correlation with feeling of fatigue and sleepiness, daytime fatigue was positive corelation with mood and sleepiness, and daytime mood was positive correlation with sleepiness. 3) In the first recovery day, daytime fatigue was positive correlation with mood and sleepiness, and negative correlation with reaction time, daytime mood was positive correlation with sleepiness, and reaction time was negative correlation with sleepiness. 4) In the second recovery day, total sleep time was positive correlation with the relative value of REM sleep time, the relative value of stage 2 sleep was negative correlation with the relative value of slow wave sleep, the relative value of slow wave sleep was positive correlation with daytime fatigue and mood, daytime fatigue was positive correlation with mood and sleepiness, and negative correlation with reaction time, daytime mood was positive correlation with sleepiness, and reaction time was negative correlation with sleepiness.

이상근증후군에 있어서 치료적 스포츠마사지의 효과

홍성찬,박병근,정동혁 圓光大學校 附設 體力科學硏究所 2002 體力科學硏究 Vol.25 No.1

The purpose of this study is to find out the effects of the therapeutic sports massage(TSM) applied to the patients with Piriformis Syndrome by measuring, assessing and analyzing the changes in intensity and unpleasantness of muscle pains before and after TSM. In the therapeutic sports massage program, such methods as effleurage, petrissage and deep transverse friction were selected as traditional massage treatments frequently used for muscles with pain and spasm. Effleurage and petrissage were applied for 20 minutes in total before and after deep transverse friction treatment. After TSM, the McGill pain questionnaire word list(MPQWL), verbal rating scale(VRS), visual analogue scale(VAS) were used to measure the degree of the pain on the patients. The major findings from this study are as follows; 1. The surveyed patients range from 19 to 71 in age, with highest numbers of 16(34.04%) registered in the thirties and next ones of 11(23.41%) in the forties. Divided by sex, 18 are men and 29 are women totalling 47 with average age of 34.7. 2. There was significant decrease in the numerical values of VAS & VRS and MPQWL after TSM(p<.05). 3. There was significant decrease in the intensity and unpleasantness of pains after TSM(p<.05). 4. From the analysis into chronological changes in the intensity and unpleasantness of pains before and after TSM with ANOVA, it became evident that the longer the period of treatment was, the higher the pains decreases drastically, while significant difference was shown in the intensity and unpleasantness of pains(p<.05). Summed up, it can be generally concluded that TSM is an effective treatment to rid the patients with Piriformis syndrome of pains safely and promptly.

Oil Contents and Fatty Acid Composition of Korean Perilla (Perilla ocimoides L.) Collections

Hong,Seong-Taek,Son,Suk-Yeong,Jong,Seung-keun,Rho,Chang-Woo,Yun,Jong-Sun 한국자원식물학회 2003 Plant Resources Vol.6 No.3

This study was carried out to obtain informations on the variations of oil content and fatty acid composition among 90 Korean perilla collections. Average oil content of 90 perilla collections was 44.2% with a range from 29.7% to 61.9%. Perilla collections with late-maturing, super-large seed and gray seed coat showed higher oil content than other types in general. Average saturated fatty acid content in perilla oil was 9.0% with a range from 8.2% to 10.7%, while average unsaturated fatty acid content varied from 89.3% to 91.8% with a mean of 91.0%. Contents of saturated and unsaturated fatty acids were not related to maturity. There were no differences in the contents of saturated and unsaturated fatty acids according to maturity. Linoleic acid and linolenic acid contents were the highest in the super large-sized group(15.5%) and in the large-sized seed group(61.4%), respectively, while contents of fatty acids among the perilla collections were variable with different seed coat colors. Most of the traits studied were not significantly correlated with oil content, but linoleic acid($\omega$ 수식 이미지-6) content was negatively correlated (r=-0.217*) with linolenic acid(ω-3) content.

운동기간에 따른 혈중지단백대사 및 비만호르몬의 변화

홍성찬,함용기,김영빈,박병근,정동혁,이정윤,권성택 圓光大學校 附設 體力科學硏究所 2003 體力科學硏究 Vol.26 No.2

The purpose of this study is to elucidate the effects of regular swimming exercise on blood lipoprotein metabolism and leptin. In this study, swimming(HRmax 50-75%, 60min/day, 5day/week) was performed and 18 were participated for study during 16 weeks. They were divided into two groups, one group as experimental group(n=9) and the other as control group(n=9). A measured factors were TC, TG, HDL-C, LDL-C and leptin.. All data were expressed as mean± standard deviation by using spss package program(win 9.0), one way anova and independent t-test was used to analyze the difference of exercise duration(0week, 8week, 12week, 16week) between groups. For all statistics performed statistical significance was set at p<.05. After exercise intervention, TC, TG, HDL-C, LDL-C and leptin were found to have more significant effects in the experimental group than control group. This results indicated regular swimming exercise training is beneficial to prevent and treat cardiovascular disease and obesity.

Frozen Shoulder에 있어서 마사지의 치료적 접근

홍성찬,김영빈,박병근,정동혁,이정윤,이동헌 圓光大學校 附設 體力科學硏究所 2003 體力科學硏究 Vol.26 No.1

Painful stiffness of the shoulder is an ill-defined clinical entity that is difficult to assess and delicate to treat. The nomenclature used is broad and includes terms such as frozen shoulder, adhesive capsulitis, focal algodystrophy, stiff shoulder, contracted shoulder, and others. Apart from its idiopathic form, the disease can be initiated by trauma, infection, tumour, radiation, systemic and local metabolic disturbances. Pathoanatomically, the common denominator is an inflammatory vascular proliferation followed by thickening, scarring, and retraction of the joint capsule. The inflammatory process often starts at the rotator interval and may extend to the subacromial space. Clinical diagnosis is based on history and physical examination. Generally the onset of pain precedes the perception of a reduced range of motion by weeks or months. In early stages of the disease, the inflammatory type of pain dominates, i.e., the patient's main complaint ist pain at night. In the later stage, range of motion gradually decreases. Patients do not often complain about reduced motion, probably because of its slow onset. The purpose of this study is to find out the effectiveness of the massage applied to the patients with Frozen Shoulder by measuring, assessing and analyzing the changes in intensity and unpleasantness of pain and range of motion(ROM) before and after massage. Surveyed from Jan. 2001 to December 2002 were 104 patients suffering from Frozen Shoulder. In the therapeutic massage program, such methods as Effleurage, Petrissage and Deep transverse friction were selected as they are among traditional massage treatments frequently used for joints with pain and restricted ROM. Effleurage and Petrissage were applied for 20 minutes in total before and after Deep Transverse Friction. After massage program, the intensity and unpleasantness of pain were measured and analyzed by means of VAS(visual analogue scale)-I and VAS-U, while ROM was measured and analyzed by using Goniometer. The major findings from this study are as follows; 1. The surveyed patients range from 28 to 75 in age, with highest numbers of 44(42.31%) registered in the fifties and next ones of 24(23.08%) in the forties. Divided by sex, 59 are women and 45 are men totalling 104 with average age of 51.4. 2. There was significant decrease in the intensity of pain and unpleasantness of pain after massage(p<.05). 3. There appeared, however, significant increase in ROM after massage(p<.05). 4. From the analysis into chronological changes in ROM before and after massage with ANOVA, it became evident that the longer the period of treatment was, the higher the ROM increases drastically, while significant difference was shown in Abduction and in External and Internal Rotation(p<.05). Summed up, it can be generally concluded that massage is an effective treatment to rid the patients with Frozen Shoulder of pains safely and promptly. This study was conducted to determine more accurate impact of massage. From the above outcomes, it was revealed that massage has proven to reduce the pains, exercising huge influence to increase ROM. It is, therefore, suggested to continue and expand the study on the cure of Frozen Shoulder and to motivate patients, orthopedists, physiatrists, physiotherapists, and sports massagists etc. to consider massage as safest and most efficient pain remedy.

유산소성 운동이 호습순환기능 및 혈중지질에 미치는 영향

홍성찬,박병근,함용주 圓光大學校 附設 體力科學硏究所 2000 體力科學硏究 Vol.23 No.-

The Purpose of this research is to examine the effect of the jogging training duration on cardiorespiratory function and blood lipids. Total 12 woman college students were selected for the subjects of this research, divided into two groups, 6 for the control group(C.G) and the other for the experimental group(E.G : 55-60%HRmax). The subjects of experimental group had 12 weeks jogging program in the given intensity, during which the changes in cardorespiratory function and blood lipids were measured three times, at each end of 4th, 8th and 12th week. The research is concluded as follows. 1. At the end of 12th week, the response of HRrest of cardiorespiratory function was decreased to (p<.05). 2. The response of HDL-C changing in blood lipids at the 12th week was also decreased to (p<.05). From these synthesized results, I came to conclusions that exercise intensity of 55-60% HRmax and minimum 12 weeks training duration are required to change the number of heart beat and the air amount of respiration in resting. Maximum amount of oxygen intaken can be possibly obtained after 8 weeks' training duration. HDL-C and LDL-c used as guide posts for the prevention of adult deceases need 12 weeks' training duration according to 55-60% HRmax. Conspicuous changes in HRmax, T-C, TG couldn't be expected from the exercise intensity and the training duration of this research, therefore, another additional research with proper exercise intensity and training duration will be needed afterward.

유산소성 운동이 혈중지질 및 체지방률에 미치는 영향

홍성찬,김영빈,윤영복,박병근,김유성 圓光大學校 附設 體力科學硏究所 2007 體力科學硏究 Vol.29 No.-

This study is aimed at investigating the effects of aerobic exercise of female college students on blood lipids and body fat percentage. Twelve female students were selected for this study and each 6 of them were alloted into the control group and experiment group. The experiment group underwent jogging for 12 weeks and its effects on blood lipids and body fat percentage were measured at the 4th, 8th and final week of the jogging program. The outcomes of the experiment could be summarized as follows: 1. As for HDL-C due to jogging, the experiment group showed an eminent increase with statistical significance(p<.05). 2. In case of LDL-C following jogging, there was a great amount of decrease in the experiment group after the exercise with statistical significance(p<.05). In sum, it is revealed from the present study that the prescribed magnitude and length of exercise can be of help for HDL-C and LDL-C that have been recognized as indicators for diseases of adult people.

의료용 조합자극기(HAPPY DREAM HM-206DB) 적용이 동결견 환자의 통증과 관절가동범위에 미치는 영향

홍성찬,김영빈,박병근,김유성,이성진,정동혁 원광대학교 체력과학연구소 2008 體力科學硏究 Vol.30 No.1

The purpose of this study is to find out the effectiveness of the HAPPY DREAM HM-206DB applied to the patients with Frozen Shoulder by measuring, assessing and analyzing the changes in pain and range of motion(ROM). Surveyed from Mar. 2007 to Dec. 2007 were 10 patients suffering from Frozen Shoulder. After HAPPY DREAM HM-206DB, the pain were measured and analyzed by means of MPQWL, VAS-I and VAS-U, while ROM was measured and analyzed by using Goniometer. The major findings from this study are as follows; 1. There was significant decrease in the MPQWL after HAPPY DREAM HM-206DB applied(p<.001). 2. There was significant decrease in the VAS-I(intensity of pain) after HAPPY DREAM HM-206DB applied(p<.001). 3. There was significant decrease in the VAS-U(unpleasantness of pain) after HAPPY DREAM HM-206DB applied(p<.001). 4. There appeared, however, significant increase in ROM(abduction, external and internal rotation) after HAPPY DREAM HM-206DB applied(p<.001). From the above outcomes, it was revealed that HAPPY DREAM HM-206DB application has proven to reduce the pains, exercising huge influence to increase ROM. It is, therefore, suggested to continue and expand the study on the cure of Frozen Shoulder and to motivate patients, rehabilitation specialists, and health management specialists etc. to consider HAPPY DREAM HM-206DB application as safest and most efficient pain remedy.

국내에서 분리된 Extended-Spectrum β-Lactamase 생성 Escherichia coli와 Klebsiella pneumoniae의 빈도 및 유형

홍성근,김선주,정성훈,장철훈,조성란,안지영,신종희,이혜수,송원근,어영,염종화,용동은,이경원,정윤섭 대한임상미샐물학회 2003 Annals of clinical microbiology Vol.6 No.2

제2차 엠/브이 사이가(M/V "Saiga")호 사건 : 국제해양법재판소의 1998년 잠정조치 명령 및 1999년 본안 판결 Order of Provisional Measures(1998) and Judgment of Merits(1999) of ITLOS

홍성근 한국외국어대학교 외국학종합연구센터 법학연구소 2004 외법논집 Vol.17 No.-

On 13 January 1998, the Government of Saint Vincent and the Grenadines(St. Vincent) filed a request for the prescription of provisional measures concerning the arrest and detention of the oiltanker M/V "Saiga" and its crew on 28 October 1997 by the customs authorities of Guinea with the Registrar of the International Tribunal for the Law of the Sea(the Tribunal). The request was for Guinea not to interfere with the freedom of navigation and related rights of St. Vincent. It further requested that Guinea immediately comply with the judgment of the Tribunal of 4 December 1997, in the M/V "Saiga" case. The request was based on article 290 of the United Nations Convention on the Law of the Sea(the Convention). Article 290 of the Convention provides that provisional measures may be prescribed by a court or a tribunal if it considers that certain requirements have been met, namely that prima facie the tribunal which is to be constituted would have jurisdiction and the urgency of the situation so requires. On 11 March 1998, the Tribunal delivered its order on the request for the prescription of provisional measures in the case between St. Vincent and Guinea. The Tribunal's decision was unanimous on all measures. In the meanwhile on 22 December 1997, the Government of St. Vincent notified Guinea that it was submitting the dispute in respect of the M/V "SAIGA" to arbitration. Then by Agreement between the parties dated 20 February 1998 (1998 Agreement), the arbitral proceedings instituted by St. Vincent were transferred to the Tribunal. The 1998 Agreement between the Parties provides that the written and oral proceedings before the Tribunal shall comprise a single phase dealing with all aspects of the merits, including damages and costs, and the objection as to jurisdiction raised by Guinea. By the order of the Tribunal of 20 February 1998, the Tribunal accepted the case. The case was entered into the list of cases as "the M/V "SAIGA"(No.2) case(Saint Vincent and the Grenadines v. Guinea) ". The dispute concerns the interpretation and application of the Convention. The proceedings on the merits raised many important issues, including jurisdiction, bunkering of vessels at sea, freedom of navigation, enforcement of customs legislation, contiguous zone, right of hot pursuit, Security Council resolution 1132, damages and costs, etc. After the written and oral proceedings, on 1 July 1999 the Tribunal delivered its judgment on the merits.