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      • A Novel Impedance Measurement Method for Three-Phase Power Electronic Systems

        Qingyu Dou,Zeng Liu,Jinjun Liu,Weihan Bao 전력전자학회 2015 ICPE(ISPE)논문집 Vol.2015 No.6

        Power electronic systems could be unstable due to the interaction between converters. Impedance-based stability analysis is an effective approach to predict stability and to provide design criteria. Therefore significant are impedance measurement techniques, which have been well established for DC systems, but need to be improved for AC systems nevertheless. This paper proposes a novel AC impedance measurement method which injects bipolar pulse at current zero-crossing point. Compared with existing methods, it enhances accuracy and reduces distortion. Simulation and experimental results demonstrate the effectiveness of the novel method.

      • KCI등재

        Loess record of the evolution history of severe sandstorms in the Tengger Desert during the Last Interglacial Period (MIS5)

        Qingyu Guan,Baotian Pan,Na Li,Qiong Li,Jundi Zhang,Shujian Xu,Hongshan Gao,Jia Liu 한국지질과학협의회 2010 Geosciences Journal Vol.14 No.2

        The Shagou loess section recorded the evolution information of severe sandstorms in the Tengger Desert during the Last Interglacial (MIS 5). By analyzing the grain size data of the loess samples using the grain size class-standard deviation, we selected the grain size component between 209 and 550 µm to reconstruct the evolution history of the severe sandstorms in the Tengger Desert during the Last Interglacial. The results indicate that there were at least 12 periods of frequently occurring severe sandstorms in that location over this time period. There were two periods in each of S1SS1 and S1SS2, four periods in S1LL1, three periods in S1LL2 and one in S1LL4. The occurrence frequency and intensity of the severe sandstorms presented a characteristic increase from the early to the late period of the Last Interglacial. Combined with the calcium carbonate results, this evidence suggests that climatic change is closely related to sandstorms. A warm and wet climate could restrict the occurrence of severe sandstorms; conversely, a cold and dry climate easily induces severe sandstorms. Meanwhile, with a warm and dry climate background, the relationship between climatic change and the occurrence of sandstorms is quite complex: severe sandstorms are also able to occur in such a climate. A cold and dry climate, however, does not mean a certainty of severe sandstorms.

      • KCI등재

        Combination algorithm for cracked rotor fault diagnosis based on NOFRFs and HHR

        Yang Liu,Yulai Zhao,Jiyuan Han,Qingyu Meng,Hongliang Yao 대한기계학회 2019 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.33 No.4

        In this paper, a combination algorithm for diagnosing rotor crack fault is presented. Firstly, the nonlinear output frequency response functions (NOFRFs) are used to analyze the severity of crack damage in the rotor system qualitatively. The NOFRFs are obtained by processing the vibration signal through the nonlinear output frequency response functions. Further analysis of the NOFRFs can determine the crack depth qualitatively. Secondly, the position of the crack is then located using the crack position index (CPI) l based on the higher harmonic response (HHR) and the dynamic compliance matrix. The simulation and experimental results show that the G 2 (j2w F ) in NOFRFs is very sensitive to crack depth, and the crack position index (CPI) l can determine the shaft segment effectively where the crack is located. The advantage of this combination algorithm is that it can detect the crack faults by measuring the vibration signal of the cracked rotor at two speeds, which makes the measurement process more simplified and reduces the measurement time for real-time monitoring. At each speed only the vibration response of the two nodes need to be measured, which greatly reduces the number of sensor used in the measurement process and reduces the cost of monitoring. The combination algorithm can diagnose cracked rotor faults effectively and has certain application value in the diagnosis of cracked rotor fault.

      • KCI등재

        Transcriptome Sequencing Reveals the Potential Mechanisms of Modified Electroconvulsive Therapy in Schizophrenia

        Wanhong Peng,Qingyu Tan,Minglan Yu,Ping Wang,Tingting Wang,Jixiang Yuan,Dongmei Liu,Dechao Chen,Chaohua Huang,Youguo Tan,Kezhi Liu,Bo Xiang,Xuemei Liang 대한신경정신의학회 2021 PSYCHIATRY INVESTIGATION Vol.18 No.5

        Objective Schizophrenia (SCZ) is one of the most common and severe mental disorders. Modified electroconvulsive therapy (MECT) is the most effective therapy for all kinds of SCZ, and the underlying molecular mechanism remains unclear. This study is aim to detect the molecule mechanism by constructing the transcriptome dataset from SCZ patients treated with MECT and health controls (HCs).Methods Transcriptome sequencing was performed on blood samples of 8 SCZ (BECT: before MECT; AECT: after MECT) and 8 HCs, weighted gene co-expression network analysis (WGCNA) was used to cluster the different expression genes, enrichment and protein-protein interaction (PPI) enrichment analysis were used to detect the related pathways.Results Three gene modules (black, blue and turquoise) were significantly associated with MECT, enrichment analysis found that the long-term potentiation pathway was associated with MECT. PPI enrichment p-value of black, blue, turquoise module are 0.00127, <1×10<sup>-16</sup> and 1.09×10<sup>-13</sup>, respectively. At the same time, EP300 is a key node in the PPI for genes in black module, which got from the transcriptome sequencing data.Conclusion It is suggested that the long-term potentiation pathways were associated with biological mechanism of MECT.

      • Study on Optimization of Energy/Animal/Food/Fertilizer/Environment Ecosystem in Rural Area in the North of China

        ( Ren Wentao ),( Liu Qingyu ),( Moonki Jang ) 한국농공학회 2007 한국농공학회 학술대회초록집 Vol.2007 No.-

        Energy/Animal/food/fertilizer/Environment ecosystem (four-in one ecosystem) in rural area in the North of China means an integration of vegetable production, animal husbandry, fertilizer and biogas production inside greenhouse. The four-in one ecosystem has taken the place of a traditional farming industry, and has developed and has applied during nearly twenty years. The four-in one ecosystem for rural ecological environment and agricultural comprehensive productivity have been improved and upgraded.But with the development of rural economy, improving of people's living standards, a higher demand to the ecosystem is needed. This paper will analyze problems in the process of applying the ecosystem and optimizing the structure and functions in order to provide technical support to further promote the building of rural ecosystem.

      • KCI등재

        Quantitative Reduction of Basilar Invagination With Atlantoaxial Dislocation by a Posterior Approach

        Jian Guan,Fengzeng Jian,Qingyu Yao,Chenghua Yuan,Can Zhang,Longbing Ma,Zhenlei Liu,Wanru Duan,Xingwen Wang,Xuefeng Bo,Zan Chen 대한척추신경외과학회 2020 Neurospine Vol.17 No.3

        Objective: This study evaluated the feasibility and efficacy of quantitative reduction and fixation to treat basilar invagination (BI) with atlantoaxial dislocation (AAD). Methods: Posterior occipitocervical angle (POCA), occiput–C2 angle (Oc–C2A), clivusaxial angle (CAA), and C2–7 angle (C2–7A) were considered for quantitative reduction. Twelve patients with BI complicated with AAD received posterior interarticular release and individualized cage implantation to restore vertical dislocation. The POCA was adjusted using cantilever technology to further reduce the horizontal dislocation and adjust lower cervical vertebral angle. All patients received a radiological follow-up for ≥12 months. Improvements in spinal cord function were evaluated using Japanese Orthopedic Association (JOA) score. Results: All the patients received successful quantitative reduction for BI-AAD, and bony fusion was achieved without spinal cord injury after surgery for 12 months. The JOA score was improved significantly to 15.2 ± 0.9 twelve months after surgery (p < 0.01). Radiological follow-up revealed that individualized cage and POCA play vital roles in quantitative correction: (1) distance of the dens above McRae’s line and atlantodens interval were restored to normal level, respectively; (2) changes in Oc–C2 angle (ΔOc–C2A), C2–7 angle (ΔC2–7A), clivus-axial angle (ΔCAA), and POCA (ΔPOCA) were all caused by changes in axis tilt. Based on the changes of radiological parameter we deduced the formula for quantitative reduction by linear regression analysis: -ΔPOCA = ΔOc–C2A = -ΔC2–7A = ΔCAA. Conclusion: Quantitative posterior reduction by individualized cage and adjusting ΔPOCA is feasible for treating BI with AAD.

      • KCI등재

        Analysis of TRRAP as a Potential Molecular Marker and Therapeutic Target for Breast Cancer

        Ji Wang,Ming Shan,Tong Liu,Qingyu Shi,Zhenbin Zhong,Wei Wei,Da Pang 한국유방암학회 2016 Journal of breast cancer Vol.19 No.1

        Purpose: This study was designed to assess the protein levels of transformation/transcription domain-associated protein (TRRAP) in invasive ductal breast carcinomas, and investigated the association between TRRAP and the clinicopathological features of breast cancer. Methods: We examined TRRAP protein expression in 470 breast cancer tissues and normal breast tissues by tissue microarray to study the correlation between TRRAP expression and clinicopathological features. This was analyzed using the chi-square test. Kaplan-Meier survival curves and log-rank tests were applied to analyze the survival status. Cox regression was applied for multivariate analysis of prognosis. Results: The data demonstrated that expression of TRRAP was significantly lower in breast carcinomas (36.6%) than in corresponding normal breast tissues (50.8%). In addition, TRRAP protein levels negatively correlated with tumor size, and indicated poor differentiation, increased nodal involvement, and low p53-positive rates. Analysis of survival revealed that lower TRRAP expression correlated with shorter survival time. Univariate analyses identified TRRAP and progesterone receptor as independent protective factors for breast cancer prognosis. However, Ki-67, tumor size, and nodal involvement appeared to be independent risk factors. Conclusion: The findings indicate a significant correlation between TRRAP protein levels and adverse prognosis in breast cancer. Therefore, TRRAP could be a prognostic biomarker for breast cancer. In addition, TRRAP is also a predictive biomarker of breast cancer treatment.

      • KCI등재

        Methylation-associated silencing of BASP1 contributes to leukemogenesis in t(8;21) acute myeloid leukemia

        Lei Zhou,Lin Fu,Na Lv,Jing Liu,Yan Li,Xiaosu Chen,Qingyu Xu,Guofeng Chen,Baoxu Pang,Lili Wang,Yonghui Li,Xiaodong Zhang,Li Yu 생화학분자생물학회 2018 Experimental and molecular medicine Vol.50 No.-

        The AML1-ETO fusion protein (A/E), which results from the t(8;21) translocation, is considered to be a leukemiainitiating event. Identifying the mechanisms underlying the oncogenic activity of A/E remains a major challenge. In this study, we identified a specific down-regulation of brain acid-soluble protein 1 (BASP1) in t(8;21) acute myeloid leukemia (AML). A/E recognized AML1-binding sites and recruited DNA methyltransferase 3a (DNMT3a) to the BASP1 promoter sequence, which triggered DNA methylation-mediated silencing of BASP1. Ectopic expression of BASP1 inhibited proliferation and the colony-forming ability of A/E-positive AML cell lines and led to apoptosis and cell cycle arrest. The DNMT inhibitor decitabine up-regulated the expression of BASP1 in A/E-positive AML cell lines. In conclusion, our data suggest that BASP1 silencing via promoter methylation may be involved in A/E-mediated leukemogenesis and that BASP1 targeting may be an actionable therapeutic strategy in t(8;21) AML.

      • KCI등재

        MoO3 modified CeO2/TiO2 catalyst prepared by a single step sol–gel method for selective catalytic reduction of NO with NH3

        Ye Jiang,Zhimin Xing,Xuechong Wang,Shanbo Huang,Qingyu Liu,Jingshan Yang 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.29 No.-

        A MoO3 modified CeO2/TiO2 catalyst was prepared by a single step sol–gel method for selective catalyticreduction of NO with NH3. The experimental results indicates that MoO3 modified CeO2/TiO2 catalystexhibited higher SCR activity and resistance to 10% H2O and 1000 ppm SO2. From the characterizationresults, it can be concluded that good physical properties, highly dispersed active species of Ce and Mo,more appearance of Ce3+ and chemisorbed oxygen, strong interaction among ceria, molybdenum andtitania, and high oxygen storage capacity might contribute to the excellent deNOx performance of CeO2–MoO3/TiO2 catalyst prepared by a single step sol–gel method.

      • KCI등재

        Effects of different diets on the growth and development of young silkworms

        Wang Yuanfei,Shu Qilong,Gu Haoyi,Feng Piao,Dai Minli,Zhu Qingyu,Liu Wei,Dai Yan,Li Fanchi,Li Bing 한국응용곤충학회 2023 Journal of Asia-Pacific Entomology Vol.26 No.4

        To investigate the impact of different diets on the growth and development of the silkworm Bombyx mori (L.; Lepidoptera: Bombycidae), we conducted an analysis of differentially expressed genes (DEGs) between larvae fed an artificial diet (referred to as the AD group) and those fed mulberry leaves (referred to as the ML group) during the first, second, and third instars using RNA sequencing (RNA-Seq) technology. Our results revealed that the DEGs primarily belonged to pathways associated with lipid metabolism, carbohydrate metabolism, amino acid metabolism, the endocrine system, the nervous system, the digestive system, the immune system, and oxida tion–reduction processes. Notably, in the AD group, there was a decrease in transcript levels of genes related to amino acid metabolism synthases, while the transcript levels of antimicrobial peptide genes were up-regulated. Furthermore, genes associated with cytochrome P450 (CYP) enzymes exhibited down-regulation in the AD group. These observed changes likely contributed to the delayed growth and compromised robustness observed in the AD group. Overall, these findings provided valuable insights into the mechanisms underlying the differ ences in growth, development, disease resistance, and adversity resistance between silkworms fed an artificial diet and those fed mulberry leaves.

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