임플란트 보철물에서 임시 접착용 시멘트의 인장결합강도 비교

서경숙,권태엽,권용훈,김교한 大韓齒科器材學會 2003 대한치과재료학회지 Vol.30 No.4

The major disadvantage of cement-retained implant-supported superstructure is difficulty of retrievability. Sometimes, it is recommended that proetheses be provisionally cemented to implant abutment in order to ebaluate occlusion, screw loosening and tissue reaction. The retention of the provisional luting cementedusually employed in this case is considered to be important. This study compared tensile bond strength of gold crowns cemented to machined titanium implant abutments with three provisional luting cements. Also the effect of petrolatum and thermocycling on tensile bond stength were evaluated. Tensile bond strength of provisional luting cement were as follows with the decreasing order of Eugenol (13.06±1.544 kgf), Temp-Bond (9.41±0.737 kgf), Cavex (8.04±0.974 kgf), and Temp-bond with petrolatum (5.28±0.800 kgf). The addition of petrolatum in Temp-bond decreased tensile bond strength significantly (p<0.01). After thermocycling of 1,500 cycles, the tensile bond strengths of the cements were decreased with the order of Nogenol (10.87±3.031 kgf), Temp-Bond (8.1±0.667 kgf), Cavex (7.33±1.103 kgf), Temp-bond with petrolatum (4.88±1.348 kgf). The mocycling decreased the bond strength of Temp-Bond significantly, with no effects no other cements (p<0.01).

퇴행성 슬관절염에 대한 제통단의 안정성과 효능 임상연구

서병관,류성룡,강중원,안경애,이상훈,최도영,김건식,이두익,이윤호,이재동 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : In order to investigate the efficacy and safety of the newly developed herbal medicine Jetongdan, a placebo-controlled randomized clinical trial of patients with osteoarthriotis of the knee was undertaken. Methods : Data were obtained from 80 patients with OA of the knee. After the enrollment, they were asked to answer a disease-specific questionnaire (Western Ontario and McMaster Universities (WOMAC) OA index) and analyzed with the erythrocyte sedimentation rate (ESR) in order to evaluate the efficacy of Jetongdan, and analyzed for aspartate transaminase (AST) level, alanine transminase (ALT) level, blood urea mitrogen (BUN) level, and creatinine (Cr) level in order to evaluate the safety of Jetongdan. Results : The liver function and renal function did not deteriorate after treatment with Jetongdan. Composite WOMAC score and physical function subscale was improved, but pain subscale, stiffness subscale, and ESR were not improved by Jetongdan. This was possibly because the baseline characteristics of the two groups were not homogenized after randomization. Conclusions : Jetongdan could be a promising treatment option for osteoarthritis of the knee. Further study in a larger population with appropriate severity grades is recommended.

신발유형별 보행동작의 운동역학적 동작분석

서국웅,윤양진,김용재,이훈식,유경복 부산대학교 사범대학 1995 교사교육연구 Vol.30 No.-

The purpose of this study was to prepare some useful data for the prevention of injury caused by shoes when female was walking. Kinematic variables were analyzed with the aid of the visual materials filmed with a 16mm high speed camera, such as angular changes of joints, displacement, velocity, and momentum of the center of body gravity. The subjects for the research were normal 4 female high school students: The analytic results of the mechanism of each locomotion pattern were as follows: 1. It is desirable Kinematically that the dispersion of power should not be caused in the movement of lower-legs by keeping natural flexion and extension of joint. 2. Too much vertical displacement of the center of body gravity was thought undesirable because it caused the dispersion of power against the moving direction. To get some propulsion in the moving direction, it was efficient to use as much energy as possible from 8 F-F support phase to the toe-off. And also the center of body gravity was moved by the inertia just after toe-off. 3. The correct walking motion occurred when the walker moved their hip joint or knee joint gently with their upper body upright and their eyes looking around. 4. In order to lengthen the stride it was essential to practice intensively the flexion of the hip joint, extension of knee and plantar flexion of ankle joint. 5. It was proved that in race walking, they could get much greater propulsion from the flexion of the ankle joint than from the hip joint or the knee joint. It was, therefore, very important to train walkers so that the initial planter flexion of the ankle joint might occur from 6 F-F of the supporting phase. 6. The flexion of the ankle joint produced the added propulsion in the moving direction but the excessive flexion increased energy consumption and caused strain on the ankle joint because it dispersed power in moving the center of body gravity. 7. It was desirable to narrow the ankle of the flexion of the hip and knee joints because it could speed up revolutions per minute of the lower limb through lessening the inertia of the revolutions. The angle made by knee joint was desirable for getting the greatest propulsion in the moving direction. 8. High heel was lower than barefoot or jogging shoes in the displacement of the center of body gravity. This result showed that the displacement of the center of body gravity was made safe by lowering the flexion and extension of knee joint.

퇴행성 슬관절염 환자의 증상 중증도 지표와 DITI의 상관성 연구

서병관,류성룡,강중원,안경애,이재동,최도영,김건식,이두익,이윤호,이상훈 EAST-WEST MEDICAL RESEARCH INSTITUTE KYUNG HEE UNI 2005 東西醫學硏究所 論文集 Vol.2005 No.-

Objectives : To investigate the applicability of thermography as severity measurement in the patients with osteoarthritis (OA) of the knee. Methods : Data were obtained from 80 patiens with OA of the knee. They were asked to answer two disease-specific questionnaire (Western Ontario and McMaster Universities (WOMAC) OA index, Lequesne's Functional Index (LFI)), one generic instrument (Korean Health Assessment Questionnaire (KHAQ)), VAS in order to assess the severity of disease, quality of life, degree of pain and taken thermography in standardized environment. Results : The thermal difference between ipsilateral side and contralaterla side of lateral aspect of knee was correlated with that of medial aspect of knee, and the thermal difference of anterior thigh was correlated with that of lateral, medial aspect of knee and patella region. Age, duration of disease, duration of morning stiffness, sex, crepitus, and painful side of knee were not correlated with the thermal differences of each region. LFI, WOMAC, WOMAC pain subscale, WOMAC stiffness subscale, WOMAC physical function, KHAQ,, VAS were not correlated with the thermal differences of each region. Conclusion : Further study on the thermography on OA of the knee in population with appropriate severity grade and the standardization of analysis of thermographic data were recommended.

정상 교합자와 하악 전돌증 환자에서 panorama상의 하악공의 위치에 대한 비교 연구

서병서,이재훈,김경욱 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.3

Due to lack of knowledge in location of the mandibular foramen, it's occasionally occurred the anesthetic failure or the injury of mandibular nerve and vessel during surgery. We took a test setting the mandibular prognathism patient(experimental group, 50 persons) against the patient with normal occlusion(control group, 50 persons) to prevent these problems and to grasp the location change of mandibular foramen according to facial profile. After measuring and comparing the location of mandibular foramen, using panoramic radiographs, we came to following conclusion. There wasn't significance in the antero-posterior location of mandibular foramen between control and experimental group(p>0.05). There was considerable difference in the upper and lower position of mandibular foramen between control and experimental group. It appeared that the distnace of mandibular foramen from mandibular notch is 20.66㎜(average) for the normal occlusion and 17.785㎜(average) for the mandibular prognathism. So we can see the distance of mandibular foramen from mandibular notch for patients is more near 2.815㎜(average) than normals. For the distance of mandibular foramen from the extension line of occlusal plane, it's 0.92㎜(average) lower than occlusal plane for the normal and 0.5㎜(average) upper for the patient. It's located 1.42㎜(average) upper part of the patient.

같은 엽에 동시 발생한 갑상선 유두상암과 여포상암 2예

서경원,최재영,김정훈 고신대학교의과대학 2008 고신대학교 의과대학 학술지 Vol.23 No.4

We report two rare cases of concurrent papillary thyroid carcinoma and follicular thyroid carcinoma on the same lobes of the thyroid gland. A 35-year-old female and a 32-year old male presented with a one-week history of throat discomfort and palpable anterior neck mass on the same lobe, respectively. Fine needle aspiration biopsy of two nodules resulted in papillary thyroid cancer and follicular neoplasm. This patients underwent total thyroidectomy and central compartment neck dissection. The pathologic diagnosis of two nodules at Rt. lobe of thyroid was papillary carcinoma(PTC) and follicular carcinoma.

유두에 발생한 음부 평활근종 1예

계경채,이영,서영준,이증훈,박장규,김진만,김협 대한피부과학회 2006 大韓皮膚科學會誌 Vol.44 No.4

심혈관계질환으로 사망한 성인형다낭신 3예 보고

양경무,권일훈,조갑래,서중석 大韓法醫學會 1999 대한법의학회지 Vol.23 No.1

Adult polycystic kidney disease is a genetic disease characterized by bilateral multiple renal cysts and is transmitted as an autosomal dominant traits. The disease usually manifests in the fourth decade of life. The affected patients usually die with end stage renal failure, cardiovascular assaults and infection etc. Cardiovascular assaults include ruptured berry aneurysm, spontaneous intracranial hemorrhage, acute myocardial infarction, dissecting aortic aneurysm and hypertensive heart failure. Fatal intracranial hemorrhage and hypertensive heart failure occur in 15% and 2% of patients, respectively. Genetically-dater-mined structural weakness in the arterial wall have been suggested as a possible factor in the genesis of berry aneurysm. We have experienced three autopsy cases with cardiovascular causes of sudden death. Two cases have intracranial hemorrahage (1 berry aneurysm and 1 intracerebral hemorrhage) and the remaining one is dead with hypertensive cardiomyopathy. All of them are aged over 40 years and associated with polycystic liver disease. Histologically, myriad cysts of enlarged bilateral kidney are lined by single layer of cuboidal cells with focal hyperplastic epithelial configuration. Diffusely scattered liver cysts are also lined by flat to cuboidal epithelium and often associated with portal fibrosis.

대학 교직원의 라이프스타일에 따른 세분시장별 대학 교직원 급식소 서비스 품질 인식 분석

박문경,양일선,김동훈,신서영,이해영 대한지역사회영양학회 2003 대한지역사회영양학회지 Vol.8 No.4

Market segmentation helps providers to find better marketing opportunities and allows foodservice managers to develop the right product for each target market. Therefore, this study, taking university faculty and staff as subject, is intended to diagnose the relative value of service quality attribute, on the basis service quality scenario of faculty foodservice to suggest price for improving customer loyalty in market segments. A questionnaire was developed and mailed to 600 Yonsei university faculty and staffs. A total of 385 questionnaires were usable; resulting in a 58.7% of faculty and a 69.7% of staff response rate, respectively. Statistical data analysis was completed using the SAS/Win 6.12 for descriptive Analysis, ANOVA, principal factor analysis, cluster analysis, reliability test and discriminant analysis. The results of the study are as below. Eighteen questions were selected for measuring respondents' lifestyle by AIO method and the seven lifestyle factors derived from factor analysis and aggregated distinct 4 clusters. Service quality attributes of the scenario were determined with 'food quality', 'menu variety', 'atmosphere', 'fast service', and 'clean and sanitation'. 'food quality', 'menu variety', 'atmosphere', 'fast service', and 'clean and sanitation', in decreasing order, were identified as improving customer loyalty. However, most faculty and staffs were satisfied with the present meal price. The result of this study indicates that the relative value of service quality was differed significantly among the various market segments. 'Food quality', 'menu variety', and 'atmosphere' were determined as major service quality attributes. Thus, customer loyalty could be increased by improving food taste and quality, atmosphere, and service delivery.

정상 성인에 경구 투여한 Cefixime 두 정제의 생물학적 동등성 비교

강진양,서성훈,이경태,문창훈,강진한,이동건,최정현,신완식 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.4

목적 : 식품의약안전청 고시 제 1998-86호(1998. 8.26) "생물학적 동등성 시험 기준"에 의하여 섹심 캅셀(시험약, 한국유나이트제약)과 슈프락스 캅셀(대조약, 동아제약)의 생물학적 동등성을 비교 검토하였다. 방법 : 2×2 라틴 방격법에 따라 건강한 성인 남성 지원자 20명에게 cefixime 100㎎씩 경구투여하였다. 약제투여 후 12시간까지 일정간격으로 채혈하였고 각 피험자들의 혈중약물농도 데이터로부터 구한 Area under the concentration (AUC), C_(max), T_(max) 등의 생체이용률 파라미터에 대해 통계학적으로 고찰하여 두 제제간의 생물학적 동등성을 평가하였다. 결과 : AUC, C_(max), T_(max)에 대한 평균값의 차가 각각 1.26%, 3.73%, 6.21%로서 모두 대조약의 20% 이내에 들어 생물학적 동등성 판정기준의 전제조건을 만족하였다. 분산분석 결과 AUC, C_(max), T_(max)의 각 비교 항목에 있어서 모두 유의수준 α=0.05의 군/순서효과 검정에서 F비가 F 분석표의 한계값보다 작아 교차시험이 제대로 이루어졌음을 확인할 수 있었으며, AUC, C_(max), T_(max) 각 비교항목에 있어서 유의수준 α=0.05에서 대조약에 대한 최소검출차(Δ)가 각각 17.74%, 17.05%, 15.67%로 모두 20% 이내이었으며, 검출력(1-β)도 모두 0.8 이상으로 나타나 생물학적 동등성 판정기준을 만족시켰다. 또 AUC, C_(max), T_(max) 각 비교항목에 있어서 대조약에 대한 생체이용률 차이의 신뢰한계(δ)가 ±20% 이내이어야 한다는 생물학적 동등성 판정기준을 모두 만족시켰다. 결론 : 이상의 실험결과로 시험약은 대조약에 대하여 생물학적 동등성 평가항목인 AUC, C_(max), T_(max)에서 모두 판정기준을 만족시켜 시험약은 대조약과 생물학적으로 동등하다고 사료된다. Background : The study was designed to compare the bioeqivalence between the test (CEXIME®. United Korea. Co., Ltd) and control (SUPRAX®. Dong-a Pharm. Co.. Ltd) capsules of cefixime. Methods : Twenty. healthy, male volunteers completed the study Each subject ingested single dose (100 ㎍) of the control and test drugs in 2?2 crossover design with a week drug-free interval between the doses. Blood samples were collected serially up to 12 hours and plasma concentrations of cefixime were measured by high-performance liquid chromatography with UV detection. A non-compartmental approach was used for analysis of the concentration-time data. Results : The area under the curve (AUC), the maximum concentration of drug (C_(max)). and time to reach C_(max)(T_(max)) did not show any significant difference between the two preparations by ANOVA. The mean differences of AUC, C_(max), and T_(max) were within 20% of the control drug, those were 1.26%. 3.73%. and 6.21%. respectively. The confidence limits of three parameters were satisfied the bioeqivalence criteria. Conclusion : These results suggest that the test drug was bioequivalent with the control drug.