건축공사시방서에서의 KS규격의 국제인증방안에 관한 연구

김경식,이재섭,김용수,이규진,조용훈,최완철,전재열,이현수,구재동,이기환 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

The purpose of this research is make out construction specifications for International Construction. Using off-shore products incur cost increase and longer delivery term of construction. and inconvenient on International Construction. Expand the range of additional local products conforming to performance. Life Cycle Cost. maintainability. operability. user's acceptability, etc.. And this study is suggest the standard formats and the techniques for construction specification.

Slide Session : OS-IFD-07 ; Infectious Disease : In Vitro Antiviral Activity of Ribavirin Against Severe Fever with Thrombocytopenia Syndrome Virus

( Myung Jin Lee ),( Kye Hyung Kim ),( Jong Youn Yi ),( Su Jin Choi ),( Chung Jong Kim ),( Nak Hyun Kim ),( Kyoung Ho Song ),( Pyoeng Gyun Choi ),( Ji Hwan Bang ),( Wan Beom Park ),( Eu Suk Kim ),( San 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

In Vitro Antiviral Activity of Ribavirin Against Severe Fever with Thrombocytopenia Syndrome Virus Myung Jin LEE1, Kye-Hyung KIM1, Jongyoun YI2, SuJin CHOI1, Chung-Jong KIM1, Nak- Hyun KIM1, Kyoung-Ho SONG1, Pyoeng Gyun CHOI1, Ji-Hwan BANG1, Wan Beom PARK1, Eu Suk KIM1, Sang-Won PARK1, Hong Bin KIM1, Nam Joong KIM1, Myoung- Don OH1 Seoul National University College of Medicine, Korea1, Pusan National University School of Medicine, Korea2 Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel Bunyavirus, severe fever with thrombocytopenia syndrome virus (SFTSV). No effective antiviral therapy is proven yet, but clinical use of ribavirin (RBV) has been tried. We investigated the antiviral effect of RBV against SFTSV in vitro. Methods: To test for cytotoxicity of RBV, Vero cells were treated with different concentrations of RBV (3.90 to 500 μg/mL, two-fold dilution) and analyzed by cell viability MTS assay 48h post-infection. To determine antiviral activity of RBV against SFTSV, Vero cells were infected with SFTSV strain Gangwon/Korea/2012 at 100 TCID50 (50% tissue culture infective dose) per well in a 96-well plate, and RBV was added at the concentrations showing no or minimal cytotoxicity. Viral RNAs were extracted from the culture supernatants and quantifi ed using one-step real-time reverse transcription- PCR to amplify the partial large segment of SFTSV. Statistical analysis was done by one-way ANOVA with Tukey`s post hoc test. Results: Cytotoxicity due to RBV was not observed at RBV concentration =31.3 μg/ mL. Viral RNAs at 24h post-RBV treatment were reduced with increasing RBV concentrations (1-32 μg/mL), compared with those of mock-treated cells (P <0.01, Figure). Half maximal inhibitory concentration (IC50) of RBV was 3.69 μg/mL at 24h post-RBV treatment. Conclusions: Our study shows that RBV has antiviral effect against SFTSV in a dose-dependent manner. Further studies are required to evaluate the effi cacy of RBV in SFTS.

Carbosulfan의 피부자극성, 안점막 자극성 및 피부감작성등의 알러지성 효과에 관한 연구

이상훈,이동연,백경진,김태원,정두순,임종환,김명석,박병권,윤효인 충남대학교 수의과대학 동물의과학연구소 2004 動物醫科學硏究誌 Vol.12 No.-

Many studies have been published on the human health effects of carbosulfan toxicity. Carbosulfan used as an insecticide can produce an irritating and allergenic effect when acting on the skin. In this study, a sensitization test on albino guinea pigs and intradermal reactivity and occular irritation test on albino rabbits were carried out with carbosulfan. Signs of acute skin inflammation appeared along with the clinical symptom of chronic dermatosis caused by the solution irritating characteristics. Moreover, carbosulfan showed severe eye irritation with conjuctival redness and severe opacity on cornea. Preventive measures should involve workers' obligatory instructions on the noxious impact on human skin and strict observance of industrial safety rules.

정전 열 접합을 이용한 Multi-Substrate Bonding

이덕중,주병권,최우범,한정인,조경익,이광배,장진,오명환 경북대학교 센서기술연구소 1997 센서技術學術大會論文集 Vol.8 No.1

We performed silicon-to-glass bonding using silicon direct bonding followed by anodic bonding(SDAB). Initial bonding between glass and silicon was caused by the hydrophilic surfaces of silicon and glass ensemble using silicon direct bonding(SDB) method. We found that the bonded specimen using SDAB process had higher strength than one using anodic bonding process only. We performed multiple layer bonding by SDAB, which is glass- silicon -glass as sandwich structure. In the silicon wafer, the (1mm x 2mm x 500μm)-sized cavity was formed by the anisotropic etching of the silicon substrate in EPW(Ethylendiamin-Pyrocatechol-Water). And, the cavity was sealed with glass wafers by SDAB method.

정보통신 표준화 지수측정 모형 개발 연구

이승환,박명철,이상우,구경철 한국경영과학회 2003 經營 科學 Vol.20 No.2

The standard issue in the information and telecommunication industry is increasingly important with the rapid development of technology. This paper proposes an index model which can measure the degree of standardrzation in the Korean information and telecommunication field We first classified ICT sector into 14 sub-sectors. Then for each sub-sector, we considered a Set of important determinants to measure the level of standardization, and constructed a linear equation using this set of determinants Finally we estimated the relative degree of importance of each determinant using the AHP methodology The proposed model found that overall level of standardization In the Korean ICT industry is relatively low, and "IMT-2000 technology" and "computer network technology" among 14 sub-sectors are highly standardized sub-sectors The validity of the proposed model was also partially proved using two different methods, holistic and historical approach.

다품종 조립라인의 Web기반 일정계획 소프트웨어 개발

이경진,이정환,이승훈 동의대학교 산업기술개발연구소 2005 産業技術硏究誌 Vol.19 No.-

To cope with corporation environments such as global economy era, increased product diversity and rapid market environmental change, the production system should be operated with capabilities to supply products in time and the lowest price that meet customer's demands. Therefore, the production system has been changed from mass production system of conveyor type to U-line system based on JIT according to market environmental change. Scheduling on the production activities is to decide proper time and methods for each activity by supplying materials within limited time. If the scheduling, however, is not favorable, it will not only fail to meet appropriate supplying time but also cause inefficiency caused by the low utilization of diverse elements for production activities. Therefore, the study is to understand characteristics of U-line and look over the theoretical background of scheduling planning. This application was developed by using Visual basic 6.0 and Active X control.

회생용 4분할 2상 쵸퍼에 의한 회생영역의 확대

이승환,김용주,한경희,정연택,강승욱 明知大學校 産業技術硏究所 1993 産業技術硏究所論文集 Vol.12 No.-

In this paper, we proposes two phase chopper system with flour. separate groups of D.C motor for regenerative braking. The main circuit consists of four sets of chopping parts, eight diodes and four separate groups of D.C motor. Although the proposed chopper circuit requires more circuit elements than the conventional two phase chopper system with, combined output, it has the following advantages: (1) The region of regenerative braking becomes twice as that of the conventional two phase chopper system. (2)Current division of load becomes equalized. Therefore. it is possible to drive not only series motor but also shunt and separately excited motor (3) The harmonic component of the source current is greatly diminished.

긴 인식 거리를 가진 후엽이 없는 Yagi-Uda형태의 UHF RFID Tag 안테나

이경환,정유정 대구대학교 정보통신연구소 2006 情報通信硏究 Vol.4 No.1

통풍 환자에서의 지질대사

이은우,강기서,강수용,이한준,김경환,임정일,박철경 중앙대학교 의과대학 의과학연구소 2001 中央醫大誌 Vol.26 No.2

Objective: To evaluate hyperlipidemia, a msjor tisk factor of coronary artery disease, frequently asscoiated with gout patients, we compared the mean lipid level of gout patient with that of non-gout male and accessed statistical significance for treatment of gout patient. Method: This study ws performed in the 266 male gout outpatients of the CAU medical center, who had serum lipid level test from Apr. 1996 to Aug. 2000. Serum uric acid, total cholesterol, triglyceride, HDL -cholesterol, and LDL-cholesterol level were measured after 12 hours of fasting. The patients with high lipid level were further evaluated into each type of the hyperlipidemia through electrophoresis study, and the test results were compared with that of the non-gout male adults(40∼60yr), and the statistical significance was examined. Results : The gout patients showed high levels of total cholesterol, triglyceride, and LDL-cholesterol. Especially they showed high level of triglyceride and LDL-cholesterol which suggested as the risk factors of atherosclerosis and coronary heart disease, but shoewed low level of HDL -cholesterol. But there were no definite relations between lipid level and other factors auch as age of patient, initial uric acid ;eve; and duration od gout. Conclusion: To evaluate the risk factors of atherosclerotic change of cadriac vascular system in gout patient, screening tests of serum lipid level of the patient seem mandatory.

조구등(釣鉤藤)의 4-VO로 유발한 흰쥐뇌허혈에 대한 신경방어효과

李仁煥,林康鉉,李鍾錫,石庚浩,安德均,朴虎君,김頀哲 대한본초학회 1999 大韓本草學會誌 Vol.14 No.2

Uncariae Ramulus et Uncus(UR, ???) has sweet in flavour and slightly cold in property, acting on the liver and pericardium channels. This drug was described in a medical classic as having the ability to remove "heat", check hyperfunction of the liver and relieve dizziness, tremors, and convulsion, and subdue "endogenous wind". So this study was planned to check the neuroprotective effect of UR on the global ischemia induced by 4-vessel occlusion in Wistar rats. and UR extract was lyophilized after extraction with 70% methanol. We induced 4-vessel occlusion for 10 minutes and reperfused again. The number of CA1 pyramidal neurons were counted after 7 days of reperfusion under the cresyl violet staining. In 4-VO ischemia model, UR showed significantly neuroprotective effects(1,000 and 500 ㎎/㎏ of UR extracts, p<0.05) compared with control group. Each neuroprotective ratio was about 23.0%, 19.0% respectively. Consequently, Uncariae Ramulus et Uncus has neuroprotective effects on the global ischermia induced by 4-vessel occlusion in Wistar rats. So we expect that Uncariae Ramulus et Uncus can be used as a drug for neurodegenerative disease.