뇌동맥류 환자의 임상분석

강삼석,박중욱,류재광,신동철,김봉환 全南大醫大 1983 전남의대학술지 Vol.20 No.1

대장암환자에서 자연살해세포의 변화

김광호,심강섭,박응범,강은숙,홍기숙 대한대장항문학회 1998 Annals of Coloproctolgy Vol.14 No.3

일부 소방공무원의 음주와 직무스트레스와의 관련성

강경화,이강숙,김석일,맹광호,홍현숙,정춘화 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

목적 : 소방공무원의 음주량과 직종별 직무 스트레스에 대해 알아보고 보다 나은 스트레스 관리방안과 문제성 음주예방을 위한 프로그램을 모색하기 위해 시도되었다. 대상 : 2000년 7월부터 8월까지 소방공무원 중 구조대원 97명, 구급대원 97명, 화재진압대원 179명,행정대원 116명, 기타대원 49명을 대상으로 설문지를 이용하여 수집된 자료를 분석하였다. 결과 : 소방공무원은 모든 직종에서 승진 및 임금제도의 스트레스 요인 점수가 가장 높았다. 직종별로 직무 내적 요인, 조직에서의 역할, 대인관계, 조직과 풍토, 직장환경과 스트레스 결과 점수에 있어 유의한 차이를 보였다 과음 주자인 경우 직무 내적요인, 직무 스트레스 수준, 개인적 특성, 대처방식의 점수가 높았으나 유의하지 알았다. 음주량은 직무내적 요인 중 업무 피드백과 음의 관련성을, 직무 스트레스 요인 중 역할 갈등은 음주량을 증가시키는 것으로 나타났다. 결론 소방공무원의 가장 높은 직무 스트레스 요인으로는 승진 및 임금제도인 것으로 나타났다. 음주량은 역할 갈등과 같은 직무 스트레스 요인과 관련이 있었으며, 향후 전향적인 음주행태조사를 통해 직무 스트레스 요인이 음주에 미치는 영향을 파악하기 위한 연구가 필요하다고 생각된다. 따라서 본 연구결과를 기초로 소방공무원의 직무 스트레스 요인에 대한 적절한 관리와 정책이 필요한 것으로 사료된다. Objectives : To establish the relationship between alcohol use and job stress among firemen, and to develop a comprehensive health promotion program including stress management and the prevention of problem drinking. Methods : Data was collected from July to August, 2000. Study subjects included 97 rescue workers, 97 emergency medical personnel, 179 fire extinguishers, 116 administrators and 49 others. Results : The firemen displayed higher scores of stress due to promotion-related pres-sures and salary. We found significant differences in job internal factors, job role, inter-personal relationship, organizational norm, work environment and stress outcome among the various jobs. Job internal factors, job stress factors, personal characteristics, coping skills, and stress outcome were higher in heavy drinkers compared with the light and moderate drinkers. Job internal factors and smoking habit showed a positive correlation with the amount of drinking, although coping skill, exercise frequency and monthly income showed a negative relation with the amount consumed. Conclusion : This study suggested that alcohol drinking is associated with job stress. This suggests that a comprehensive health promotion program including stress management and problem drinking prevention and control should be developed.

Polytetrafluoroethylene의 길이에 따른 신생내피의 조직학적 변화에 대한 실험적 연구

강기훈,이광석 고려대학교 의과대학 1998 고려대 의대 잡지 Vol.35 No.2

One of the most widely used synthetic grafts in vascular surgery is polytetrafluoroethylene(PTFE). PTFE offers major advantages compared with the other synthetic materials because of its highly electronegative and hydrophobic surface. Neoendothelialization of PTFE is still the most controversial issue and seems to prevent its reliable clinical use in microvascular grafting procedures. It is difficult to compare different studies because of variations in the physical characteristics of synthetic grafts and the investigation periods. The purpose of this study was to investigate the patency rates and the histologic findings of neoendothelialization according to the length of implanted PTFE in rabbit. Thirty New Zealand White rabbits, weighing 3.0 to 3.5kg, were used for this study. Under the operating microscope, all grafts were implanted in the right carotid arteries of rabbits by interrupted end-to-end microanastomosis. They were divided into two groups according to the length of implanted PTFE with an internal diameter of 3mm. Each group comprised fifteen rabbits. All implanted grafts were 25㎛ in fibril length and 0.39mm in wall thickness. The length of graft in group Ⅰ was 8mm and that of graft in group Ⅱ was 24mm. Three grafts per group were harvested at 1, 2, 4, 8, and 12 weeks after implantation respectively. All PTFE grafts were observed for patency rates and the histologic findings with light microscope and scanning electron microscope. The results obtained were as follows : 1. The patency rate was 96.7%(29/30) on the average: 93.3%(14/15) in group Ⅰ and 100%(15/15) in group Ⅱ. There was no difference in patency rates according to the length of implanted PTFE. 2. Light microscopically, the beginning of neointimal lining was noted in both groups at 1 week after implantation. At 8 weeks after implantation, the entire inner surface of implanted PTFE was lined completely by neointima in both groups. At 12 weeks after implantation, neointima and subintimal tissue were noted at the midportion of implanted PTFE in group Ⅰ. However, neointima of group Ⅱ in the midportion of implanted PTFE was composed of single layered neoendothelial cells without subintimal tissue. 3. Scanning electron microscopically. the inner surface of implanted PTFE was lined by amorphous fibrin layer at anastomosis site in both groups at 1 week after implantation. At 2 weeks after implantation, flat irregular layer like normal endothelium was noted at anastomosis site in both groups. At 8 weeks after implantation, the entire inner surface of implanted PTFE was lined by neointima in both groups. At 12 weeks after implantation, closely apposed endothelial-like cells were noted in the mid-portion of implanted PTFE in group Ⅰ, the long axis of neoendothelial cells was parallel to the direction of the blood flow, but the inner surface of implanted PTFE was still noted in group Ⅱ. In conclusion, there was no difference in patency rates according to the length of implanted PTFE, and at 1 week after implantation neoendothelium started to grow from both anastomosis sites toward the center of implanted PTFE in both groups; however, the formation of neointima and subintimal tissue was delayed and incomplete in longer implanted PTFE. In the future, further study must be performed to accelerate the neoendothelialization after implantation of PTFE for the clinical use in microvascular surgery.

제2종 중도절단에 근거한 지수분포의 신뢰함수 추정

강석복,서영수,이광호 嶺南大學校 基礎科學硏究所 1997 基礎科學硏究 Vol.17 No.-

In this paper, we shall propose several reliability estimators in the two-parameter exponential distribution, and compare the proposed estimators in terms of the MSE through the Monte Carlo simulation.

방광 크롬친화세포종과 동반된 배뇨후 벼락두통

하윤석,강성진,허소영,이지현,김민정,김종국,김광수 고신대학교 의과대학 2009 고신대학교 의과대학 학술지 Vol.24 No.1

Thunderclap headache is a hyperacute, severe headache that is so named because the pain strikes suddenly and severely, and is sometimes a sign of a medical emergency. We report a case of pheochromocytoma in the urinary bladder in a 48-year-old woman who presented with recurrent thunderclap headache after voiding and exercise. So we think thunderclap headache during or immediately after micturition may be an important diagnostic clue of bladder pheochromocytoma.

내시경적 점막절제술로 치험한 식도 과립상 세포종 1례

강혁주,김성욱,최석진,이중현,장재식,서영범,윤병구,박건욱,김성자,김용섭,강승완,이구,양창헌,이창우,김욱년,이광헌,서정일 동국대학교 의학연구소 2000 東國醫學 Vol.7 No.-

과립상 세포종은 Schwann 세포 기원으로 생각되며 인체에 비교적 드물게 발생한다. 과립상 세포종은 전신 어느 곳에서나 발견될 수 있으나 주로 혀, 구강, 피부 혹은 유방 등에서 호발하며 드물게 위장관에서 발견된다. 위장관에서는 식도에서 가장 호발하며 다음으로 위, 대장 순이다. 과립상 세포종은 대부분, 특히 위장관에서는 양성이며 소수의 악성 병변이 보고되었다. 이러한 이유와 함께 수술 전의 진단이 어렵기 때문에 과립상 세포종에 대한 근본적인 치료는 현재까지 외과적 절제술이다. 최근에 시도되는 치료방법들로는 내시경적 레이저 치료, 용종절제술, 내시경적 점막 절제술 등이 있다. 저자들은 상부 소화관 내시경검사를 시행하여 식도 과립상 세포종을 진단하고 내시경적 점막 절제술을 시행하여 합병증 없이 퇴원하여 현재 재발없이 경과 관찰중인 1례를 경험하였기에 보고하는 바이다. Granular cell tumors, which occur infrequently, are probably of Schwann cell origin. They can occur almost anywhere in the body but usually affect the tongue, oral cavity, skin, or breasts and are rarely found in the gastrointestinal tracts. The esophagus is the most frequent gastrointestinal site, followed by the stomach and the colon. Granular cell tumors are generally benign, especially in the gastrointestinal tract, some malignant lesions have been reported. For this reason, and also because preoperative diagnosis is difficult, the standard treatment for granular cell tumor has until now been surgical excision. In recent years, other therapeutic methods is endoscopic laser therapy (ELT), polypectiomy, endoscopic mucosal resection (EMR). We report a case of esophageal granular cell tumor which was diagnosed by an endoscopy and managed using an endoscopic mucosal resection without complication.

일 대학 병원 마취 · 회복실 간호사의 간호활동 분석

강윤경,김경미,김연이,박혜옥,서광희,송숙녀,이현숙,조의영 대한간호행정학회 2006 간호행정학회지 Vol.12 No.1

Purpose: This study was aimed to specify roles of nurses from the anesthesia and recovery room by analyzing nursing activities as well as anesthesia nursing during surgery. Method: The objects were 12 RNs working in the recovery room of a university hospital located in Incheon. Self-report was performed by measuring stop-watch for five days from May 17th to May 21st in 2004. Research method was designed to record the time and frequency of the nursing activity from anesthesia and recovery room based on nurses' statement and other references for five days. The data were analyzed with descriptive statistics, ANOVA, and t-test via SPSS Win 10.0 program. Result: Nursing activities in anesthesia recovery room were classified into two different characteristics such as direct and indirect nursing activity. The activities consisted of 11 direct nursing areas and 39 nursing activities in anesthesia preparation room. The indirect nursing was classified into 8 nursing areas and 32 nursing activities. The direct nursing was classified into 12 nursing areas and 55 nursing activity. Also, the indirect nursing was classified into 7 nursing areas and 21 nursing activities in recovery room. In terms of prevalence of nursing activities in the anesthesia preparation room, observation and cooperation of anesthesia was the most prevalent activity, drug and eqipment management the second prevalent, and drug administration the third. On the other hand, in the recovery room, the most prevalent activity was vital sign checking and observation, the second most prevalent activity informative activity, and the third body temperature control. Nursing activity time was recorded according to the nursing characteristics. In the anesthesia preparation room, the direct nursing spent for 8092.20 minutes was larger than the indirect nursing spent for 7198.50 minutes. Also, in the recovery room, the direct nursing spent for 2361.16 minutes was larger than the indirect nursing spent for 1134.13 minutes. 4. Nursing activity time was compared to duty shifts. In the anesthesia preparation room, the direct nursing was more prevalent on day shift and the indirect nursing was prevalent on evening shift. However, in the recovery room, both direct and indirect nursing activities were prevalent on day shift. Conclusion: The role of anesthesia and recovery room nurses was analysed according to the time, frequency, and its characteristics.

유기인제 중독 및 후유증 ; 지연성 다발성말초신경병증을 중심으로

강석윤,김광국 대한신경과학회 1999 대한신경과학회지 Vol.17 No.2

말초혈액 단핵구와 단핵구 유래 세포주 THP1에서 FcrR 자극에 의해 유도되는 염증반응의 조절기전

윤강순,윤석란,이충은,김형순,변광호 大韓免疫學會 1993 大韓免疫學會誌 Vol.15 No.-

Regulation mechanisms of inflammatory responses induced by FcrR stimulation in human monocytes and monocytic cell line THP1 were investigated. Release of arachidonic acid, which is the precusor for inflammatory mediators, was induced by FcrR stimulation with its ligand human IgG or with anti FcrR mAbs. This response was further increased when FcrR was cross-linked with in-soluble anti-IgG-agarose and soluble anti-IgG Fc specific Fab fragments. These phenomena were shown in both monocyte and THP1. Oxidative burst activity, resulting from generation of reactive oxygen speices, was also induced by FcrR stimulation and further enhanced by cross-linking of Fcr R. Induction mechanisms of inflammatory responses caused by PMA or FcrR stimulations were then examined by measurements of release of arachidonic acid and oxidative burst activity. The results demonstrate that monocytes utilize different signaling pathways for FcrR or PMA stimulation. Signaling mechanism of PMA stimulation is especially dependent on Ca}+/calmodulin dependent kinase in arachidonic acid release, but not in oxidative burst activity. Meanwhile, signaling pathways of FcrR are dependent on tyrosine kinase but independent of protein kinase C both in the release of arachidonic acid and oxidative burst activity. The results suggest that in monocytes, there is a not only functional but also mechanistic link between arachidonic acid release and oxidative burst activity induced upon FcrR stimulation. Distinct signaling pathways seem to be operating in transformed monocytic cell line THP-1 cells, and no mechanistic link was found between arachidonic acid release and oxidative burst activity induced after FcrR stimulation.