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고나트륨혈증후 발생한 중심성 뇌교및 외뇌교 수초 용해증 1예
신현길,성기범,오건세,안무영 순천향대학교 1994 논문집 Vol.17 No.2
중심성 뇌교 수초 용해증은 일반적으로 심한 기저질환을 지닌 환자에서 심한 저나트륨혈증이나 저나트륨혈증을 급속 교정후 오는 것으로 알려져 있다. 저자들은 최근 만성 주정중독환자에서 심한 고나트륨혈증을 서서히 교정후 발생한 중심성 뇌교 및 외뇌교 수초 용해증을 뇌 자기공명 전산화 단층촬영으로 확진하였다. 심한 기저 질환을 가진 환자에서 장기간의 고나트륨혈증의 경우도 중심성 뇌교 수초 용해증을 일으킬 수 있기 때문에 이런 환자에서 저나트륨혈증뿐 아니라 고나트륨혈증도 피해야 될 것으로 사료된다.
朴吉俊,李東鍵 東亞大學校 附設 스포츠科學硏究所 1993 스포츠科學硏究論文集 Vol.11 No.-
The purpose of this study is on searching out the medical gymmastics of ancient chienese. The major point considered in the thesis follow ; 1. The process of formation in the medical gymnastics of ancient chinese has been formed by Taoist school as a means of the secret of long life. 2. The aspect of development in the medical gymmastics of ancient chinese gas been developed the art of「To-In」with the history of 5000 year. This is named 「Gi-Gang」in the present-day. 3. The medical gymnastics of taegae Lee in Korean philosophy of human nature and natural laws turn out「Pal-Dan-Kumd」in the medical gymnastics of ancient chinese.
유남재,전상현,정길수,김동건 강원대학교 산업기술연구소 2006 産業技術硏究 Vol.26 No.B
A probabilistic analysis model, one of reliability analysis methods introducing the concept of probabilistic variables, was developed to investigate the uncertainty of dominant factors influencing the degree of consolidation in the radial consolidation theories. Based on the developed probabilistic analysis model, sensitivity study of those factors was performed to find their trends of affecting the degree of consolidation in the vertical drain method. Various radial consolidation theories, Proposed by Barron(1948), Hansbo(1979), Yoshikuni(1979) and 0noue(1988), were used for this parametric study with the influencing factors such as size of smear zone, reduction ratio of permeability in the smear zone, discharge capacity, permeability for horizontal flow and coefficient of consolidation for horizontal flow. As results of this sensitivity study, for the given consolidation theory, contribution of each factor to the degree of consolidation was figure out and compared to each other. For the given value of each factor, the sensitivity to the degree of consolidation in the various theories was evaluated and their applicability and limitations were assessed.
A Review of Discarded Organs from Deceased Donors in South Korea
( Kil Hwan Kim ),( Youngrok Choi ),( Ho-seong Han ),( Yoo-seok Yoon ),( Jai Young Cho ),( Sungho Kim ),( In Gun Hyun ),( Won Hyun Cho ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1
Aims: Despite a steady increase in the number of organ transplantations performed each year throughout the world, the shortage of available organs for transplantation is worsening. This study aims to analyze the current status of discarded organs (Harvested, but not be transplanted organ) from deceased donors in Korea. Methods: We used KODA (Korea Organ Donation Agency) and KONOS (Korean Network for Organ Sharing) database to search for deceased donor organ transplantations (DDOTs) performed between 2013 and 2016. Based on the data, we analyzed the incidence and causes of discarded organs according to organs. Results: In South Korea, 6315 DDOTs were performed between 2013 and 2016. A total of 63 discarded organs were procured. The most common organ was the kidney (n=24) followed by islet cell (n=23), lung (n=9), liver (n=6) and pancreas (n=1). There were no discarded hearts. Except for islet cells, the most common reasons for organs to be discarded were organ dysfunction and vascular defects. All of discarded islet cells (n=23) were caused by separation failure or shortage of proper cell number. We also analyzed cases of discontinuation of harvesting operations for past 4 years. Out of 39 total cases, donor’s poor organ condition (n=27) was the most prevalent reason for discontinuation. Conclusions: It is obvious that the shortage of organ donors will continue to get worse. To prevent and reduce unnecessary procurement and discard rate, we should more carefully perform preoperative evaluations and intraoperative inspection. Also, it would be necessary to implement a better control system.
Gun Ick Hwang,Chang Hak Yoo,손병호,Jun Ho Shin,Yong Lai Park,Heung Dai Kim,Yong Shin Kim,Won Kon Han,Won Kil Pae 대한암학회 2004 Cancer Research and Treatment Vol.36 No.3
PURPOSE: Peritoneal metastasis is a crucial factor for the prognosis in gastric cancer, but its diagnosis is difficult before laparotomy. This study analyzed the usefulness of diagnostic imaging and various tumor markers in the detection of peritoneal metastasis in gastric cancer. MATERIALS AND METHODS: The sera from 768 patients with gastric cancer were measured for CEA, CA19-9 and CA125 levels using a commercial immunoradiometric assay. All the patients underwent diagnostic imaging with computed tomography (CT) and ultrasound (US) before laparotomy. RESULTS: Preoperative levels of CEA, CA19-9 and CA125 were above the cut-off levels in 15.4%, 8.7% and 5.7% of all cases, respectively. Eighty-eight patients were diagnosed with peritoneal metastasis by laparotomy. CT and US revealed peritoneal dissemination in 15 of 88 patients (17%). Among the three tumor markers, CA19-9 and CA125 showed similar detection rates of peritoneal metastasis (37.5% and 38.6%, respectively). In particular, the serum CA125 levels showed the best sensitivity (38.6%), specificity (98.4%), and diagnostic accuracy (91.5%), and the highest odd ratio (24.46, 95% CI: 11.17~53.57) for predicting peritoneal metastasis among the markers tested. CEA did not add significant predictive information (p=0.471). CONCLUSION: Preoperative serum CA19-9 and CA125 levels may provide a predictable value in determining peritoneal metastasis in patients with gastric cancer. (Cancer Res Treat. 2004;36:178-181)
Kil Kwang-Soo,Lee Chang-Hyun,Shin Hyun-Ah,Cho Hwang-Yoon,Yoon Ji-Yeon,Lee Gun-Soup,Lee Young-Jae,Kim Eun-Young,Park Se-Pill 한국발생생물학회 2003 한국발생생물학회 학술발표대회 Vol.2003 No.1
Main strategy for a treatment of Parkinson's disease (PD), due to a progressive degeneration of dopaminergic neurons, is a pharmaceutical supplement of dopamine derivatives or ceil replacement therapy. Both of these protocols have pros and cons; former exhibiting a dramatic relief but causing a severe side effects on long-term prescription and latter also having a proven effectiveness but having availability and ethical problems Embryonic stem (ES) cells have several characteristics suitable for this purpose. To investigate a possibility of using ES cells as a carrier of therapeutic gene(s), human ES (hES, MB03) cells were transfected with cDNAs coding for tyrosine hydroxylase (TH) in pcDNA3.1 (+) and the transfectants were selected using neomycin (250 ). Expression of TH being confirmed, two of the positive clone (MBTH2 & 8) were second transfected with GTP cyclohydrolase 1 (GTPCH 1) in pcDNA3.1 (+)-hyg followed by selection with hygromycin-B (150 ) and RT-PCR confirmation. By immune-cytochemistry, these genetically modified but undifferentiated dual drug-resistant cells were found to express few of the neuronal markers, such as NF200, -tubulin, and MAP2 as well as astroglial marker GFAP. This results suggest that over-production of BH4 by ectopically expressed GTPCH I may be involved in the induction of those markers. Transplantation of the cells into striatum of 6-OHDA- denervated PD animal model relieved symptomatic rotational behaviors of the animals. Immunohistochemical analyses showed the presence of human cells within the striatum of the recipients. These results suggest a possibility of using hES cells as a carrier of therapeutic gene(s).
( Gun Wung Na ),( Sang Goon Shim ),( Kil Jong Yu ),( Dae Hyeon Cho ),( Chang Uk Jeong ),( Ji Eun Oh ),( Hyun Chin Cho ),( Kwang Min Kim ),( Hyoun Soo Lee ),( Man Je Park ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: In men, erectile dysfunction (ED), which is defi ned as the inability to achieve or maintain an erection suffi cient for satisfactory sexual performance, is an important issue. There were extensive investigations in clinical and pathophysiological mechanisms with sexual dysfunction during the last decade. However, ED in patients with chronic viral hepatitis has been investigated in few and limited studies, which are often not comparable because they use different survey and patient-sampling methodologies. Moreover, few have evaluated the association of ED and depression in patients with chronic viral hepatitis. Therefore, we assessed the prevalence of ED, and their association with depression in patients with chronic viral hepatitis. Methods: This cross-sectional study was conducted from August 2013 through January 2014. All outpatients with chronic viral hepatitis between the age of 18 and 80 years were considered eligible. The exclusion criteria included well established causes of erectile dysfunction such as liver cirrhosis and alcohol abuse. Erectile dysfunction was assessed with the International Index of Erectile Function-5 (IIEF-5) scale. The Beck Depression Inventory (BDI) scale was used to assess depression of the patient. Results: The prevalence of erectile dysfunction among the patients with chronic viral hepatitis was 40%. Age, employment, peg-interferon, IIEF-5 scores and BDI scores were statistically associated with erectile dysfunction. And also, IIEF-5 scores correlated negatively with age, employment and BDI scores. In a multiple logistic regression analysis, age and depression were independently associated with erectile dysfunction. Conclusions : Patients with chronic viral hepatitis have a high prevalence of erectile dysfunction. Age and depression are independent factors of erectile dysfunction in male patients with chronic viral hepatitis. Evaluation of depression must be included to properly manage erectile dysfunction.