忠州市 地域特性을 反暎한 共同住宅 計劃硏究 : 충주지역 거주자의 APT 선호특성을 중심으로

朴碩鉉,朴義權,柳顯紀,尹勝照,孫泰鎭,金基洙 충주대 2003 産業科學論文集 Vol.11 No.-

The purpose of this research is to analyze the correlation of the characteristics of dwellers and residential preference in apartment housing through the case study of 340 samples in 25 housing estates which were built in Chung-ju city The contents of this research consist of two main parts. The first part is to identify characteristics of dwellers, which might have an influence on residential preference in apartment housing. The second part is to identify the main physical elements of residential preference that can be influenced by the personal characteristics. Thus, this research will contribute to the establishment of the planning methods which increase residential preference in apartment housing, while promoting the quality of residential environment in Chung-ju city.

성인의 만성 기침에 대한 감별진단으로서의 백일해

박완범,박상원,이기덕,이창섭,장희창,김홍빈,김의종,오명돈,최강원 대한감염학회 2004 감염과 화학요법 Vol.36 No.6

목적 : 백일해는 소아기에 발생하는 전염병으로 오랫동안 알려져 왔다. 그러나, 미국과 유럽에서는 1990년대에 들면서 성인에서도 백일해가 유행하며, 만성 기침 환자의 20% 정도가 백일해를 앓는 것으로 보고하고 있다. 저자들은 국내에서 성인 만성기침의 원인으로 백일해의가능성을 확인하고자 하였다. 재료 및 방법 : 2002년 9월부터 2003년 5월까지 서울의 일개 대학보건진료소 또는 일개 시립병원 외래를 방문한 환자 중 기저 폐질환 없이 1주 이상 기침을 하는 성인을 대상으로 Bordetetlla pertussis에 대한 배양검사와 중합효소 연쇄반응검사(PCR)를 시행하였다. 결과 : 1주 이상의 기침을 하는 성인 102명 중 배양검사에서 양성인 환자는 없었으나 3명(2.7%)에서 PCR 양성이었으며 이들 모두 3주 이상 기침이 지속되었고 백일해의 특징적인 증상을 호소하였다. 결론 : 국내에도 성인에서 백일해가 발생하고 있음을 확인하였고 따라서 성인 만성기침의 원인으로 백일해를 감별 진단해야 한다. Background : Pertussis was long considered a childhood illness. However, in the last two decades, it has been reported as a cause of prolonged cough in adolescents and adults in other countries. Infection of Bordetella pertussis was prospectively searched among adults with a persistent cough. Materials and Methods : Adult patients, who visited either the outpatient clinic of a municipal hospital or a university health service center due to cough of more than six days' duration without underlying pulmonary disease, from September 2002 to May 2003, were enrolled. The culture and polymerase chain reaction (PCR) were used for confirming of B. pertussis infection. Results : 102 adult patients with persistent cough were evaluated. 3 (2.9%) patients were PCR positive for B. pertussis. There were no patients with positive culture. All patients with positive PCR had one or more classic symptoms of pertussis and their cough persisted for 3-7 weeks. Conclusion : We confirmed the morbidity of pertussis in Korean adults with persistent cough. Pertussis should be considered as a differential diagnosis of chronic cough in adults.

Y Nd Ba₂Cu₃O 고온 초전도체의 구조와 적외선 투과율에 관한 연구

박기홍,김재욱,김의훈,김채옥 漢陽大學校 基礎科學硏究所 1992 基礎科學論文集 Vol.11 No.-

Y??NdxBa₂Cu₃O?? 고온초전도체의 X-선 회절 분석 과 적외선 투과율 측정은 실온에서 수행되었다. 또한 수송임계 전류밀도는 77K에서 측정되었고, 저항은 80~140K 범위의 온도에서 조사되었으며, 시료들은 고상 반응법에 의해서 제조되었다. 한편 x의 양이 변함에 따라서 전이온도 Tc는 88K 근처의 값을 가지며, 거의 x의 양에 따라 변하지 않았다. 적외선 투과율 측정에서 날카로운 peak들은 472.23~618.87㎝?범위에 있었다. 이것은 특이할 정도로의 low-lying plasmalike edge와 낮은 에너지의 전자적인 여기가 존재함을 나타내는 것이다. 수송임계 전류밀도는 22~92 A/㎠ 범위에 있었다. X-ray pellet diffraction and IR transmittance measurements were been carried out at room temperature. Also the transport critical current density and resistivity of high Tc superconducting Y??NdxBa₂Cu₃O?? system were determined at 77K and in the range of 80~140 K. The sample were prepared by solid state recation. As x varied, the superconducting transition temperature Tc near 88K did not depend on x. In the infrared transmittance measurements, several sharp peaks were observed in the range of 472.33~618.87㎝-1. This indicates that unusual low-lying plasmalike edge and low energy electronic excitation exist. The transport critical current densities determined ranged from 22 to 92A/㎠.

슬관절에 히야루론산 주입후 발생한 활막성 연골종증 : 증례 보고

최의성,김용민,김동수,손현철,박경진,조병기,배승환 충북대학교 의과대학 충북대학교 의학연구소 2009 忠北醫大學術誌 Vol.18 No.2

활막성 연골종증은 비교적 드문 양성 종양으로 관절내 활액막 결체조직의 양성 반응성 이형성에 의해 여러 개의 연골성 결절을 형성하고 이것이 관절내로 유리되어 유리체를 형성하는 질환으로 주로 슬관절에 발생한다. 활막성 연골종증의 정확한 발생 기전은 아직 밝혀지지 않았으나 외상, 감염 등이 원인으로 제시되고 있다. 저자들은 슬관절 내 히야루론산 주입후 발생한 슬관절내 활막성 연골종증을 1 례 경험하였으며, 관절경적 제거술을 통해 만족스런 결과를 얻었다. As a relatively rare benign tumor, synovial chondromatosis forms several cartilaginous nodules by the benign reactive metaplasia of synovial connective tissues within joints, which are loosed into the joints and cause a disease forming loose body mainly in knee joint. Accurate mechanism of synovial chondromatosis has not been clarified yet; however, trauma, infections and others have been suggested as its possible causes. The authors of this study experienced an example of a patient with synovial chondromatosis in knee joint occurred after the injection of hyaluronic acid in the joints and had a satisfactory outcome through the arthroscopic resection.

잡음 섞인 신호의 해석과 잡음제거

조기량,조의주,박영창 여수대학교 1999 論文集 Vol.14 No.2

In this paper. We tried signal analysis and noise cancelling from signal that involved random noise. Also, make a program that can be not only signal analysis for the involved noise signal but also noise cancelling . The result shows a noise cancelling ability of 23.14(dB)(LPF), 23.23(dB)(BPF) from noisy signal. Numerical simulations were carried out by a PC(Pentium-Ⅱ, 400MHz, RAM 32Mbyte) and double precision in numerical calculation.

天安 및 忠淸地域의 産婦人科 應急患者에 관한 臨床的 硏究

李元起,朴忠學,朴鎭完,許義宗,李昌益 단국대학교 1995 論文集 Vol.29 No.-

The objective of this study is to analyze clinical evaluation of 313 patients in Obstetrics and Gynecology who visited Emergency Room in Dankook University Hospital from June, 1994 to December, 1994 for the purpose of successful and perfect emergency care of the patients in Obtetrics and Gynecology in Cheonan-Chungcheong District in the futrure. Today, the goal of modern obstetrics is the well-being of both mother and fetus. And there are many gynecologic diseases which lead the female patient to emergency room with the chief complaint of severe abdominal pain or vaginal bleeding, etc. We have of emergency patients, clinical characteristics of the patients, the time of patient's entrance in emergency room, the monthly distribution of visit, the crowding day of visit, the distribution of the patients according to living area, the admission rate, and the management of the patients, etc. Followings are the results summarized : 1. The mean age was 29.8 years(range form 10 to 85). The mean number of gravidity and parity were 2.0 and 1.1 respectively. The mean number of abortion and living child were 1.0 and 1.0 respectively. 2. The most predominant monthly distribution of visit were August and December. 3. The admission rate was 48.2% and the discharge rate was 49.5%. 4. Distribution of department was Internal Medicine, Pediatrics, Orthopedics, and Obstetrics & Gynecology, in order. 5. The most crowding day of visit was Sunday(22.0%). The peak time of patint's entrance in emergency room was between 20:00 PM and 24:00 PM(24.3%), and the second peak time was between 16:00 PM and 20:00 PM(21.4). 6. Of 313 patients, 53% were known to live in Cheonan city and Cheonan county. 82.7% were known to live in Chungcheong District. 7. In 151 patients who admitted the ward, 53% were obstetric patients and 47% were gynecologic patients. 8. In 80 obstetric patients of admission, the most common chief complaint was labor pain(76.3%). In 71 gynecologic patients of admission, the incidence of disease was abortion(32.3%), ectopic pregnancy(25.4%), and pelvic inflammatory disease(11.3%), in order. 9. Major operations were performed in 40 patients of 151 admitted patients(26.5%). Minor operations including Dilatation and Curettage were performed in 12 patients(7.6%). 10 In 155 patients of discharge, the incidence of disese was abortion(36 patients), pelvic inflammatory disease(20 patients), false labor(15 patients), and uterine bleeding(11 patients), in order.

출혈성 소화성 궤양의 장기 재발률

심기남,정훈용,양석균,홍원선,박의련,박무인,김해련,민영일 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.2

Background/Aims: Bleeding from a peptic ulcer is one of the common and serious complications associated with the rate of reported mortality, which ranges from 5% to 10%. Endoscopic therapy is effective in controlling active bleeding and reducing the emer-gency surgery, the immediate mortality rate and the incidence of early rebleeding. But few recent studies have documented the long-term recurrent bleeding rate after discharge in patients with bleeding peptic ulcers. The aim of this study was to determine the long-term recurrent bleeding rate and factors predisposing to recurrent bleeding. Methods: Eighty-eight patients with bleeding peptic ulcers discharged after medical treatment between Dec. 1990 and Jul. 1992 were included in this study and retrospectively followed up with medical records and telephone interviews. The end point of follow-up was recur-rent hemorrhage, surgery for treatment of ulcer complication, or death. Results: By July 1997, retrospective follow-up was available in 76 patients. Recurrent bleeding occurred in 23 patients (30.3%) with bleeding peptic ulcers and the median follow-up period was 69 months (range, 1 ∼79 months). The estimated cumulative recurrent bleeding rate after 1, 2, 3, 4, 5 and 6 years was 11.8%, 14.5%, 19.9%, 24.2%, 27.2% and 34.2%, respectively. There was no difference between the recurrent bleeding group and the non-recurrent bleed-ing group according to age, sex, prior NSAIDs use, previous history of bleeding or pepticulcer, site of ulcer, stigmata of recent hemorrhage at initial examination, method of treatment and amount of transfusion. Conclusion: Recurrent bleeding occurred in one-third of patients with bleeding peptic ulcers after 6 years of follow-up and one-third of recurrent bleeders rebled within 1 year. The factors predisposing to recurrent bleeding in the long-term follow-up could not be found. Therefore, further studies designed to identify factors predisposing to recurrent bleeding are needed and the evaluation of Helicobacter pylori status in bleeding pepic ulcer is needed because Helicobacter pylori is an important factor of peptic ulcer recurrence.

족부백선의 치료에서 터비나핀과 이트라코나졸의 이중맹검 비교연구

김기홍,최종수,박의수,김상원,김수찬,안성구,서무규,서순봉 대한화학요법학회 1994 대한화학요법학회지 Vol.12 No.2

터비니핀(terbinafine)의 족부백선에 대한 치료효과를 판정하기 위해 6개 병원의 피부과에서 공동연구로 족부백선환자90명에 대하여 치료완료하였으며 2군으로 나누어 터비나핀 1일 250㎎씩 2주간 경구치료와 이트라코나졸 1일 100㎎씩 4주간 치료를 이중맹검으로 실시하여 임상적 및 진균학적인 검사로 치료효과와 약제의 내약성을 평가하였다. 완치율은 터비나핀군은 치료 1주후 6.5%, 2주후 23.9%, 4주후 69.6%, 6주후 89.1%였으며, 이트라코나졸군은 치료 1주후 0%, 2주후 22.7%4주후 59.1%, 6주후 77.3%이었다. 부작용과 내약성은 양군에서 비슷한 성적을 나타내었다. 이상의 결과로 보아 터비나핀 1일 250㎎씩 2주간의 경구투여는 치료율, 안정성 및 부작용에서 이트라코나졸 1일 100㎎씩 4주간 치료효과와 유사하였다. In this randomized double-blind trial on multicenter study, the efficacy of the new antifungal agent, terbinafine was compared with the triazole antifungal agent, itraconazole, in the treatment of patients with various forms of tinea pedis. One hundred and ten patients(55 terbinafine, 55 itraconazole) with tinea pedis were enrolled. Eleven patients were lost to follow-up(5 terbinafine, 8 itraconazole) and 9 reported adverse reaction with premature discontinuation of therapy. And 90 patients were eligible for follow-up until 6 weeks after starting the treatment. Forty six patients received terbinafine 250㎎ daily for two weeks and 44 received intraconazole 100㎎ daily for 4 weeks. They were checked clinical symptoms and mycological improvement with KOH wet mount and culture during the study. Clinical and mycological cure rate of the terbinafine group was 6.5% at 1 week after intialtreatment, 23.9% at 2 weeks, 69.6% at 4 weeks and 89.1% at 6 weeks and that of the itraconazole group was 0% at 1 week after intial treatment, 22.7% at 2 weeks, 59.1% at 4 weeks, and 77.3% at 6 weeks. Adverse reactions and tolerability of both drugs were not different significantly. All these findings suggest that the effects of terbinafine 250㎎ daily for 2 weeks in the treatment of tinea pedeis was similar to that of intraconazole 100㎎ daily for 4 weeks.

여성 긴장성 요실금에서 Stamey술식의 고찰

김민의,박영호,문기혁 순천향의학연구소 1997 Journal of Soonchunhyang Medical Science Vol.3 No.2

The Stamey bladder neck suspension have been performed for female stress incontinence in Soonchunhyang University Hospital from January 1990 to May 1994. This procedure was introduced by Stamey, varying degrees of the success have been reported ranging from 61% to 91% in contemporary series. Someone reported the high recurrence rate with long-term follow-up. Among the 36 patients who received Stamey procedure, 28 patients(78%) receive anterior colporrhaphy for concomitant cystocele simultaneously. The mean follow-up period was 41.4±8.6months, the patient's data were gathered by chart review and the subjective success rate was obtained by questionnaire survey. Urinary retention was the major complication in 8(22.2%),de novo urgency occurred in 4(11%), protracted suprapubic pain occurred in 7(19%), The 20(56%) of the 36 patients were complete dry and 10(28%) were improved. The changes of success rate related to the time of follow-up were; 94.4% immediate after surgery, 88.9% at 6 month, 86.1% at 12 month, 83.3% at 1-5 year. The majority of the failure occurred in the early postoperative period. The 27(90%) of the 30 patients success group received anterior colporrhaphy for concomitant cystocele simultaneously during the Stamey operation. Our success rate was slightly higher than contemporary series, it was suggested that supporting the midurethral segment by anterior colporrhaphy with bladder neck suspension might be the contributing factor for increasing the success rate, but more follow up is warranted.

중합효소연쇄 반응법에 의한 인형거대세포바이러스(human cytomegalovirus)의 신속한 검출

김의종,오명돈,박기호,신형식,이환종,김남중,최강원 대한감염학회 1996 감염 Vol.28 No.4

목 적 : 인형거대세포바이러스(HCMV)는 면역 저하 환자에서 폐렴, 망막염, 간염 등 치명적인 감염증의 원인이다. 전통적인 세포 배양법으로 HCMV를 분리하기까지는 1주에서 4주가 걸리므로 이 바이러스에 의한 질환이 의심되는 경우 신속한 진단법을 이용한 진단이 바람직하다. 저자들은 한국에서 분리되는 야생주 HCMV를 검출하는데 중합효소 연쇄 반응법을 이용할 경우의 진단적 유용성을 알기 위하여, 전통적인 세포배양법으로 HCMV가 분리된 검체를 이용하여 중합효소 연쇄 반응법의 특이도와 민감도를 평가하였다. 방 법 : 국내 야생주 HCMV 15주, 그리고 전통적인 바이러스 배양법으로 HCMV가 분리된 소변 15검체를 대상으로 중합효소 연쇄 반응을 실시하였다. 중합효소 연쇄 반응은 Towne주의 immediate early antigen의 유전자에서 유리된 primer MIE와 AD169주의 immediate early antigen의 유전자에서 유리된 primer IE를 이용하였다. 증폭 산물은 겔 전기영동 후 EtBR으로 염색하여 자외선 하에서 관찰하였다. Primer IE에 의한 증폭산물은 또한, DNA blot hybridization 방법으로 확인하였다. 결 과 : 1) 국내 HCMV 야생주 15주를 대상으로 중합효소 연쇄 반응을 한 결과 primer IE를 이용한 경우에는 100%(15/15)에서 177bp의 증폭 산물이 관찰되었고, 이들 증폭 산물은 모두 probe IE와 보합 결합되었다. primer MIE를 이용한 경우에는 93%(14/15)에서 435bp의 증폭 산물이 관찰되었다. 2) 세포 배양법으로 HCMV가 분리된 소변 15검체를 대상으로 primer IE를 이용하여 중합효소 연쇄 반응을 한 결과 direct gel analysis 법으로는 73%(11/15)에서, 보합 결합법으로는 87%(13/15)에서 관찰되었다. Primer MIE를 이용한 경우에는 direct gel analysis법으로 87%(13/15)에서 435bp의 증폭 산물이 검출되었다. 결 론 : Primer IE와 MIE를 이용한 중합효소 연쇄 반응법은 국내 야생주 HCMV를 신속히 검출하는데 유용한 검사법이다. Background : Human cytomegalovirus(HCMV) can cause pneumonitis, hepatitis, retinitis and other serious diseases in the immunocompromised patients. It takes 1 to 4 weeks to diagnose HCMV infection by conventional virus culture. Therefore, when HCMV diseases are suspected, a rapid diagnostic method such as polymerase chain reaction(PCR), antigen assay or shell vial culture is desirable. We evaluate the sensitivity and specificity of a PCR for the rapid detection of HCMV wild strains in Korea. Methods : We used 2 sets of primers ; primer IE and primer MIE derived from the sequence for immediate early gene of AD169 strain and Towne strain, respectively. Fifteen clinical isolates of HCMV, suspended in MRC-5 cells, were amplified by PCR. Fifteen urine specimens which were positive for HCMV by conventional virus culture were also amplified. Amplification products were analyzed by polyacrylamide gel electrophoresis. The products from PCR with primer IE were also identified by DNA blot hybridization. Results : PCR using primer IE gave the PCR products in all of the 15 HCMV wild strains. All of these were hybridized with probe IE. When primer MIE were used, 93%(14/15) of the wild strains showed amplified bands by direct gel analysis. When the urine specimens were amplified by PCR with primer IE, amplified bands were seen in 73%(11/15) by direct gel analysis ; 87%(13/15) by hybridization method. When primer MIE were used, 87%(13/15) of the urine specimens showed the PCR products by direct gel analysis. Conclusion : Polymerase chain reaction with primer IE and MIE may be a specific and sensitive diagnostic method for rapid detection of HCMV wild strains in Korea.