Hepatic Cirrhosis Occurring in a Young Woodchuck(Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus(WHV)

Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea

Elderly kidney transplant recipients have favorable outcomes but increased infection-related mortality

임정훈,Lee Ga Young,Jeon Yena,Jung Hee-Yeon,Choi Ji Young,CHO, JANG-HEE,Park Sun Hee,김용림,Kim Hyung-Kee,Huh Seung,유은상,Won Dong Il,Kim Chan-Duck 대한신장학회 2022 Kidney Research and Clinical Practice Vol.41 No.3

Background: The number of elderly patients with end-stage kidney disease has been increasing, but the outcomes of kidney transplants (KT) remain poorly understood in elderly patients. Therefore, we evaluated the clinical outcomes of elderly KT recipients and analyzed the impact of elderly donors. Methods: This retrospective cohort study included patients who underwent KT between 2000 and 2019. KT recipients were divided into four groups according to a combination of recipient and donor age (≥60 or <60 years); elderly recipients: old-to-old (n = 46) and young-to-old (n = 83); young recipients: old-to-young (n = 98) and young-to-young (n = 796). We compared the risks of mortality, graft failure, and acute rejection between groups using Cox regression analysis. Results: The incidence of delayed graft function, graft failure, and acute rejection was not different among groups. Annual mean tacrolimus trough level was not lower in elderly recipients than young recipients during 10-year follow-up. Mortality was significantly higher in elderly recipients (p = 0.001), particularly infection-related mortality (p < 0.001). In multivariable Cox regression analysis, old-toold and young-to-old groups had increased risk of mortality (adjusted hazard ratio [aHR], 2.89; 95% confidence interval [CI], 1.14– 7.32; p = 0.03; aHR, 3.06; 95% CI, 1.51–6.20; p = 0.002). However, graft failure and acute rejection risks were not increased in elderly recipients. Conclusion: In elderly recipients, graft survival and acute rejection-free survival were not inferior to those of young recipients. However, mortality, especially risk of infection-related death, was increased in elderly recipients. Thus, low immunosuppression intensity might help decrease mortality in elderly recipients.

코스튬플레이어들의 라이프스타일과 행동특성에 관한 연구

정혜영,정희경,서용한,오희선,이명희 한국의류산업학회 2004 한국의류산업학회지 Vol.6 No.1

Costume plays have been of interest to young people in the recent years. The much increased interest in costume plays has prompted many researchers to verify the behavior characteristics of costume players Despite the importance of the costume play, there has been no systematic study of it. The purpose of this study is to demonstrate the influence of life style on behavior characteristics of the costume player. The subjects of this study were members of the web sits(wwwcosmakercom). A total of 155 subjects responded to the questionnaires and the 143 responses were used for further data analysis. The data was analyzed by factor analysis, cluster analysis, and one-way ANOVA. These were the results of the stud: First, costume player groups are classified into three sub-dimensions: other people-oriented, show-off oriented, and exclusive ego oriented. Second, the behavior characteristics of costume player are significantly shown among those groups.

Pseudomonas putida SM25에서의 catBC 유전자의 발현과 catBCA Operon의 Promoter 부위 분석

정영희,민경희,김지영,최순영 숙명여자대학교 자연과학연구소 1997 자연과학논문집 Vol.- No.8

catBCA operon은 catechol로 부터 β-ketoadipate enol-lactone까지 ortho-경로로 분해되는 효소들을 암호하고 있으며, 이들 유전자들은 서로 연관된 전사 조절을 받고 있다. Pseudomonas putida SM25의 염색체로 DHA로 부터 catBCA promoter부위를 pRS415a에 클로닝하여 재조합 plasmid인 pRSB1을 제조하였다. 이 promoter의 작동을 lacZ의 reporter gene인 β-galactosidase의 활성으로 그 발현을 측정하였으며, 그 결과 Escherichia coli내에서의 promoter의 작동은 promoter가 없는 경우의 세표에서 보다 그 활성이 약 10배 높게 나타났다. S1 mapping으로 조사한 결과 catBCA promoter부위는 catB의 번역 개시코돈으로부터 약 45bp upstream부위에 전사개시 부위가 있는 것으로 추정된다. catBC promoter의 작동에 의한 mRNA의 발현은 RT-PCR을 이용하여 간접적으로 조사한 결과, cis, cis-muconate로 유도한 경우 mRNA발현은 현저하게 높게 나타내었으며, P. putida cell에서의 발현이 E. coli cell내에서 보다 높게 나타났다. catBCA genes are encoded for the dissimilation of catechol to β-ketoadipate enol-lactone by ortho-pathway and are regulated under corrdinate transcription regulation. Promoter region of catBCA operon was inserted into a promoter probe vector, pRS415a with lacZ gene, constructing recombinant plasmid pRSB1 carrying pRS415a-catBCA promoter in order to analyze expression from the catBC promoter. The transcription level of pRSB1 was increased 10 fold higher than that of pRS415a. The in vivo transcription initiation site of the catBCA operon was determined by S1 nuclease protection analysis, indicating that it was located on about 45bp upstream from the initiation codon of the translation. Transcription level of the catBCA operon in Pseudomonas putida SM25 was analyzed by RT-PCR indirectly. mRNA of catBC genes was synthesized in both the cells of P.putida PPO200-2 and Escherichia coli NovaBlue under the control of the promoter with induction of cis, cis-muconate.

미치광이풀 모상근 배양에서 Tropane Alkaloid 생산성 증진을 위한 최적 생물학적 엘리시터 선발

정희영,강승미,강영민,김용덕,양재경,정영관,최명석 Plant molecular biology and biotechnology research 2003 Plant molecular biology and biotechnology research Vol.2003 No.-

Scopolamine and hyoscyamine which belong to tropane alkaloids are the pharmaceutically valuable anticholinergic drugs. In order to increase the productivities, the effects of elicitation were investigated during hairy root cultures of Scopolia parviflora. Biotic elicitors originated from 3 fungi and 1 yeast were prepared as homogenate and supernatant and added to 3-week-old cultures. Both of homogenate and supernatant of Candida albicans elicitors increased the scopolamine production. The production of hyoscyamine was enhanced by homogenate of Fusarium solani and supematant of C. albicans. Most of the other fungal elicitors were also improved on the tropane alkaloid production compared to non-treatment. Among the elicitors tested, C. albicans was proved the optimal biotic elicitor on tropane alkaloids production. These results will be served mass production of tropane alkaloids by large-scale production.

성인의 급성 설사에 대한 로페라미드 옥사이드의 효과: 위약과의 무작위 이중 맹검 비교 다시설 시험

박영태,정희진,박중원,이계희,김나영,임선희,윤병철,한동수,이오영 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.31 No.5

한국 기혼여성의 일상적 삶의 질 향상에 관한 연구 (3) : 한국 기혼여성의 삶의 질 향상을 위한 프로그램 개발 연구 Development of A Program for the Enhancement of Korean Married Women's Quality of Life

김정자,최순,김선희,정영숙,김경연,심혜숙,문소정 부산대학교 여성연구소 1999 여성학연구 Vol.9 No.1

The purpose of this study was to develop a program for the enhancement of Korean married women's quality of life(LQ) based on the results of the first year study(1996) and the second year research(1998). In order to construct a program, a psycological type test was conducted to 505 women and four preliminary programs were carried out focusing on self-esteem, understanding of one's own personality dynamics, efficient communication, positive emotion, social belongingness and expressions of feelings of unfinished business. For the final program, Jung's theory of psychological type(MBTI), Satir's family therapy approach and psychodrama were applied. An experimental and a control group were designed consisting 16 women for each group. The program was carried out for 6 weeks for the experimental group. The result of treatment were as follows: l)There was a difference statistically in LQ related to family harmony, self-achievement and improvement of relationship with in-laws. 2)There was a statistical change in psychological factors of expression of feelings, self-esttem, communication, and positive emotions. 3) The program participants self reports indicate that the program was effective for the reconstruction of family relationship, self-understanding, group coherence, and instillation of hope. The reports also shows that the program was effective for the perceptual changes in parent-child, wife-husband and siblings' relationships. In conclusion, the program developed for the enhancement of Korean married women's life quality(LQ) based on the Jung's psychological type theory, Satir's family therapy approach and psychodrama was effective for the improvement of LQ.

연조직 측모에 관한 분석

장영일,최희영,신수정 대한치과교정학회 1995 대한치과교정학회지 Vol.25 No.5

본 연구에서는 단정한 측모를 지니고 교합이 양호한 성인을 대상으로 몇 가지 연조직 분석을 시행하고, 이를 여러 다른 연구에서의 기준치와 비교하여, 향후 교정치료 계획시에 도움이 되고자 하여 시행하였다. 측모가 단정하고 교합이 양호한 성인 남, 녀 각 25명(총50명)을 대상으로 촬영한 측모 두부X선계측사진에서 연조직 측모의 각도, 거리 계측을 시행하여 facial convexity angle, nasolabial angle, H-angle, Z-angle, E-line to upper lip, lower lip과 Sn-Pog´to upper lip, lower lip에 대한 남녀의 평균과 표준편차를 구하였고, 국내의 다른 연구와 비교하여 다음과 같은 결과를 얻었다. 모든 항목에 대해 백인에 비해 전방 돌출된 안모의 특징을 보였으며, 국내의 다른 연구의 수치에 비해서도 본 연구의 표본의 안모는 전방 돌출되어 있었다. The purpose of this study to analyze characteristics of soft tissue profile in Korean young adults. The sample consisted of 50 young adults (25 males and 25 females) who had pleasing and normal occlusion. Soft tissue analysis (facial convexity angle, nasolabial angle, H-angle, Z-angle, E-line to upper lip, lower lip, Sn-pog´to upper lip, lower lip) was performed on lateral cephlograms. Mean and standard deviation was obtained. When compared by other studies, mean profile of this sample was relatively straighter and both the upper and lower lips was more protrusive.

식물생장조절제 Seaweed extracts(GA14)의 수도 품종간 생육 및 수량에 미치는 효과

송재영,김용일,박보영,정재영,최현구,정종태,이희봉 충남대학교 농업과학연구소 2004 농업과학연구 Vol.31 No.1

This study was carried out to identify the effects of seaweed extracts(GA14) on growth of two rice cultivars, Junambyo and Donganbyo. Seedling qualities of two cultivars were better in all items including heading dates at early stage treated at seedling plus 2-3 leaf stages than at single treatment of seedling. Ripening ratio of Junambyo in paddy field was increased 0.3% by seaweed extracts(GA14) treatment, but that of Donganbyo decreased 0.5%. 1,000 grain weight of Junambyo and Donanbyo by seaweed extracts(GA14) treatment was two to four grams higher and the yield of two cultivars was also higher by three to four percent. Appearance characters of two rice cultivars was high in head, while damaged, chalky and crack rate were low at seaweed extracts(GA14) treatment. Protein, moisture and amylose characteristics related to table quality of Junambyo were not different by seaweed extracts treatment, but table values was high in only treatment. Donganbyo was also similar to Junambyo, but table quality was slightly high at non-treatment.

분말혼화제를 사용한 콘크리트 포장(包裝)화에 관한 기초적 연구

한다희,김영주,박무영,박희곤,이영도,정상진 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

Most concrete is recently made of an aggregate which is properly absorbed, and carried in it according to its capability at every fields. We have been close to demand new capability of high flowing and enduring for specific concretes. That is difficult to cope with claiming the efficiency on deterioration from lack of a high quality aggregate. Therefore, For solving the problems we apply to method of packaged dry combined materials for concrete using dried materials. That is to say that it is a kind of making into an instant. In this study, There is a purpose to present fundamental data, comparing and analyzing a phenomenon of aggregate's absorption following the rate of adding water, for using existing materials.