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      • KCI등재

        전환장애와 감별해야할 Meige 증후군 1예

        임세원,김진세,정인과,박민규,이대희 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.3

        Meige 증후군은 안검경련과 구-하악부의 근긴장이상을 특징적으로 보이는 신경학적 임상증후군이다. 발병원인은 아직 불분명하나 아세틸콜린과 도파민의 신경활성과다(excess neuronal activity)가 원인으로 여겨지고 있으며, 치료로는 향도파민성약물과 항콜린성약물, 그리고 보튤리듐독소 주사가 이용되고 있다. 그러나 증상양상이 다양하며 심리적 영향을 받으므로 전환장애 혹은 불안장애 등의 정신과적 문제로 오진되는 경우가 있다. 저자들은 49세 여자로 초기에 전환장애로 진단되었으나 Meige 증후군임이 밝혀져 성공적으로 치료되었던 환자 1례를 경험하여 문헌고찰과 함께 보고한다. A Meige's syndrome is a rare neurological syndrome characterized by blepharospam and oro-mandibular dystonia. Its pathophysiology is not clearly determined yet, but the hypothesis of dopaminergic and cholinergic hyperactivity is most widely accepted. Anticholinergic drugs, antidopaminergic drugs and botulism toxin injection are currently used for the treatment of Meige's syndrome. The Meige's syndrome could be misdiagnosed as a psychiatric disorder such as conversion disorder or anxiety disorder, because clinical features of the Meige's syndrome are very variable and affected by psychological factors. The authors experienced one case of a 49-year-old female patient who was initially misdiagnosed as conversion disorder but confirmed later as Meige's syndrome, and then successfully treated.

      • 일부 종합검진 수검자에 비만도 및 혈중 지질이 혈압에 미치는 영향

        임대식,함정오'김화성'이성수 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

        This study was conducted to evaluate blood pressure associated with body mass index and blood lipids. Study subjects were 3,076 persons (1,623 males and 1,453 females) who visited to General Health Screening Center located in Chonan. Data were collected from 2001 to 2003. Height, weight and blood pressure were measured by a trained nurse. The level of total cholesterol, HDL cholesterol, triglyceride, and fasting blood sugar were selected as biometric test variables. Statistical analysis, such as t-test, simple correlation, and stepwise multiple regression were performed using SAS package program. The mean (standar deviation) of age, BMI, systolic blood pressure, diastolic blood pressure, fasting blood sugar, triglyceride, total cholesterol, HDL cholesterol, and LDL cholesterol in study subjects were 48.4 ±11.8 years, 23,7 ± 3.2 kg/m^(2), 124.6 ± 16.3 mmHg, 80.9 ± 10.7 mmHg, 97.6 ± 24.9 mg/㎗, 154.4 ± 105.6 mg/㎗, 203.2 ± 39.2 mg/㎗, 51.0 ± 12.8 mg/㎗, and 121.8 ± 35.6 mg/㎗, respectively. In multiple regression analysis of BMI and blood lipids on systolic blood pressure after controlling for confounders (age, sex, and fasting blood sugar), BMI, HDL cholesterol, and triglyceride were found to be significant positive independent predictors of systolic blood pressure. In multiple regression analysis of BMI and blood lipids on systolic blood pressure after controlling for confounders (age, sex, and fasting blood sugar), BMI, triglyceride, HDL cholesterol, and LDL cholesterol were found to be significant positive independent predictors fo systolic blood pressure. With above results, it was found that BMI and blood lipids were significantly associated with blood pressure.

      • KCI등재

        Identification of Novel Endo-β-1,4-glucanase Isoforms fromBursaphelenchus Species (Nemtoda: Aphelenchoididae)

        Dae-Weon Lee,Il Sung Moon,강재순,Hyun Jung Choe,최재영,제연호,이시혁,Hye Rim Han,Kook-Jin Lim6,Young Ho Koh 한국응용곤충학회 2007 Journal of Asia-Pacific Entomology Vol.10 No.2

        Bursaphelenchus xylophilus has been recognized as a causal pathogen of pine wilt disease (PWD). In order to identify relevant molecular biomarkers, we selected a variable region of endo-β-1,4-glucanase (β14-gcn) which was cloned from the cDNA of B. xylophilus and B. mucronatus. We then identified three novel β14-gcn isoforms: Bm-β14-gcn and Bm-β14-gcni from B. mucronatus, and Bx-β14-gcn from B. xylophilus. Bm-β14-gcn and Bx-β14-gcn were found to be identical, whereas Bm-β14-gcni was unique to B. mucronatus. These isoforms are Bursaphelenchus-specific and may be employed as molecular markers for the diagnosis of PWD. Our phylogenetic analysis showed that these β14-gcns from Bursaphelenchus species were associated most closely with fungal β14-gcns.

      • Improved Micropropagation of Root Chicory, Cichorium intybus L. var. sativus.

        Lim,Jung-Dae,Yang,Deok-Chun,Lee,Hyeon-Yong,Kim,Jong-Dai,Lee,Jin-Ha,Sung,Eun-Soo,Yu Chang-Yeon 한국자원식물학회 2004 Plant Resources Vol.7 No.1

        The establishment of an efficient protocol for plant regeneration and micropropagation from leaf explant cultures of Chicory, Cichorium intybus L. var. sativus. is reported. Callus formation rate appeared 100% from explant in all growth regulators, but calli formed in the prensence of naphthaleneacetic acid (NAA) were appeared very compact and non-embryogenic state. The regenerated shoots were obtained from leaf explant cultures on solid MS medium containing different concentrations of cytokinins and auxin. The highest number of shoots (5.7) per explant and shoot growth (2.8cm) was obtained on MS medium containing 0.1 mg BAP L^-1 and 0.1 mg NAA L^-1. Indole acetic acid was the most suitable auxin for root formation among three auxins tested. 2,4-D had no effect on shoot and root formation.

      • Effect of Photoperiod, Temperature and True-leaf Stage in Bolting Rate of Chicory (Cichorium intybus L. var. sativus)

        Lim,Jung-Dae,Seo,Jeong-Sik,Lee,Hyeon-Yong,Kim,Jong-Dai,Lee,Jin-Ha,Yu,Chang-Yeon 한국자원식물학회 2004 Plant Resources Vol.7 No.1

        Root chicory (Cichorium intybus L. var. sativus) is potential alternative medicinal and sugar crop which accumulates a high amount of linear polyfructan, inulin in its roots. A problem in root production is that over-wintered stock plants often flower. Once the plant becomes reproductive, stem elongation and root growth slows and floral buds arise from every node, rendering the plants useless for propagation. The objectives of this research was to examine the effectiveness of manipulating environmental factors containing photoperiod, temperature and number of leaf states. The experiment was performed in growth chamber to create two photoperiods (8 h, and 16 h) with three temperature regimes (5℃/3℃, 10℃/8℃, and 15℃/13℃ day/night temperature) for a total of six treatments on three type of true-leaf stage of plant. Data of bolting rate, shoot and root length, shoot and fresh weight was invetigated in each treatments. This is the first report on changes in bolting rate and shoots and roots production during a whole growing season and differences in the effect of cold and photoperiod treatment depending on the true-leaf stage of plant.

      • Au를 공침한 SnO₂후막센서의 가스 감응 특성

        성정훈,강대원,이윤수,임준우,홍영호,이덕동 경북대학교 센서기술연구소 1998 센서技術學術大會論文集 Vol.9 No.1

        High selective and sensitive thick film type methane gas sensors were fabricated and their sensing characteristics for various hydrocarbon gases were investigated. Raw material, SnO_(2)/Au, prepared by coprecipitation was even grain size. SEM, TEM, BET and XRD analyses were carried out for investigation of surface morphology and crystalline structure. The thick film devices using the above materials exhibited high sensitivity to methane gas at the operating temperature of 400°C. The sensitivity of SnO_(2)/Au+Pd thick film devices to methane gas was higher than that to the other hydrocarbon gases such as iso-butane and propane. The optimal adding amounts of Au and Pd were 1wt.% and 3wt.%, respectively. The sensitivity, S, is defined as {(R_(A)-R_(G))/R_(A)}><100, which R_(A) and R_(G) are resistance in air and that in the gas ambient, respectively.

      • 임신중 산전 초음파로 진단된 자궁근종의 임상적 고찰

        서정호,김윤숙,김대원,이동운,최규연,이정재,이임순 순천향의학연구소 2003 Journal of Soonchunhyang Medical Science Vol.9 No.1

        Objectives: To study the clinical manifestations; time, mode of delivery, size of myomas and outcome of pregnancy in cases of myomas that were detected prior to pregnancy or during the antenatal care and after delivery. Methods: We statistically analyzed 76 patients with uterine myomas in pregnancy admitted to Soonchunhyang Seoul Hospital during the period of Jan. 1999 and Dec. 2001. Results: The results are as follows. 1. The mean age of patients in the detected group and undetected group were 32.9 years and 32.3 years, respectively. There was no difference in the proportion of primarity between the detected group(98.2%) and the undetected group(79.6%) 2. The most common type of uterine myoma in both groups was intramural myoma (detected group 94.1% vs undetected group 81.3%). The uterine myomas were most commonly located in the anterior portion and fundus(detected group 52.9% and 23.5% respectively vs undetected group 47.4% and 23.7% respectively) and the proportion was not significantly different between the two groups. Uterine myomas with a diameter of 3cm or more in the detected group were detected by clinical examination and ultrasonogram. Rate of uterine myomas with a diameter of 3cm or more in the detected group is 76.5% and less than 3cm is 54.2% which detected incidentally at delivery. 3. The proportion of term infants were detected group 88.2% vs undetected group 91.5%. 4. The most common indications for cesarean section in both groups were cephalopelvic disproportion and repeated cesarean section (detected group 41.2% and 45.8% respectively vs undetected group 11.8% and 18.6% respectively) and there was no significant difference between the two groups. 5. Secondary pathologic changes in the all myomectomy specimens were degeneration in both groups but there was no necrosis or sarcomatous change. 6. Antenatal complications were preterm labor, premature repture of membranes, spontaneous abortion, malpresentation, and placenta previa. Intrauterine growth retardation and placental abruption were not seen in both groups. Conclusion: Myoma detected by ultrasonogram before or during pregnancy is not a significant implication of pregnancy outcome.

      • 정보화시대의 공동체 : 정보화의 진전과 기업·소비자 관계 변화를 중심으로

        이대식,김성국,김영삼,신종국,임정덕,조영복,조정문 釜山大學校 商科大學 2000 釜山商大論集 Vol.71 No.-

        In this study, we questioned about the possibility of the formation of the new community like relationship at the market on the contrary to the traditional market relationship. We conjectured that kind of new community like relationship may possibly arise because of wide spread of new information technology at market behavior of both consumer and producer side. Traditional buyer-seller relationship was characterized as an anonymous one-shot relationship, however, recent changes were mainly emphasized the rich mutual interactions from both sides. Producers needs more consumer side informations as well as consumers begin to participate on production side at more organized level. Some theoretical studies predict that more rich social relationship will appear at the market since the adoption and wide spread of new information technology. We assume that main functions and ingredients of the community are first, the coordination mechanism which reduces conflicts among community members and second, functional efficiency which meets the common needs of community and third, communicational rationality which enhances the integrity of community members. We surveyed about 100 small and medium sized firms located at Pusan and Kyung-Nam area in order to find out whether firms have community like relationship with their consumers. We fine that most of firms realize the impotance of consumer networks, however most of firms consider this kind of network as a marketing strategy and a source of product design instead of more community oriented characteristics like mutual trust building and social interactions.

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