폐경 후 여성의 심혈관질환 예방을 위한 식사중재에 대한 준수도(adherence) 평가

정경아,김상연,우정익,장유경 漢陽大學校 韓國生活科學硏究所 2001 韓國 生活 科學 硏究 Vol.- No.19

The purpose of this study is to assess the adherence to dietary intervention for prevention of coronary heart disease (CHD) in postmenopausal women by observing changes of antioxidant vitamins and fatty acid composition in dietary intake and seam level. The subjects with hypercholesterolemia (TC≥240mg/dl) were treated with one of hormone replacement therapy (HRT group), dietary intervention (DIET group) or combination of hormone replacement therapy and dietary intervention (HRT+DIET group) for 12 weeks. The results were as followed. Mean daily nutrient intakes were not significantly changed in the HRT group, but were significantly changed in the DIET group and the HRT+DIET group. Especially, dietary vitamin A and E intakes were increased from less than 75% to more than 90% of RDA for Korean in the two groups. With changes of dietary intakes, serum vitamin A and E levels were also significantly increased in the DIET group and tended to increase in the HRT+DIET group. Dietary fatty acid composition was also not significantly changed in the HRT group, but was significantly chanced in the DIET group and the HRT+DIET group. With changes of dietary fatty acid composition, serum phospholipid fatty acid composition was significantly changed in the DIET group and the HRT+DIET group although there was tendency of returning to initial value after 12 weeks. Judging from changes in serum phospholipid fatty acid composition, subjects' adherence to dietary intervention tended to decrease after 12 weeks. However, the changes of antioxidant vitamins and fatty acid composition in dietary intake were compatible with the changes of those in serum level, and we can conclude that dietary intervention was adhered quite well by subjects.

SNS의 뉴스 콘텐츠 이용동기가 뉴스 콘텐츠 유형별 이용량에 미치는 영향 : 참여행위의 매개효과 검증을 통하여

장지연(Ji Yeon Chang),전가영(Ka Young Jeon),유세경(Sae Kyung Yu) 한국언론정보학회 2020 한국언론정보학보 Vol.104 No.-

본 연구는 변화하는 미디어 환경에서 사람들이 어떠한 목적을 가지고 소셜미디어에서 뉴스를 이용하는지 이용 동기를 알아보고, 대표적 콘텐츠 유형별 이용량에 영향을 미치는 이용자 참여행위의 매개효과 검증을 실시했다. 연구 결과, 유튜브 뉴스 콘텐츠를 이용하는 사람들은 다양성을 충족 받고자 하고, 자신과 유사한 견해를 가진 뉴스를 추구한다는 동기가 강했고, ‘좋아요’표시나 댓글 쓰기, 공유 행위 등 참여행위의 매개 효과를 검증한 결과, 유튜브 뉴스 콘텐츠 이용량에 유사견해의 추구 동기는 매개효과가 없는 직접효과만이 유의하고, 다양성 추구의 동기는 참여행위가 매개되지 않으면 이용량을 예측할 수 없는 완전매개효과가 있는 것으로 나타났다. 카드뉴스 콘텐츠에서는 편리성 및 맞춤제공의 동기와 습관적 소비 동기가 요인으로 추출되었지만 이용자 참여행위는 이용량에 대해 유의한 효과 없이 이용 동기가 이용량에 모두 직접적 영향을 미쳤다. 소셜미디어에 원문 그대로 재매개되는 언론사 뉴스 콘텐츠의 경우 다른 유형과는 차별적으로 시의성 충족의 동기가 가장 중요했다. 최근에 일어난 이슈를 실시간으로 소비하고자 하는 욕구와 더불어 의견 교환 및 견해의 비교 동기 역시 유의하게 나타나 기성 매체의 콘텐츠가 소셜미디어 플랫폼에서 새로운 의미로 재가공된다는 점을 확인했다. 재매개된 언론사 뉴스 이용량에 시의성 충족의 동기는 매개효과가 없는 직접효과만 유의했고, 의견교환 및 견해의 비교 동기는 이용자 참여행위의 완전매개효과를 확인했다. 이 연구는 소셜미디어를 활용한 뉴스 콘텐츠 생산과 유통, 소비과정에서 이용자들의 이용 동기와 참여행위를 고려한 전략을 모색할 수 있도록 돕고, 소셜미디어 뉴스의 균형과 조화를 위한 자료를 제공했다는 점에서 의의가 있다. This study identified the motivations for using 3 different news content types on social media platforms and verified mediating effects of user participatory behaviors that affect the usage of each news content type. Studies have shown that those who use YouTube news content have strong motivation to ‘seek for diversity’ and to ‘pursue news with similar views’. In addition, participatory actions: such as ‘like’, ‘writing comments‘ and ‘sharing‘ mediated ‘seeking for diversity’ motivation and the usage of YouTube news. However motivation for ‘pursuing news with similar views’ had no mediating effect. Card news usage showed that the motivation for ‘convenience and curation’ and ‘habitual consumption’ found to have strong positive relation, but the user participatory behavior had no significant mediating effect on the amount of use. Unlike other news contents, original news that are re-mediated via social media showed to have a positive relationship with the motivation for ‘timeliness’ and ‘exchanging opinions and comparing views’. This result confirmed that as original news content transported into social media, even if the content do not change the meaning for the usage change. The motivation for meeting ‘timeliness’ was only noted to have direct effects towards the usage without any mediated effects, but the motivation for ‘exchanging opinions and comparing views’ confirmed the complete mediating effect of user participation. The research is meaningful in that it helped to explore strategies that took into account users’ motives and participation in the process of producing, distributing and consuming news content using social media.

외상성 고막 천공에 관한 임상적 고찰

유연창,정관기,양미경,장철호 최신의학사 1990 最新醫學 Vol.33 No.10

재발성 가와사끼병의 임상양상과 검사소견

유승택,최은정,이창우,오연균,박승택,윤향석 圓光大學校 醫科學硏究所 2003 圓光醫科學 Vol.18 No.2

노년기 여성의 식이 섭취 조사를 위한 반정량 식품섭취빈도조사지 개발에 관한 연구

김상연,정경아,장유경 漢陽大學校 韓國生活科學硏究所 2000 韓國 生活 科學 硏究 Vol.- No.18

A data based semiquantitative flood frequency questionnaire, which can be used in studies investigating relationship between diet and cardiovascular diseases in Korean elderly women, was developed. The questionnaire is a 30-minute, face-to-face administered instrument designed especially for assessing food and mixed dishes. Food items were selected from 3-day flood records. 140 food items were finally selected based on the frequency of consumption and the contribution of specific foods to the total population intake of the following 11 nutrients: energy, carbohydrate, protein, fat, cholesterol, SFA, MUFA, PUFA, β -carotene, vitamin C, and vitamin E. The percentage of total nutrient intake which each food provides is presented for the top 50 contributiors of each of the nutrients listed above, as well as the proportion of the population consuming them. Foods sometimes overlooked as important sources are found in some instances to be quantitatively important to population intake, such as carrot as an independent sources of carotenoids. Portion size of each food item was determined considering the mean and median values of the amounts consumed by subjects in the preliminary survey. Frequency of consumption was asked in nine categories ranging from more than 'three times a day' to 'almost never'. A nutrient database was compiled from many sources, but mostly from Korean nutrition society. This flood frequency questionnaire should be useful to epidemiologists with a substantive interest in dietary etiologies and it can reasonably estimate the usual dietary intakes among postmenopausal women for cardiovascular disease study, but shorter form of questionnaire and validation would be needed.

Guar gum의 섭취 수준과 기간이 흰쥐의 영양소 흡수율에 미치는 영향

김상연,선영실,장유경 漢陽大學校 韓國生活科學硏究所 1993 韓國 生活 科學 硏究 Vol.- No.11

This study was performed to investigate apparent absorption of nutrients according to level and duration of guar gum intake. Eighteen male rats of Sparague-Dawley strain weighing 50g were blocked into three groups : FF, 5G, 10G(Fiber Free, 5% Guar gam, 10% Guar gum). Balance studies were conducted at 2nd week, 4th week and 8th week. Feed in-take body weight gains, apparent absorption of protein, fat, Ca and P were measured. The results obtained in this study were summarized as follows : (1) Feed intake was not significantly different among the groups during each balance studies. Weiht gain was decreased according to level of guar gum intake during each balance studies. (2) Protein apparent absorption of 5G were not significantly different with that of 10G at 2nd week and 4th week but at 8th week protein apparent absorption of 10G was singificantly lower than that of 5G According to duration of guar gum intake, protein apparent absorption of FF and 5G were not significantly different. Wherease protein apparent absorption of 10G was significantly decreased at 8th week. (3) Fat and Ca apparent absorption were not significantly different among groups at 2nd week. Fat apparent absorption of 10G was not significantly lower than that of 5G at 4th week and 8th week. According to duration of guar gum intake, fat and Ca apparent absorption of FF and 5G were not significant different. But fat and Ca apparent absorption of 10G was significantly decreased according to duration of fur gum intake. (4) Phosphorus apparent absorption were not significantly different among groups at 2, 4th week. But phosphorus apparent absorption of 10G were significantly higher than that of 5G at 8th week. According to duration of guar gum intake, phosphorus apparent absorption of FF and 10G were not influenced. But Phosphorus apparent absorption of 5G was significantly decreased according to duration of guar gum intake. From the results of this study, we could recommend 5% guar gum in diet of obese man and di abetics.

환자중심적 측면에서 본 여성전문병원 병동부의 실내환경 분석연구

황연숙;장윤정;김유연 한양대학교 2007 韓國 生活 科學 硏究 Vol.27 No.1

The purpose of this study is to analyze the wards of women's hospitals in the perspective of patientfocused design. An evaluation checklist of the patient wards was applied to seven women's hospitals that have constructed or remodeled since 2000. The findings indicate that patients' room was generally patient-focused in terms of social interaction and privacy. However, the lacks of kitchenette, balconies, and dimmers were evaluated negatively. Among the patients' room, corridor, and patients' lounge, the lounge was the most negative in terms of patient-focused design. Privacy and home-likeness were insufficient in patients' lounge while control of ventilation and sunlight was well considered. The future study needs to develop advanced survey and interview methodologies in order to support the relevant results.

정신분열병과 Neuregulin 1 유전자의 연합연구

박동연,이유상,조은영,조승희,장용이,전현옥,장수연,윤세창,김종원,홍경수 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.3

Objectives : The authors recently found a suggestive evidence of linkage of chromosome 8p21-12 to schizophrenia in Korean multiplex families. Neuregutin 1 (NRGI) was identified in this locus as a positional and functional candidate gene for Schizo-phrenia, through several independent studies with European and Chinese populations. The purpose of this study is to determine whether NRGl is associated with schizophrenia in Korean population. Methods : Three SNPs (SNP8NRG221533, SNP8NRG241930, SNP8NRG243177) and two microsatellites markers (478B14-848,420M9-1395) located at the 5' end of NRGI were genotyped for 242 unrelated schizophrenia patients and the same num-ber of normal controls. Genetic association was tested by χ²-test (df=1). Not only for the whole patients group but also for asubgroup of patients with auditory hallucination. This subtype showed stronger linkage with chromosome 8p12 in the prior study of the authors with multiplex families. Results : G allele of SNP8NRG241930 was significantly in excess in the subgroup of patients with auditory hallucination compared to the control group (p=0.03, 0R=1.76). We also found that 3 SNPs haplotype TTC (p=0.04, 0R=0.58) and five markers haplotype TTC53 (p=0.01,0R=0.49) were associated with schziophrenia with a protective effect. Three SNPs haplotype CGT which is a part of the at-risk haplotype of the Icelandic schizophrenia families was found in excess in the patients group but no significant association was observed. Conclusion : NRGI might either play a mle in the predisposition to schizophrenia or be in linkage disequilibrium with a causal locus of this illness.

고콜레스테롤혈증을 지닌 폐경 후 여성의 영양소 섭취 평가

김상연,정경아,장유경 漢陽大學校 韓國生活科學硏究所 2003 韓國 生活 科學 硏究 Vol.- No.21

Women have a greater incidence of coronary heart disease(CHD) after menopause. It relates to hormone imbalance-induced changes in known CHD risk factors, especially hyperlipidemia. Accordingly, once women are diagnosed, the rate of morbidity and mortality is greater than for men. Thus, preventive strategies are critical to improve the quality of life in the later years for women. The purpose of this study was to explore the difference of nutrient intakes and diet quality based on nutrient intake between normocholesterolemia and hypercholesterolemia. The subjects were classified as normocholesterolemia and hypercholesterolemia based on The Guideline for Korean Hyperlipidemia. The semiquantitative food frequency questionnaire was used to measure dietary intakes of the subjects. The results obtained are summarized as follows. Intakes of nutrients such as energy, carbohydrate, protein, fat, minerals and antioxidant vitamins were not significantly different between normocholesterolemia group and hypercholesterolemia group. However, antioxidant vitamins and folate intakes in hypercholesterolemia group tended to be lower than those in normocholesterolmia group. Intakes of vitamin A, vitamin E, and Ca in normocholesterolemia and hypercholesterolemia groups were below RDA. In particular, RDA for those nutrients in hypercholesterolemia was much less than RDA for those nutrients in normocholesterolemia. MAR and INQ in hypercholesterolemia group tended to be lower than those in normocholesterolemia. In particular, INQ of vitamin A was significantly(p<0.05) lower in hypercholesterolemia group than in normocholesterolemia group. These results indicate that it is important to use various diet quality index based on nutrient intake such as % RDA, NAR, MAR, and INQ to explore the relationship between blood cholesterol and nutrient intake. Key words : postmenopausal women, hypercholesterolemia,, % RDA, NAR, MAR, INQ

정신분열병 가계에서 6p24-22 염색체에 대한 연관 분석

박동연,이유상,장용이,조은영,전현옥,박해정,김종원,김창현,이동수,홍경수 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.5

Objectives : Chromosome 6p24-22 has been identified as a disease locus with a high probability for schizophrenia based on several genomewide linkage scans with Caucasian families. The recent association studies suggest that the dysbindin gene located at chromosome 6p22.3 may be a candidate gene of schizophrenia. The purpose of this study was to investigate the linkage of chromosome 6p24.3-22.3 locus to schizophrenia in Korean families. Methods : We recruited one hundred fifty-seven family members from forty-six multiplex schizophrenia families. One hundred three of them were affected individuals. four microsatellite markers with 4.8 cM intervals on 6p24.3-22.3 were genotyped. Non-parametric linkage analysis was performed by evaluating the levels of allele sharing between the affected relative pairs. Results : In the single point analysis, no markers on chromosome 6p24.3-22.3 locus showed statistical evidence for linkage. Significant evidence for linkage was not found in the multi-point analysis. Conclusion : These results do not support the previous evidence from Caucasian families for a locus predisposing to Schizophrenia at 6p24.3-22.3, the locus of dysbindin gene. We conclude that if there is a susceptibility locus for schizophrenia in this region then its effect size is so small as to render our study insufficiently powerful to detect it and schizophrenia susceptibility loci in Korean families likey have different ethnicity-specific effects from Caucasian families.