수확후 채소류에 발생하는 진균독소의 탐색과 방제 (II) 이병된 양념 채소류(양파, 마늘, 고추)에서 주요 진균독소 검출

정일민,주호종,심성철,백수봉,유승헌,Chung, Ill-Min,Ju, Ho-Jong,Sim, Sung-Chur,Paik, Su-Bong,Yu, Seung-Hun 한국분석과학회 1998 분석과학 Vol.11 No.3

수확후 Alternaria, Penicillium 및 Fusarium에 이병된 고추, 양파, 마늘을 HPLC로 주요독소들을 검정한 결과 고추에서 Alternaria 독소의 AOH(alternariol)는 소량~$400{\mu}g/g$, ALT(alternuene)는 소량~$103{\mu}g/g$, TeA(tenuagonic acid)는 $249{\sim}342{\mu}g/g$ 및 AME(alternariol monomethyl ether)는 $206{\sim}294{\mu}g/g$이 검출되었고 양파, 마늘에서 Penicillium 독소의 citrinin이 $2.8{\sim}18.4{\mu}g/g$, penicillin-G는 $0{\sim}439.0{\mu}g/g$, penicillic acid는 $0{\sim}10.2{\mu}g/g$ 및 patulin은 $0{\sim}7.0{\mu}g/g$ 검출되었다. 그리고 양파, 마늘에서 Fusarium 독소로는 fusaric acid가 $0{\sim}553.6{\mu}g/g$ 검출되었을 뿐 deoxynivalenol과 nivalenol은 검출되지 않았다. The major mycotoxins were detected from peppers, onions and garlics infected postharvest pathogens, Alternaria, Penicillium and Fusarium. Analyses of the major mycotoxins were conducted using HPLC. Detected Alternaria mycotoxins per gram of infected postharvest peppers were alternariol (AOH) with amount ranged from small quantity to $440{\mu}g/g$, altenuene (ALT) with amount ranged from small quantity to $103{\mu}g/g$, tenuagonic acid (TeA) with amount ranged from 249 to $342{\mu}g/g$ and alternariol monomethyl ether (AME) with amount ranged from 206 to $294{\mu}g/g$. Penicillium toxins per gram of infected postharvest onions and garlics were citrinin with amount ranged from 2.8 to $18.4{\mu}g/g$, penicillun-G with amount ranged from no detection to $439.0{\mu}g/g$, penicillic acid with amount ranged from no detection to small quantity and patulin with amount ranged from no detection to small quantity. Fusarium toxins per gram of infected postharvest onions and garlics were fusaric acid with amount ranged from no detection to $553.6{\mu}g/g$. However, deoxyrivalenol and nivalenol were not detected from onins and garlics infected by Fusarium.

2000-2001년 서울 북부 지역 홍역 유행의 양상

심민주,정주영,김상우,한태희 인제대학교 백병원 2003 仁濟醫學 Vol.24 No.1

Purpose : To investigate the clinical features of measles outbreak, we studied epidemics of measles during 2000-2001 in northern Seoul district. Materials and Methods : Among 208 patients under 15 years of age who visitied or admitted to our hospital from April. 2000 to February, 2001, we selected 160 patients whose measles IgM antibody was positive. We investigated the age, clinical manifestation, vaccination history, measles IgG antibody. Results : Forty five percent of the patients were under 12 monthes of age, 30.6% were 12-48 months of age and the rest of the patients were over 48 months of age. This epidemic started in April, 2000 and the number of patients increased abruptly in November, reached to peak in December, after then decreased. Fever, cough, and rash were observed in all patients but rhinorrhea in 69%, conjunctivitis in 49%, and Koplik spot in 65.6%. Complication was noted in 74% of patients, and the most common complication was pneumonia(54.4%), followed by gastroenteritis(28%) and acute otitis media and bronchitis. 32.2% of patients had a history of more than one-dose vaccination, and two-dose of vaccination in 12% of patients. Positive rate of Measles IgG antibody was 92% in vaccinated group. Conclusion : Routine vaccination of single measles vaccine and enhancement of revaccination at ages of 4-6 years is necessary to prevent outbreaks when measles are prevalent. More studies are required to investigate the cause of high rate of primary vaccine failure.

영아기 자녀의 발달 수준에 대한 어머니의 지식정확도

심성경,변길희,박주희,박경신,김중근 이화여자대학교 교육과학연구소 2006 교육과학연구 Vol.37 No.3

본 연구는 현재 0~36개월 영아를 양육하고 있는 어머니를 대상으로 0~36개월 영아의 발달 수준에 대한 지식의 정확도를 알아보고 영아 및 어머니의 배경변인에 따른 어머니의 지식 정확도의 차이를 살펴보는 것이다. 연구대상은 전라북도에 거주하는 생후 36개월 이하 영아의 어머니 218명이다. 영아기 자녀의 발달 수준에 대한 어머니의 지식 정확도를 알아보기 위하여 이영석(1998)이 만 2세 이하 영아의 발달수준 조사를 위해 제작한 도구를 사용하였다. 연구 결과 현재 양육하는 영아기 자녀의 발달 수준에 대한 어머니의 지식정확도는 전체와 하위영역 모두에서 50% 내외의 정답율을 보여 낮은 수준의 정확도를 나타냈으며, 1세아 어머니의 경우 0세아와 2세아 어머니에 비해 특히 낮은 지식정확도를 보였다. 또한 영아 및 어머니의 배경변인에 따른 발달 수준에 대한 어머니의 지식 정확도는 차이가 있었다. 즉 0세 어머니의 경우 영아의 출생순위, 어머니의 연령에 따라, 1세아 어머니들은 영아의 성, 어머니의 연령과 학력에 따라, 2세아 어머니의 경우 어머니의 학력에 따라 영아기 자녀의 발달수준 대한 지식정확도에서 유의한 차이를 나타냈다. The purpose of this study is to investigate the mother's accuracy on the knowledge of infant's developmental levels and analyze the differences according to infant gender, birth order, mother's age, education level, and job. The questions for this research are as follows : 1. What is the accuracy of the knowledge of mothers about their infant's developmental levels according to their infant's age? 2. What is difference in accuracy of the knowledge of mothers about their infant's developmental levels according to infant gender, birth order, mother's age, education level, and job? The subject of this study were 218 mothers with infants aged from 0 to 36 months at J and I city in Jeonbuk. The instrument of this study is "The rating scale of knowledge of infant's developmental levels" of Young-suk, Lee(1998). The collected data has been analyzed by mean, SD, percentage, t-test and F-test with SPSS/PC 11.0 Program. The results of this study are summarized as follows : 1. The accuracy of the knowledge of mothers' with their infant's developmental levels is low. Specially, the accuracy of the knowledge of mothers with a 1 year old infant is very low 2. There are differences in the mothers' accuracy of the knowledge about their infant's developmental levels according to infant gender, birth order, mother's age, education level, and job. In the cases of 0 year old infants the mother's accuracy of knowledge showed a difference according to the infant's gender, mother's age, education level, and job. In the case of 1 year old infants the infant birth order, mother's age, and for the 2 year old infant the mother's education level affected the mothers' accuracy of knowledge.

부모와 교사의 유아발달 기대수준

박순이,심성경,박주희 이화여자대학교 사범대학 교육과학연구소 2005 교육과학연구 Vol.36 No.2

본 연구는 유아의 부모와 교사의 유아발달 기대수준을 알아보고, 배경변인에 따른 차이와 어머니-아버지-교사 간 차이를 알아본 것이다. 연구의 대상은 4, 5세 유치원아와 초등학교 1학년생 각 100명씩 총 300명 유아의 아버지와 어머니 300쌍과 담임교사 30명이다. Hess와 Azuma(1981)의 DEQ(Developmental Expectations Questionaire)로 조사한 결과 유아에 대한 부모와 교사의 발달기대수준은 전체적으로 높은 편으로 나타났으며, 배경변인에 따른 차이를 보면 유아의 연령과 교육기관유형에 따라 유의한 차이가 있었다. 즉, 유아의 연령이 증가함에 따라 자녀가 초등학교에 다닐 때 부모와 교사 모두 더 높은 기대수준을 보였다. 아버지- 어머니-교사 간 유아발달 기대수준의 차이를 보면 아버지와 교사 간에는 차이가 없고 어머니의 발달기대수준이 그에 비해 약간 낮은 것으로 나타났다. 배경변인에 따른 아버지-어머니-교사의 발달기대 수준 차이를 보면 유아의 연령과 기관유형에 따라 달랐다. 즉, 아버지와 어머니가 4세와 6세아에 대해 높은 기대수준을 보인 반면 교사는 5세아에 대해 높은 기대수준을 나타냈다. 또한 유치원의 경우는 교사가, 초등학교의 경우는 아버지, 어머니가 더 높은 발달기대수준을 보였다. The main purpose of this study is to investigate the expectation levels of parents and teachers about their children's development. The questions for research are as follows. 1. What is the expectation level of parents and teachers about their children's development? Is there any significant difference in the expectation level of fathers, mothers, and teachers about their children's development according to the background variables? 2. What is the discrepancy among the expectation levels of fathers, mothers, and teachers about their children's development? Is there any significant difference in discrepancies among the expectation level of fathers, mothers, and teachers about their children's development according to the background variables? The subjects of this study were 300 children of 4, 5, and 6 years of age and their parents and 30 teachers from 10 kindergartens and 5 primary schools in K City. The data were collected using DEQ(Developmental Expectation Questionnaire) of Robert D. Hess & Hiroshi Azuma(1981). And the data were analyzed by the statistical methods of M, Sd, t-test, one way ANOVA, with the SPSS/PC Program. The results of this study were summarized as follows; 1. The parents and teachers show high expectation levels about their children's development. They expect their children's early achievements in all the items of developmental tasks. The expectation level of parents about their children's development goes up as children's age. And the parents of primary children show higher expectation levels about their children's development than those of kindergarteners. But The expectation level of teachers about their children's development is highest for the children of age 5, and is higher for the kindergarteners than for primary school children. 2. There is no discrepancy of expectation levels about children's development between fathers and teachers. But the mothers show lower expectation levels about children's development than the fathers and the teachers. There are some significant differences in discrepancies of expectation levels about their children between parents and teachers according to the children's age and a type of educational institution: the fathers and the mothers show much higher expectation level than teachers especially for the children of age 4, 6 and for the kindergarteners.

수확후 채소류에 발생하는 진균독소의 탐색과 방제(Ⅱ) 이병된 양념 채소류(양파, 마늘, 고추)에서 주요 진균독소 검출

정일민,주호종,심성철,백수봉,유승헌 충남대학교 생물공학연구소 1999 생물공학연구지 Vol.7 No.-

수확후 Alternaria, Penicillium 및 Fusarium에 이병된 고추, 양파, 마늘을 HPLC로 주요독소들을 검정한 결과 고추에서 Alternaria 독소의 AOH(alternariol)는 소량∼440㎍/g 및 ALT(altenuene)는 소량∼103㎍/g, TeA(tenuagonic acid)는 249∼342㎍/g 및 AME(alternariol monomethyl ether)는 206∼294㎍/g이 검출되었고 양파, 마늘에서 Penicillium 독소의 citrinin이 2.8∼18.4㎍/g, penicillin-G는 0∼439.0㎍/g, penicillic acid는 0∼10.2㎍/g 및 patulin은 0∼7.0㎍/g 검출되었다. 그리고 양파, 마늘에서 Fusarium 독소로는 fusaric acid가 0∼553.6㎍/g 검출되었을 뿐 deoxynivalenol과 nivalenol은 검출되지 않았다. The major mycotoxins were detected from peppers, onions and garlics infected postharvest pathogens, Alternaria, Penicillium and Fusarium. Analyses of the major mycotoxins were conducted using HPLC. Detected Alternaria mycotoxins per gram of infected postharvest peppers were alternariol (AOH) with amount ranged from small quantity to 440 ㎍/g, altenuene (ALT) with amount ranged from small quantity to 103 ㎍/g, tenuagonic acid (TeA) with amount ranged from 249 to 342 ㎍/g and alternariol monomethyl ether (AME) with amount ranged from 206 to 294 ㎍/g. Penicillium toxins per gram of infected postharvest onions and garlics were citrinin with amount ranged from 2.8 to 18.4 ㎍/g, penicillun-G with amount ranged from no detection to 439.0 ㎍/g, penicillic acid with amount ranged from no detection to small quantity and patulin with amount ranged from no detection to small quantity. Fusarium toxins per gram of infected postharvest onions and garlics were fusaric acid with amount ranged from no detection to 553.6 ㎍/g. However, deoxyrivalenol and nivalenol were not detected from onins and garlics infected by Fusarium.

일부농촌지역의 농약사용실태 및 농약중독 요인 조사

이경민,송주희,장재혁,심수정,강양화,안재경,이숭호,박미영,정문호 대한보건협회 2002 대한보건연구 Vol.28 No.4

Object The usage of agricultural chemical is on the increasing. Use of pesticides has increased agricultural production. However, negative externalities from such use have increased too. Pesticide poisoning is a major public problem. The purpose if this study is to find out the relationship between keeping the safety rules or protective equipments or attending safety education or dose of pesticides use , and poisoning experience. Methods For Gu, H.M. and Pack, S.G. study , we obtained questionnaire data concerning pesticides poisoming. A person interviews on 203 were conducted in two villages in Sinmeari and woulbonri Chunchun , Kangwon province, July 2002. Result 1. 144 people(70.9%) have sprayed pesticides and the rata of experiences of pesticide poisoning was 26% among 144. Spraying time of pesticides was 1-2 hours in 63.9% of farmers. Rate of using the protective equipment was 25.7% (protective clothes), 49.3% (Mask), 48.6 (Gloves), 7.0 (Protective glasses), 64.6% (boots) respectively. 2. Chi-square and multiple logistic regression analysis showed that Duration of spraying per day (<2hr) and using of mask(protective equipment)are significantly association with poisoning experience.(x^2=5.2684 p=0.0217, CI=0.140-0.5853 OR=0.346 p=0.0211 respectively). But no association between poisoning experience and keeping safety rule, attending of safety education. 3. Spraying pesticides. Duration of spraying pesticides, reading manuals and no spraying at fatigue (keeping safety rule) are significantly association with symptom experience(x^2=14.0621 p=0.0002, x^2=7.0639 p=0.0079, CI01.395-10.950 OR=3.908 p=0.0095, CI=0.101-0.726 OR=0.271 0.0094 respectively). But no association between symptom experience and protective equipments, attending of safety education.

Nosocomial empyema caused by a rare serotype, serotype 4c, of Listeria monocytogenes in a patient with rheumatoid arthritis and chronic kidney disease: A case report and review of the literature

Sim, Ju Sung,Kim, Min Ja,Jung, Jae Hyun,Kim, Hwanil,Baek, Seung Hee,Sohn, Jang Wook,Yoon, Young Kyung Elsevier 2015 Journal of infection and chemotherapy Vol.21 No.11

Poster Session : PS 0443 ; Infectious Disease ; Empyema Caused by Listeria Monocytogenes in a Patient with Chronic Kidney Disease: A Case Report

( Ju Sung Sim ),( Min Ja Kim ),( Yong Kyun Yoon ),( Seung Hee Baik ),( Jang Wook Sohn ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Listeria monocytogenes is a gram-positive bacillus, usually presents as meningitis or bacteremia. Although other manifestations such as brain abscess, infective endocarditis, hepatitis have been described, empyema caused by L. monocytogenes is extremely rare. Here, we report a case of empyema due to L. monocytogenes in a patient with chronic kidney disease. Case report: 67-years old woman with chronic kidney disease requiring hemodialysis, has admission due to cough and pleuritic chest pain. Chest radiography revealed pleural effusion and pneumonic infi ltration on right lower lung fi eld. Thoracentesis was performed yielding a yellowish fiuid. Pleural fiuid analysis showed an exudate with a pH of 8.0, white blood cell 3950 /uL, protein 3.0 g/dL, lactate dehydrogenase(LDH) 1983 U/L, in accordance with empyema. As the initial empirical antimicrobial therapy, piperacillin/tazobactam (2.25 g every 8 hours after loading dose) was prescribed. Pleural fi uid cultures grew gram-positive bacilli that were confi rmed to be L. monocytogenes. A molecular approach based on 16S ribosomal, conclusively isolated L. monocytogenes. The isolate was resistant to cefotaxime, but susceptible to ampicillin, ciprofi oxacin, and vancomycin. Antibiotics were changed to ampicillin (2g every 24 hours after loading dose) as the defi nitive antimicrobial therapy. A percutaneous pigtail catheter was also used for drainage. Total 500 cc of pleural fi uid was drained for fi ve days. After 4 days of antibiotics therapy, pleural fi uid cultures were negative. Intravenous ampicillin was administered during fi ve weeks. Follow-up after discharge, showed no recurrence evidence of empyema for 8 months. Conclusion: Our case suggested that L. monocytogenes should be considered in the differential diagnosis as an important pathogen that causes the empyema in an immune- compromised patient.

Predictors of Inadequate Bowel Preparation and Salvage Options on Colonoscopy

Ju Sung Sim,Ja Seol Koo 대한소화기내시경학회 2016 Clinical Endoscopy Vol.49 No.4

Inadequate bowel preparation is observed in more than 25% of all colonoscopies. Identification of predictive factors for inadequate colon cleaning is helpful and more detailed preparation methods should be used for patients at high risk. Age, male sex, inpatient status, and comorbidities were identified as independent risk factors in several previous studies. In patients with insufficient colon preparation, colon irrigation with endoscopic pumps or next-day colonoscopy following further bowel cleaning should be performed. In order to improve the efficacy and safety of both bowel preparation and colonoscopy, the endoscopic team should identify the patient’s medical conditions and choose the optimal bowel preparation agent and regimen.

갯기름나물 중 Ethoprophos와 Metaldehyde의 잔류 특성

심주연 ( Ju Yeon Sim ),조성용 ( Sung Yong Jo ),김용범 ( Yong Beom Kim ),황준혁 ( Jun Hyuk Hwang ),강은옥 ( Eun Ok Kang ),경기성 ( Kee Sung Kyung ) 한국환경농학회 2020 한국환경농학회 학술대회집 Vol.2020 No.-

This study was carried out to investigate the residual characteristics of insecticide ethoprophos and metaldehyde in coastal hogfennel under greenhouse conditions. The test commercial pesticides, ethoprophos 5% GR and metaldehyde 6% GR were treated onto upland soil surface at the recommended and double dose before planting and then the test crop was transplanted. Sampling was done on the pre-harvest day of 50 days after treatment. To investigate residue change after harvest, additional samples were also collected 7 and 14 days after harvest. Limits of quantitation of ethoprophos and metaldehyde in the crop were all 0.01 mg/kg. Recoveries of ethoprophos and metaldehyde were ranged from 101.8 to 110.2% and from 71.1 to 93.0%, respectively. The residues of ethoprophos in the crop collected at harvest in recommended dose and double dose plots were 0.42 and 0.61 mg/kg, respectively. In case of metaldehyde, those were 0.25 and 1.37 mg/kg, respectively. Also, residues in the test crop collected 7 and 14 days after harvest found to be decreased comparing to those in the crop at harvest. The dissipation rates of the test pesticides in the crop collected 7 and 14 days after harvest were from 60.7 to 61.9% and from 51.1 to 56.0%, respectively, in both recommended and double dose.