국내 의료종사자에서 HHV-8의 항체양성률에 대한 연구

주우철,최용준,박재은,이혜명,이진수,정문현,김수미,문지혜 대한감염학회 2008 감염과 화학요법 Vol.40 No.4

HHV-8 virus is known to be associated with Kaposi's sarcoma (KS) in HIV seropositive patients and its seroprevalence has geographic difference, In South Korea, incidence of KS is low not only in general population but also in HIV patients compared to other countries, It is speculated that low seroprevalence of HHV-8 has contributed to the low incidence of KS in South Korea. We examined the seroprevalence of anti HHV-8 IgG of HIV seronegative health care workers in one University hospital. Enzyme-linked immunosorbent assay(ELISA) was used for diagnosis. One person (0.6% 1/164) was seropositive, six were equivocal (3.7%,6/164) and 157 people were seronegative (95.73%, 157/164). This study revealed that seroprevalence of HHV-8 in general population was. low in South Korea. Further studies are needed to be carried out to evaluate the low HHV-8 seroprevalence in Korea.

Determination of the optimum porosity for 2‑CEES adsorption by activated carbon fiber from various precursors

Hye‑Min Lee,Byeong‑Hoon Lee,Ju‑Hwan Kim,Kay‑Hyeok An,Soo‑Jin Park,Byung‑Joo Kim 한국탄소학회 2019 Carbon Letters Vol.29 No.6

In this study, we prepared ACFs with a high specific surface area from various precursors (rayon, pitch, and oxidized polyacrylonitrile-based fibers) by a steam-activation technique and investigated the effects of the micropore and mesopore fraction on 2-CEES adsorption behaviors. The activation time was precisely controlled so that the activation yield was in the range of 35–40% to ensure the mechanical properties of the ACFs. The N2 adsorption isotherm characteristics at 77K were confirmed by Brunauer–Emmett–Teller, Barrett–Joyner–Halenda and non-local density functional theory equations. The adsorption capacities of the ACF were measured by breakthrough experiments in the gas phase (750 μg/mL of 2-CEES in N2 flow). The removal efficiency of the ACFs was evaluated and compared with that of AC. From the results, specific surface areas and total pore volume of the ACF were determined to be 1380–1670 m2/g and 0.61–0.82 cm3/g, respectively. It was also observed that various pore characteristics of ACF were found to be dependent on crystallite structure of each precursor. The break through time (C/C0 = 0.10) was in the order of Oxi-Pan-H-9-2 < Saratoga AC < Rayon-H-9-3 < Pitch-H-9-4. This indicates that 2-CEES adsorption capacity could be a function not only of specific surface area or total pore volume, but also of sub-mesopore volume fraction in the range of 1.5–2.5 nm of adsorbents.

관상동맥심질환에 대한 항고혈압제의 효능평가를 위한 메타분석

구혜원,정귀옥,김대성,손대원,박병주 大韓臨床藥理學會 2000 臨床藥理學會誌 Vol.8 No.1

혼합미셀 형성에 의한 베타카로틴의 가용화

박원봉,문유선,권영주,주혜진 서울여자대학교 자연과학연구소 2003 자연과학연구논문집 Vol.15 No.-

베타카로틴의 물에 대한 용해도는 담즙산염의 임계미셀농도에서 급속히 증가하였으며, 혼합미셀을 형성시 용해도가 더욱 우수하였다. 또한, 베타카로틴을 수용화 하는데 필요한 계면활성제의 최적비율은 1:5이며, 글리세롤, 레시틴, STPP, 젤라틴, 카라기난 등 각종 안정화제를 적절한 비율로 첨가하여 업자크기를 측정한 결과, 0.48 μm 의 안정된 혼합미셀 조성불을 얻을 수 있었으며, 이 조성불은 항산화활성이 거의 그대로 유지됨을 알수 있었다. β-Carotene is a member of hydrophobic pigments known as carotenoids, which are responsible for the bright warm colors in some fruits and vegetables, β-Carotene is an important antioxidant which protects the body from free radicals. The body converts β-carotene, a nontoxic vitamin A precursor, to vitamin A as needed. Dissolution in surfactant solutions above the critical micelle concentration offers one approach to the formation of poorly soluble materials in solution form. In the present study, the β-Carotene was dissolved in mixed micelles of bile salts (sodium cholate and sodium deoxycholate). Water-solubility of β-Carotene was estimated by measuring absorbance and phase diagram of water/β-Carotene/bile salts system was plotted. Effects of stabilizer on the stability of soluble β-Carotene was estimated by measuring the size of mixed micelles containing β -carotene. Antioxidative activity of hydrophobic and aqueous β-Carotene was estimated by measuring TBA value of linoleic acid emulsion incubated with anti oxidative components.

대학생을 위한 리더십향상 집단상담 구안 및 효과 연구

박현주,김민정,임진,엄혜련 西江大學校 學生生活相談硏究所 2005 人間理解 Vol.26 No.-

현대사회에서의 리더십은 크게 셀프리더십, 팔로워십, 능력부여리더십, 서번트리더십으로 분류될 수 있다. 한국의 대학생은 향후 인생의 목표를 설정하고 계획하여 추진하고 더불어 공동체의 일원으로 서로 교류하고 성장 한다는 발달적 과제를 가지고 있다. 따라서 대학생의 리더십은 셀프리더십을 바탕으로 한 자기관리, 대인관계 관리, 공동체 참여로 구성된다. 본 연구에서는 대학생의 리더십을 향상시키기 위한 집단상담을 구안하였으며 구조화된 대학생 리더십향상 집단상담을 2005년 1월에 실시하였다. 참여한 총 10명의 집단원들을 대상으로 집단상담 전 후에 각 구성요소를 측정하는 설문조사를 실시하였으며, 통계적으로 유의미한 차이는 아니었으나 자기관리, 대인관계관리, 공동체참여 각 영역 모두에서 향상된 양상을 보였다. 또한 집단원들의 회기별 피드백을 토대로 본 프로그램의 효과를 검증하였으며 본 프로그램의 보다 효과적인 적용을 위한 논의를 덧붙였다. Leadership, nowadays, can be classified into four different kinds: self-leadership, followership, empowering-leadership, and servant leadership. Korean university students have developmental tasks as members of group such as setting a life goal, making a plan, making an action, associating with others, and being advanced. Therefore, the elements of leadership program for university students based on self-leadership are self management, interpersonal relationship management, and participating in a group. In this study, a structured program for developing leadership of university students was designed, and operated on Jan, 2005. Surveys which measured each elements of the program were given to ten students who were participated in a group before and after the program. A statistical result was not significant. However, each elements, self management, interpersonal relationship management, and participating in a group, showed a progress. Session reviews by students were also used to verify the effect of the program. Further suggestions and studies for more effective application of the program were discussed.

글로벌 소싱 기지로서의 한국 섬유·의류산업의 현황

박혜정,이영주,임숙자 한국의류학회 2003 한국의류학회지 Vol.27 No.7

Korea is facing great threat form other countries as a major global sourcing site for textile and apparel products. The threat has been augmented by changes in external environment such as advents of Trading Blocs and Free Trade Area(FTA) as well as internal environment such as hikes in labor cost and lack of flexibility in accommodating international buyers' needs. This study analyzed international buyers' sourcing activities in Korea for purpose of developing strategies to enhance competitiveness of the Korean textile and apparel industries in the global market. The data used in this study were gathered by surveying 52 non-Korea textile and apparel product buyers with cooperation of the Korea Federation of Textile Industries (KOFOTI). The data were analyzed by mean, frequency, Pearson correlation coefficient, and x²analysis. The results indicated that Korea is still attractive to many international buyers expecially to those who have been engaged in global sourcing for longer periods of time with bigger purchasing budgets. However, in order to expand and solidify their customer bases, Korean companies should focus more on developing competitively priced value added products a step ahead of their foreign competitors, diversifying their marketing channels including Internet.

Rhodospirillum rubrum DM에 의한 δ-Aminolevulinic Acid의 최적생성조건

이혜주,이진숙,박인호 東亞大學校附設基礎科學硏究所 1998 基礎科學硏究論文集 Vol.15 No.1

본 실험실에서 분리하여 Rhodospirillum rubrum DM으로 동정된 균주는 빛이 존재하는 혐기적인 조건에서 ALA의 균체외 방출량이 높게 나타났고, ALA의 균체외 방출량은 균주가 정지기에 접어들어도 120시간 까지 계속적인 증가를 보였다. ALAD의 저해제인 Levulinic acid를 15 mM첨가했을 때가 5 mM, 30 mM을 첨가했을 때 보다 ALA의 균체외 방출량이 높았다. 또한 LA의 첨가는 대수기의 초기(약 16시간)에 첨가하는 것이 성장도 억제되지 않고 ALA의 균체외 방출량 또한 18 mM 로, 성장 후기에 첨가하는 것(3-4 mM)보다 높게 나타났다. Rhodospirillum rubrum DM, isolated and identified in our laboratory, produces higher amount of ALA under anaerobic-light condition in Lascelles medium than other three culture conditions such as aerobic-light, aerobic-dark, anaerobic-dark conditions. Though cells approached stationary phase, the accumulation of ALA increased continuously until 120 hr after inoculation. ALA production was higher when 15 mM of levulinic acid(LA), inhibitor of ALAD, was added into culture broth than 5 mM or 30 mM of LA. When LA was added at the early exponential phase(16 hr), the cell mass was not inhibited by LA, and then, amount of ALA was reached the maximum(18 mM). When LA was added at the late exponential phase, the production of ALA was 3-4 mM. As a result, adding time of LA to the culture broth for the production of extracellular ALA was added at the early exponential phase.

패턴 Top Rounding 효과를 고려한 패턴 붕괴 전산모사

이형주,박준택,오혜근 한양대학교 이학기술연구소 2002 이학기술연구지 Vol.5 No.-

패턴의 선폭이 100 nm 이하로 작아짐에 따라 발생하는 패턴의 붕괴 현상은 반도체생산과 수율에 많은 영향을 미친다. 패턴 붕괴 현상은 리소그래피 과정 중 현상 후 세척액을 건조하는 과정에서 주로 발생하며 세척액의 표면장력에 의한 모세관 현상이 주된 원인으로 알려져 있다. 패턴 붕괴 현상을 시뮬레이션하기 위하여 패턴이 세척액에 외해서 균일한 압력을 받을 때와 집중 압력을 받을 때의 역학적 모델을 세우고 각각의 모델을 통하여 선폭과 패턴간의 거리에 따른 임계 높이/선폭비 (aspect ratio)를 계산하여 실제 실험 결과와 일치하는 모델을 선정하였다. 시뮬레이션 결과 패턴의 top 부분이 둥근 (rounded top) 패턴이 각진 (flat p) 패턴에 비해 변형이 줄어들 수 있다는 것을 확인할 수 있었다. The pattern size is reduced as the device is more integrated. The resist deformation phenomenon has been a serious problem under 100 nm line width pattems. The most applicable model for an existing empirical result is chosen to create a simulation tool by comparing the two mechanical models when a pattern receives a distributed pressure or a concentrated pressure from the rinse liquid. Based on the chosen model, the critical aspect ratio with respect to line width and space can be calculated. The simulated results show that the pattern collapse phenomenon is reduced for a rounded top resist profile rather than for aflat top profile

Stroke에서 감압적 개두술, 정위적 조직 생검과 병리적 소견 고찰 : 중증 제뇌탈출을 동반한 초급성 뇌경색과 신경교종 내 출혈 감별 To differentiate the Herniated hyperacute Cerebral Infarction from the Glioma bleeding

이주용,조준,박호권,장상근,문창택,한혜승,이경룡 건국대학교 의과학연구소 2004 건국의과학학술지 Vol.14 No.-

The authors in this manuscript aimed to provide a practical importance of the differential diagnosis of intracranial brain tumor with emphasis on non-neoplastic abnormalities such as cytotoxic edema of the penumbra zone in strokes. The well known SOLs are cerebral ischemic, inflammatory and dysplastic lesions, which intraaxially imitate glioma and other neurogenic tumors. Brain tumor is the one of common intracranial space-occupying lesions (SOLs) on the diagnostic images. However, many non-neoplastic lesions may be indistinguishable from tumors. Especially, early mortality used to be caused by space-occupying hyperacute ischemic stroke, brain edema and herniations. For the retrospective analysis, the authors reviewed the patient charts, the emergency brain Computerized Tomography (CT), magnetic resonance imaging (MRI), clinical stroke history. From Jan. 2003 to Dec. 2003, we managed total 61 acute strokes in ICU. Even though we operated six decompressive craniotomies, nine stereotactic craniotomies including two procedures of brain biopsy and three extraventricular drainage procedures, three patients (4.91%) were finally expired out from the induced herniation and medullary failure by those aggressive strokes. 43 patients (70.5%) were recovered good from stroke attack. 15 patients (24.6%) were improved with residual neurologic deficits. In conclusion, aside from growing efforts of the radiologist to make the early diagnostic impression, the authors suggest that urgent neurosurgical explorations with the pathologic diagnostic decision should be requested to decrease the fatality.

인라인 스케이트 이용자들의 손상 유형과 위험 요인

서혜경,문지영,성주욱,김말영,이준호,박정이,차성화,백나영,이재민,김수민,임현술,정해관,배근량,정철 東國大學校醫學硏究所 2004 東國醫學 Vol.11 No.2

지난 몇 년 사이 인라인 스케이트는 젊은층을 중심으로 인기있는 스포츠가 되었으며 이러한 대중화와 더불어 인라인 스케이트와 관련된 사고 빈도도 증가하는 추세이다. 따라서 본 연구는 인라인 스케이트 이용에 따른 사고율과 이용습관 형태, 손상 유형 및 위험 요인을 알아보고자 시행되었다. 2003년 9월 14일부터 9월 24일까지 경주시 ○○초등학교 6학년, ○○중학교 1학년, ○○여자고등학교 1학년, ○○고등학교 1학년, 동국대학교 의과대학 의학과 학생, 경주황성·포항 해맞이 공원의 성인을 포함한 총설문 대상자 1,305명 중 인라인 스케이트 이용자 392명을 대상으로 단면 연구를 수행하였다. 조사에 앞서 병원 방문과 사전 조사를 시행 하였으며 자기 기입식 설문지를 통해 정보를 수집하였다. 초, 중, 고 인라인 스케이트 전체 이용률은 28.1% 사고율은 30.1%로 나왔으며 주로 젊은층에서 사고가 많았으며 나이가 증가할수록 빈도가 증가하였다. 보호 장비 착용률은 44.4%로 조사되었다. 손상 부위로는 무릎과 상지 부위가 많은 것으로 조사되었으며 손상 유형은 찰과상과 타박상이 많았다. 스케이트를 타기 시작한지 1개월 이내에서 사고를 가장 많이 당한 것으로 나타났다. 전체 부상자의 20%가 후유증이 있었던 것으로 나타났다. 본 연구에서 인라인 스케이트 이용자들의 사고율이 비교적 높음을 알 수 있었다. 손상 부위의 무릎 및 상지 집중 현상으로 인해 무릎과 상지 부위의 보호대 착용이 필요할 것으로 생각되며 또한 사고를 줄이기 위해 초기 기술 습득 단계부터 전문가를 통한 체계적 교육과 안전 의식 고양이 필요할 것으로 보인다. In the past several years, Inline skating has become a popular sport among young people. With popularization of Inline skating, the number of injuries has increased proportionately. The purpose of this study is to evaluate the prevalence of injuries, the behaviors of skating, the nature and risk factors of injuries. We conducted a questionnaire an 1,305 subjects from Sep. 14 to 24, 2003. The Inline skaters were 392. These participation were mainly students from ○○elementary school, ○○middle school, ○○women's high school, ○○high school, Dongguk medical school, and adult skaters in several parks. The prevalence of injuries were 30.1%. Injuries were predominant from younger age and frequencies were increased according to increasing age. The most common location of injuries were both knee and the upper extremities. Most of injury type were skin abrasion and contusion. Injuries were highest within one month after First skating. 20% of injuries experienced a sequela. The results of this study show the severity of Inline skating-related injuries. We expect that the knee and the upper extrimities protectors should be used adequatly. Also to reduce injuries, when the skills are obtainded, the specilized learning programs and safety awareness are needed.