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정지아,서고은,송준호,박상준,Jeong, Ji-A,Seo, Go-Eun,Song, Jun-Ho,Park, Sang-Jun 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.1
Plasma cell myeloma is malignant disease of plasma cell in the bone marrow. Myeloma accounts for about 1% of all cancers. The solitary plasma cellmyeloma is rare tumors and account for less than 10% of plasma cell neoplasm. It is often progress to multiple myeloma at 30-40% despite successful local treatment with surgery and radiation therapy. We are reporting a case of solitary plasma cell myeloma on anterior maxillary region that developed after kidney transplantation and immunosuppressive therapy.
정지아 ( Ji A Jeong ),한수경 ( Suk Yeon Han ),홍외생 ( Oi Saeng Hong ),김미자 ( Mi Ja Kim ) 국군간호사관학교 군진간호연구소 2013 군진간호연구 Vol.31 No.2
This study was conducted to describe the Hearing Threshold of Limits(HTLs) among the ROKAF pilots and to analyse the associations between the HTLs and the contributing factors. Methods : The sample was composed of 427 pilots taking the physical examination in Aerospace Medical Center. A structured questionnaire and physical examination data were used and collected date were processed using SPSS 18.0 win. Results : The pilots experience greater Hearing loss with increasing severities from Lower Frequencies(0.5,1,2kHz) to Higher Frequencies(3,4,6kHz). HTLs of left ear is higher than right ear. Age and past history were the risk factors in both ears. Additional risk factors were tinnitus for the left ear Lower Frequencies and blood sugar fasting for the Higher Frequencies. Conclusion : Based on the results of this study, the Pilots need to take a special care to prevent the hearing loss. Above all, as Aerospace Medical Center is the "Hub" for flight crew, it needs to develop the health promotion programs related to hearing loss for pilots.
Development of New Vector Systems as Genetic Tools Applicable to Mycobacteria
Ji-A Jeong(정지아),Ha-Na Lee(이하나),In-Jeong Ko(고인정),Jeong-Il Oh(오정일) 한국생명과학회 2013 생명과학회지 Vol.23 No.2
Mycobacterium 속은 Mycobacterium tuberculosis, Mycobacterium leprae, Mycobacterium bovis와 같은 동물과 인체에 병원성을 나타내는 세균 종을 다수 포함하고 있다. 이들의 숙주에서의 생존과 병원성에 관한 유전학적 정보를 확보하는 것은 매우 중요하지만, 효과적인 유전학적 도구가 부족하였기 때문에 이들에 관한 연구가 미비하였다. 따라서 mycobacteria의 연구를 위한 분자생물학적 실험 도구로서 다양한 기능성 vector들이 고안되었고, 이러한 기능성 vector의 개발은 실질적으로 mycobacteria에서의 연구 효과를 증진시켰다. 본 연구에서는 Mycobacterium smegmatis에 적용 가능하고 기존에 제시되었던 mycobacteria 연구에 있어서의 한계점을 극복하기 위한 노력의 일환으로, 기능성 vector인 temperature-sensitive replication origin (TSRO)과 counterselectable marker로 levansucrase를 암호화하는 sacB 유전자를 포함하는 suicide vector pKOTs, chromosomal DNA로 site-specific recombination을 통해 삽입되는 lacZ transcriptional fusion vector pMV306lacZ, 그리고 TSRO를 가지는 minitransposon vector pTnMod-OKmTs를 개발하였다. 이 vector들은 실질적으로 M. smegmatis에서 효과적으로 작동하는 것이 확인되었으며 목적으로 하는 실험 결과 도출 가능성 또한 보여주었다. 따라서 이들 vector는 앞으로의 mycobacteria에 대한 효과적인 연구 기반이 될 것으로 기대된다. The genus Mycobacterium includes crucial animal and human pathogens such as Mycobacterium tuberculosis, Mycobacterium leprae, and Mycobacterium bovis. Although it is important to understand the genetic basis for their virulence and persistence in host, genetic analysis in mycobacteria was hampered by a lack of sufficient genetic tools. Therefore, many functional vectors as molecular genetic tools have been designed for understanding mycobacterial biology, and the application of these tools to mycobacteria has accelerated the study of mechanisms involved in virulence and gene expression. To overcome the pre-existing problems in genetic manipulation of mycobacteria, this paper reports new vector systems as effective genetic tools in Mycobacterium smegmatis. Three vectors were developed; pKOTs is a suicide vector for mutagenesis containing a temperature-sensitive replication origin (TSRO) and the sacB gene encoding levansucrase as a counterselectable marker. pMV306lacZ is an integrative lacZ transcriptional fusion vector that can be inserted into chromosomal DNA by site-specific recombination. pTnMod-OKmTs is a minitransposon vector harboring the TSRO that can be used in random mutagenesis. It was demonstrated in this study that these vectors effectively worked in M. smegmatis. The vector systems reported here are expected to successfully applicable to future research of mycobacterial molecular genetics.
심와부 복통으로 내원한 5세 소아에서의 위 선근종 1례
허미영,정지아,최금자,성순희,서정완,Heo, Mi-Young,Jung, Ji-A,Choi, Kum-Ja,Sung, Sun-Hee,Seo, Jeong-Wan 대한소아소화기영양학회 2001 Pediatric gastroenterology, hepatology & nutrition Vol.4 No.1
심한 심와부 동통과 구토를 주소로 내원한 5세여아에서 상부 위장관 내시경으로 위유문동에서 중심요와를 보이는 비정상적인 주름을 관찰하였다. 복통이 계속되어 이소성췌장으로 생각하고 위부분절제술을 시행하여 치료한 위 선근종 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Adenomyomas of the stomach are rare tumors characterised by duct/gland-like structures embedded within a smooth muscle stroma. A 5-year-old female patient was admitted to the department of Pediatrics, Ewha Womans University MokDong Hospital with the history of severe epigastric pain and vomiting for 1 day. Esophagogastroduodenoscopy showed bridging fold with central dimpling on posterior wall of prepyloric antrum. Endoscopic biopsy was nondiagnostic. The patient complained epigastric pain continuously and underwent wedge resection. Pathologic examination showed an adenomyoma of the prepyloric antrum. After wedge resection, the patient did not complain epigastric pain during the postoperative follow-up. We report an unusual case of an adenomyoma of stomach.
IP 네트워크 기반의 VOD를 위한 QoS 아키텍처의 설계
정지아(Ji-A Chung),김정원(Jeong-Won Kim),김종현(Jong-Hyun Kim),정기동(Ki-Dong Chung) 한국정보과학회 1999 한국정보과학회 학술발표논문집 Vol.26 No.1A
본 논문에서는 주문형 비디오(VOD : Video On Demand) 시스템이 사용자에게 제공하는 다양한 선택과 보장에 초점을 두는 QoS 아키텍처를 제안한다. 제안한 QoS 아키텍처에서는 IP 네트웍에 기반을 둔 호스트 단위로 확장 가능한 VOD 시스템(SVOD : Scalable VOD)상에서 MPEG-2의 스케일러빌리티를 이용하여 QoS의 다양성을 제공하고, IP 네트워크의 자원예약 프로토콜인 RSVP(Resource Reservation Protocol)를 이용하여 클라이언트 기반의 QoS를 요구 보장이 가능하다. 또한 사용자 QoS 파라메터를 네트워크 및 VOD 서버 자원으로 변환하는 메커니즘을 제공한다.
배상영,박선주,남승연,정지아,서정완,이선화,Bae, Sang-Young,Park, Sun-Joo,Nam, Seung-Yeon,Jung, Ji-A,Seo, Jeong-Wan,Lee, Sun-Wha 대한소아소화기영양학회 1999 Pediatric gastroenterology, hepatology & nutrition Vol.2 No.2
저자들은 심한 빈혈과 복통을 주소로 내원한 폐결핵을 동반하지 않은 9세 여아에서 시행한 대장내시경 소견과 생검 조직의 배양 검사로 진단하고 항결핵제 치료로 증상이 호전된 예를 경험하여 보고하는 바이다. Childhood intestinal tuberculosis is difficult to diagnose for its protean clinical manifestations, especially in cases without pulmonary involvement. Differential diagnosis with Crohn's disease, inflammatory bowel disease and other malignancy is also important. Surgery has often been required for pathologic confirmation or therapy. Colonoscopy may be performed safely under consciousness sedation in children for bacteriologic and histopathologic confirmation of the biopsy specimen in addition to gross appearance of the lesion. We have experienced a case of intestinal tuberculosis presenting with chronic abdominal pain, diarrhea, weight loss and anemia in a 9 year old girl who was diagnosed by a colonoscopic examination and culture of the biopsy specimen from the ascending colon. The patient was managed with antituberculous drugs and recovered uneventfully.
조세지,김종완,김하영,오상익,정소정,정지아,조아라,이명헌,조호성,변재원,Cho, Se-Ji,Kim, Jong Wan,Kim, Ha-Young,Oh, Sang-Ik,Jeong, So Jeong,Jung, Ji-A,Cho, Ara,Lee, Myoung-Heon,Cho, Ho-Seong,Byun, Jae-Won 대한수의학회 2015 大韓獸醫學會誌 Vol.55 No.1
Brachyspira (B.) hyodysenteriae is a causative agent of swine dysentery that is responsible for death and economic losses in the pig industry. It is imperative that clinical samples be delivered fresh for accurate diagnosis. The viability and DNA detection of B. hyodysenteriae using lab-made (phosphate buffered saline and modified tryptic soy broth) or commercial transport media (C, D, and E) were compared by culturing and real-time PCR at $4^{\circ}C$ or room temperature (RT), respectively. B. hyodysenteriae grown in D (Anaerobe Systems, USA) and E (Starplex Scientific, Canada) media was viable for 4 days at $4^{\circ}C$ and RT. However, B. hyodysenteriae in A, B, and C (culture swab; BD Biosciences, USA) media were not recovered after 2 days at RT. Ct values for real-time PCR at $4^{\circ}C$ and RT ranged from $27.2{\pm}2.1$ (C) to $29.6{\pm}0.5$ (B), and $28.0{\pm}0.9$ (E) to $30.2{\pm}1.5$ (B), respectively. Considering the field conditions, it is important that transport media is used for specimen isolation and PCR to obtain an accurate diagnosis of swine dysentery.
서고은,정지아,송준호,정태영,이수운,박상준,Seo, Go-Eun,Jeong, Ji-A,Song, Jun-Ho,Jeong, Tae-Yeong,Lee, Soo-Woon,Park, Sang-Jun 대한악안면성형재건외과학회 2010 Maxillofacial Plastic Reconstructive Surgery Vol.32 No.1
Oral metastatic tumors are uncommon and account for about 1% of malignant oral neoplasm. The metastatic lesions are common in breast, lung, kidney and thyroid cancer. About 20% of oral mucosal metastasis is founded before detection of primary lesions. Usually, the metastatic lesions of the oral cavity are involved in the jaw bone, especially mandible more than the oral soft tissues. We report a case diagnosed as the stomach cancer with mandible metastatic lesion looking like TMJ abscess.