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신진우,조우승,조성빈,김재훈,정지은,사예지,백경동,박동규 순천향대학교 부설 산업기술연구소 2021 순천향 산업기술연구소논문집 Vol.27 No.2
As modern people's interest in health grows, wearable healthcare-related technologies that can collect biometric information and receive health-related services regardless of time and place are developing. This paper proposes the healthcare system based on voice recognition function. Unlike conventional wearable healthcare systems, the proposed system provides real-time telemedicine and diagnosis and the direct connection with doctors is possible through it. And almost all functions of the application in it are operated with voice commands to lower user access barriers. Because it deals with personal information including medical information, encryption algorithms have been applied between all data movements. Finally, the healthcare system proposed in this paper is expected to increase convenience in health care and reduce the medical gap.
후천성 면역 결핍증에서의 폐렴구균 감염 부검 1예 : An Autopsy Report
이미숙,우준희,진소영,김종원,최창현,김양수,김은옥,김백남,이동화,류지소 대한감염학회 1996 감염 Vol.28 No.3
28세 남자의 후천성 면역 결핍증 환자에서 S. pneumoniae 폐렴이 합병되어 사망한 1예를 경험하여 부검소견과 함께 보고하는 바이다. Pulmonary infections such as Pneumocystis carinii, cytomegalovirus, and tuberculosis are a major cause of morbidity and mortality in patients with human immunodeficiency virus(HIV) infection. Patients with HIV infection are at increased risk for bacterial pneumonia in addition to opportunistic infection. Although in a primary defect, HIV infection is associated with substantial dysfunction of humoral immunity, which predisposes patients to bacterial infections, particularly with encapsulated organisms, such as Streptococcus pneumoniae. We report a case of 28 year-old Korean male with HIV infection who died of respiratory failure due to pneumococcal pneumonia with autopsy findings.
노인 인구에서 신경인지기능저하와 혈청 지질농도와의 상관성
유영선,최석주,정성수,김지은,윤성욱,전동욱,백준형,박성우,이정구,추일한,김영훈 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.6
Objectives : In this study, the authors evaluated the correlation between eurocognitive impairments and serum lipids levels among Korean elderly over the age of 65. Methods : A total of 609 elderly individuals participated in this study. Screening for cognitive impairments were carried out using the Mini-Mental Status Examination-Korean version (MMSE-KC). There were 197 subjects above 1.5SD Of MMSE- KC and they were evaluated using the Korean versions of the Consortium to Establish a Registry for Alzheimer's Disease (AD) (CERAD-KC) and Geriatric Depression Scale (GDS-K). Results : There was a correlation between old age/low levels of education and AD (p<0.05, P<0.01). There was an inverse correlation between the serum level of total cholesterol and the word list recognition test scores. The serum levels of LDL cholesterol were inversely correlated with the scores on the constructional praxis test, word list recall test and word list recognition test. Inverse correlations between the serum level of triglyceride and scores on the word list recall test and word list recognition test were also observed. Conclusion : There were inverse correlations between the serum levels of lipids and language/memory function in subjects with AD.
이정은,함효주,이관용,노지웅,유진석,정우백 이화여자대학교 의과학연구소 2014 EMJ (Ewha medical journal) Vol.37 No.2
Early repolarization is a common electrocardiographic (ECG) feature found in young adults, men and athletes, and has been considered to be a benign feature for the last several decades. But recent studies suggest that early repolarization may be related to idiopathic ventricular fibrillation and sudden cardiac death. We report a young man, 35 years old, who had life threatening ventricular fibrillation and sudden cardiac arrest. He was evaluated for cardiac causes of ventricular fibrillation. There was no explanation other than that his ECG showed an early repolarization pattern so we treated him with implantable cardioverter defibrillator. Thus, we suggest that early repolarization may be related with life threatening ventricular arrhythmia.
Anti-obesity Effect of Centella asiatica Hot-Water Extract in 3T3-L1 Preadipocytes
Ji-Woo Hong,Ha-Young Park,Han-A Kim,Dong-Ho Baek,Jin-Woo Kim 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
The present study investigated the anti-oxidant and anti-obesity effects of Centella asiatica hot-water extract. Total polyphenol content (TPC) and radical scavenging activity (RSA), which are antioxidant indices, were 14.4±0.67 mg GAE/g DM and 82.6±0.31%, respectively, and lipase activity inhibitory (LAI) of an anti-obesity index was 68.1± 0.90%, indicating anti-oxidant and anti-obesity effects. Reverse transcription-polymerase chain reaction (RT-PCR) analyses of sterol regulatory element binding proteins-1c (SREBP-1c), peroxisome proliferator activated receptor-γ (PPAR-γ), and fatty acid synthase (FAS) were done with 3T3-L1 cells to investigate the anti-obesity effect. C. asiatica hot-water extract had no cytotoxic and reduced the accumulation of lipid droplets in 3T3-L1 preadipocytes. In addition, the expression of SREBP-1c, PPAR-γ, and FAS involved in 3T3-L1 differentiation significantly decreased (p<0.05). This study demonstrated that C. asiatica hot-water extract can be used as anti-oxidant and anti-obesity agents in functional foods and medicines.
Seung-Woo Son,Jung Ho Park,Ji-Min Baek,Do-Kwyn Kim,Seung Ryul Lee,Sang-Moon Lee,Jieon Yoon,Jungtaek Kim,Woo-Bin Song,Sunjung Kim,Dong Suk Shin,Yihwan Kim,Seung Heon Shin,Tae-Woo Kim,Jung-Hee Lee,Dae-H IEEE 2017 IEEE electron device letters Vol.38 No.6
<P>In this letter, we have investigated the properties of In0.53Ga0.47As quantum-well (QW) metal-oxide-semiconductor field-effect-transistors (MOSFETs) on a 300-mm(100) Si wafer. We have explored the impact of scaling down In0.53Ga0.47As channel thickness (t(ch)) from 15 to 5 nm. The fabricated devices show excellent electrostatic integrity, such as subthreshold-swing (SS) < 80 mV/decade and drain-induced barrier-lower (DIBL) < 20 mV/V. Furthermore, we have extracted the effective mobility (mu(n_eff)) of the fabricated devices to investigate the carrier transport properties of the InGaAs MOSFETs with different values of t(ch). The device with t(ch) = 15 nm displayed a value of mu(n_eff) = 2, 190 cm(2)/V-s at room temperature. This value was found to decrease as tch was scaled down.</P>
Isolation of Sterols from Cowpea (Vigna sinensis) Seeds and Their Promotion Activity on HO-1
( En Ji Cui ),( Ji Hae Park ),( Hee Jung Park ),( In Sik Chung ),( Ji Young Kim ),( Seung Woo Yeon ),( Nam In Baek ) 한국응용생명화학회 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.3
Cowpea (Vigna sinensis K.) seeds were extracted with 80% aqueous methanol. Concentrated extracts were partitioned with ethyl acetate, butanol, and H2O, successively. The repeated silica gel and octadecyl silica gel (ODS) column chromatographic separations for the butanol fraction led to isolation of four sterols, whose chemical structures were determined as 7β-hydroxysitosterol (1), 7α-hydroxysitosterol (2), 7-ketositosterol (3), and stigmasterol 3-O-β -D-glucopyranoside (4) from the interpretation of spectroscopic data including NMR, mass spectroscopy, and infrared spectroscopy (IR). This paper reports the first isolation of compounds 1 and 2 from V. sinensis seeds. All compounds were evaluated for the effect on heme oxygenase-1 (HO-1) expression, which is considered to be an antioxidant enzyme that catabolizes heme into carbon monoxide, free iron, and biliverdin. All sterols increased the expression of HO-1 in HepG2 cells.