TSC 합성보의 제작방법에 따른 구조적 거동에 관한 실험적 연구

이지운,김도훈,김성배,이창남,김상섭,김규석 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)

Composite action can be achieved by providing shear connectors between steel top flange and concrete topping. Composite sections have larger stiffness than the summation of the individual stiffness of slab and beam, therefore, can carry larger load or similar loads with appreciably smaller deflection and are less prone to transient vibration. T-type Steel Composite beam(TSC-beam) is developed and tested. To make the part of steel beam, we used the way of welding two steel plates as well as the way of folding one steel plate.

중심교합위와 중심위간의 변위가 하악운동에 미치는 영향에 관한 비교연구

이지훈,김광남,장익태 대한두개하악장애학회 1991 대한두개하악장애학회지 Vol.3 No.1

ABSTRACT The discrepancy between centric relation and centric occlusion have a great role on the successful prosthodontic and occlusal treatment. This study was performed to investigate the effect of the discrepancy between centric relation and centric occlusion on condylar guidance inclination and Bennett shift (immediate and progres- sive side shift). Sixteen adults who have physiologically normal occlusion and are free of TMJ dysfunction were selected. The amount of the sagittal CR-CO discrepancy in lower anterior incisor was ob- tained by Saphon Visi-Trainer. The amount of the CR-CO discrepancy in condylar level was measure.d on the individualized corrected tomography. Pantronic survey was performed by using a arbitrary hinge axis according to manufacturer's direction. All subjects were divided into two groups, group I (small) and group II (large), according to the amount of CR-CO discrepancy. At first the amount of the CR-CO discrepancy in condylar level between two gro was compared and then the condylar guidance inclination and Bennett shift be" "si-i two grou -^ were compared and analyzed. The results were as follows; 1. The average CR-CO discrepancy in lower anterior incisors was 0./'in;r: ? . i., 0.49mm anteroposteriorly, and 0.88mm in total. The average CR-CO di lar level was 0.43mm. 2. The CR-CO discrepancy measured on teeth level and condylar level were highly correlate d (p<0.01). 3. The correlation of the condylar position in the glenoid fossa between two groups was not statistically significant. 4. The large CR-CO discrepancy group showed greater amount of Bennett shift ?-nd >,, guidance inclination, but there is no statistical significancy. 5. It seems that the CR-CO discrepancy have greater effect on progressive side shift than ol""r elements of mandibular movements. Keywords: centric occlusion, centric relation, immediate side stuti. '"ressiv orbiting condylar inclination, protrusive condylar inclmatio:i.

골수염으로 발현된 재발성 콕시디오이데스 진균증 1예

백지현,박은영,정윤숙,홍재원,채윤태,진성준,최희경,신소연,한상훈,진범식,김창오,최준용,송영구,조남훈,김준명 대한감염학회 2009 감염과 화학요법 Vol.41 No.4

Coccidioidomycosis is a fungal infection that results from inhaling the airborne arthroconidia of the Coccidioides species. It is an endemic disease in the southwest part of North America and rarely diagnosed in Korea. As tourism to endemic areas and the number of immunocompromised patients have been increasing, the incidence of this infection has increased in non-endemic areas. Treatment is usually successful with antifungal agents; however, recurrence is common. It is difficult to decide when to discontinue the antifungal treatment especially in non-endemic areas where doctors are not familiar with the disease. We report a case of recurrent coccidioidomycosis manifesting as osteomyelitis after the treatment of the patient for disseminated coccidioidal infection. The complement fixation test was a useful tool for the assessment of patient response and to evaluate suspected recurrence.

섬유보강에 의한 고강도콘크리트의 내화성능 개선

오상균,김세훈,남지현 동의대학교 산업기술개발연구소 2005 産業技術硏究誌 Vol.19 No.-

Nowadays, it is a requirement to use high strength concrete for skyscrapers. Therefore safety research for high strength concrete is necessary. A fire outbreak in a reinforcement concrete structure looses the organism by the different contraction and expansion of hardened cement pastes and aggregate, and causes crack by thermal stress, leading to the deterioration of the durability. In this study, normal and high strength mortar were exposed to a high temperature environment. And than fundamental data for the character change of concrete heated highly were resented by measuring compressive strength of concrete with PP fiber and vinylon fiber, before and after heating. As the result, it is proven that adding PP fiber and vinylon fiber in high strength concrete for prevents deterioration of durability by fire.

CC Chemokine CKβ8의 발현 조절 물질 탐색 및 저해활성 물질 분석

김탁용,이태훈,백남인,정대균,김지영 경희대학교식량자원개발연구소 2005 硏究論文集 Vol.24 No.-

CKβ8은 CC 케모카인의 부류에 속하는 사이토카인의 일종으로, 단핵구, 호염구, 호산구, T 림프구, 자연살해세포, 수지상세포 등의 화학주성물질로 작용하는 것으로 알려져 있다. CKβ8은 염증반응 및 혈관신생 등과 같은 여러 가지 생체 반응에 역할을 하는 것으로 알려져 있다. 본 논문에서는 사람 CKβ8 유전자의 전사저해 물질을 선별하기 위하여 CKβ8/Luc 유전자를 발현하는 세포주를 확립하였다. CKβ8 유전자의 전사시작점에서 -299 부터 +10 프로모터 부위를 PCR에 의해 얻은 다음 포유세포 발현 플라스미드에 클로닝하였다. CKβ8/Lvc 유전자는 U937 세포내에서 PMA에 의해 10배 이상 발현이 증가한다. CKβ8/Luc 발현 U937 세포주는 식물 추출물에서 전사 저해제를 탐색하는데 이용되었다. 46 개의 식물 추출물 중에서 6개가 90% 이상 CKβ8/Luc의 전사를 저해하였다. 이들 물질에 대해 세포 독성 실험을 수행한 결과 그 중 한 개만이 세포 독성이 거의 없는 것으로 나타났다. 이 추출물은 붉나무에서 얻은 추출물이며 이 식물 추출물은 염증관련 질환에 대한 가능성이 있는 치료제로 이용될 수도 있을 것으로 추측된다. Ckβ8 belongs to a family of CC chemokines, which is known to act as a chemoattractant for monocytes, basophils, eosinophils, T lymphocytes, NK cells, and dendritic cells. CKβ8 is known to play roles in various biological processes such as inflammation and angiogenesis. In the present study, we developed U937 cell line expressing CKβ8/Luciferase fusion gene for screening of transcriptional inhibitors for human CKβ8 gene. Genomic sequences that contain CKβ8 promoter region from 299 to+10 nucleotide from the transcription start site was amplified by PCR and cloned into mammalian episomal plasmid. The CKβ8/Luc fusion plasmid was introduced into human promonocytic U937 cells and selected for stable U937 cells expressing the fused reporter gene. The expression of the fusion gene was induced by more than 10 folds upon treatment of phorbol myristate acetate. The stable U937 transfectant cells were used for searching transcriptional inhibitors for human CKβ8 gene from plant extracts. Among 46 plant extracts tested, six extracts exerted more than 90% inhibition of PMA-induced CKβ8 transcription. Cytotoxic tests demonstrated that one of extracts, which was extracted from Rhus chinensis Mill, had little cytotoxic effect. The extract may be used for developing a potential therapeutic agent for inflammatory diseases.

탄소섬유/고인성 에폭시 수지 적층판의 모드Ⅱ 파괴인성 평가

심재기,양인영,김영남,조규재,김지훈 朝鮮大學校 機械技術硏究所 1999 機械技術硏究 Vol.2 No.1

본 연구에서는 탄소섬유/고인성 EPOXY의 일방향 CFRP적층시험편에 대해 정적 ENF 시험 및 스프릿홉킨손봉법에 의한 동적 ENF시험을 하여 일방향 CFRP 적층판의 모드Ⅱ층간파괴인성치를 측정된 하중응답, 반력봉 반력의 J-적분과 시험편의 변위해석을 통하여 평가하였다 실험결과, 준정적 변위속도 δ = 5 × 10 근방에서 하중 최저점에서부터 하중의 진동이 발생하기 시작함을 알 수 있었으며, 또한 최저 측정점에서 하중점 변위속도의 증가와 더불어 동적 층간파괴 인성치가 증가함을 알 수 있었다. In this paper, an investigation was performed on the dynamic interlaminar fracture toughness of CFRP(carbon fiber reinforced plastics) composite laminates. Composite laminates used in this experimentation are CF/high toughness Epoxy Resin composite laminated plates. In the experiments, Split Hopkinson's Bar(SHPE) test was applied to dynamic and notched flexure test. The mode Ⅱ fracture toughness of each unidirectional CFRP was estimated by the analyzed deflection of the specimen and J-integral with the measured impulsive load and reactions at the supported points. As an experimental results, Loading vibrations are generated when quasi-static displacement velocity, δ becomes 5×10 from the lowest loading point. It is thought that the dynamic fracture toughness of specimens(CF/EPOXY) with the increase of displacement velocity becomes a little greater at a measuring point within the range of measurement.

색상 측정 기기를 이용한 복합레진 적층 수복과 단일 수복의 색상 비교 분석

송영상,김자현,이빈나,장지현,장훈상,황윤찬,오원만,황인남 大韓齒科保存學會 2012 Restorative Dentistry & Endodontics Vol.37 No.2

Objectives: This study analyzed the difference in color caused by different thickness in enamel layer of composite resins when applied with single and layering placement technique, and evaluated if the results agreed with the shade guide from the manufacturers to verify reliability of the color matching process of the manufacturers. Materials and Methods: For single composite resin samples, 6 mm diameter and 4 mm thickness cylindrical samples were fabricated using Ceram-X mono (DENTSPLY DeTrey) and CIE L*a*b* values were measured with spectrophotometer. Same process was done for layering compositie resin samples, making 3 dentinal shade samples, 4 mm thickness, for each shade using Ceram-X duo (DENTSPLY DeTrey) and enamel shade resins were layered in 2 mm thickness and CIE L*a*b* values were measured. These samples were ground to 0.2 mm thickness each time, and CIE L*a*b* values were measured to 1 mm thickness of enamel shade resin. Results: Color difference (△E*) between single and layering composite resin was 1.37 minimum and 10.53 maximum when layering thicknesses were between 1 mm and 2 mm and 6 out of 10 same shade groups suggested by manufacturer showed remarkable color difference at anythickness (△E* > 3.3). Conclusion: When using Ceram-X mono and duo for composite resin restoration, following the manufacturer's instructions for chossing the shade is not appropriate, and more accurate information for Ceram-X duo is needed on the variation and expression of the shades depending on the thickness of the enamel. (Restor Dent Endod 2012;37(2):84-89)

GO-17 : Makorin Ring Finger Protein 1 (MKRN1) as an adjunct marker in liquid-based cervical cytology

( Ji Yun Lee ),( Hyeong Ju Kim ),( Jinkyoung Kong ),( Ji Hee Choi ),( Geum Seon Sohn ),( Hanbyoul Cho ),( Eun Ji Nam ),( Sang Wun Kim ),( Doo Byung Chay ),( Sunghoon Kim ),( Young Tae Kim ),( Jae Hoon 대한산부인과학회 2014 대한산부인과학회 학술대회 Vol.100 No.-

목적: The aim of the study was to test the ability of MKRN1 to detect cervical lesion in a screening setting and its use as a surrogate marker of HPV infection. 방법: We conducted PROspective specimen collection and retrospective Blinded Evaluation (PROBE) study. Liquid-based cytology samples were collected from 187 women. A cell block was prepared from residual cervical cytology specimen for immunocytochemistry of MKRN1 and P16 INK4a.Liquid-based cervical cytology, MKRN1, P16 INK4a, P21, P57, KI-67 immunostaining on cell block sections, HPV hybrid capture and real time Polymerase chain reaction (PCR) were performed and analyzed with pathologic results.Clinical performances [sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV)] were calculated for all women and subgroup analysis was performed for patients with ASCUS or LSIL. 결과: MKRN1 positivity increased with histologic severity, from 32.4% in CIN1, 60.0% in CIN2, 80.0% in CIN3 to 92.3% in invasive cancer. The sensitivity, specificity, PPV and NPV of MKRN1 to detect CIN2+ was 73.8%, 76.8% 75.6%, and 75.0%, respectively. However, liquid-based cytology showed poorer clinical performance than MKRN1 immunostaining (61.3%, 69.5%, 66.2% and 64.8%, respectively) and HPV testing had lower specificity than MKRN1 (67.7%). When combining two screening tests, MKRN1 + HPV showed the highest sensitivity, specificity, PPV and NPV (71.8%, 85.5%, 82.3%, 76.5%, respectively), while there were no significant differences between cytology + HPV (60.6%, 81.8%, 75.4%, 69.2%) and cytology + MKRN1 (58.8%, 84.1%, 78.3%, 67.7%) in all aspects. In cases of ASCUS/LSIL, MKRN1 + HPV (100%, 72.7%, 73.9%, 100%, respectively) showed the best clinical performances followed by MKRN1 + cervical cytology (100%, 50.0%, 60.7%, 100%, respectively). 결론: MKRN1 was more sensitive and specific than liquid-based cytology, and it was more specific than HPV test. Our study showed that MKRN1 + HPV has the highest sensitivity and specificity when combining two diagnostic tests. As part of screening procedure, MKRN1 could be used as a satisfactory biomarker for the primary screening of cervical cytology.

The Structure of BC3N Tubular Nanofiber Synthesized by Using PECVD

Ji Hoon Yang,박종윤,양철웅,Cheong Hwan Yang,Chulsu Jo,Jae-Il Lee,Ji-Beom Yoo,Jong-Min Kim,Kyuwook Ihm,Min Hyung Yum,Myeung Hoi Kwon,Nam-Kyu Park,Seung Youb Lee,Tai-Hee Kang,Yong Sook Shin,Yong-Wan Jin,장영록 한국물리학회 2007 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.51 No.I

Boron carbonitride (B$_x$C$_y$N$_z$) nanotubes were synthesized with a gas mixture of C$_2$H$_2$, NH$_3$, N$_2$ and B$_2$H$_6$ by using dc plasma-enhanced chemical vapor deposition. The compartmented B$_x$C$_y$N$_z$ nanofibers were vertically aligned on the substrate with a diameter of $\sim$70 nm and a length of $\sim$3 $\mu$m. The transmission electron microscope images showed the B$_x$C$_y$N$_z$ nanofibers to be nanotubes with a well-aligned wall structure. The images of an elemental mapping taken by using a transmission electron microscope equipped with an electron energy loss spectroscope showed that the carbon, nitrogen, and boron atoms in the compartmented B$_x$C$_y$N$_z$ tubular nanofiber were uniformly distributed. The atomic composition ratio of the B$_x$C$_y$N$_z$ tubular nanofibers was investigated by using X-ray photoelectron spectroscopy. The estimated ratio of each chemical component of the compartmented B$_x$C$_y$N$_z$ tubular nanofibers was $x$ = 0.37 (boron) : $y$ = 1.0 (carbon) : $z$ = 0.36 (nitrogen), which is very similar with that of BC$_3$N. Based on the experimental data, we suggest a chemical structure of the BC$_3$N nanotube that is consistent with the structure obtained from a theoretical calculation. Boron carbonitride (B$_x$C$_y$N$_z$) nanotubes were synthesized with a gas mixture of C$_2$H$_2$, NH$_3$, N$_2$ and B$_2$H$_6$ by using dc plasma-enhanced chemical vapor deposition. The compartmented B$_x$C$_y$N$_z$ nanofibers were vertically aligned on the substrate with a diameter of $\sim$70 nm and a length of $\sim$3 $\mu$m. The transmission electron microscope images showed the B$_x$C$_y$N$_z$ nanofibers to be nanotubes with a well-aligned wall structure. The images of an elemental mapping taken by using a transmission electron microscope equipped with an electron energy loss spectroscope showed that the carbon, nitrogen, and boron atoms in the compartmented B$_x$C$_y$N$_z$ tubular nanofiber were uniformly distributed. The atomic composition ratio of the B$_x$C$_y$N$_z$ tubular nanofibers was investigated by using X-ray photoelectron spectroscopy. The estimated ratio of each chemical component of the compartmented B$_x$C$_y$N$_z$ tubular nanofibers was $x$ = 0.37 (boron) : $y$ = 1.0 (carbon) : $z$ = 0.36 (nitrogen), which is very similar with that of BC$_3$N. Based on the experimental data, we suggest a chemical structure of the BC$_3$N nanotube that is consistent with the structure obtained from a theoretical calculation.

Characterization of Staphylococcal Cassette Chromosome mec (SCCmec) Complex Integrated in Methicillin Resistant Staphylococcus aureus (MRSA) Isolates in Korea.

Nam-hoon Kwon,Kun-taek Park,Jin-san Moon,Hwa-young Youn,Yyoun-hee Lee,Jun-man Kim,Ji-youn Lim,Woo-kyoung Jung,Soon-keun Hong,Ji-youn Koo,Jin Hur,Sook Shin,Yong-ho Park 대한수의학회 2003 대한수의학회 학술대회발표집 Vol.2003 No.-