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      • SCIESCOPUSKCI등재

        Comparison of changes in retentive force of three stud attachments for implant overdentures

        Su-Min Kim,Jae-Won Choi,Young-Chan Jeon,Chang-Mo Jeong,Mi-Jung Yun,So-Hyoun Lee,Jung-Bo Huh 대한치과보철학회 2015 The Journal of Advanced Prosthodontics Vol.7 No.4

        PURPOSE The aim of this study was to compare the changes in retentive force of stud attachments for implant overdentures by in vitro 2-year-wear simulation. MATERIALS AND METHODS Three commercially available attachment systems were investigated: Kerator blue, O-ring red, and EZ lock. Two implant fixtures were embedded in parallel in each custom base mounting. Five pairs of each attachment system were tested. A universal testing machine was used to measure the retentive force during 2500 insertion and removal cycles. Surface changes on the components were evaluated by scanning electron microscopy (SEM). A Kruskal-Wallis test, followed by Pairwise comparison, was used to compare the retentive force between the groups, and to determine groups that were significantly different (α<.05). RESULTS A comparison of the initial retentive force revealed the highest value for Kerator, followed by the O-ring and EZ lock attachments. However, no significant difference was detected between Kerator and O-ring (P>.05). After 2500 insertion and removal cycles, the highest retention loss was recorded for O-ring, and no significant difference between Kerator and EZ lock (P>.05). Also, Kerator showed the highest retentive force, followed by EZ lock and O-ring, after 2500 cycles (P<.05). Based on SEM analysis, the polymeric components in O-ring and Kerator were observed to exhibit surface wear and deformation. CONCLUSION After 2500 insertion and removal cycles, all attachments exhibited significant loss in retention. Mechanism of retention loss can only be partially explained by surface changes.

      • KCI등재
      • SCIESCOPUSKCI등재

        Comparison of changes in retentive force of three stud attachments for implant overdentures

        Kim, Su-Min,Choi, Jae-Won,Jeon, Young-Chan,Jeong, Chang-Mo,Yun, Mi-Jung,Lee, So-Hyoun,Huh, Jung-Bo The Korean Academy of Prosthodonitics 2015 The Journal of Advanced Prosthodontics Vol.7 No.4

        PURPOSE. The aim of this study was to compare the changes in retentive force of stud attachments for implant overdentures by in vitro 2-year-wear simulation. MATERIALS AND METHODS. Three commercially available attachment systems were investigated: Kerator blue, O-ring red, and EZ lock. Two implant fixtures were embedded in parallel in each custom base mounting. Five pairs of each attachment system were tested. A universal testing machine was used to measure the retentive force during 2500 insertion and removal cycles. Surface changes on the components were evaluated by scanning electron microscopy (SEM). A Kruskal-Wallis test, followed by Pairwise comparison, was used to compare the retentive force between the groups, and to determine groups that were significantly different (${\alpha}$<.05). RESULTS. A comparison of the initial retentive force revealed the highest value for Kerator, followed by the O-ring and EZ lock attachments. However, no significant difference was detected between Kerator and O-ring (P>.05). After 2500 insertion and removal cycles, the highest retention loss was recorded for O-ring, and no significant difference between Kerator and EZ lock (P>.05). Also, Kerator showed the highest retentive force, followed by EZ lock and O-ring, after 2500 cycles (P<.05). Based on SEM analysis, the polymeric components in O-ring and Kerator were observed to exhibit surface wear and deformation. CONCLUSION. After 2500 insertion and removal cycles, all attachments exhibited significant loss in retention. Mechanism of retention loss can only be partially explained by surface changes.

      • 게껍질 Chitin 및 Chitosan의 소화관내 기능성에 관한 in vitro 연구

        장현주,전동원,이서래 이화여자대학교 생명과학연구소 1994 생명과학연구논문집 Vol.5 No.-

        반응 조건을 달리하여 게껍질에서 chitin을 추출하고 이를 탈아세틸화하여 chitosan을 제조하였으며, 이들의 물리, 화학적 특성과 소호관내 기능성을 in vitro법으로 실시하였다. 이들 chitin질의 bulk density는 127~208㎎/㎖, 정도는 0.1% chitin의 경우 80~581 cP, 0.5% chitosan은 80~3,670 cP로 다양한 수치를 나타냈으며, chitosan의 탈아세틸화도는 81~93%로 비교적 높았다. Chitosan 제조시의 알칼리 농도와 반응 온도가 일정할 때 반응 시간이 경과할수록 탈아세틸화도는 증가하였고, 점도는 감소하는 경향을 보였다. Chitin질의 보수력은 온도 상승에 따라 약간 상승하였고, 37℃ 에서 chitosan D가 가장 높았으며, bulk density가 낮을수록 높은 보수력을 나타냈다. Glucose 흡수 억제 효과는 bulk density가 낮고 보수력이 큰 chitin질이 더 컸고 chitosan D가 가장 높은 38%를 나타냈다. Chitin질의 bile acid 흡수억제 효과는 투석 1시간 후에 15~34%를 나타냈고, pectin은 39%, cellulose는 9%를 나타냈으며 chitosan D는 3% 농도에서 34%의 가장 높은 억제 효과를 나타냈다. Chitin and chitosan samples prepard from crab's shells under different conditions were compared for their physicochemical properties and functionality in gastrointestinal tract by in vitro test. Their bulk density was in the range of 127~208 ㎎/㎖, and their viscosity was 80~581 cP in 0.1% chitin and 80~3,670 cP in 0.5% chitosan solution, showing a wide variation. The degree of deacetylation in chitosan samples as determined by IR spectral analysis was relatively high, showing 81~93%. At the same alkali concentration and reaction temperature, a longer reaction period gave an increased degree of deacetylation and lower viscosity. The water holding capacity of chitic substance became greater at higher soaking temperature; chitosan D at 37℃ showed the greatest value. Chitic substance with lower bulk density showed the higher water holding capacity. The retardation effect toward glucose absorption was higher in chitic substances of lower density and higher water holding capacity; chitosan D showed the highest value of 38%. The retardation index toward bile acid absorption after 1 hour dialysis was 15~34% in chitic substances, 39% in pectin and 9% in cellulose. The retarding effect showed the highest value of 34% in chitosan D at 3% concentration.

      • SCOPUSSCIEKCI등재

        고혈압성 뇌출혈 환자의 뇌실질내 혈종의 화학적 성분 분석 : Preliminary Report

        전병찬,김창수,이규호,천태상,이화동 대한신경외과학회 1987 Journal of Korean neurosurgical society Vol.16 No.3

        The authors have analyzed various chemical components of intracerebial hematoma in 20 cerebrovascular accident patienis who were operated at the Department of Neurosurgery, Kosin Medical Center, from October, 1984 to April, 1986. The results show that there are no differences between the levels of sodium and chloride in serum and hematoma, while potassium and phosphorus significantly higher in hematoma, and calcium lower in hematoma. The changes of various chemical components seem not to be correlated with the timing of operation. We are going to discuss the possible explanations of the changes.

      • KCI등재

        A Case of Pneumatosis Cystoides Intestinalis in an Allogenic Stem Cell Transplant Recipient Who had Bronchiolitis Obliterans and Pulmonary Infection by Mtcobacterium abscessus

        김윤정,전은경,조병식,최수미,이석,민창기,신완식 대한감염학회 2008 감염과 화학요법 Vol.40 No.5

        Hematopoietic stem cell transplantation (HSCT) can cause various complications involving lung, liver intestine and other organs, Chemotherapy, radiation therapy, and graft-versus-host disease (GVHD) may injure the cells in the intestinal mucosa of HSCT recipients. Pneumatosis cystoides intestinalis (PI) is a condition that presence of air in the bowel wall is demonstrated by radiologic or pathologic tests, It is one of the infrequent complications after HSCT and is associated with several medical and surgical conditions. However its pathogenesis and definite etiologic factors are still unknown. Here, we present a case of PI in a HSCT recipient, who was diagnosed of bronchiolitis obliterance accompanied with chronic GVHD and pulmonary disease caused by Mycobacterium abscessus.

      • 사염화탄소의 간독성에 대한 파두 다당류분획의 예방효과

        이은경,길이룡,소동수,창동신,전선덕,정명규,문창규 한국환경독성학회 1996 환경독성보건학회지 Vol.11 No.2

        In present study, we fractionated polysaccharides from Croton tiglium and investigated their hepatoprotective effects on CCI₄ intoxication. Polysaccharide fraction of which molecular weight is over 300,000(HP) showed the most potent hepatoprotective effects on CC1₄ intoxication. Lipid peroxidation, BAST and sALT were used as parameters to evaluate the liver damage. Glucose, xylose and arabinose were found to be monosaccharides composing sugar moiety of HP.

      • 고콜레스테롤 혈증 환자에서 Cerivastatin(LIPOBAY, 의과학연구소)의 임상효과 및 안전성에 관한 연구

        박성훈,김미연,정수진,이영숙,박창한,변은경,전성희 梨花女子大學校 醫科大學 醫科學硏究所 2001 EMJ (Ewha medical journal) Vol.24 No.3

        목적 : Cerivastatin(LIPOBAY)은 최근에 개발되어 사용되기 시작한 HMG-CoA 환원효소 억제제로서 저용량으로 탁월한 콜레스테롤 강하효과를 보이는 약물이다. 저자들은 Cerivatatin(LIPOBAY)의 혈중 콜레스테롤 강하효과를 평가하고 약물의 안전성을 평가하기 위하여 본 연구를 시행하였다. 방법 : 고콜레스테롤혈증 환자 37명(남자 13명, 여자 24명)을 대상으로 하였다. 대상환자는 2주간의 저콜레스테롤 식이 후에도 혈청 콜레스테롤이 240㎎/㎗이상이거나, 관상동맥질환이 있는 환자는 혈청콜레스테롤이 220㎎/㎗이상인 경우 cerivastatin 0.4㎎을 8주간 복용하도록 하였다. 임상적 관찰과 검사실 검사(간기능검사, 일반혈액검사, 혈청지질검사)는 투약개시 후 4주 및 8주 후에 시행하였다. 결과 : Cerivastatin 0.4㎎을 4주간 투여한 후 측정한 LDL 콜레스테롤, 총콜레스테롤, triglyceride, 및 HDL 콜레스테롤은 각각 38%, 28.8%, 11.6% 및 7.8% 감소하였다. 총콜레스테롤/HDL 콜레스테롤 비 및 LDL/HDL비는 각각 20.8% 및 31.1% 감소하였다. 투약 8주후에 측정한 검사소견은 4주후에 비해 유의한 변화를 보이지 않았다. 한명의 환자(2.7%)에서 간기능 검사상 AST, 및 ALT의 지속적인 상승으로 투약을 중지하였다. 결론 : Cerivastatin 0.4㎎/day는 혈청콜레스테롤을 효과적으로 감소시켰으며 심각한 부작용은 볼 수 없었다. 따라서 적극적으로 LDL콜레스테롤을 낮출 필요가 있는 고콜레스테롤혈증 환자에서 cerivastatin은 효과적이고 안전한 약물이라고 생각된다. Objectives : Cerivastain(LIPOBAY) is recently developed HMG-CoA reductase inhibitor which is effective in lowering serum cholesterol levels at microgram does. We evaluated the clinical efficacy and safety of cerivastatin(LIPOBAY) in patients with hypercholesterolemia. Method : Thirty-seven patients(male : 13, female : 24) with hypercholesteolemia defined as baseline serum total cholesterol ≥240㎎/㎗, or ≥220㎎/㎗ in patients with known coronary artery disease were included for this study. After 2 weeks of low cholesterol diet, if the serum total choesterol level meet the criteria, cerivastain 0.4㎎/day was prescribed for 8 weeks. Clinical follow-up and laboratory tests were performed 4 weeks and 8 weeks after medication. Results : After 4 weeks of cerivastain 0.4㎎/day treatment, low density lipoprotein(LDL) cholesterol decreased 38% and total cholesterol decreased 28.8% from baseline. Triglyceride decreased 11.6%, and high density lipoprotein(HDL) cholesterol decreased 7.8% from baseline. Total cholesterol/HDL ratio decreased 20.8% and LDL/HDL ratio decreased 31.1% from baseline. After 8 weeks of treatment, no further significant changes were noted compared with the values at 4 weeks. Cervastatin was discontinued in one patient(2.7%) due to continuous liver enzyme elevation. Conclusion : Cerivastatin 0.4㎎/day is effective in lowering serum cholesterol levels without significant adverse reactions. Cerivastatin is effective and safe for patients with hypercholesterolemia who needs aggressive LDL cholesterol lowering.

      • KCI등재

        기술보고 : 굴포천 임시방수로 굴착구간 주변의 지하수 수위 변동 유형 분류

        김창훈 ( Chang Hoon Kim ),이수곤 ( Su Gon Lee ),한정상 ( Jeong Sang Hahn ),김남주 ( Nam Ju Kim ),전병추 ( Byeong Chu Jeon ) 대한지질공학회 2014 지질공학 Vol.24 No.4

        지하 대수층에 가해진 수문학적 충격에서 나타난 지하수위 변화를 관측하고 분석하여 굴포천 임시방수로구간의 지하수 수위변동 특성을 규명하였다. 지하수위란 그 지점을 지나가는 등포텐셜 값으로 지하수 압력이 그 위치에서 대기압과 균형을 이루고 있는 것으로, 이는 고정된 것이 아니라 수문학적 충격에 대응해서 변화하게 되는데 관측지점으로부터 지하수면까지의 깊이를 반복적으로 측정함으로서 파악할 수 있다. 김포-김포 국가지하수관측소의 1일 지하수 유출수문곡선의 지하수위 변화식과 변동폭을 평가요소로 하여 18개소의 관측시스템의 지하수 변동 특성을 영향형, 관측요망형, 비영향형 등으로 분류하였다. 그 결과 영향형은 전체의 50%로 수문학적 충격에 의해 수위변화가 민감하게 반영되며 임시방수로로부터 거리가우선적인 요인으로 판단된다. 관측요망형은 27.8%로 2개의 평가요소 중 1개가 기준에 미달한 경우이다. 비영향형은 22.2%로 지하수위 변화가 강우사상에 대해서만 반응함으로써 두 가지의 평가요소를 초과한 것들이다. Characteristics of water-level changes in the Temporary Gulpocheon Discharge Channel were identified by observing and analyzing changes in the subterranean water level induced by hydrological stresses the underground aquifer. The subterranean water level refers to the level at which the pressure of subterranean water passing through the corresponding position has an equipotential value that is in equilibrium with the atmospheric pressure at that location. This water level is not fixed but changes in response to hydrological stress. It can be identified by repeatedly measuring the distance from the observation point to the surface of the subterranean water. The subterranean water-level change equation and the variance range of the hydrological curve of subterranean water over 24 hours at the Gimpo-Gimpo National Groundwater Monitoring Network (NGMN) were used as assessment factors. The variance characteristics of the subterranean water at the 18 monitoring system locations were classified into three impact, observational wish, and non-impact. The impact type accounted for 50% of the subterranean water of and accurately reflected the water-level changes due to hydrological stress, showing that distance is the major controlling factor. The observational wish type accounted for 27.8% of the subterranean water, and one of the two assessment factors did not meet the assessment factors. The nonimpact type accounted for 22.2% of the subterranean water. This type satisfied the two assessment factors and represents subterranean water-level changes response to precipitation.

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