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Alloxan 유도 당뇨병상태에서 과산화지질생성에 미치는 Brazilin의 효과
안영수,길이룡,소동수,창동신,김진형,박광식,문창규 한국환경독성학회 1996 환경독성보건학회지 Vol.11 No.2
Brazilin was tested for its ability to inhibit alloxan induced lipidperoxidation. Lipid peroxide contents in liver, kidney and serum were measured by the TBA method. ICR mice receiving alloxan at a dose of 43mg/kg via the tail vein after a 24hrs starvation showed significantly increased lipid peroxide contents as compared to untreated control. Lipid peroxide contents in liver, kidney and serum of alloxan-induced diabetic mice were dose-dependently decreased by the treatment of brazilin at a dose of 10mg/kg, 50mg/kg, 100 mg/kg for 5 days.
이은경,길이룡,소동수,창동신,전선덕,정명규,문창규 한국환경독성학회 1996 환경독성보건학회지 Vol.11 No.2
In present study, we fractionated polysaccharides from Croton tiglium and investigated their hepatoprotective effects on CCI₄ intoxication. Polysaccharide fraction of which molecular weight is over 300,000(HP) showed the most potent hepatoprotective effects on CC1₄ intoxication. Lipid peroxidation, BAST and sALT were used as parameters to evaluate the liver damage. Glucose, xylose and arabinose were found to be monosaccharides composing sugar moiety of HP.
이은경,길이룡,소동수,창동신,전선덕,정명규,문창규 환경독성보건학회 1996 환경독성보건학회지 Vol.11 No.3
In present study, we fractionated polysaccharides from Croton tiglium and investigated their hepatoprotective effects on CCl$_4$ intoxication. Polysaccharide fraction of which molecular weight is over 300,000 (HP) showed the most potent hepatoprotective effects on CCl$_4$ intoxication. Lipid peroxidation, sAST and sALT were used as parameters to evaluate the liver damage. Glucose, xylose and arabinose were found to be monosaccharides composing sugar moiety of HP.
AIIoxan 유도 당뇨병상태에서 과산화지질생성에 미치는 Brazilin의 효과
안영수,길이룡,소동수,창동신,김진형,문창규,박광식 환경독성보건학회 1996 환경독성보건학회지 Vol.11 No.3
Brazilin was tested for its ability to inhibit alloxan induced lipidperoxidation. Lipid peroxide contents in liver, kidney and serum were measured by the TBA method. ICR mice receiving alloxan at a dose of 43mg/kg via the tail vein after a 24 hrs starvation showed significantly increased lipid peroxide contents as compared to untreated control. Lipid peroxide contents in liver, kidney and serum of alloxan-induced diabetic mice were dosedependently decreased by the treatment of brazilin at a dose of 10mg/kg, 50mg/kg, 100 mg/kg for 5 days.