심한 정신병적 증상을 나타낸 전신성 홍반성 루푸스 3례

문혜원,강민희,송정수,박원,김철응,이정섭,배재남 大韓神經精神醫學會 2001 신경정신의학 Vol.40 No.3

전신성 홍반성 루푸스(systemic lupus erythematosus, 이하 SLE)는 원인을 알 수 없는 자가항체 및 면역복합체로 인하여 여러 장기의 손상을 초래하는 질환이다. SLE의 신경정신의학적 증상에 대하여는 1872년 Kaposi에 의해 처음 기술되었다. 이때에 나타나는 임상적 양상은 상당히 다양하여 정신증, 우울증, 뇌졸증과 인지기능장애등을 포함한다. 이들은 종합적인 정신과적 평가를 위해 종종 협의진료가 의뢰되고 있다. SLE의 정신병적 증상은 환자의 사망률을 높이고 좋지 않은 예후를 시사하는 지표가 될 수 있기 때문에 조기 진단 및 치료가 요구된다. 그러나 SLE의 중추신경계 침범에 대한 명확한 진단기준이 마련되어있지 않고, 증상의 다양성과 변동성은 진단을 더욱 어렵게한다. 저자들이 경험한 심한 정신병적 증상을 보인 SLE 3례의 경우, 이들은 지남력 장애, 환시, 환청, 망상, 불안정한 기분을 보였고 자주 충동적이 되거나 난폭해져 자신 또는 타인에게 위험을 초래할 수 있었다. 현재까지 SLE의 정신병적 증상에 대하여 잘 알려져 있지는 않지만, 문헌고찰을 통해 발병기전, 분류진단, 임사양상, 치료등에 대하여 알아보았다. Systemic lupus erythematosus(SLE) is a disease of unknown etiology in which multiple organs are damaged by pathogenic autoantibodies and immune complexes. Neuropsychiatric manifestations in SLE were first described by Kaposi in 1872. These are so diverse that they include psychosis, depression, stroke, seizure and cognitive dysfunction etc.These patients are frequently consulted for psychiatric evaluation. Neuropsychiatric manifestations in SEL re also among the leading causes of morbidity and mortality and associated with poor long-term outcome. So it is essential to recognize and intervene these symptoms early. But the clear diagnostic criteria for CNS involvement in SLE have not been formulated, and diversity and fluctuation of illness make it difficult to confirm it. The authors reported three cases of SLE with severe neuropsychiatric manifestation. These patients showed symptoms such as disorientation, auditory and visual hallucibation, delusion and mood instability. They became frequently impulsive and violent and had risks to injure themselves or others. Although CNS involvement in SLE is not well known, we reviewed the pathogenesis, classification, diagnosis, clinical manifestation and treatment of them.

急峻펄스 電壓을 利用한 强力오존發生裝置開發에 관한 硏究

文在德,吳哲洙,鄭華淑 경북대학교 1985 論文集 Vol.40 No.-

The power efficiency of ozone generation can be substantially improved by modifying a direct discharge wire of a wire-to-cylinder type ozone generator to a helical strip line. and using a fast rising pulse voltage on it. It is raised 1.3 times up of ozone yield compared with that of 60 gO_3/KWh of the industrial silent discharge type ozone generator. Parametric studies also made to get the optimum design of ozone generator tested. The generated ozone concentration had a peak value with proper increasing the crest pulse voltage, the quantity of a pulse forming condenser capacity of the pulse generator, and the interelectrode spacing of self triggered stainless steel spark balls. It is found that the optimum strip line length of the ozone generator tested was about 2m in view point of energy consumption. And, input and terminal impedance also effected greatly to ozone generation, the generated ozone concentration were increased when the input impedance had been 25Ω while the terminal had been opened.

한국종합예술학교 무용원 예술사과정의 교과과정 특성 고찰

문성철,김재희 仁荷大學校 스포츠科學硏究所 2001 論文集 Vol.13 No.-

Study of the arts in the western world was established under two main structures; academic, theory-based institutions to educate & scholars, teachers and the performance-based conservatory for development of professional artists through apprenticeship. In contrast, arts education in Korea was established under one general structure, thus with neither specification nor specialization. With this reflections and the support of the government, The Korean National University of Arts(KNUA) has been established as a national art school with the purpose of advancing professional artists with both specialized academic and performance-driven programs through the most highly qualified faculty and advanced educational facilities available in the market. The purpose of this study was to analyze the problems of art bachelor's curriculum on school of dance in KNUA. The results of this study as follows: 1.An art bachelor's curriculum on school of dance lean upon kinesiological studies and technology models in the six models of curriculum theory for advancing professional artists with both specialized academic and performance - driven programs. 2.An art bachelor's curriculum on school of dance is insufficient for achieving the purpose of national art school, which is advancing professional artists with both specialized academic and performance-driven programs. 3.An art bachelor's curriculum on school of dance is insufficient for advancing professional artists with both specialized academic and performance-driven programs available in the market.

척수 동정맥 기형 : 증례보고 Case Report

최원철,강재규,도종웅,정현태,문성수 최신의학사 1991 最新醫學 Vol.34 No.12

위절제술 후 Carboxy-Methylcellulose를 이용한 위장관 조영술

오재천,김용수,문원진,임현철,고병희,조온구 한양대학교 의과대학 1997 한양의대 학술지 Vol.17 No.1

The purpose of this study was to determine the usefluness of the UGI study with Carboxy-Methylcellulose (CMC) and 140% barium in the patient undergone gastrectomy We reviewed the UGI study with effervescent agent and barium and the UGI study with CMC and 140% barium of twenty one patients, undergone gastrectomy (Billroth-Ⅱ:12, Billroth-Ⅰ:4 total gastrectomy:5). The average interval between these studies was 19 months. The coating quality of the remnant stomach, anastomosis sit e, jejunum and proximal ileum in two studies were compared. The maximum luminal diameter of the same site and the maximum distance between a adjacent valvulae conniventes were measured for evaluating the distensibility of these studies. Compared with the coating quality of the remnant stomach, the UGI study with effervescent agent and barium was superior to the UGI study with C MC and barium in 68% (11/16) patients. The difference of coating quality between these studies was marginal in the anastomosis site and jejunum. The UGI study with CMC and barium provided a better coating quality in the proximal ileum of 95%(20/21). The maximum luminal diameter of the anastomosis site, jejunum and proximal ileum was respectively 2.75cm, 3.36cm, and 2.82cm inthe UGI study with effervescent agent and barium, 3.2cm 3.35cm, and 3.40cm in the UGI study with CMC and barium(p〈0.01). The maximum distance between a adjacent valvulae conniventes of the jejunum and proximal ileum was respectively 0.61cm and 0.51cm in the UGI study with effervesent agent and barium, 0.74cm and 0.72cm in the UBI study with CMC and barium (p〈0.05). Compared with the distensibility, the UGI study with CMC and barium was superior. The UGI study with CMC and barium in subjects, undergone gastectomy, showed the advantage the mucosa distal to anastomosis site except for the remnant stomach and must be supply the more information in finding lesion such as adhesion and peritoneal dissemination.

백서 하악골의 기능적 전방위가 악관절 원판에 미치는 영향

배용철,경희문,장병천,성재현 대한치과교정학회 1994 대한치과교정학회지 Vol.24 No.4

This study was conducted to examine the changes in the shape of the Sprague-Dawley rats' articular disk following postural hyperpropulsion by observing their articular specimens through light and electronic microscopes after following 2-week and 4-week postural hyperpropulsion from their four weeks of age. The findings of this study are summarized as follow. It was shown that as compared with the control group, the experimental group indicated a significant increase in thickness of the 2-week groups' anterior and posterior portion of the articular disc. The experimental group showed statistically more significant increase in thickness of the 4-week groups' anterior portion of the articular disc than the control group. Light micrograph showed that the experimental group had more fibroblast in the anterior portion of the 2-week and 4-week groups than the comparing group. The 2-week groups showed in the findings through the electronic microscope that there were found the well developed and dilated RER which see-ms to actively synthesize the extracellular matrix including collagen, the cells with the well developed RER without distention which seems to actively synthesize the intracellular microfilaments due to the well developed free ribosome, and the typical chondroid cells. In addition, there was more fibroblast cell with the distended and well developed RER in the anterior area of the experimental group than that of the control group while fibroblast with the well developed RER and free ribosome was quite abundat. Based on the above result of this study, it was shown that the functional hyperpropulsion of the mandible causes the changes in the nature of the mechanical load to the certain portion of the articular disk. As a result, it seems that there may be occurred some changes in morphology of the disc by adaptation or confrontation with these changes at the cellular level.

食用油脂類에 對한 免疫生物學的 硏究

朴炳哲,文宰奎,朴榮吉,金杏順,安年衡,金度勳,金正勳,安榮根,李相根,鮮于演 圓光大學校 1990 論文集 Vol.24 No.2

食用油脂는 健康維持에 必須的인 營養素이다. 그러나 食用油脂는 脂肪을 構成하는 脂肪酸의 種類와 攝取하는 量에 따라 健康을 保衛하는 必須的인 食品의 成分이 되기도 하고 有害한 影響을 끼칠 수도 있어서 脂質代謝와 關連된 疾病 뿐만아니라 老化를 促進하고, 乳房癌, 大腸癌等의 癌發生과도 關連된 것으로 밝혀져 있다. 本 硏究는 우리生活環境에서 食用으로 接할 수 있는 10種의 油脂에 對한 免疫生物學的인 活性에서 究明한 結果 對照群인 참기름食餌群에 比해 올리브유食用群은 全般的으로 體液性 및 細胞性免疫을 有意性있게 增加시켰으나, 大食細胞의 活性과 末梢循環白血球數는 有意性없는 減少를 보였고, 動物性 油脂인 牛脂食餌群과 植物性 油脂인 옥수수기름食餌群, 들기름食餌群, 米糠油食餌群, 大豆油食餌群, 菜種油食餌群 및 고추씨기름食餌群에서는 全般的으로 體液性 및 細胞性免疫, 大食細胞의 活性 및 末梢循環白血球數를 有意性있게 減少시켰다. This study was performed to investigate the effects of edible oils and fats on the immunobiological responses in ICR male mice. Ten groups of experimental diets, such as sesame oil diet, beef tallow diet, lard oil diet, olive oil diet, corn oil diet, perilla oil diet, rice polishing oil diet, soybeen oil diet, rape seed oil diet, and red pepper seed oil diet were fed adlibitum to the ICR male mice for 27 days. The results of this study were summarized as followings. 1. Both humoral and cellular immune responses, phagocyte activity, and number of leukocytes in sesame oil group were increased. However, the increasing rate of body weight and the weight retios of spleen and thymus to body were generally decreased. 2. Hemagglutination titer(HA) and rosette forming cell(RFC) of the beef tallow group and the lard group were significantly lower than the sesame oil group(P<0.01), but the lard group significantly increased Arthus reaction and delayed type hypersensitivity(DTH)(P<0.01). 3. Arthus reaction, DTH, and RFC of the olive oil group were significantly higher than the sesame oil group(P<0.01). 4. DTH of the corn oil group was significantly higher than the sesame oil group(P<0.01) whereas phagochyte activity was significantly lower(P<0.01). But no statistically significant differences were found between the two groups in the humoral immune response. 5. HA, PFC, DTH, RFC, phagocyte activity, and number of leukocytes of the perilla oil group and the rice polishing oil group were significantly lower than the sesame oil group(P<0.01). 6. Both humoral and cellular immune responses, phagocyte activity, and number of leukocytes of the soybeen oil group, the rape seed oil group, and the red pepper oil group were significantly lower than the sesame oil group(P<0.01).

미소 가공면의 기움보정법에 관한 연구

양재용,윤문철 한국공작기계학회 2009 한국공작기계학회 춘계학술대회논문집 Vol.2009 No.-

The machined surface geometry of the workpiece after machining has been configured by using Confocal Laser Scanning Microscopy (CLSM) and the Wavelet-based filtering technique. The CLSM can be well suited to construct the three-dimensional machined surface of the workpiece. However, The raw heightness data of HEI(height encoded image) acquired by CLSM must be filtered due to the electronic and imaging noise occurring in constructing the surface image. So the Wavelet-based filtering algorithm is necessary to denoise the shape features in a micro scales so as to realize accurate topography analysis. The surface patterns filtered enable us to predict the machined surface shape in order to study the surface characteristics considering the tilting that is incurred in mounting. This study shows that the new technique by combining the CLSM and Wavelet-based filtering is an excellent one to generate the geometries of micro machined surfaces over a wide range of surface resolution in a micro scale.

지역사회획득 폐렴의 치료지침 권고안

송재훈,정기석,강문원,김도진,배현주,서지영,심태선,안중현,안철민,우준희,이남용,이동건,이미숙,이상무,이영선,이혁민,정두련,지역사회획득 폐렴 치료지침 제정위원회 대한감염학회 2009 감염과 화학요법 Vol.41 No.3

A successful therapy of community-acquired pneumonia requires appropriate empirical antimicrobial therapy. Etiology and antimicrobial susceptibility of major pathogens of pneumonia can differ by country. Therefore, an ideal treatment guideline of community-acquired pneumonia should be based on the studies performed in each country. We developed a treatment guideline for community-acquired pneumonia in immunocompetent adults in Korea. This guideline was developed by the joint committee of the Korean Society for Chemotherapy, the Korean Society of Infectious Diseases, and the Korean Academy of Tuberculosis and Respiratory diseases.

고속 Tube Expander의 동적 모델링 및 해석

김재량,정원지,김수태,최욱환 한국공작기계학회 2003 한국공작기계학회 추계학술대회논문집 Vol.2003 No.-

Tube expanding process is for combining a heat-sink plate with hair-pins (Cu-tube) through plastic deformation. The two parts, i, e., heat-sink plate and hair-pins are they components of a heat-exchanger for an air conditioner. This paper presents the analysis and dynamic modeling of a high-speed tube expander which integrates transfer of parts, fixing of parts, and tube expanding into one process. The 3-dimensional modeling of all the parts for the tube-expander was constructed using CATIA^(?). then the CATIA^(?) models are transferred into visualNastran^(?) to execute the 3-dimensional animation for checking prescribed cycle-time. The technique presented in this paper has been shown to be effective as a priori tool for verifying the design of a high-speed tube expander.