Comparison of 90‐day case‐fatality after ischemic stroke between two different stroke outcome registries using propensity score matching analysis

Yu, K‐,H.,Hong, K‐,S.,Lee, B‐,C.,Oh, M‐,S.,Cho, Y‐,J.,Koo, J‐,S.,Park, J‐,M.,Bae, H‐,J.,Han, M‐,K.,Ju, Y‐,S.,Kang, D‐,W.,Appelros, P. Blackwell Publishing Ltd 2011 Acta neurologica Scandinavica Vol.123 No.5

<P>Yu K‐H, Hong K‐S, Lee B‐C, Oh M‐S, Cho Y‐J, Koo J‐S, Park J‐M, Bae H‐J, Han M‐K, Ju Y‐S, Kang D‐W, Appelros P, Norrving B, Terent A. Comparison of 90‐day case‐fatality after ischemic stroke between two different stroke outcome registries using propensity score matching analysis. 
Acta Neurol Scand: 2011: 123: 325–331. 
© 2010 John Wiley & Sons A/S.</P><P><B>Background – </B> It has not been clarified whether the disparity in ischemic stroke outcome between populations is caused by ethnic and geographic differences or by variations in case mix. Propensity score matching (PSM) analysis can overcome some analytical problems but is rarely used in stroke outcome research. This study was to compare the ischemic stroke case‐fatality between two PSM cohorts of Sweden and Korea.</P><P><B>Methods – </B> Prognostic variables related to baseline characteristics and stroke care were included in our PSM model. Then, we selected 7675 Swedish and 1220 Korean patients with ischemic stroke from each stroke registers and performed one‐to‐one matching based on propensity scores of each patient.</P><P><B>Results – </B> After PSM, all measured variables were well balanced in 1163 matched subjects, and the 90‐day case‐fatality was identical 6.2% (HR 0.997, 95%CI 0.905–1.099) in Sweden and Korea.</P><P><B>Conclusions – </B> No difference is found in the 90‐day case‐fatality in propensity score‐matched Swedish and Korean patients with ischemic stroke.</P>

건국 우유와 유제품의 소비성향에 관한 조사연구

임종우,김종우,조광호,김영주,유제현,윤여창,장주익,권일경,안효일,이용규,이부응,박종래,이헌종 경상대학교 축산진흥연구소 1989 畜産振興硏究所報 Vol.16 No.1

라임병(Lyme disease : Borrelia burgdorferi) 매개진드기 (Ixodidae)에 대한 조사연구(Ⅲ)

심재철,윤영희,조양벽,이주연,신이현,양영철,박정은,이욱교,유효석,박경희 국립보건연구원 1994 국립보건원보 Vol.31 No.1

한국산 원유의 화학적 조성에 관한 연구 : 지역별 · 계절별

이현종,강국희,고준수,김영교,김영주,김종우,김현욱,박종래,유제현,윤여창,윤영호,임종우 제주대학교 농과대학 제주도축산문제연구소 1991 畜産論叢 Vol.6 No.1

Totally 881 bulked raw milk samples were collected once a month from Oct. 1989 to Sep. 1990 at 18 districts plus 8-16 farms in the all over Korea, and general composition of raw milk were analysed for the variation and correlation in between provincial areas, districts, and collection lines of milk plant. Each components of raw milk collected in province and district were significantly differed (p<0.001), but sampling stage were not effected on the composition of milk. In the monthly variation of milk composition, all of components excepted the content of ash in raw milk were lower in July and August, and tended to increas in October to January, and significantly (0.001) greater than in July and August. The correlation coefficients for the relation between fat content and total solids or protein were 0.635, 0.135 respectively, and between protein content and total solids or SNF were 0.652, 0.742.

Improving mechanical and magnetocaloric responses of amorphous melt-extracted Gd-based microwires via nanocrystallization

Belliveau, H.F.,Yu, Y.Y.,Luo, Y.,Qin, F.X.,Wang, H.,Shen, H.X.,Sun, J.F.,Yu, S.C.,Srikanth, H.,Phan, M.H. Elsevier 2017 JOURNAL OF ALLOYS AND COMPOUNDS Vol.692 No.-

<P><B>Abstract</B></P> <P>We report on the structural, mechanical, and magnetocaloric properties of annealed melt-extracted Gd<SUB>53</SUB>Al<SUB>24</SUB>Co<SUB>20</SUB>Zr<SUB>3</SUB> amorphous microwires of ∼70 μm diameter. During heat treatment small islands of nanocrystallities are generated and isolated in the amorphous region for the wires. The size of the nanocrystallities ranges from 5 nm to 10 nm. The observed lattice distortion from the nanocrystallities causes changes in the magnetic properties of the wires. The annealing temperature of 100 °C has the largest strength (1845 MPa) as compared to wires annealed at other temperatures. This is likely to trigger nanophase transformation in the amorphous region and these nanocrystals have been preserved through the increase of annealing temperature. The formulation of the nanocrystalline islands is also verified by the selected-area electron diffraction (SAED). The microwires exhibit a large and reversible magnetocaloric effect (MCE), with the maximum isothermal magnetic entropy change (−Δ<I>S</I> <SUB>M</SUB>) and refrigerant capacity (<I>RC</I>) values of 9.5 J/kg K and 689 J/kg respectively for the microwire annealed at 100 °C. This <I>RC</I> is about 35%, 67%, and 91% larger than those of bulk Gd<SUB>53</SUB>Al<SUB>24</SUB>Co<SUB>20</SUB>Zr<SUB>3</SUB> (∼509 J/kg), Gd (∼410 J/kg), and Gd<SUB>5</SUB>Si<SUB>2</SUB>Ge<SUB>1.9</SUB>Fe<SUB>0.1</SUB> (∼360 J/kg) regardless of their ordering temperatures. These results demonstrate the ability to tune the mechanical and magnetic properties of the microwires by thermal annealing.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The impact of nanocrystallization in Gd<SUB>53</SUB>Al<SUB>24</SUB>Co<SUB>20</SUB>Zr<SUB>3</SUB> microwires. </LI> <LI> Enhanced mechanical strength. </LI> <LI> Enhanced magnetocaloric response. </LI> </UL> </P>

간호대생과 비보건계열 여대생의 미세먼지 위험에 대한 인식과 지식, 건강 관리행위 비교 연구

김선미,김슬기,김진선,박주형,배다희,유수빈,유영주,임지향,최유진,Chen Mengyao,양숙자,손지희 이화여자대학교 간호과학대학 2019 이화간호학회지 Vol.- No.53

Purpose: This study aimed to know whether there is a comparison of perception, knowledge and health promoting behaviors about particular matter between nursing students and non-health departments college students. Methods: A quantitative research is used. Data were collected from August 1 to 19. The study sample was nursing students and non-health departments students. For the similar condition of samples, this study excluded whose first language is not Korean. Independent T-test and pearson’s correlation was used for this study. Results: A significant positive correlation did not existed between difference of major and perception(t=0.017, p=0.986), knwledge(t=0.652, p=.516) and health promoting behaviors(t=-0.114, p=.910) about particular matters. Conclusion: Based on the study results, there is no significant correlation of perception and actions about particular matters between nursing students and non-health department college students.

20대 여성의 데이트폭력 피해 경험과 우울, 불안 및 신체화의 관계

김수민,김예진,김유정,남지현,박금빈,박이준,안혜민,오세연,유가현,유다현,전예지,김옥수,길민지 이화여자대학교간호학회 2020 이화간호학회지 Vol.- No.54

Purpose: The purpose of this study is to examine the degree of date violence damage, depression, anxiety, and somatization among women in their 20s who had experienced date violence, and to investigate the correlations b etween the subjects’ experience of date violence damage and depression, anxiety and somatization. Method: The subject of this study were collected from September 04 to October 13, 2019, by posting advertisements on the women’s university community site in Seoul and a representative women;s community site on the Internet. 149 subjects were collected in their 20s who had experienced date violence from their partners. SPSS statistics 22.0 statistical program was used for data analysis, and standard deviation, T-test, ANOVA, and Pearson’s correlation coefficients were performed. Result: The results showed that the degree of experience of date violence was significantly correlated with symptoms of depression, anxiety, and somatization. Conclusion: Since there was correlations b etween depression, anxiety, and somatization symptoms in date violence victims, it is necessary to apply nursing intervention related to depression and anxiety to prevent somatization symptoms caused by date violence.

EHP와 RRV의 Coinfection에 의한 Reassortants 선발에 관한 연구

유제현,조홍찬,송진욱,김유성,이영건,박선오,이종익,김응률,차광종,류영수,Harry B. Greenberg 건국대학교 동물자원연구센터 1998 動物資源硏究誌 Vol.19 No.-

본 연구는 두 종류의 rotavirus strain MA104 cell 상에서 동시감염시킨 후 gene이 서로 교차된 새로운 reassortants를 선발하기 위해 수행하였으며, 수행한 결과는 다음과 같다. 1. EHP T 와 RRV를 MA104 세포에 감염시켜 cytopathic effect(CPE)를 확인하였으며 확인된 virus를 수확하였다. 2. Coinfection의 mobility of infection은 각각 EHP T는 0.3(3*10?? PFU), RRV는 2.5(2.5*10?? PFU)이었다. 3. EHP T와 RRV를 coinfection하여 plaque assay에 의해 형성된 plaque들을 pick up하였다. 4. EHP T와 RRV를 동시감염시켜 얻어진 plaques를 MA104 cell에 재감염한 후 grow up하여 수확하였다. 5. Plaques를 24 Well의 MA104 cell에 감염하여 수확한 후 dsRNA를 추출하여 전기영동에 의해 26개 reassortants를 선발하였다. This study was carried out to select new reassortants whose genes were exchanged by confection of two strains. The results obtained in these experiments were as follows: 1. Cytopathic effect was checked out in the experiment in which made MA104 cells infected by EHP T (murine rotavirus) and RRV(simian rhesus rotavirus). And then the viruses were obtained from the procedure. 2. Mobility of infection(MOI) of EHP T and RRV were 0.3(3*10?? plaque forming units) and 2.5(2.5*10?? plaque forming units)respectively. 3. After coinfection of EHP T and RRV, plaques which formed in plaque assay were picked up. 4. Coinfected EHP T and RRV plaques were grown up in 24 well of MA104 cell and then grown-ups or those were obtained. 5. By polyacrylamide gel electrophoresis(PAGE) of dsRNA extracted above, 26 reassortants were selected.

Predicting In Sacco Rumen Degradation Kinetics of Raw and Dry Roasted Faba Beans (Vicia faba) and Lupin Seeds (Lupinus albus) by Laboratory Techniques

Yu, P.,Egan, A.R.,Leury, B.J. Asian Australasian Association of Animal Productio 2000 Animal Bioscience Vol.13 No.10

Two laboratory techniques: (1) an in vitro method with two procedures for measuring protein degradabilities and (2) an in vitro method with three procedures for measuring protein solubility, were investigated to determine which laboratory techniques could most accurately predict the quantity of rumen protein degradation kinetics of legume seeds after dry roasting under various conditions, in terms of (1) rumen protein disappearance ($D_j$, where j=0, 2, 4, 8, 12, 24 and 48 h incubation), (2) rumen protein effective degradability (EDCP), (3) the parameters describing rumen degradation characteristics (the soluble fraction: S, the potentially degradable fraction: D, undegradable fraction: U, lag time: T0 and the degradation rate: Kd) and (4) rumen bypass protein (BCP), which were determined by the method accepted internationally at present, in sacco nylon bag technique using the standardized Dutch method. Feeds evaluated were the raw and dry roasted whole faba (Vicia faba) beans (WFB) and whole lupin (Lupinus albus) seeds (WLS), each was dry roasted under various conditions (at 110, 130 or $150^{\circ}C$ for 15, 30 or 45 min). In vitro protein degradability ($D_1$_Auf and $D_{24}$_Auf) were determined using the modified Aufr re method by enzymatic hydrolysis for 1 h and 24 h using a protease extracted from Streptomyces griseus in a borate-phosphate buffer. In vitro protein solubility ($bf_1$_S, $bf_2$_S, $bf_3$_S) was measured in a borate-phosphate buffer with three different procedures. Results from laboratory techniques (in vitro) were correlated and linearly regressed with in sacco results. Of the three procedures of in vitro protein solubility evaluated, none of them could predict in sacco results with good precision. The highest Pearson correlation coefficient ($R^2$) was less than 0.50. Of two procedures of in vitro protein degradability studied, the $D_1$_Auf values were closely correlated with in sacco parameters: Kd, EDCP and %BCP with high R' values: 0.82, 0.85 and 0.85, respectively, and closely correlated with in sacco $D_j$ at 2, 4, 8 and 12 h rumen incubation with high $R^2$ values: 0.83, 0.91, 0.93 and 0.83, respectively. The $D_{24}$_Auf values could not predict in sacco results. The highest $R^2$ value was less then 0.40. These results indicated that in vitro protein solubility measured in borate-phosphate failed to identify differences in the rate and extent of protein degradation of legume seeds after dry roasting under various conditions and thus should not be used to predict rumen degradation, particularly for heat processed feedstuffs. But in vitro protein degradability using the modified Aufr re method by enzymatic hydrolysis for 1 h or possibly an intermediate time (>1 h and <24 h) is a promising laboratory procedure to detect effectiveness of dry roasting legume seeds on rumen protein degradation characteristics and could be used as a simple laboratory method to predict the rate and extent of protein degradation in the rumen in sacco with high accuracy. The equations to predict EDCP, Kd and BCP of dry roasted legume seeds (WLS and WFB) under various conditions are as follow: For both: EDCP (%)=-1.37+1.06*$D_1$_Auf ($R^2=0.85$, p<0.01). For both: Kd (%/h)=-21.81+0.49*$D_1$_Auf ($R^2=0.82$, p<0.01). For both: %BCP=103.37-1.07*$D_1$_Auf ($R^2=0.85$, p<0.01).

치즈 제조 부산물을 이용한 ELISA Blocking Agent의 개발에 관한 연구

유제현,송진욱,조흥찬,차광종,박범석,김응률,이종익,이중복,谷口孝喜 건국대학교 동물자원연구센터 1999 動物資源硏究誌 Vol.20 No.-

본 연구는 유청과 탈지분유를 blotto로 이용하여 ELISA 수행시 항원·항체반응에 비특이반응을 막는 Blocking agent를 탐색하기 위해 실험을 수행했다. MAb의 역가측정 결과 유의차가 인정되는 OD값이 0.3이상 검색된 희석배율은 1B2의 경우 819,200배, 6D4의 경우 1,638,400배, 15B10의 경우 204,800배이었다. 서로 다른 Blotto가 항원·항체반응에 미치는 영향을 각기다른 MAb를 이용하여 조사해 본 결과 MAb Yo-156, Yo-5는 Blocking agent로 표준적으로 사용하고 있는 BAS가 비교하여 group A 바이러스 7종 모두에 비슷한 정도의 발색을 일으켰으며, MAb G6는 G6 type바이러스 4종 모두에서 비슷한 정도의 발색을 일으켰고, MAb G10은 G10 type 바이러스 3종 모두에서 비슷한 정도의 발색을 일으켰다. 따라서 본 실험에 사용한 모든 종류의 blotto소재인, 탈지분유1(서울우유(협)), 탈지분유2((주)매일유업), 혼합탈지분유((주)매일유업), whey powder1(Sigma), whey powder2 ((주)삼익유가공), WPC34((주)환이상사), WPC800((주)후드피아), WPC8000 ((주)후드피아), WPI((주)환이상사)는 현재 Blocking agent로 사용하고 있는 BSA와 비교하여 유사하게 비특이 반응을 막아주는 것으로 밝혀져 경제적으로 보다 저렴한 blotto 소재로 이용이 가능하다는 사실을 확인하였다. Enzyme-Linked-Immuno-Sorbent-Assay (ELISA) has been frequently used for detection of interaction of antigen and antibody. Many efforts have been made to reduce nonspecific reaction of ELISA. Bovine serum albumin (BSA) is usually used for blocking the nonspecific reaction even thought it is expensive. Recently skin milk has been focused on blocking nonspecific reaction of ELISA. This study aimed to substitute expensive blocking agent of ELISA with cheap by-product of cheese manufacture. To evaluate the substitution of BSA with wheys made in different companies, ELISA was carried out using monoclonal antibodies (MAbs) against rotavirus. The blocking capacity of the whey was compared with that of the BSA. The commercial wheys showed the same activity as BSA when ELISA was performed using MAb YO-156, S2-37, and Yo-5. To further investigate whether the whey affects the detection specificity of MAb, the ELISA was carried out using type specific MAbs. MAb G6 specific to serotype G6 bound to only rotavirus serotype G6 such as NCDV, UK, JBR, and Jedong strain whereas MAb G10 specific to serotype G10 bound to serotype G10 rotavirus only, demonstrating that the whey a and no effect on the binding specificity of MAb with respect to antigen-antibody reaction. These data indicate that the whey may have no effect on specific interation of antigen-antibody and may be widely used for blocking substitute because of competitive priority of its price.