균류 분화과정의 유전적 조절기작

박범찬,이환희,박윤희,박희문 충남대학교 생물공학연구소 2003 생물공학연구지 Vol.9 No.1

Fungi are well suited for studying mechanism controlling development and cell differentiation in multicellular eukaryotes. The asexual and sexual reproductive cycles are tightly coordinated during the life cycle of Aspergillus nidulans. The asexual (mitotic) reproductive cycle involves the formation of a number of differentiated cell types. Successful formation of multicellular reproductive structures and spores (conidia) requires the establishment of spatiotemporal gradients in essential transcriptional regulators, such as brlA, abaA and wetA. Altered gene expression is coordinated with critical changes in the movement of nuclei and the regulation of the cell division cycle. Therefore, it has been proposed to define a central regulatory pathway. Several early regulatory genes involved in signal transduction pathway controlling asexual sporulation are also required for activating the central pathway. Sexual (meiotic) reproduction is more complex, requiring the differentiation of several specialized tissue types. Although technical difficulties have limited efforts to study the genetics of sexual fruiting-body formation directly, some recent progress has been made. With the recent availability of mutants blocked in sexual development, understanding the genetic interactions between genes that function primarily in determining sexual sporulation will be achieved in the near future.

간호실무에서 신봉이론(Espoused theories)에 대한 탐색적 연구

서문자,김혜숙,이은희,박영숙,조경숙,강현숙,임난영,김주현,이소우,조복희,이명하,지성애,하양숙,손영희,권성복,김희진,추진아 성인간호학회 2001 성인간호학회지 Vol.13 No.1

As a nursing practice involves nurses' actions in a specific context of health care, this study has focused on exploring the espoused theories in nursing practice within the action science perspectives, Espoused theories are the belief, principles, and rationale expressed by the practitioner as guiding her/his actions in a situation of practice. The data were analysed qualitatively and 25 elements of espoused theories of nursing action were identified and clustered into 6 categories. The 25 elements of espoused theories are as follows: The clinical nurse worked in wholistic and individual nursing, focussed on the patient's needed, comfort and supportive nursing (5 theories of nursing goal) ; excellent skills, knowledge based, assessment and data collection, explaining, educating or a scientific basis(6 theories of nursing intervention): advocacy, value oriented, treatment, account- ability and commitment(4 theories of nursing ethics) ; human respect. partnership, trust(3 theories of patient-nurse relationship) : knowledgable, accumulated clinical experiences and personally lived experiences. positive perspectives(4 theories of nurse), role of intervention. rewarding peer relationship(3 theories of situations) The above mentioned espoused theories are similar to that of nursing textbooks which students learned through basic nursing education and almost the same as the Acts ofa Nurse in Korean. However, we are doubtful whether nurses actually do as they think. Therefore. it is recommended to review the theories-in-use in order to and any discrepancies between the espoused theories and the reality of nursing actions

바이모달 트램의 위치 인식 방법 및 정밀 정차 구현

서기원(Seo Ki-Won),박주연(Park Ju-Yeon),이상남(Lee Sang-Nam),류희문(Ryu Hee-Moon),변윤섭(Byun Yeun-Sub) 한국철도학회 2009 한국철도학회 학술발표대회논문집 Vol.2009 No.5월

This paper presents a method for precisely localizing and parking of bimodal trams. In order to gain an automatically driving system for bimodal trams, precise up-to-date localization, velocity recognition, distance to next station and precise parking location estimation functions are required. This paper proposes a system consisting of control device, steering device, sensor input equipment, driving system, tachometer, vehicle-side sensors, magnetic markers and magnetic sensors. The tram recognizes the precise location via magnetic markers containing information. Parking position and precise distance calculation is embodied by a tachometer. The vehicle-side sensors are used to assure safe station approaching and parking magnetic markers provide improvement of precision while tram parking. This paper provides a system realizing localization and precise parking and afterwards the automatic drive test results are reported and analyzed.

Increased expression of P53 and Bax in the spinal cords of rats with experimental autoimmune encephalomylitis

문창종,김승준,위명복,김희석,정종태,박전홍,지영흔,Tanumab, Naoyuki,Matsumoto, Yoh,신태균 濟州大學校 農科大學 動物科學硏究所 2000 動物科學論叢 Vol.15 No.1

The expression of pro-apoptotic molecules, p53 and Bax, in the spinal cord of rats with experimental autoimmune encephalomyelitis (EAE) was examined. Apoptosis was confirmed by the terminal deoxynucleotidyl transferasemediated dUTP nick end-labeling (TUNEL) method. TUSEL (+) apoptotic cells were mainly either ED1 (+) macrophages or T-cells in the parenchyma of E N . Western blot analysis showed that both p53 and Bax expression significantly ( p < 0.01) increased in the spinal cords of EAE rats at the peak stage, and thereafter declined. An immunohistochemical study showed that inflammatory cells (notably T cells) in the parenchyma express p53 and Bax, while brain cells, includng neurons and glia, were devoid of these nuclear staining of these molecules. The nuclear expression of p53 largely matches apoptotic cells in the parenchyma of EAE. These finchngs suggest that pro-apoptotic molecules, p53 and Bax, may play an important role in eliminating T cells in the parenchyma in EAE.

농업계열 특성화 고등학교 학생들의 교육 만족도 분석

박행모,문승태,김희수 한국농업교육학회 2008 농업교육과 인적자원개발 Vol.40 No.3

본 연구의 목적은 농업계열 특성화 고등학교에 재학 중인 학생틀의 교육과정, 수업, 학교시설, 교육 성과, 교사, 동료 학생관계에 대한 교육 만족도를 분석하는 데 있다. 전국의 농업계 특성화 고등학교 중 5개 농업계열 특성화 고등학교를 선정하여, 재학생 272명을 연구대상으로 하였다. 자료 분석은 빈도, 백분율,F 검증(일원변량분석), 사후검증을 실시하였다. 이 연구로부터 나타난 결과는 다음과 같다. 첫째, 교육과정에 대한 만족도에서는 현장 실습 프로그램을 제한적으로 운영하는 학교보다 다양한 현장 실습 프로그램과 특별활동을 운영하는 학교에 재학 중인 학생들의 만족도가 높게 나타났다. 둘째, 수업, 교육성과, 교사 영역에서는 기존의 과정만을 따르는 것이 아닌 자체적으로 교재를 만들고, 해외 연수 기회를 주어 사회 진출시 유용하게 사용될 수 있는 학교에 재학 중인 학생틀의 만족도가 높은 것으로 나타났다. 또한 특정학과로만 특성화 교육이 운영되는 것이 아닌 학교 전체적으로 특성화 교육이 이루어지는 학교에 재학 중인 학생틀의 만족도가 높은 것으로 나타났다. 그리고 교사가 책임감을 가지고, 학생들에 대한 관심 정도가 높을수록 학생들의 만족도가 높게 나타났다. 셋째, 교육시설 영역에서는 특정 학과로만 특성화 교육이 이루어져 시설적인 면이 충분하지 못한 학교보다 실외 실습장과 수업과 관련한 다양한 시설을 구비한 학교에 재학 중인 학생들의 만족도가 높게 나타났다. 넷째, 학생 동료와의 관계 영역에서는 다양한 동아리 활동이 개설되어 있는 학교에 재학 중인 학생들의 만족도가 높게 나타났다. The purpose of the current study is to analyze educational satisfaction of students in terms of curriculum, class, school facilities, educational outcome, teachers and students by agricultural specialized high school. The study was conducted with 272 students attending five agricultural specialized high schools in the nation. For analyzing data, frequency analysis, percentage, F test(One-way ANOVA) and post-test were implemented. The study results are as follows. First of all, in satisfaction for curriculum, students who attend the school operating various practice programs and extracurricular activities showed higher satisfaction than those who attend the school operating practice programs restrictively. Secondly, in class, educational outcome and teachers, students who attend the school making their own teaching materials, not just following the existing courses, and giving opportunities to go abroad that can be used in entering into society showed high satisfaction. Also, students who attend the school operating specialized education over the entire school, not operating it only in a specific department, showed high satisfaction. And, the higher teachers' sense of responsibility and concern about students are, the higher the student's satisfaction is. Thirdly, as for school facilities, students who attend the school having places for outdoor practices and various facilities related to lesson showed higher satisfaction than those who attend the school lacking in facilities because of the operation of specialized education only in a specific department. Fourthly, in relationship with peer students, students who attend the school establishing various group activities showed high satisfaction.

現代精神科疾患의 分類, 原因 및 精神病理에 對한 考察

朴汶熙 최신의학사 1978 最新醫學 Vol.21 No.8

보건관리 대행사업 평가 지표 및 척도개발에 관한 연구

박정일,조병희,구정완,김광종,김현욱,원종욱,이명숙,이원철,정문희 가톨릭대학교 산업의학센터 2000 韓國의 産業醫學 Vol.39 No.3

This study was carried out to develop the index and the scales for the evaluation of the group occupational health services(GOHS). The possible variables of each step, firstly, based on an evaluation model composed of four steps, input, throughout, output and outcome, were selected through several meetings of professional committee. And five types of questionnaire(for doctor, nurse, industrial hygienist, employer, and employee) were developed based on the selected variables. A pilot survey for four GOHS institutions and 12 enterprises was conducted using the questionnaires and correlation analysis for extracting variables was done. The results were as follows: 1.The evaluation scale was composed of three areas(evaluation on workers' health and work environment, evaluation by institution and employer, and evaluation by employee)which were devided into ten subscales. 2.Among firstly selected ninety-six variables, forty-three variables (11 for input, 14 for throughout, and 18 for output indices) were extracted by correlation analysis. 3.Based on the extracted variables, the questionnaires were simplified as five items for doctor, thirty-six items for nurse, nine items for industrial hygienist, and twenty-six items for employer and employee. 4.The total score of evaluation model was defined on the basis of four-hundred points as sum of four indices (input, throughout, output and outcome) given one-hundred points each.

종합병원 간호사의 밤번 근무에 영향을 미치는 요인에 관한 연구

박혜자,유인영,이영미,정문희 한국보건통계학회 2003 보건정보통계학회지 Vol.28 No.1

This study is conducted to find influencing factors on unrse's night shift works. From 20th July to 20th August, the survey was performed in a general hospital located at Kyunggi-do area, by the use of questionnaire. Collected 204 data were analysed through SPSS/Win 11.0. Results are as follows: 1. It was shown that night shifting word periods in special ward is longer than that in general ward. Exactly, shifting periods of night nurse work is 28.7days, 16.7days in special and general ward, individually. But numbers of night nurse worker are 3.4 and 2.48 persons in special and general ward, individually. And there were more patients in general wards than that in special ward. Namely, 54.3 patients in general ward and 19.3 patients in special ward. And off duty days and overtime on average in general ward were more much than that in special ward. The preference about night nurse works, the general ward was higher than that in general wards. In case of avoiding the night nurse work, the reasons that were mental stress. excess of duty, the burdens on work by oneself in general wards were shown much more frequency than that in special ward. 2. Physical-mental, social conditon of nurse worker's health in special wards were better than that in general wards. The stress level of nurse workers in general ward was higher than that in special ward. The factors of the influence on the preference on social-mental conditions of health were number of off duty days on average per month, number of night nurse working, and income of all family. Therefore, theses results were shown that the stress of nurses in general ward was much more than that in special ward. And the preference on night nurse work in general ward was lower than that in special ward. Accordingly, It was shown that the policy for support were need. The nurse administrator have to prepare complementary systems in organized level, to develop the positive recognition about night nurse work. For example have to reduce the dissatisfaction with systematic improvement, in other words control of off duty bonus, reasonable overtime and night nurse work bonus, and night working periods, and with control nursing human power and policy for reduction of overstres according working conditions and characters of business in various types of ward.

年齡에 따른 외국어 습득 戰略의 差異點에 관한 硏究

朴熙文 培材大學校 1984 論文集 Vol.5 No.-

The purpose of the study is twofold : (1) to neurolinguistically investigate the relationship between human biology and language acquisition , and (2) to diagnose the adequacy of beginning age d English learning in Korea on the basis of different learning strategies between children and adults . The research reveals that the 'early - age sensitivity hypothesis', insisting that between the ages of two and early teens the individual appears to be most sensitive to verbal stimuli and to preserve some innate flexibility which is definitely necessary for the smooth elaboration of speech and language, still dominate in related literatures in spite of its own theoretical vulnerabilities. The research also shows that 'lateralization' referring to the complementary specialization of brain function seems to occur around 12 years old, and the phenomenon appears to have a crucial effect on human language acquisition. After this period brain seems to lose its plasticity for language learning. As for the different learning strategies according to age differences, whereas in childhood syntax seems to enjoy maximum development, in adulthood acquisition of syntax seems to be no longer easy. Instead, adults seem to continue their language learning mainly depending on vocabulary expansion. Korean students begin their English learning from junior high school period (around 13, 14 yearn old) after spending the so-called 'critical period' for 1anguage acquisition. In this regard, the author cautiously proposes that for more effective English education the beginning age of English learning in Korea should be towered to around 10 years - old when lateralization is not completed yet.

척추 골다공증에서의 골절 위험 한계치

박진영,유문집,유석주,이성철,박희곤,김명호 대한골대사학회 1995 대한골대사학회지 Vol.2 No.2