생활치 미백제가 우치 법랑질의 투명도에 미치는 영향

김동준,김영주,김학근,박은종,서은주,황윤찬,오원만,황인남 大韓齒科保存學會 2005 Restorative Dentistry & Endodontics Vol.30 No.3

본 연구에서는 현재 임상에서 home bleaching을 위해 사용되고 있는 표백 재료들이 치아 법랑질의 투명도에 어떠한 변화를 일으키는지 고찰해 보고자 시행하였다. 실험 대상으로는 하루 전 발거한 우치 (bovine tooth)를 사용하였다. 치아의 순면에 수직되게 다이아몬드 드릴을 이용해 수주 하에서 직경 6 mm의 원통형 치아 시편을 만들어 순면이 노출된 상태로 투명한 아크릭 레진에 포매한 후, low speed diamond saw (Isomat, Buehler Co., USA)를 사용하여 1.2 mm 두께로 절단하였다. 절단된 시편은 순면을 먼저 편평하게 연마하고,절단된 면을 연마하여 두께 1 mm의 시편을 완성하였다. 완성된 시편(우치 25개)을 무작위로 추출하여 3개의 그룹으로 나누고 나머지는 대조군으로 하였다. Opalescence (10% carbamide peroxide, Ultradent, Milford, USA), Rembrandt (10% carbamide peroxide, DenMat, USA) 및 Opalescence F(15% carbamide peroxide with fluoride, Ultradent)를 시편의 순면에 1주일 동안 적용 (표백제는 24시간마다 교체)하였고, 설측면은 증류수를 적신 거즈에 접촉된 상태로 보관하였다 표백제를 적용하기 전과 적용 3, 5, 7일째에 시편의 삼자극치 X, Y, Z 값을 색채색차계 (Color & Color Differencemeter, Model TC-6FX, Tokyo Denshoku Co., Japan)로 백색 배경판과 흑색 배경판 상에서 측정하였다 백색 배경판과 흑색 배경판 상에서 측정된 Y값의 평균값을 이용해 contrast ratio를 계산하였다 얻어진 값을 One Way Repeated Measured ANOVA를 이용하여 통계 처리한 결과 10% Opalescence처치군, 15% Opalescence-F처치군 및 대조군에서는 통계적으로 유의할만한 증감을 보이지 않았고, Rembrandt처치군에서는 Contrast ratio가 증가하였다 (p < 0.01) . This study was done to evaluate whether vital bleaching agents could influence on the translucency of the bovine enamel. The anterior bovine teeth that were extracted one day before and without any gross discoloration were obtained and then were preserved in physiologic saline. 6 mm cylindrical tooth specimens were fabricated with diamond puncher perpendicularly on labial surface of bovine tooth. After embedded in transparent acrylic resin with labial surface being exposed, they were cut to a thickness of 1.2 mm with low speed diamond saw (Isomat, Buehler Co., Lake Bluff, IL, USA). They were smoothly ground to 1 mm thickness of enamel with sandpaper. 24 specimens were randomly divided into 3 groups and control group respectively. Opalescence (10% carbamide peroxide, Ultradent, South Jordan, USA), Rembrandt (10% carbamide peroxide, DenMat, USA) and Opalescence F (15% carbamide peroxide with fluoride, Ultradent, USA) were applied on labial sides of the bovine enamel for 7 days (bleaching agents were reapplied every 24 hours) and the opposite surface was contacted to cotton that soaked in distilled water. The control group was soaked in distilled water. Three stimulus value X, Y and Z were evaluated with colorimeter (Color ' Color Differencerneter, Model TC-6FX, Tokyo Denshoku Co., Japan) on the labial surface of all specimen three times on white and black background plate before the bleaching agents were applied and on 3rd, 5th and 7th day after applied. The degree of translucency was normally assessed by measuring the inverse property, opacity (contrast ratio). 10% Opalescence, 15% Opalescence-F, and control group showed no significant variation in the translucency of bovine enamel, However Rembrandt decreased the translucency of it (p < 0.01).

제 3형 Gaucher세병으로 인한 진행성 근간대성 간질 2예

허경,예종수,김상진,김성은,김응규,조효근,김찬환,김현주 대한신경과학회 1999 대한신경과학회지 Vol.17 No.3

자궁암세포(HeLa)에 대한 사군자탕과 수종 항암제의 병용투여 효과

은재순,김현욱,소준노,오찬호,이송재 又石大學校 1993 論文集 Vol.15 No.-

The studies were conducted to investigate the combined effects of Sa Kunja Tang(SKT) and several anti-cancer drugs. The effects of SKT and several anti-cancer drugs on the proliferation of HeLa cells, human cervical cell line, was estimated by MTT colorimetric assays. The SKT extract inhibited the proliferation of HeLa cell at 10^-4g/ml. The inhibitory action of the mitomycin C(MMC), mercaptopurine(MCP) and 5-fluorouracil(5-Fu) treated group, respectively, on the proliferation of HeLa cell was increased by the SKT. When the mice were treated by the MMC, the number of leukocyte was decreased significantly at the 1st and 3rd day, but recovered at the 7th day. In the groups of the MMC treated with the SKT, the number of leukocytes was increased significantly than the group of the MMC treated only at the 3rd day. The SKT extract decreased the thymus weight of mice. The SKT extract increased the number of plaque forming cells(PFC), but the MMC treated group decreased the number of PFC. The combined treatment of MMC and the SKT increased the number of PFC significantly than the MMC treated group. The SKT extract increased the proliferation of T cells, but the MMC treated group decreased the proliferation of T cells. The combined treatment of MMC and the SKT increased T cell proliferation significantly than the MMC treated group. In conclusion, the results presented in this paper suggest that the SKT extract can decrease the dose of anti-cancer drugs on HeLa cell, and recover the side dffects of the MMC, such as leukopenia and immunosuppresion, without any intercalating the anti-proliferative action of the MMC in vivo.

황토와 생석회의 혼합비율에 따른 축산폐수 처리에 관한 연구

김보국,신은섭,원찬희 全北大學校 附設 都市및環境硏究所 1999 都市 및 環境硏究 Vol.14 No.1

This study was conducted in order to investigate removal efficiency of turbidity, organic matter, nitrogen and phosphorus to reduce environmental pollution of treatment livestock wastewater with mixed proportion of loess and lime. The result of study, the removal of turbidity, COD_Cr and T-P increased along the dosage, and was to be fixed above the appropriate dosage. In the removal turbidity, the appropriate mixed proportion of loess and lime was Loess:Lime = 3:7, the appropriate dosage was 30g. In the removal COD_Cr, T-P and TKN was Loess:Lime = 3:7, 30g, Loess:Lime = 5:5, 20g, Loess:Lime = 5:5, 40g, respectively.

사군자탕이 항암제를 투여한 마우스의 면역세포에 미치는 영향

殷載淳,金大根,柳東和,權鎭,洪鍾星,蘇俊魯,全焄,吳贊鎬 우석대학교 의약품개발연구소 1997 藥學硏究誌 Vol.2 No.-

The purpose of this research was to investigate effects of Sa-Kunja-Tang(SKT) on immune cells of antitumor drugs administered mice. The apoptosis and T lymphocytes subpopulation were tested using a flow cytometry, and the proliferation was tested using a MTT assay. The administration of etoposide. vincristine or doxorubicin increased the apoptosis of T-lymphocytes, but the action of doxorubicin was decreased by the administration of SKT. The administration of etoposide or vincristine decreased helper T and cytotoxic T cells population of T lymphocytes, but the action of vincristine was recovered by the administration of SCT. The administration of etoposide, vincristine or doxorubicin decreased the proliferation of T-lymphocytes, but the action of doxorubicin was increased by the administration of SKT. These results suggest that SKT has a regulative function of T-lymphocytes in anti-tumor drugs administered mice.

백반증 병변에 국한되어 발생한 건선 1예

김윤전,강희영,이은소,김유찬 대한피부과학회 2006 대한피부과학회지 Vol.44 No.4

수종의 근관세척액과 Listerine의 항균성 비교 연구

김영훈,강민경,최은경,양소영,양인석,강인철,황윤찬,황인남,오원만 대한치과보존학회 2009 Restorative Dentistry & Endodontics Vol.34 No.6

본 연구는 여러 가지 근관세척액(NaOCl, CHX, EDTA)과 구강세정제로 사용되는 Listerine을 근관감염균주인 Porphyromonas gingivalis와 Enterococcus faecalis를 상대로 항균효과를 비교하고 Listerine이 근관세척액으로 사용가능한지를 확인하고자 시행하였다. 본 연구에서는 Porphyromonas gingivalis ATCC 3327과 Enterococcus faecalis ATCC 29212의 표준균주를 사용하였다. 실험을 위한 근관세척제로 0.1%, 0.2%, 1%, 2% Chlorhexidine(CHX)과 0.5%, 1%, 2.5%, 5.25% NaOCl, 0.5M EDTA(18.6% EDTA). 그리고 Listerine원액을 이용하였다. 항균효과의 비교는 액체배지상에서 균주의 혼탁도와 한천 확산법을 이용한 억제대 비교로 하였다. 모든 실험군은 대조군과 비교시 근관내 균주에 항균성을 나타냈다(p < 0.001). 모든 농도의 NaOCl, CHX, 그리고 EDTA는 실험균주에서 높은 항균성을 보였다. 모든 실험에서 Listerine은 다른 근관세척제에 비해 낮은 항균성을 보였다. 결론적으로, Listerine이 E. faecalis와 P. gingivalis에 대해 항균성을 보이나, 일반적으로 사용되는 근관세척 액에 비해서는 현저히 낮은 항균성을 나타냄으로 근관세척 액으로 사용은 적합하지 않음을 나타냈다. The purpose of this study is to compare the antibacterial effect of Listerine on two microorganisms (P. gingivalis and E. faecalis) with various root canal irrigants (NaOCl, CHX, EDTA) and to identify possibility of using Listerine as a root canal irrigant. Porphyromonas gingivalis ATCC 3327 and Enterococcus faecalis ATCC 29212 were used in this experiment. For the test irrigants, 0.5%, 1%, 2.5%, 5.25% NaOCl, 0.1%, 0.2%, 1%, 2% CHX, 0.5M EDTA (18.6% EDTA) and Listerine were prepared. Distiled water was used as control. Two methods-1) Comparison of turbidity in broth and 2) Agar diffusion test-were used to determine the extent of antibacterial effect of Listerine and to compare it with that of NaOCl, CHX, and EDTA. All solutions tested were effective against two bacterial strains compared with control (p < 0.001). Any concentration of NaOCl, CHX, and EDTA showed similarly high effectiveness against all bacterial strains. In all experiment, Listerine showed significantly low antibacterial effect compared with the other root canal irrigants (p < 0.05). In conclusion, the results reflect remarkably low antibacterial effect of Listerine as compared with root canal irrigants in general so it is not suitable for the root canal irrigant.

충북 지역 초등학교 과학교육의 실태 조사

김찬종,이선경,김수환,고은성 淸州敎育大學校 科學敎育硏究所 科學과 數學敎育論文集 Vol.23 No.-

A survey was carried out comprehensively to investigate the present status of science education in primary schools 496 teachers in 199 primary schools in Chungbuk area participate in the survey. They questionnaire used in this study included items regarding goals or objectives for science education, approaches for instruction, teaching-learning strategies, assessment for instruction, teaching-learning strategies, assessment for instruction, computer use in science classes students' activity and the status of experimental equipment or tools for science education. Items on science textbooks and the understanding of the 7th national curriculum were also included in it. The results based on the teachers' responses were summarized and provided in this paper and it showed practices of science education in Chungbuk area.

이비인후과 영역의 급성 감염성 질환에 있어서 Tosugloxacin의 임상적 효과

김희남,김은서,이정권,이호기,김시찬 최신의학사 1996 最新醫學 Vol.39 No.1

발달장애유아의 언어행동발달 연구

김춘희,변찬석,서경희,유은정,이효신,전헌선,최성규 大邱大學校 特殊敎育·再活科學硏究所 2000 特殊敎育硏究 Vol.23 No.1

본 논문은 발달장애유아 언어행동발달 컨텐츠 개발에 요구되는 기초연구로써 연구의 이론적 바탕을 확립하고자 하였다. 연구에 사용된 방법은 문헌조사 방법 및 현장 인터뷰기법을 병행하였다. 본 연구의 주된 목적은 크게 3가지로 구분된다. 첫째, 발달장애유아의 가정 내 교육 욕구를 분석하고자 하였다. 둘째, 발달장애유아의 언어발달 양상을 검토하고자 하였다. 세 번째 목적은 유아의 언어행동발달 컨텐츠 구성의 주요 지침을 설정하고자 하였다. 이상의 연구목적에 따른 연구결과를 요약하면 다음 몇 가지로 제시된다. 1.가정 내 부모-유아간 관계형성이 우선 고려 되어야하고, 이에 따른 상호작용은 발달적 애착형성이 가능한 방향으로 정립되어야한다. 2.발달장애유아의 언어행동발달양상을 검토한 결과에 따르면, Piaget는 언어행동발달에 있어 감각운동기적 환경탐색 기능을 강조하고 있고, 이는 현재까지 중요한 유아 발달의 기저로 정착되었다. 따라서, 발달장애유아의 언어행동발달을 위한 컨텐츠 개발 내용에 있어서도 이러한 기저에 충실함이 합리적이다. 3.발달장애유아들에게는 언어행동 양상의 갈래가 크게 운동장애 및 감각결함으로 나누어질 수 있으므로, 이 두 가지 갈래의 각기 다른 특성이 컨텐츠 구성에서 충분히 고려되어야한다. 4.자폐성과 같은 중증 전반적 발달장애 유아를 위한 언어행동발달 컨텐츠 구성에서 특히 고려해야 할 두 가지 요소는 모방행동기능과 반복단순훈련기능 향상으로 결론지을 수 있다. This article planed to establish the theoretical foundations of the research as a basic study needed for developing the contents of verbal(language) behavior development for the infants with developmental disabilities. The methods used in the study was previous literature researches and interviews with subjects. The purposes of the study were divided into three parts. First, it was to analyze the educational needs of the infants with developmental disabilities in home settings. Second, it was to review and discover the language patterns of the infants with developmental disabilities. The third purpose was to devise the major guidelines of their language development's contents. The results of the study were described as the followings. 1.The relationships between the infants with developmental disabilities and their parents and their interactions should move to build the developmental attachments between them. 2.According to the literature findings of their language development patterns, Piaget concentrated on the functions of sensory motor environmental exploring in the language behavior development. The functions have been settled down into the important foundation for the infants' development. Thus, it was resonable that the content's development of the language behaviors for the infants with developmental disabilities should based on the function addressed by Piaget. 3.The language behaviors' patterns of the infants with developmental disabilities generally were classified into motor disabilities and sensory defect(deficiency). Therefore, the two factors should be considered for the constructions of the contents. 4.Constructing the contents of the language behavior developments for the infants with severely pervasive developmental disabilities such as autism, the improvements of two functions, imitative behavior and repetitive simple training should be considered.