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Yoonhyeong Byun,Eun Jin Kim,Areum Lee,Young-Ah Suh,Hee Ju Sohn,Jung Min Lee,Jae Seung Kang,Yoo Jin Choi,Youngmin Han,Hongbeom Kim,Wooil Kwon,Jin-Young Jang 대한외과학회 2022 Annals of Surgical Treatment and Research(ASRT) Vol.102 No.2
Purpose: Various hemostatic agents have been introduced in therapy as postoperative bleeding is a poor prognostic factor for postoperative outcomes. These products can be divided into those that directly promote the hemostatic cascade and those that physically form a barrier by absorbing blood. The latter, powder-type hemostatic agents have the advantages of being inexpensive and more absorbable with less foreign body reactions (FBRs) and are applicable to a relatively wide area. This study was conducted to verify the safety and efficacy of a newly invented polysaccharide product (OOZFIX, Theracion Biomedical), which improves blood absorption and hemostatic effects. Methods: Two separate animal experiments were performed. The first evaluated FBRs histologically at 3 days, 2 weeks, and 4 weeks, after implantation of OOZFIX in rats, and the second compared hemostatic performance of OOZFIX and Arista AH (Bard) in the porcine liver punch biopsy model. Results: We found minimal FBRs in the 3-day group and no reactions in both the 2-week and 4-week groups after implantation of hemostatic agents. The time to hemostasis of OOZFIX was not significantly different from that of Arista AH (median [interquartile range]: 9 [6–10] minutes vs. 8 [6–10] minutes, respectively; P = 0.522). When comparing the serial bleeding grade tendency, there was no statistical difference between OOZFIX and Arista AH (P = 0.656). Conclusion: OOZFIX caused a minimal FBR that disappeared within 2 weeks in vivo, and its hemostatic performance was comparable with that of an existing agent, Arista AH. Further clinical studies are required in the future.
유은아,김정수,민혜기 誠信女子大學校 1998 硏究論文集 Vol.36 No.-
성신여자대학교 교내 및 주변 음식점의 물이 음용수로써 적합한지의 여부를 검사하였다. 검수 속의 금속 및 중금속이온은 원자흡수분광법을, 무기 음이온은 이온쌍 크로마토그래피법을, 그리고 휘발성 유기물질은 Purge & Trap과 기체크로마토그래피법을 각각 이용하여 분석하였으며 물속에 들어 있는 대장균과 일반세균의 검출은 계절별로 실시하였다. 교내 검수 결과 대부분의 경우 금속 및 중금속 이온, 무기물 음이온, 휘발성 유기물질들은 환경부에서 제시한 기준치 이하로 검출되었으며 세균의 경우 일반 세균의 양은 기준치를 약간 넘는 양이었으나 대장균은 검출되지 않았다. 정수기를 통과한 물인 경우 일반 세균의 수가 감소한 것으로 보아 정수기의 필터만 잘 관리한다면 일반 세균까지도 제거할 수 있다는 장점을 나타내었다. 학교 주변의 경우도 대부분 기준치 이하로 존재하였으나 세균검사의 경우 여름철로 들어서서는 일반 세균의 검출수도 많아졌으며 특히 대장균이 검출된 경우도 있었다. Analysis of drnking water in and around Sungshin Women's University was carried out using Atomic absorption spectrometer for metal and heavy metal ion, Ion pair chromatography system for inorganic anions, and Purge & Trap and Gas chromatography system for volatile organic compounds. In addition we also measured the drinking water for bacteria and coli each season. Most chemical species in the school's drinking water tested below the maximum levels suggested by Korea's Ministry of Environment. Moreover, the number of bacterial colony is just above the suggested levels and there is no detection of coli. Around school the results were almost identical; however in the summer, some of the sampling water showed coli and an increase of bacterial colonies. The most significant result is there is much less or no detection of bacteria and coli in drinking water from clean sources than in water from unclean sources.
경막 내 colistimethate 투여로 치료한 다제 내성 cinetobacter baumannii 뇌실염
홍유아,유진홍,김진진,모은영,안건희,정희경,김진석,이현정,정미향,윤승배 대한감염학회 2009 감염과 화학요법 Vol.41 No.4
Acinetobacter species is a non-fermentative aerobic gram-negative coccobacillus that is an important pathogen found in nosocomial infections. Recently, multi-drug resistant Acinetobacter baumannii (MDR-AB) infections have been increasing and pose a serious problem. Most such infections present as bacteremia, pneumonia, or a wound infection; however, CNS infections are very rare. We herein present a case of ventriculitis caused by MDR-AB in a 37-year old man after a neurosurgical intervention. The patient was successfully treated with intrathecal colistimethate.
Separation Condition of Metalloporphyrins(Ⅰ)
Yoo, Eun-Ah 誠信女子大學校 1990 硏究論文集 Vol.30 No.1
Chromatographic behaviors of nickel and vanadyl metalloporphyrins were investigated by using two components solvent system on propanesulfonic acid functionalised silica as an adsorbent.