서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)

김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.

샘플링 검사를 통한 경제적 공정 목표 값 결정에 관한 연구

이동철,윤덕균 한국경영과학회 2000 韓國經營科學會誌 Vol.25 No.2

We consider the determinant of the most economical target value trough the sampling inspection by two consecutive machines. The machine sequence is fixed as products have to be processed by machine 1 first and then by machine 2 next. In this paper, we assume that if quality of a unit is lower than inspection lower specification limited, then the goods is not accepted. Otherwise, it is accepted. And we assume that the quality characteristic is larger-the-better characteristic and its distribution is the normal distribution whose standard deviation is known. This paper ends up with an numerical example by using the total expected profit function model that consider the scales profits. Inspection costs and material costs. And we analyze the variation of the total expected profit by changing coefficients of the functions.

Colchicine과 Verapamil이 PTH에 의한 골흡수에 미치는 영향

이종오,정동균 대한구강생물학회 1986 International Journal of Oral Biology Vol.10 No.2

This experiment was performed to study the effects of colchicine and verapamil on PTH-induced bone resorption in organ culture. Ulnae and radii were removed from 19-day fetal rats, prelabelled by subcutaneous injection of 200μCi ^45CaCl_2 into their mothers on the 17th day of gestation, and then explanted on the Millipore filters in organ culture dishes. The media of normal group were exchanged with fresh media, and control group with 0.1U/ml PTH-supplemented media, while experimental group, were exchanged with 0.1U/ml PTH+10^-7M colchicine, PTH+40μM verapamil, or PTH+10^-7M colchicine+40mM verapamil complexed media. Radioactivity of ^45Ca released into media after 24, 48 and 72 hours of culture and remained in cultured bone after 72hours, were both determined. The rates of bone resorption in each group were measured by the percentage of released ^45Ca to the total radioactivity that presented in the bone at the beginning of culture. And also effects of colchicine, verapamil and colchicine+verapamil were observed by the ratios of %-release of ^45Ca between paired control and experimental group. The following results were obtained: 1. PTH at the concentration of 0.1U/ml, increased the fetal bone resorption by 67 and 87% after 48 and 72hours of culture, respectively 2. Colchicine, at the concentration of 10^-7M, presented significant inhibition of PTH-induced bone resorption after 48 and 72 hours of culture, and verapamil, at the concentration of 40μM, presented significant inhibition of the PTH-tnduced bone resorption after 72 hours of culture. 3. Colchicine plus verapamil at the concentration of 10^-7M and 40μM, respectively, presented significant inhibition of PTH-induced bone resorption after 48 and 72hours of culture, but presented lack of additive or synergistic effects.

대전·충남지역 와병노인의 실태에 관한 연구

이동배,심운택,이태용,오장균,정성훈 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.1

This study was conducted to investigate the prevalence rate and the relationship between causative diseases and self-help abilities in bed ridden patients of the elderly. The study group was composed of 1.568 peoples aged 65 or more, living in Taejeon city and Chungnam provincial area. The results obtained were as follows : 1. The prevalence rate of bed ridden patients were 5.7% in male, and 4.3% in female. The rates revealed increasing basis with the ages. 2. The prevalence rate was higher in city area with 6.1% than inland and seaside area with 4.3%, 3.7% respectively. 3. The mean age of bed ridden patients were 75.9 years in male. 78. 0 years in female. The rates were variable with residential area. As the cause of bed ridden patients the cerebrovascular disease was higher in urban than rural area. 4. The mean age of causative diseases was the highest in contusion and fracture with 82.8 years. The period of bed ridding was the highest in muscular disease and arthropathy with 60.2 monthes. 5. The average score of activity of daily living was the highest in muscular disease and arthropathy and followed by respiratory disease, other disease, senility, cerebrovascular disease, contusion and fracture with decreasing basis. But most bed ridden patients did the activity of daily living similar to those of normal persons. 6. The causative diseases were diagnosed mainly in general hospital, hospital. and herb medicine. but muscular disease and senility were in self-diagnosed. 7. The helper of bed ridden patients were mainly wives or daughters in law.

흰쥐 Nucleus Raphe Magnus에 투여한 Morphine이 척수 Serotonin 유리에 미치는 영향에 관한 연구

이신재,임요한,최영님,김형룡,정동균 대한구강생물학회 1991 International Journal of Oral Biology Vol.15 No.1

It is known that the interaction between opioid neuron and serotonergic neuron in bulbospinal pathway has an important role on pain control. This experiment was perfomed to directly measure the release of serotonin into spinal cord superfusates before and after the microinjection of morphine and its antagonist, naloxone into the NRM of rats. High performance liquid chromatography with electrochemical detection was used to quantitate the amine. The injection of morphine into the NRM induced a significant increase in the amount of serotonin released in the spinal cord, which was reversed after the intraperitioneal injection of naloxone. These results support the proposal that : the analgesia produced by morphine microinjected into the NRM is mediated by the activation of spinally projecting serotonergic neuron.

한국인의 치아우식 조절에 관한 연구 : Ⅰ. 만경·동진강유역 음료수내의 수종 무기질 함량 Ⅰ. THE CONTENTS OF SEVERAL ELEMENTS IN DRINKING WATER AROUND THE REGIONS OF THE MANKYUNG AND DONGJIN RIVERS

이종흔,정동균,김중수,이효재,김각균,오귀옥,정태영 대한구강생물학회 1979 International Journal of Oral Biology Vol.3 No.1

Mineral analyses of water samples from several areas of the Mankyung River and the Dongjin River regions in Chonrabukdo where dental fluorosis was observed, which had been conducted between June in 1978 and January in 1979, have shown the following results. In general, the mean calcium concentrations were high in the areas where the mean concentrations of phosphorus and fluoride were low. And in the same area where dental fluorosis was particularly observed, seasonally a few minerals were variable─namely, calcium, phosphorus, and fluoride. Those samples of high fluoride concentration have higher phosphorus concentration, but calcium concentrations were the opposite phenomenon. Particularly, fluoride concentrations were remarkably greater during the cold season(January) than during the rainy season(July).

새로운 Fluorene계 발광 고분자 합성

李愚鵬,吳東元,朴美淑,黃悳海,宋智怜,朴在均 慶北大學校 科學敎育硏究所 2004 科學敎育硏究誌 Vol.28 No.-

Poly [2,7-(9,9-di-n-hexyl-fluorene-co-9,9-dibenzylidenylflourene)-2,7diyl] was synthesized through nikel-catalyzed coupling between 9,9-disubstituted 2,7-dibromofluorene and new fluorene-based monomer, 9,9-dibenzylidenylflurene in good yield. The polymer containing new fluorene monomer, 2,7-dibromo-9,9-dibenzylidenyflu -orene, which not only has extended π conjugation, but also has sterically hinderd sudstituents at the 9-position. The polymer obtained is found to be soluble in conventional organic solvents such as chloroform and was characterized by GPC, ^(1)H NMR and ^(13)C NMR. Also the UV absorption band showed the peak of maximum absorption at 373 nm and the photoluminescence (PL) spectra emission band showed the peak at 558 nm yellowish green region.

쇼트피닝 가공에 의한 자동차용 Drive Plate의 내구성 향상

이국진,이동선,이재헌,정성균 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

The effects of shot peening on the fatigue strength of SK-5M steel is investigated by experiment. The shot peening process is investigated optimum peening condition by changing impeller speed and exposure time. Bending fatigue test is accomplished to investigate the effect of optimum peening condition on the fatigue characteristics. As exposure time is increased, fatigue life in high stress is increased in early stage, become the maximum from 60 to 100 seconds, and then is decreased. Observing fracture surface through SEM after fatigue test, we can see clear configuration of cracks and peening layer.

FORMOCRESOL을 이용한 치수절단술시 FORMALDEHYDE의 전신적 흡수 및 급성독성에 관한 연구

이범모,한세현,김관식,정동균 대한구강생물학회 1990 International Journal of Oral Biology Vol.14 No.1

Formaldehyde that is active constituent in formocresol used in pulpotomy is known as toxic agent that causes systemic toxicity. To determine the fate of the ^14C-formaldehyde which was absorbed following its application to pulpotomy sites, by-pass of posterior facial vein and cannulation of external carotid artery were established with 20G-polyethylene tube. Blood samples (0.2ml) were collected in glass syringe before the pulpotomy and then at 0, 3, 5, 10, 20, 30, 45, 60, 90 and 120 minutes thereafter. Plasma was separated after centrifugation at 3000 x g for 15 min and aliquots of plasma were counted by liquid scintillation counter. After liver, kidney, lung ,heart, spleen, muscle, and alveolar socket were removed and solubilized with tissue solubilizer, the radioactivities in solutions were counted by liquid scintillation counter. The acute toxicity of formocresol was determined by BUN, GOT and OCT assay in blood samples collected 0, 2, 4, 6, 9 and 12 hours by means of cardiac puncture. The results were as follows ; 1. The radioactivity of ^14C-formaldehyde reached maximal value at 3-5 minutes and decreased thereafter. 2. About 8% of ^14C-formaldehyde placed in the pulpotomy site was actually absorbed systemically until 2 hours. 3. About 50% of ^14C-formaldehyde absorbed actually was distributed within 20 minutes. 4. The radioactivity of organ per gram was highest in the spleen and lowest in the muscle. 5. Total radioactivity of organ was highest in the liver and lowest in the heart. 6. There were no significant differences between control and experimental groups in BUN, GOT and OCT assay.

부갑상선 호르몬이 조골세포군의 교원분해효소 유리에 미치는 영향에 관한 연구

이인석,김관식,정동균 대한구강생물학회 1990 International Journal of Oral Biology Vol.14 No.1

Bone resorption is accomplished by the removal of both mineral and the organic matrix. The cellular origin of bone collagenase that is responsible for the removal of unmineralized organic matrix has remained equivocal. This study was performed to investigate the effect of PTH on the release of collagenase and cellular origin of bone collagenase in bone cell populations. Calvaria from fetal rat at 19-day of gestation, were sequentially digested by the enzyme solution consisted of collagenase, trypsin and EDTA for 10 min (PopulationI), 10 min (II), 10 min (III), 20 min (IV) and 20 min (V). Each bone cell population was primarily cultured for 6-7 days and splited to 5.0×10^5 cells/35mm culture dish and then incubated for 6 days with MEM with or without PTH (1.0U/ml). Collected medium was incubated with type I collagen for 6h at 37℃ and then used for hydroxyproline determination by Woessner's method. The results were as follows. 1. There were no significant differences of collagenase activity among 5 bone cell populations. 2. PTH (1.0U/ml) had no effect on the collagenase activity in the population I, II, III and V. 3. PTH (1.0U/ml) significantly increased collagenase activity in population IV.