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Pretreatment of Microfibrillated Cellulose on Polylactide Composites
이효재,유연성,김익수,김성훈 한국고분자학회 2020 Macromolecular Research Vol.28 No.2
Microfibrillated cellulose (MFC) in polymer has attracted increasing applications with the fully bioderived nanocomposites. Polymer composites from polylactide (PLA) and MFC were prepared using two different fiber preparations. Freezedried MFC was prepared and directly mixed with PLA in an internal mixer. The MFC premixed with PLA in an organic solvent was prepared, followed by an internal mixer for another composite. In addition, grafting cellulose on PLA using a compatibilizer was performed. In this research, composites containing 10 wt% MFC were used to investigate the influence of processing and compatibilizer on the mechanical and thermal properties. The processing procedure had a great influence on the mechanical and physical properties. The tensile strength was increased with filler loading and showed different values depending on the premixing step prior to processing. The storage modulus and loss tangent confirmed that the compatibilizer acted as the role of a bridge between filler and matrix, enhancing the mechanical properties. This experiment was conducted to compare the effect of pretreatment on the change of mechanical and thermal properties by using freeze-dried cellulose and cellulose suspension substituted with an organic solvent.
Cutaneous Scalp Metastases of Malignant Phyllodes Tumor of the Breast
이효재,임효순,기소연,이종은,이지신,박민호 한국유방암학회 2020 Journal of breast cancer Vol.23 No.3
Phyllodes tumor (PT) of the breast is a relatively rare fibroepithelial tumor that accounts for < 1% of primary breast neoplasms. PT is classified histologically as benign, borderline, or malignant, and a malignant PT has greater potential to metastasize than benign PT. Although almost all other organs can be affected, common metastatic sites are the lung and bone via the hematogenous route. There have been several studies reporting cutaneous and soft tissue metastases of PT, though the incidence is rare. Herein, we report a very rare case of scalp metastasis of malignant PT that was diagnosed via skin biopsy and surgical excision.
Malignant Apocrine Lesions of the Breast: Multimodality Imaging Findings and Biologic Features
이효재,강승완,이종은,정원기,이지신,박민호,임효순 한국유방암학회 2022 Journal of breast cancer Vol.25 No.6
The apocrine morphology of the breast is observed in a broad pathological spectrum, ranging from benign cysts to invasive carcinomas. However, the number of clinical research investigating malignant apocrine lesions is limited. This study retrospectively reviewed the data of patients with malignant apocrine lesions admitted in a tertiary center between January 2004 and December 2021, based on the radiology-pathology correlation and the recent advances in their status to enhance the therapeutic implications of androgen receptor (AR). Among the 37 patients with lesions, 27 (73.0%) had triple-negative subtypes with predominant AR expression. The radiological features of malignant apocrine lesions did not differ from those of typical invasive ductal carcinoma or ductal carcinoma in situ. This study demonstrated that knowledge on the imaging features of malignant apocrine lesions and their histological basis could enhance the adoption of new targeted therapies in patients with this particular type of breast cancer.
이효재,최화순,안면환,송정일 대한의용생체공학회 2002 의공학회지 Vol.23 No.1
본 연구의 목적은 척추 내고정 시스템인 척추경 나사못의 기계적 특성 평가를 통하여 내고정 시스템에 영향을 미치는 주요 하중요소를 규명하고. 하중요소에 대한 정하중 평가와 단분절 시스템(one bevel system)에서의 피로수명을 증가시키는 방법을 제안하는 것이다. 정하중 시험에서 단일 척추경 나사못(single pedicle strew)에 작용하는 하중요소는 마찰력((friction force), 굽힘력(bending force), 결합력(holding force)으로 나타났으며, 단일 나사못의 굽힘력 시험결과로부터 단분절 시스템에 대한 시험결과의 유추가 가능하였다 척추 내고정 시스템의 상부 부분 시험의 피로수명 보다는 봉(rod)의 유연성을 포함하는 단분절 시스템에서의 피로수명이 길게 나타났고. 인체에 삽입되는 척추경 나사못 단분절 시스템에서 근육 및 ligament 등에 의해서 봉의 유연성 저하를 가져올 수 있음을 고려할 때. 단일 나사못 피로시험만으로 단분절 시스템의 피로수명 예측이 가능함을 보였다. The purpose of this study was to investigate the important Parameters of the Pedicle screw by estimating the mechanical characteristics of screws under static and dynamic loads. Methodology for estimating Parameters under static load was proposed. It was also shown that the fatigue life of the one-level system could be increased by changing the shape of screws. Load parameters of the single pedicle screw were friction force. bending moment. and holding force. The test results of the one-level system could be inferred from teat results of the sin91e screw under bending force Fatigue life of the one-level system with flexible rod was longer than that of the upper Part test without rod . Considering the drop of flexibility of the rod due to muscles and ligament, fatigue life of the one-level system could be estimated b? that of the single screw.