혈액 투석 환자에서 중심정맥 협착에 대한 스텐트 삽입술 : Wallstent Placement

임대승,노상필,이유선,정승현,김보영,이정우,강정아,김정희,이민수,정준용,최시완,정진옥,성인환,이강욱,신영태 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.1

Stenosis of central vein is a common complication arising after percutaneous subclavian vein catheter insertion performed for temporary vascular access in chronic renal failure patients undergoing hemodialysis. There are several treatment methods for the condition like percutaneous angioplasty(PTA), stent insertion, and surgery, but recent trend is toward PTA and stents. Among the patients diagnosed with chronic renal failure from March 1993 to May 2002 and undergoing hemodialysis through AV fistula, the 14 Patients in whom central vein stenosis arose were selected for the study. A total of 28 percutaneous interventions(5 PTA and 23 stent placement) were performed, and restenosis rate and the time taken till the restenosis in de novo lesions and instant lesions were compared. All 28 cases were operated successfully. The 14 cases that received both anigioplasty and stent placement initially. (de novo lesion : 14 cases), Among the 10 cases with de novo lesion that followed up more than 1 year, 3 cases are currently undergoing hemodialysis without restenosis, and the remaining 7 cases have recurred stenosis with the mean time to restenosis of 10.9 months. In the 7 cases in whom stenosis recurred, 11 interventions were done(instent lesion: 11 cases). 4 of these were using only ballon angioplasty with 100% restenosis rate and the mean time of 3 months until restenosis. The remaining 7 cases were using both balloon angioplasty and stent placement, also with 100% restenosis rate but with the mean time of 12 months until restenosis, which was later than the group receiving only balloon angioplasty. In treating the patients with central vein stenosis, stent placement seems to be more advantageous over PTA in terms of restenosis rate and the mean duration of patency. In the case of instent lesion, inserting the stent for the second time after stenosis recurred lengthened the duration of patency compared to performing balloon angioplasty alone.

비만증 환자에서 한약제에 의한 체중 감소효과

Oh, Seung-Joon,Jeong, In-Kyung,Kim, Young-Seol,Choi, Young-Kil,Paeng, Jeong-Ryung,Bae, Jung-Hwan,Shin, Hyun-Dae 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Seung-Joon Oh, In-Kyung Jeong, Young-Seol Kim, Young-Kil Choi, Jeong-Ryung Paeng¹, Jung-Hwan Bae and Hyun-Dae Shin²Department of internal Medicine, College Medicine, Endocrine Research Institute¹. Department of Rehabilitation, College of Oriental Medicine², Seoul, korea. Bady Fat Reduction Effects of Red Ginseng Compound Preparation on the Patients with Obesity. Proceedings of International Symposium on East-West Medicine, Seoul. 244-254, 1999.-Obesity can be defined as a metabolic disease due to an increased state of fat tissues caused by an imbalance of calorie intake and use. Recently, in Korea by improvement and westernization of food intake, along with decrease in exercise activities, the prevalence of obesity has increased greatly. Our objectives were to study stability and effects of decrease in body fat by administering red ginseng compound preparation (known to have body fat decreasing effects in laboratory animals) to obesity patients on low calorie diets. Changes in weight and body fat were measured while carrying out calorie-restricted diets on patients for 4 weeks, then administering red ginseng compound preparation for another 4 weeks. The patients were 20 people whose BMI were 25kg/㎡ or over and whose percent body fat was also 30% or over when tested by bioelectrical conductivity. 1. Changes in weight were from 70.04kg(base line) to 67.43kg(after taking red ginseng compound preparation). 2. In similar sense, BMI decreased from 27.12kg/㎡(base line) to 26.56kg/㎡(after dieting), and further to 26.01kg/㎡ (after taking red ginseng compound preparation). The BMI seemed to decrease significantly compared to the baseline after the use of red ginseng compound. 3. Waist hip ratio was changed from 0.8858(base line) to 0.8728, but it was statistically insignificant. 4. The percent body fat was 35,16%(base line), 33.87%(after dieting), and 31.68%(after taking red ginseng compound preparation). 5. Complete blood cell count and blood chemisrty remained unaffected by the administration. 6. In concern to endocrinologic studies, T3 decreased from 118.7 to 98.2ng/dL, and T4 increased from 8.8 to 9.2㎕/ dL. Epinephrine showed a tendency to decreased from 0.27 to 0.25 ng/mL, and norepinephrine increased from 0.39 to 0.44ng/mL. 7. Leptin was not changed. 8. Some patients complained adverse effects; constipation(5 patients, may be due to diet therapy), fatigue (2 patients), pruritus(2 patients), flushing(s patients), dizziness(3 patients) and epigastric discomfort(2 patients). However their symptoms were mild, so medication did not stopped. In conclusion, loss of weight without significant side effects was observed during low calorie diet and red ginseng compound preparation administration. This is thought to be in relation to sympathetic nerve system rather than adrenal gland. Also, further long0term studies should be required, since the observed results were based on short-term changes in weight.

뇌졸중 환자에게 적용된 흡기근 훈련에 관한 국내 연구 동향 분석 : 체계적 고찰

유영대(Young-Dae Yoo),양회송(Hoe-song Yang),정찬주(Chan-Joo Jeong),강효정(Hyo-Jung Kang),김민규(Min-Kyu Kim) 대한심장호흡물리치료학회 2021 대한심장호흡물리치료학회지 Vol.9 No.2

Purpose : This study aimed to analyze the effectiveness of inspiratory muscle training(IMT) studies for stroke patients conducted over the past 10 years(2011–2020) in Korea. Methods : Previous literature was electronically searched using the RISS, KISS, KCI, and NDSL databases. Tree databases were searched for stroke IMT articles. A total of 12 studies were selected according to the PRISMA guidelines, and the Jeong’g qualitative evaluation criteria were used to refer to the checklist presented by the Scottish Intercollegiate Guideline Network. Results : Twelve studies met the criteria. In a qualitative evaluation on the papers, one study scored 8 out of 10, seven scored between 6 and 7, and four scored 5. Intervention sessions were conducted between 20 and 30 min, each at a frequency of three to five sessions per week, for a total of 4–8 weeks. The results indicated that IMT effectively improved respiratory function, physical activity, and respiratory muscle function in stroke patients. Conclusion : IMT was found to have a positive effect on respiratory function, physical activity, and respiratory muscle function in stroke patients.

남성화를 보이는 여성에서 발견된 난소의 Steroid Cell Tumor 1예

조인호,정대훈,박영미,서영진,손영실,정철회,강영미,정수전,김영남,이경복,성문수,김기태 인제대학교 2006 仁濟醫學 Vol.27 No.-

Steroid cell tumor is a rare ovarian sex cord-stromal tumor which accounts for 0.1% of all ovarian tumors. Until now, only 4 cases have been reported in domestic literatures. Steroid cell tumor often secrets testosterone and presents virilization in adult women or precocious puberty in children. Treatment is often performed by surgical removal, adjuvant chemotherapy and radiation, but completely accepted treatment was not existed. We experienced a case of steroid cell tumor, which was manifested by typical virilization in a 43-year old patient, who was previously performed hysterectomy and unilateral oophorectomy. So, we present with a brief review of the literatures.

Chloroform 만성 중독으로 인한 간병변에 대한 병리학적 연구

정호석,강대영 忠南大學校 癌共同硏究所 1991 癌共同硏究所 硏究誌 Vol.1 No.1

In an attempt to elucidate the pathological effects of chloroform(CHCl_(3)) administration, the present study was undertaken in male Sprague-Dawley rats. Evidence for the existence of hyperplastic nodules, oval cells, bile duct or ductular proliferation, and liver cirrhosis was examined, and the number of dysplastic cells were evaluated, emphasizing especially on the difference among the several groups. Rats were administered 300mg/kg or 600mg/kg of chloroform(CHCl_(3)-corn oil 1:4 solution) intraperitoneally, and then twice injected weekly for 36 weeks. The control animals were given as similar volume of saline or corn oil, respectively. The animals were sacrificed in 3rd, 6th and 9th month after chloroform injection. The histopathologic changes in the liver of the control and experimenal groups were noted as follows: 1) The hyperplastic nodules in the 600 mg/kg chloroform treated group were more prominent than those of the 300 mg/kg chloroform treated group in the number and size. 2) The number of dysplastic hepatocytes were increased gradually as the experiment continiued. The incidence of dysplastic hepatocytes was 45.5% in the 300 mg/kg treated group and 70.6% in the 600 mg/kg treated group. 3) Oval cells appeared in the early days of the experiment (3rd month) and then gradually decreased in number. 4) The degree of severity of liver cirrhosis and bile duct or ductular proliferation gradually increased as the experiment continued. Incidence of liver cirrhosis and bile duct or ductular proliferation was 31.8% in the 300 mg/kg treated group and 64.7% in the 600 mg/kg treated group, respectivley. 5) Incidence of the chloroform induced hepatoma was 5.9%(1 out of 17 rats) in the chloroform 600 mg/kg treated group, and the hepatoma spread to the liver, followed by metastasis to the omentum and ileum. 6) Light microscopically, some hepatic lobules revealed some foci of vacuolated or clear hepatocytes. Electron microscopically, they contained fat droplets. Others also contained increased number of mitochondria or distorted mitochondria. In summary, the result obtained by the present study indicates chloroform induced hyperplastic nodules, liver cell dysplasia, oval cell proliferation and liver cirrhosis, and secondarily induced hepatoma.

Resazurin Disc 우식활성검사의 척도 세분에 따른 타당도 변화에 대한 연구

정영석,이광희,김대업 大韓小兒齒科學會 1998 大韓小兒齒科學會誌 Vol.25 No.1

The purpose of study was to investigate the variation of validity of the Resazurin Disc Caries Activity Test by subdivision of the measuring scale of the test. The 3-level color scale of RD test was revised and 4- and 5-level scales were made. The subjects of study were preschool children, 227 for 3-level group, 238 for 4-level group, and 256 for 5-level group. The validity of the RD test using each scale was analyzed by using the caries experience as criteria. The results were as follows:

國際廣告의 標準化와 適應化戰略에 관한 硏究

鄭大榮 호남대학교 1993 호남대학교 학술논문집 Vol.14 No.-

International promotion has generated considerable discussion since the 1960s, mainly concerning whether international companies should adapt or standardize their foreign advertising messages. International advertisers are often faced with the problem of whether, to what extent, and in which manner advertising should be adapted or changed prior to deployment in diverse foreign markets. That is, under what circumstances should advertising campaigns be standardized or localized, and to what extent? Proponents of the standardized approach advance various reasons to support their viewpoint. First, there is the cost savings. Once an advertising concept is developed, it can be transferred to other nations with minor additional Second is the realization of economies of scale made possible by the centralization of world-wide advertising authority in the home office. Third, standardization permits full utilization of home office advertising expertise hard won on the fiedl. Fourth, it prevents the generation of disparate messages in different nations which eventually may blur the established image of the product. Fifth, the common approach to advertising ensures proper concern for corporatewide objectives in promoting the product. Finally, similarities in the across nations justify the standardized approach. On the other hand, advertising theorists supporting the adaptation of commercial messages suggest that advertising is one of the most difficult marketing elements to standardize, sometimes because of the legal restrictions that require changes in copy or make certain media unavailable, but more often because of cultural differences. The determination of international advertising strategy is not a simple matter of choosing between standardization and adaptation. Conditions differ from nation have been successfully transferred, another campaign might flop in the same country. Besides, even where adaptation appears satisfactory, companies naturally do not want to give up the benefits of standardization. To resolve the problem, strategy should be formulated after careful analysis and consideration.

Phenobarbital 및 인진호투여가 四鹽化炭素에 依한 急性 中毒性 肝病變에 미치는 影響에 關한 病理組織學的 硏究

鄭昊錫,姜大榮 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.1

Carbon tetrachloride, a potent hepatotoxic agent, is mainly metabolized in the liver, and its hepatotoxic action is influenced by the administration of phenobarbital or artemisia messerschimidtiana besser var. viridis(artemisia). Artemisia was used as folk medicine for the treatment of hyperbilirubinemia or patient with acute hepatitis. Sprague-Dawley rats(male and female) were administrated with 2 ml of carbon tetrachloride (CCI_4-olive oil 1 : 4 solution) intraperitoneally, after being anesthetized by ether. After 24 hours, phenobarbital(50 mg/kg/day) and artemisia (0.6 ml/kg/day) were admin istrated intraperitoneally for 3 days. Food was withheld 12 hours before CCI_4, administration. 7 animals of each group were sacrificed at 4th, 5th, 6th and 7 th day after CCI_4 injection. The histopathological changes in the liver cells of the control and experimental groups were noted as follows; 1. Vacuolar degeneration of the hepatic cells of CCl_4-phenobarbital administrated rats showed more marked in degree than the control, and that of CCl_4-artemisia administrated rats is milder than the control. 2. Fatty change of the hepatic cells of CCl_4,-phenobarbital administrated rats showed more marked in degree than the control, and that of CCl_4-artemisia administrated rats is milder than the control. 3. The necrotic changes of the hepatic cells of CCl_4,-phenobarbital administrated rats showed more marked in degree and remained longer than the control. Temporarily, that of CCl_4-artemisia administrated rats showed more marked in degree than control, but early recovered.

하수에서 분리한 합성세제 분해균의 특성

정민선,전진경,정영건,이해경,권오진,지원대,김관배 嶺南大學校 環境問題硏究所 1993 環境硏究 Vol.13 No.1

대구시와 경산시의 하수에서 음이온계 합성세제인 sodium dodecyl sulfate(SDS)와 sodium dodecylbenzene sulfonate(SDBS)를 유일한 탄소원으로 이용하는 균주 289종을 분리하고 이중 합성세제 분해력이 강한, 그람음성 간균으로 운동성인 8균주를 선정하여 그 선정균들의 특성을 조사하였다. 선정균은 40℃ 이상에서는 생육하지 못하였으며 생육 최적 pH는 균주간에 다소 차이가 있었으며 pH 4.0 이하에서는 선정균 모두 생육치 못하였다. 질소원으로는 SDS분해균의 생육에는 potassium nitrate가, SDBS 분해균의 생육에는 soytone이 좋았다. SDS 분해균인 DS-3, 6, 8, 24 및 SDBS 분해균인 BS-7, 8은 세제농도가 5.0% 이상에서도 생육이 가능하였다. 선정균들은 tetracycline에 감수성이 강한 것으로 나타났지만 penicillin에는 강한 내성을 띠는 것으로 나타났고, ??와 ??금속이온은 모든 선정균들의 생육을 억제하는 것으로 나타났다. On purpose to isolate the organisms, which would utilize detergents(sodium dodecyl sulfate, SDS and sodium dodecylbenzene sulfonate, SDBS) as a sole carbon source, from the waste water of Kyungsan and Taegu city 289 strains were isolated. Among them 8 strains, which are gram negative rods with motility and produce strong enzyme to biodegrade the synthetic detergents, were selected. The characteristics of them were investigated as follows, 8 strains were failed to grow above the temperature of 40℃ and below the pH 4.0 even though they have variable optimum pH. Potassium nitrate was very effective for the growth of SDS-biodegradable strains and soytone was effective for the growth of SDBS-biodegradable strains as a sole nitrogen source. Among 8 strains especially DS-3, DS-6, DS-8 and DS-24(SDS-biodegradation strains) and BS-7 and BS-8(SDBS-biodegradation strains) could grow above 5.0% of detergent concentration. All of 8 strains were very sensitive to tetracycline but resistant to penicillin. Selected 8 strains were inhibited by metal ions of ??(0.156mg/㎖) and ??(0.156mg/㎖).

國際마케팅의 價格戰略에 관한 硏究

정대영 호남대학교 2000 호남대학교 학술논문집 Vol.21 No.1

Prices determine the total revenue and to a large extent the profitability of any business. Because of the crucial importance of pricing, top management often plays a significant role in marketing pricing decisions. Top management must decide the strategic significance of pricing in marketing mix. The general rule of pricing is that over the long-run, prices must exceed costs and that prices may never exceed those of the competition. There is no absolute maximum price, but for any customer, price must correspond to the customer's perceived value of the product. The aim of most marketing strategies is to set a price that corresponds to the customer's perception of value in the product and at the same time dose not leave money on the table, so to speak. In other words, the objective is to charge what a product is worth to the customer and to cover all costs and provide a margin for profit in the process. International pricing is complicated by the fact that an international business must conform to different rule-making bodies and to different competitive situations in each country. Both the countries and the competition are constraints on pricing decisions. Each company must examine the market, the competition, and its own costs and objectives and local and regional regulations and laws in setting prices that are consistent with the overall marketing strategy.