응급 자궁경부봉축술 2 예

안치석,안영준,안광화,이철규,신향미,정은환 대한산부인과학회 1995 Obstetrics & Gynecology Science Vol.38 No.10

최근 저자들은 경관이 50%이상 소실되고 2-5cm정도 개대되었으며 양막이 질강내로 탈출된 2명의 진행성 자궁경관 무력증 산모에서 복부를 통한 양수제거로 양막내압을 줄이고 부풀린 foley catheter로 양막을 자궁강 안으로 밀어올린 후 McDonald 술식으로 응급봉축술을 시행 하여 임신기간을 충분히 연장하고 생존아를 분만시킨 경험하였기에 문헌적 고찰과 함께 보고하는 바이다. Emergency cerclage may be defined as that performed in the setting of advanced cervical dilation with bulging or "hourglass" membranes. Two patients with bulging or hourglass membranes and marked cervical dilation in the second trimester were treated with emergency cerclage after transabdominal amniocentesis. pregnancy was prolonged for a sufficient time to deliver viable fetuses in both patients. the lack of significant maternal morbidity combined with the results for the fetus-infant supports further efforts in this area.

Mechanical Ileus Associated Feeding Jejunostomy after Liver Transplantation

CS Park,SG Lee,S Hwang,KH Kim,CS Ahn,DB Moon,TY Ha,GW Song,DH Jung,GC Park,YD Yoo,PJ Park,YI Choi,SY Yoon,JM Namgung,SW Jung,HW Park,HJ Lee 한국간담췌외과학회 2010 한국간담췌외과학회 학술대회지 Vol.2010 No.4

내장탈출아 2예

안진상(CS Ahn),김창만(CM Kim),김대윤(DY Kim),이재윤(JY Lee) 대한산부인과학회 1981 Obstetrics & Gynecology Science Vol.24 No.6

저자들은 27세 초산부가 임신 32주에 분만한 내장탈출아 1예와 24세 경산부가 임신 42주에 분만한 내장 탈출아 1예를 경험하였기에 간략한 문헌고찰과 아울러 증례를 보고하였다. Omphalocele is a rare congenital anomaly. Recently, authors experienced two cases of omphalocele at Fatima Hosptal. One case was noted eviscerated intestine embrassed by peritoneal sac through the defected area of the abdominal wall. The baby was expired immediately after birth because of possible R.D.S . The other case was found the bowels including stomach protruding through the defected area of the abdominal wall (7cm in width) . Author report two cases of these omphalocele with reviewing some literature.

Inhibitory effects of the extract from Quercus dentata gallnut against plant virus infection

Kwon, SB.,Shin, JE.,Ahn ,SY.,Yoon, CS,Kim, BS 한국유기농업학회 2011 韓國有機農業學會誌 Vol.19 No.S

Pepper mild mosaic virus (PMMoV) and cucumber mosaic virus (CMV) are important pathogens in various vegetable crops worldwide. We have found that methanol extracts of Quercus dentate (Daimyo Oak) gallnut strongly inhibit PMMoV and CMV infection. Based on this result, the inhibitor named as "KN0912" formulated from the extract of Q. dentate gallnut was tested for its inhibitory effects on PMMoV or CMV infection to each local lesion host plant (Nicotiana glutinosa; PMMoV, Chenopodium amaranticolor; CMV). Pre-treatment effect of KN0912 against infections of each virus to local host plant was measured to be 75. 1:±0. 5-97. 5±1. 5% to PMMoV and 70.6±2.2-99.0±1.0% to CMV in 1-10mg/ml conc. and the absorption effect of the antiviral composition of KN0912 to the inside of tobacco leaves tissue, was inhibited by 55.7% to PMMoV and 63.8% to CMV. The persistence of KN0912 treatment was maintained until after the 3 days high inhibitory effect by 98% to PMMoV and by 95.1% to CMV. Inhibitory effects on systemic host plants of KN0912 were measured to be 80-90% to PMMoV and 60-75% to CMV. From the change of morphological characteristics of PMMoV particles under EM, we are tentatively suggested that one mode of action of KN0912 is inactivation due to the destruction of virus particles.

Evaluation of PPARa Agonism of DY-105359 in Vitro and in Vivo

AHN BN,SHIN CY,KIM MK,SON MH,KIM JK,MOON HS,LIM JI,KIM SH,BAE MH,LEE CH,PARK CS 大韓藥學會 2006 大韓藥學會 總會 및 學術大會 Vol.2006 No.2

자궁내막증 환자에서 항자궁내막 항체에 관한 연구

안치석,이경희,이진용,장윤석,문신용,김정구,김석현,윤병구 대한산부인과학회 1992 Obstetrics & Gynecology Science Vol.35 No.1

The cause of endometriosis has remained controversial. Recent investigation have focused on a possible role of the immune system in etiology and pathophysiology of endometriosis. Autoantibodies against endometrium have been demonstrated in the serum of women with endometriosis using immunodiffusion, passive hemagglutination and immunofluorescence. We investigated the presence of antiendometrial antibody in the sera of 63 women with endometriosis. The control group included the sera from 31 pregnant women and 29 fetal umbilical cords. Antiendometrial antibodies were assayed by passive hemagglutination. Antiendometrial antibody levels (mean±SEM) were significantly higher in the study group (51.0±10.1) than in the control group (3.9±0.6). Thirty-seven out of 63 patients (58.7%) tested positive, while all of the control group negative. In the study group, however, there was no difference in autoantibody levels by AFS stage : 33.7±10.7 in stage I, 30.3±6.0 in stage Ⅱ, 75.5±38.5 in stage Ⅲ, and 59.0±15.2 in stage Ⅳ. A positive rate of passive hemagglutination assay revealed no difference by severity of the disease : 46.2% in stage Ⅰ, 61.5% in stage Ⅱ, 66.7% in stage Ⅲ, and 60.0% in stage Ⅳ. There results suggest that serum antiendometrial antibody assay is specific and valuable for the diagnosis of endometriosis. The cause of endometriosis has remained controversial. Recent investigation have focused on a possible role of the immune system in etiology and pathophysiology of endometriosis. Autoantibodies against endometrium have been demonstrated in the serum of women with endometriosis using immunodiffusion, passive hemagglutination and immunofluorescence. We investigated the presence of antiendometrial antibody in the sera of 63 women with endometriosis. The control group included the sera from 31 pregnant women and 29 fetal umbilical cords. Antiendometrial antibodies were assayed by passive hemagglutination. Antiendometrial antibody levels (mean±SEM) were significantly higher in the study group (51.0±10.1) than in the control group (3.9±0.6). Thirty-seven out of 63 patients (58.7%) tested positive, while all of the control group negative. In the study group, however, there was no difference in autoantibody levels by AFS stage : 33.7±10.7 in stage I, 30.3±6.0 in stage Ⅱ, 75.5±38.5 in stage Ⅲ, and 59.0±15.2 in stage Ⅳ. A positive rate of passive hemagglutination assay revealed no difference by severity of the disease : 46.2% in stage Ⅰ, 61.5% in stage Ⅱ, 66.7% in stage Ⅲ, and 60.0% in stage Ⅳ. There results suggest that serum antiendometrial antibody assay is specific and valuable for the diagnosis of endometriosis.

자궁경부암에서 맥관형성의 의미

안치석,성노현,정은환 대한산부인과학회 1996 Obstetrics & Gynecology Science Vol.39 No.2

본 연구결과 자궁경부암 환자군에서 factor VIII을 이용한 미세혈관의 발현정도는 대조군과 비교해 200배율하 현미경하에서만 각 군간에 통계학적 차이가 있음을 확인할 수 있었으며, 여러 임상적 예후인자 혹은 생화학적 예후인자와의 상호 관련성 미비 등의 문제때문에 자궁경부암과 맥관형성과의 연관성을 아직 확인할 수 없어 추후에 계속적인 연구가 필요하리라 판단된다. Angiogenesis, the formation of new vessels, has been associated with tumor growth. Experimental evidence suggests that the neovascularization increases the opportunity for tumor cells to enter the circulation and is correlated with metastasis. To investigate if angiogenesis is a related factor in carcinoma of the uterine cervix, we counted microvessles and graded the density of microvessels in 30 paients with squamous cell carcinoma of the cervix. Tumor sections were stained immunohistochemically with factor VIII to identify all vessels. The microvessels were counted and graded in the most intense areas of neovascularization by light microscopy. Microvessel counts in patients with wquamous cell carcinoma were significantly different from those of normal cervix and chronic cervicitis in 200x field microscopy: 22.43 vs. 6.57 and 10.93 (p=0.0182). There was no correlation between microvessel count and clinical parameters such as tumor size or clinical FIGO stage. This study suggests that tumor angiogenesis could be involved in squmous cell carcinoma of the uterine cervix. However, microvessel counts may not be a prognostic value in patients having risk factors for poor clinical outcomes.

태아 복수액을 이용한 신속 염색체검사

안치석,송형근,안광화,정은환,강석원 대한산부인과학회 1995 Obstetrics & Gynecology Science Vol.38 No.8

저자들은 임신 33^(+5주)에 심한 복수와 음낭수종이 있는 태아의 복수액을 채취하여 기존의 양 수 세포 배양법을 변형한 방법으로 염색체검사를 시행하여 성공하였으며 제대혈을 이용한 염색체검사와 동일한 핵형을 얻을 수 있었다. 따라서 복수가 있는 태아에서 적절한 산과적 치료를 위해 신속한 염색체검사 결과가 필요하나 제대혈 채취가 어려운 경우 복수천자에 의한 태아 체액을 이용하면 정확한 염색체검사 결과를 얻을 수 있으므로 기술적으로 어려운 제대혈 채취를 대치할 수 있을것으로 사료된다. 또한 임파구 배양법을 이용하면 더욱 빨리 결과를 얻을 수 있어서 산과적 치료방침의 결정에 매우 유용할 것으로 사료된다. Ultrasound-guided fetal paracentesis and cordocentesis were performed in a fetus who had massive ascites and hydrocele in third trimeste. Cells from fetal ascites were processed like amnionic fluid for karyotyping and successful result was obtained within 10 days. our present study suggests that fetal ascitic fluid may provide rapid fetal karyotyping and guideline to obsteric management in selected patients.

양막대로 인한 무뇌증과 후경부 피부결손

안치석,노재숙,김학순,정은환 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.8

The association of major fetal malformations with amniotic bands has been known for many years. However, we are apt to ignore the possibility of amniotic band syndrome. In this case, fetal anencephaly was diagnosed at 17 weeks, menstrual age on the basis of sonographic findings. Following pregnancy termination, examination of the abortus rev- ealed the cerebral remnant which is similar to that found in dysraphic anencephaly, but collateral evidence of amniotic band was found. Therefore, when confronted with severe cranial or cerebral malformation amniotic band syndrome should be in the differential dia- gnosis.

초기임신에서 혈중 β-hCG , Progesterone , 17α-hydroxyprogesterone의 농도와 황체 크기의 임신주수에 따른 변화양상

안치석,노재숙,김학순,정은환,강지연 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.4

Pregnancy maintenance is dependent on the presence of a functional corpus luteum (CL) for a few weeks after implantation. However, the factors responsible for the rescue of the CL during early pregnancy have not been fully clarified. This study was designed to evaluate whether the change in size of the CL of early pregnancy, serum concentration of progesterone, 17α-hydroxyprogesterone, or β-hCG correlated with the gestational age or were predictive of pregnancy outcome. We retrospectively analysed thirty-six women between 4~9 weeks` gestation. All women underwent transvaginal ultrasound measurement of the CL size and gestational sac(or crown-rump length). Blood was drawn from each patient on the day of the ultrasound examination to measure hormone concentration. Fifteen women experienced vaginal bleed ing and abdominal pain. Among them, four women were aborted. There was no significant positive correlation between CL size and serum progesterone, 17α-hydroxyprogesterone or β-hCG both in normal and abnormal pregnancy. A positive correlation was observed between the gestational age and progesterone or β-hCG in normal pregnancy, but not in abnormal pregnancy(threatened or spontanous abortion). In conclusion, close correlation between the gestational age and serum concentration of progesterone or β-hCG may reflect the normal function of CL. Therefore, abnormal response of CL or abnormal production of β-hCG cause a disturbance in progesterone secretion leading to the abnormal pregnancy.