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최중묵(Jung Muk Choi),한동화(DH Han),이영진(YJ Lee),정병환(BH Jung),최규하(Gyu Ha Choe) 전력전자학회 2010 전력전자학술대회 논문집 Vol.2010 No.7
본 논문은 연료전지용 PCS를 계통에 연계하는 과정을 보다 심도있게 진행하기위하여 배전계통을 모의 시뮬레이터로 구현 하였다. 제작된 시뮬레이터를 바탕으로 각배전반의 전력품질과 다수 PCS와 계통과의 전력분배를 실험한다.
움직이는 물체의 탐지에 있어서 대비 감민도와 시력의 역할
김정오(Jung-Dh Kim),박창호(Changho Park),이상훈(Sang-Hoon Lee) 서울대학교 심리과학연구소 1993 心理科學 Vol.2 No.1
본 연구의 두 실험들은 정현파 격자무늬(sine wave gratings) 자극 패턴들을 사용하여 시력과 대비감민도가 정지된 물체나 그 크기가 시간에 걸쳐 변하는 물체의 탐지에 미치는 상대적 영향을 검토하였다. 두 실험에 걸쳐 일관된 결과는 적어도 랜돌트 링 표준시력검사로 측정된 사람의 시력이 물체의 비교나 크기 판단반응의 속도나 정확성에 아무런 영향력을 미치지 않음을 보여주었다. 이와는 대조적으로 판단해야할 물체를 이루는 공간빈도와 대비 수준이 사람들의 수행에 체계적으로 영향을 미쳤다. 실험1에서는 두 비교 패턴의 공간빈도가 2일 때 동일 판단을 내리는 반응시간이 가장 느렸다. 실험2에서는 크기가 시간에 따라 달라지는 정현파 격자무늬에 있어 특정 크기를 탐지할 때 공간빈도가 4인 경구가 다른 자극 조건들에 비해 더 느린 탐지반응 시간을 보였다. 이러한 결과들은 종합적으로 정적 물체이든 동적 물체이든 시력과는 무관하게 대비감민도가 매우 중요함을 보여준다. Using sinewave gratings varied in contrast and spatial frequency, two experiments explored relative effects of contrast sensitivity and visual acuity on detecting either stationary or moving targets. Visual acuity, as measured by a Landolt Ring test, did not affect the subjects' decision times and accuracy, whereas spatial frequency and contrast did. For the same response, the longest reaction time was observed for the sinewave gratings of 2 cycles per degree. When the subjects were required to detect sinewave gratings whose size changed over time, those gratings of 4 cycles per degree showed the slowest reaction times. The pattern of results of two experiments indicate that regardless of visual acuity, the subjects' contrast sensitivity is very important in detecting various objects, be they moving or not.
철분공급이 임신부와 태아의 혈청 Ferritin헤모글로빈 , 혈청철 및 철결합능에 미치는 영향
정은숙(ES Jung),송기창(KC Song),정운남(WN Jung),나덕진(DJ Rah),김대훈(DH Kim),나종구(JG Na) 대한산부인과학회 1989 Obstetrics & Gynecology Science Vol.32 No.7
1987년 10월부터 1988년 2월까지 5개월간 가톨릭의과대학 부속병원에서 정상분만한 임신부 54명과 그에게서 출생한 정상신생아 54명에서 혈청 ferritin, 혈색소, 혈청 철, 총 철결합능을 측정하여 다음과 같은 결론은 얻었다. 1. 임신부의 혈청 ferritin치는 평균 23.7+-21.7 ug/l, 혈색소치는 평균 11.4+-1.8g/dl, 혈청 철은 평균 121.0+-80.0ug/dl이고 총 철결합능은 평균 446.9+-133.9ug/dl이엇다. 이들에서 출생한 태 아의 제대혈의 혈청 ferritin치는 평균 118.0+-62.1ug/dl이고, 총 철결합능은 평균 289.9+-86.3ug/dl이었다. 임신부와 제대혈의 검사치를 비교하면 혈청 ferritin, 혈색소, 혈청철은 모두 제대혈에서 5배, 1.3배, 1.6배로 높았다. 2. 임신부의 ferritin치에 따라 구분해보면, ferritin치가 12ug/l이상인 군은 31명(58%)이고 그미 만인 군은 23명(42%)으로 임신부의 혈청 ferritin치와 제대혈청 ferritin치사이에는 유의한 상관 관계가 있었다. 그러나 임신부의 혈청 ferritin치와 제대혈의 혈색소치, 혈청 철사이에는 상관 관계가 없었다. 3. 임신부의 혈색소치를 기준으로 혈색소치가 11g/dl이상인 군과 그 미만인군으로 나누어 비 교해 보면 임신부의 혈색소치와 제대혈의 혈색소치, 혈청과 혈청 ferritin사이에 유의한 상관 관계가 없었다. 4. 철분공급에 따른 차이를 보면 철분공급을 받은 경우에 임신부와 제대혈에서 모두 혈청 ferritin의 상승을 보였으나 제대혈의 혈색소치와 혈청철에는 유의한 차이가 없었다. 5. 임신부의 연령, 임신회수, 임신주수와 태아체중에 따른 철분대사 기준의 변화는 없었다. Measurements of serum ferritin and other hematologic laboratory indices about iron metabolic state were done in 54 paired maternal and cord blood, and 17 of these 54 women had taken iron supplement during pregnancy. These values were analyzed by parameter of maternal serum ferritin hemoglobin, iron supplement, and following results were obtaiend. 1. Average value of maternal serum ferritin was 23.7+-21.6 ug/l and that of hemoglobin was 11.4+-1.8 g/dl and those for serum iron and TIBC were 121.0+-80.0 ug/dl and 446.9+-133.9 ug/dl respectively 2. Values of cord serum ferritin hemoglobin serum iron were higher than maternal values especially cord serum ferritin was about 5 times higher than maternal serum ferritin 3. There was linear correlation between maternal serum ferritin and cord ferritin . But there was no correlation between maternal serum ferritin and cord ferritin hemoglobin serum iron and TIBC. 4. There was no correlation between maternal hemoglobin and cord hemoglobin serum iron and serum ferritin. 5. By iron supllement, the average values of maternal hemoglobin , maternal ferritin and cord serum ferritin were increased. 6. Iron hematologic indices were not changeable by maternal age, parity gestational week and fetal weight.
Pathological Analysis of Dysplastic and Malignant Nodules in 21 Explant Livers
Jung,ES,An,BM,Park,DH,Kim,BS,Choi,JY,Lee,CD,Park,YM,Han,NI,Byun,BH,Kim,BK,Bae,SH,Yoon,SK,Baek,JH,Byun,JY,Kim,DG,Kim,IC,Cha,SB 가톨릭중앙의료원 가톨릭암센터 1998 암심포지움 Vol.- No.2
동족 간이식이 보편화됨에 따라서 전체간을 분석할 수 있게 됨으로서 간암 및 전암병변에 대한 방사선학적, 병리학적 연구가 활발하게 진행되고 있다. 간경변증은 간암의 가장 중요한 선행질환으로서 이에 대한 병리조직학적 연구는 간암발생의 단계적 발전과정과 관련된 기전을 밝히는데 중요한 단서를 제공할 것으로 시사된다.
시험관아기 시술시 정자직접주입법을 이용한 2146 예의 임상 결과
최동희,윤태기,차광열,한세열,정형민,엄기붕,고정재,오종훈,손지온 대한산부인과학회 1998 Obstetrics & Gynecology Science Vol.41 No.1
Since Palermo and coworkers(1992) reported the first ICSI-baby, ICSI has been widely accepted as a treatment of male factor infertility. ICSI techniques have also been used to treat abnormal semen parameters in order to overcome fertilization failures and to increase clinical outcomes. From January 1994 to December 1996, 2146 ICSI cycles were performed at the Infertility Center of Cha General Hospital and we achieved a 75.1% of fertilization rate with 713 subsequent pregnancies(34.8%). The ICSI fertilization rate using 1-day old oocytes which failed to fertilize using conventional IVF method was lower than the ICSI fertilization rate using fresh oocytes(75.7% vs 65.9%). However, we achieved 13 pregnancies out of 125 embryo transfers from the total fertilization failure group. There was no statistical difference in the fertilization rates using normal semen or semen with single defect, but statistical differences were observed between normal semen and semen with two or more defects. No statistical difference was found in pregnancy rates between normal and defective semen groups. In our MESA, PESA and TESE programs, we achieved high fertilization rates(69.2∼82.5%) and a 45.8%(mean) pregnancy rate. Categorizing the female patients by age, ie., ≤29, 30∼34, 35∼39, ≥40, fertilization rates were consistently in the range of 74.5∼ 75.7%, but pregnancy rates significantly decreased in patients older than 35 yrs(31.3%) or 40 yrs(14.2%). Of the 713 pregnancies, we were able to obtain follow-up information of the babies in 527 cycles, of which we found 8abnormalities.
자궁내막증 환자의 복강액이 생쥐배아발달에 미치는 영향에 관한 연구
배도환,허민,이상훈,정병준,윤연정,장현정 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.4
Endometriosis affects up to 5 million women in the united states. The number of cases observed at any time is 1 in 15(7%) women in the reproductive age range. Infertility occurs in as many as 30% to 40% of cases. Anatomical compromise with failure of oocyte capture and transport is an eviednt explanation for infertility in women suffering from advanced(stageⅢ/Ⅳ) endometriosis. In contrast, the pathophysiology in couples suffening from mild to moderate endometriosis as a sole infertility diagnosis is poorly understood.l Research over the last decade indicates that women with endometriosis suffer from excessive activstion of immunocompetent cells within the pelvis. In experimental paradigms, adversd effects of a peritoneal fluid on the reproductive process of the endometriosis patients can be demonstrated and include: (1) Phagocytosis of sperm (2) Decreased sperm motility (3) Alteration of sperm-egg interactions (4) Failure of oocytes capture by the fimbria and (5) Impeded embryo development. These data raise the possibility that the intraperitoneal inflammatory process observed in women with endometriosis may be responsible for the associated infertility. The purpose of this study was to evaluate the effect of peritoneal fluid(PF) from patient with moderate endometriosis on mouse embryo development. PF was aspirated from the posterior cul-de-sac at laparoscopy and centrifuged, and the cell-free superantant was not heat-inactivated and not filtered. Fifty percent PF in human tubular fluid(HTF) media was prepared as a study group. The control group consisted of PF with a nonendometriosis and of 0.5% bovine serum albumin and HTF. The in vitro fertilization was performed with these culture media. We were observed distribution of embryo under the microscopy at 24 hours, 72 hours, 92 hours and 120 hours after insemination. The 2-cell embryonic stages in the study group(254 ovums) and those in the control group(247 ovums) at 24 hours were 50.4%, 70.4%, respectively. At 72 hours, the embryonic stages of both groups were reached the morula stage. At 72 hours, only 7.0% of the embryos in the study group reached the hatching, versus 55.7% in the control group.(p$lt;0.001). At the 120 hours, 100% of embryos in study group were degenerating, versus only 13.2% in the control group. As a result, the peritoneal fluid of the endometriosis patients exert an adverse influence on early reproductive performance, especially inhibiting embryo development. The peritoneal fluid may be as a mediator in the pathogenesis of endometriosis associated subfertility.