상완골 간부 골절의 골수강내 금속정과 금속판 내고정술에 의한 치료의 임상 체험

변기용,이상용 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

Humeral Shaft Fracture had been treated by conservative method successfully. Rich blood Supply by bulky soft tissue envelope make it possible to get bony union with less incidence of nonunion and malunion. Nowadays, multiple trauma, needs for early ambulation, patients need for short hospital stay and many surgical indications favor operative treatment. Open reduction and internal fixation by plate and screw or fixation by intramedullary nail is widely used surgical technique. But, when open reduction and internal fixation by plate is carried out, the periostium and soft tissue attachments must be stripped off and operative time needed to be longer and when intramedullary fixation method carried out , postoperative shoulder joint stiffness and pain is problem. We managed 40 cases of humeral shaft fracture, 26 cases were treated by open reduction and plate fixation methods 14 cases were treated by closed reduction and intramedullary nail fixation method from March 1992 to December 1994. The results were as follows;1. Intramedullary fixation methods may needs longer bony union time compare to the plate fixation method but it required short operation time and it enable the patient to early joint motion. so we thought this method is suitable for the patient who have multiple injuries and need for early ambulation. 2. Among the intramedullary nail fixation cases, painful limitation of shoulder motion is noticed. this complication was more common in the cases with protruded proximal end of the nail.

슬개골 연골 연화증의 진단 및 관절경적 치료(일일 수술)

변기용,권순태,정상윤,이광진 충남대학교 의과대학 지역사회의학연구소 2000 충남의대잡지 Vol.27 No.2

Purpose : To evaluate the efficiency of MRI in the diagnosis of chondromalacia patella and the result of Day surgery using LASER. Material and Method : This is a retrospective study of 24 patients(25 cases) of chondromalacia patellae from April, 1995 to April, 1996. We used 1.5T MRI(GE Signa Avantage, Milwaukee, WL, U.S.A) as a diagnostic tool, and compared the site, shape and degree in MRI with arthroscopic findings. Arthroscopic chondroplasty was performed in the day surgery center using Ho-YAG LASER under local anesthesia, and the patients discharged and followed up. Result : In the diagnosis of chondromalacia patella, the sensitivity., specificity, accuracy and positive predictive value of MRI were 72%, 96%, 93% and 75% respectively. In the arthroscopic treatment using LASER, there were 20 cases of good and 5 cases of poor result, and there were no hemorrhagic effusion or reactive synovitis. Conclusion : In the diagnosis of chondromalacia patella, MRI revealed high sensitivity, specificity, accuracy and positive predictive value, but, the lesser degree of chondromalacia, the lower sensitivity and positive predictive value. Arthroscopic day surgery using LASER is effective in pain relief, cost-effective by short hospitalization period and has less complications such as hemorrhagic effusion or reactive synovitis. Thus, arthroscopic surgery using LASER in chondromalacia patella is thought as one of the useful methods of treatment.

Ilizarov 외고정기기를 이용한 슬관절부 분쇄상 관절내 골절의 치료

변기용,이상용 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.2

Intraarticular fracture of knee(tibial plateau or femoral condyle) occur primarily in a younger population and often the result of blunt trauma. Invasive treatment optioens have historically included a wide variety of surgical methodologies, but these treatments have been associated with significant complications such as joint stiffness, malunion, infection, loss of fixation, skin loss and amputation. these may be associated with lengthy operative procedure and extensile surgical approach through tenuous soft tissue envelope. So we applicate small wire circular external fixator in percutaneous fashion with minimal additional devitalization of bone, periosteal blood supply and endosteal blood supply. The authors analysed the 8 cases of intraarticular fractures of the knee joint that reduced by Ilizarov external fixator from April 1992 to August 1995. The fixator can be designed to compress the fracture gap to achieve bone to bone contact without additional bone grafting. Fracture gap secondary to malalignment can be corrected sequentially as bone union take place. The following result were obtained. 1. All fractures have healed and mean union time was 15.5 weeks. 2. If there is severe comminuted open fracture or soft tissue injury, open reduction and internal fixation method is inadequate. 3. In theses case, arthroscopic joint Line realignment and Ilizarov external fixator application can get good result.

외식프랜차이즈 가맹점의 갈등과 분쟁해결 사례연구

김기홍,정웅용,변준영 韓國仲裁學會 2005 중재연구 Vol.15 No.3

This study is for an example of arbitration of a dining out franchise company in Korea and frachise system currently is expanding and developing to international trade. The main reason for that is franchising has some benefits compared to the existing trades. Korean dining-out industry has largely developed for the past 20 years, but there are little world-class company of the industry, because dining-out industry should go for qualitative as well as quantitative growth at the same time. Korean dining-out industry has adopted licensing and joint-venture among growth strategies, but the franchise system among them seems to have taken its place as a representative strategy for management to develop dining-out industry. The history of Korean dining-out franchise industry is very short and it is true that we have no a management philosophy of accompanying growth with franchise due to a short experiences and recognition of top management or managers and short-term strategy for branch expansion. For a brilliant growth of dininig-out franchise industry, to settle disputes through arbitration, in case of disputes taking place, is very important, because the franchise industry is a frequent-trading sector, requires expert-level knowledge, favors a closed examination and also needs a fast solution. As the franchise industry has been sharply growing around the world, there is more possibility of disputes, and various and complicated laws of the industry are related to disputes as well, so much more expert-level knowledge is required to solve disputes. Therefore, affiliated headquarters hope a disclosed settlement of their disputes and their any disputes should be fast settled for the benefits of affiliated members.

근위 경골 간단부 골절 치료 및 이중 금속판 사용의 의의

박찬희,변기용,이상용 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

Fracture of the proximal tibia caused by combination of vertical thrust and bending force are often associated with soft tissue injuries. The aims of treatment are to obtain good aligned bony union and mobile painless knee joint function, but there are many difficulties and problems to get those. An unstable proximal tibial fracture accompanied by a lateral plateau fracture can be stabilized with single lateral plate. But if fracture pattern includes significant medial comminution, lateral plate alone cannot restore medial proximal tibial buttress, and continuous knee joint motion may causes sagittal plan angulation of fracture site. In theses cases, we had applied lateral. plate and additional medial or ventral plate (double plates) and could get rigid fixation. We had performed 5 cases double plate fixation. there was no wound complication and through early joint exercise could restore normal knee joint ROM without angulation deformity. If severe soft tissue problem is combined, or it is a more than grade II open tibia fracture, rigid external fixator such as Ilizarov® was applied and it allowed fracture healing without wound infection.

후방십자인대 건열골절 : 자기공명영상 소견의 분석 Assessment of Magnetic Resonance Images

권순태,변기용,이광진 충남대학교 의과대학 지역사회의학연구소 1996 충남의대잡지 Vol.23 No.1

Purpose : To evaluate the injury mechanisms and associated injuries of avulsion fracture of the posterior cruciate ligament (PCL) on the MR images Materials and Methods : MR findings of twelve patients with avulsion fracture of the tibial attachment of the PCL were evaluated. Eight of the patients had fresh injuries and four, injuries with old. We assessed bone marrow contusion and associated injury with its type and extent. Five of the twelve patients were treated conservatively and seven, by surgical repair by means of wiring and/or screwing according to the size and extent of the fracture segment. Arthroscopy was undertaken in three patients with lipohemarthrosis and/or meniscus tear on the MRI. Results : Four cases of flexion injuries and three cases of hyperextension were suggested according to the bone contusion and associated injuries on the MR images. Tear of the media collateral ligament and popliteal tendon with avulsion fracture of the PCL were found in one and associated meniscus tear in two of the twelve patients, respectively. Rupture of the posterior capsule were demonstrated in the two patients with hyperextension injuries. Sprain of medial collateral ligament in three cases and lipohemarthrosis in two cases were noted. There show relatively isolated avulsed PCL injuries in eight cases (67%). Conclusion : We could suggested the mechanism of injury for the avulsion fracture of PCL according to the bone marrow contusion and associated injuries on the MR images. MRI is useful for the selection of appropriate treatment and surgical plan in the avulsion fracture of the PCL.

중부지역 대학생의 남녀평등의식에 관한 실태조사

최덕경,최동숙,강기정,유을용,변미희 한국청소년복지학회 2004 청소년복지연구 Vol.6 No.1

This study investigated gender eqalitarianism of university students. The purpose of this study was to offer basic information and desirable direction for the education program of student's sex-role indentity. The data collection was based on Korean Questionnaire of Gender Equality Perception developed by Korean Women Development Center. Its reliabilitv(Cronbach α) was .84. In this study.982 university students were sampled in Kyunggi, Gangwon and Chungchong provinces. T-test and One-way ANOVA was conducted with the SPSS 10.0 version program. The major findings of this study were as follow: First, university student showed the highest gender eqalitarianism in educational life field. But they have the lowest in social and cultural life field. Second, male university students showed lower gender eqalitarianism than female university students. Third. student who is middle or last in brother order showed higher than one who is first or only son. Forth, student who is grown up in urban showed higher gender eqalitarianism than one in country.

항갑상선제로 치료한 그레이브스병 환자의 관해예측인자

남일송,윤여일,김선규,김용현,이주영,목지오,윤석기,김철희,김영선,변동원,서교일,유명희 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

Background: Most cases of Graves' disease have been treated by antithyroid drugs in Korea. The major drawbacks of antithyroid drugs are the relative high rate of relapse and the inconvinience of long term therapy. Measurement of TBII and TRH stimulation test have been considered as the most reliable tests predicting relapse, but the predictive power is not high enough to use in clinical situation. This study was performed to find good prognostic indicators in Graves' disease patients after the discontinuation of antithyroid drug therapy. Subjects and methods : We restrospectively evaluated 96 patients with Graves' disease who showed normal TRH test at the end of antithyroid drug therapy and were followed for more than one year. Serum T3, T4, T3/T4 ratio, TBII, Anti-TPO Ab and TGAb levels were measured at the time of diagnosis and at the end of therapy. Two to three months after withdrawal of antithyroid medication, serum TSH and free T3 responses to TRH were examined. These parameters were compared between the relapse group and the remission group. Results : Among the 96 patients, 22 patients(22.9%) relapsed(Group Ⅱ) and 74 patients(77.1%) remained in remmision(Group Ⅰ). No significant difference was observed between the relapse and the remission group in clinical parameters, serum T3, T4, TSH, T3/T4 ratio, TBⅡ and Anti-TPO Ab determined before and after treatment. Serum TSH and free T3 levels measured after TRH stimulation were also similar in both groups. Serum TGAb levels determined at the end of treatment were significantly higher in the remission group(p<0.05). Relapse following the discontinuation of therapy occured within 24 months in 72.7% of the relapsed cases. After 24 months, relapse rate was reduced significantly. Conclusion : These results suggest that high serum TGAb levels could be a favorable prognostic indicator for the long term remission of Graves' disease treated with antithyroid drugs, and may suggest that Hashimoto's thyroiditis is combined with Graves' disease in those patients.

항균성 펩타이드인 Mastoparan B의 살조효과

서정길,김찬희,배윤정,문호성,김근용,박희연,윤호동,김창훈,변대석,홍용기,박남규 한국어병학회 2003 한국어병학회지 Vol.16 No.3

Mastoparan B (MPB)는 벌독으로부터 정제된 양친매성α-helical 구조를 취하면서 14개의 아미노산 잔기로 구성된 염기성 항균성 펩타이드로서 여러 가지 생물막과 작용한다. 본 연구에서는 우리 나라 연안의 적조 (HABs, harmful algal blooms)를 일으키는 4종의 적조생물 (Alexandrium tamarense, Chattonella catenatum)에 대한 MPB의 살조효과를 조사하였다. MPB의 4종의 적조생물에 대한 살조효과는 31.3㎍/㎖에서 세포의 lysis또는 ecdysis와 같은 형태로 현미경으로 관찰할 수 있었다. 또한 MPB는 C. marina 및 C. polykridorides에 대해서 A. tamarense와 G. catenatum보다 더욱 강한 살조효과를 나타내었다. 이러한 MPB의 HABs에 대한 살조효과연구는 새로운 살조물질을 개발하기 위한 자료가 될 것으로 생각된다. Mastoparan B (MPB), an antimicrobial cationic peptide isolated from the venom of the hornet Vespa basalis, is a basic amphipathic a-helical peptide composed of fourteen amino acid residues. In this study, we have investigated the algicidal effect of MPB against hatmful algae blooms (HABs) casative Alexandrium tamarense, Chattonella marina, Cochlodinium polykrikoides and Gymnodinium catenatum. The algicidal effect of MPB showed in the concentration of 31.3 ㎍/㎖ to 500 ㎍/㎖ against 4 HAB species and observed cell lysis or cell ecdysis by microscopy. MPB reacted more sensitive to C. marina and C.polykrikoides than A. tamarense and G. catenatum. The algicidal study of MPB against HABs will provides much insight into development of new algicidal substances.

The deficiency of Fryl gene induces neonatal lethality

Yong Sub Byun,Eun Kyoung Kim,Hae Rim Kim,Ju Sung Kang,Yu Rim Kim,Ju Young Lee,Min Young Lee,Sang Mi Cho,Ho Young Ghang,Ki Hoon Lee,Won Kee Yoon,Young Suk Won,Hyoung Chin Kim,Kyung Chul Choi,Ki Hoan Na 한국실험동물학회 2015 한국실험동물학회 학술발표대회 논문집 Vol.2015 No.8