LC 공진형 PWM 인버터를 이용한 X선 발생장치의 특성에 관한 연구

이성길,박수강,임홍우,조금배,백형래,임양수 조선대학교 에너지.자원신기술연구소 2002 에너지·자원신기술연구소 논문지 Vol.24 No.1

The conventional types of X-ray generators were bulky in physical size and heavy in weight, and the control accuracies of the output voltages were not always satisfactory. The high frequency switching inverter and converter technology on power conversion and control systems have been greatly closed up introducing power semiconductor devices. In this paper, the newly developed converter to take the balance of the output voltage versus the ground are also presented in detail to decreasing the volume and the weight of high voltage transformer and to stabilize ripple. This converter consists of the two independent L-C series resonant circuits using the two capacitances and the two primary windings of high voltage transformer.

군산산단 주변의 주요 악취물질 규명 및 저감을 위한 기초조사

김성천,박성순,박태선,양고수 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2003 工學硏究 Vol.34 No.-

We examined odor concentration during two seasons(fall and winter). The results were as follows : We confirmed the concentration of H₂S, MM, DMS were high. And especially DMA, TMA and i-PA were detected highly in fall and odor indices of those were more than 1, so we confirmed those materials were odor origin materials, but did not detected those materials in winter. The concentrations of n-butylicacid and MEK in VOCs in winter were higher than fall. Therefore we think that examination odor materials with temperature are very important. The concentrations of DEA, i-BA and methanol, methyl ethyl ketone(MEK), methyl cyclo hexane, toluene, and stylene were not exceed minimum sensitive concentration, but those are presumed odor potential material. The odor origin materials in Kunsan industrial complex in fall were H₂S, DMA, TMA, i-PA, n-butylicacid, and the odor potential material were MMA, sec-BA, methyl ethyl ketone(MEK). The odor origin materials in Kunsan industrial complex in winter were H₂S, MM, DMS, n-butylicacid, and the odor potential material were DEA, i-BA, methyl ethyl ketone(MEK), methyl cyclohexane. The dilute magnification in Kunsan industrial complex in fall were examined DMA 10, TMA 3 and total of those was 13, and that in winter were examined H₂S 3, MM 2, DMS 2 and total of those was 8. But the regulation of boundary of factory in industrial complex is <20. The number of odor intensity(1.0 - 2.0) were that H₂S was one in fall and four in winter and therefore that of total five. And the number of odor intensity(1.0 - 2.0) of TMA was four in fall. Generally a civil appeal occur that odor intensity is more than 2.0.

전주산업단지 및 주변지역 VOCs 및 악취물질 모니터링(Ⅱ)

박성순,김용문,박비오,양고수 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2003 工學硏究 Vol.34 No.-

Important main odorous componds and VOCs(volatile organic componds) possibly emitted from the Jeon-Ju Industrial Sites were identified and measured in amount through making air sampling over Jeon-Ju Industrial Sites and analyzing them with the sate of the art analytical instrument. Sampling sites were chosen 8 points by considering the industrial characteristics for the 1,2 Industrial Sites and 2 points for the 3 Industrial. Site Sampling times were two times, the first was September. 2002, the second was November. 2002, and the third February. 2003. Canister sampling units and polyester bags were used to collect 6 liters air samples during 1hour or 3 minutes for VOCs and polyester bags were used to sample 10∼50 liters of air for 3 minutes depending on analytic characteristics of odor compounds. The important main VOCs were measured as ahexane(11.7ppb), 2-methyl(10.3ppb), methyl acetate(9.3ppb), methyl cyclopentane(7.2ppb), dichloromethane(5.2ppb), toluene(4.9ppb), m,p-xylene(4.8ppb), methanol(4.7ppb), M.E.K(methyl ethyl ketone : 3.9ppb), ethyl benzene(3.6ppb), n-undecane(3.6ppb), o-xylene(2.6ppb), 2-methyl hexane(2.6ppb), n-butylacetate(2.4ppb) as in oder of average concentration for the Industrial Sites. In the case of measurement ingredient for sulfur compounds, appeared by MM (N.d - 1.67ppb), DMS(N.d - 1.32ppb), DMDS(N.d - 1.76ppb). NH_(3) was measured as below the detection limit of the instrument. Among aldehydes, form aldehyde, acetaldehyde were detected very highly as 0.1- 1ppm over all the Industrial Sites.

PC 상에서 On-line 한글 인식에 관한 연구

이재도,양승복,정수웅 대구보건대학 1994 대구보건대학 論文集 Vol.14 No.-

In this paper, Using a Fuzzy theory an On-Line phoneme recognition procedure of Korean characters is studied. The recognition method is performed by reading the pixel coordinates, finding the feature points, recognizing the stroke, recognizing the phoneme in order. In the course of recognizing the stroke, first the feature points of an inputed stroke is characterized by starting point, end point, and bending point. and then, based on 0, 5, 6, 7, 8, 9, and 10 stroke code among the recognized stroke the distance or direction between base stroke and the next input stroke is used for recognizing the phoneme

Paraquat 투여 백서에서 Cyclophosphamide와 Dexamethasone의 치료 효과

신정철,신양수,유병전,임현성,정태흥,박찬국,오금탁,이병래 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.16 No.1

Paraquat (N,N'-dimethy 1-4,4'bipyrydinium : Gramoxone^(R), a widely used herbicide, is extremely toxic to all green plants and many eukaryotic organisms. In human, paraquat intoxication leads to multiple organ failure, it preferentially damages the lung, kidney and liver and may result in death. The participation of superoxide in initiating tissue damage by administration of paraquat is well known in which one electron reduction of paraquat leads to the formation of radical species which react with molecular oxygen to give superoxide. This process initiates immunological changes with the activation of neutrophilic leukocytes, which is related to further production of superoxide. In this experiment, therapeutic effects of cyclophosphamide and dexamethasone on blood cell count, malondialdehyde as a indicator of lipid peroxidation, and antioxidant enzymes levels in the lung, liver and kidney of paraquat intoxicated rats were inbestigated. The WBC count were significantly decreased by combined treatment of cyclophosphamide and dexamethasone in paraquat intoxicated rats at 3 and 5 days but RBC count were not changed. The contents of malondialdehyde were significantly decreased in the lung and Kidney by combined treatment at 10 days after paraquat intoxication. The catalase acitvities were markedly increased in the lung and liver of rats at 10 days after paraquat intoxication, and superoxide dismutase activities showed minimal changes in the lung, liver and kidney of rats by combined treatment. These results suggest that paraquat induced tissue damage in rats can be redeced by combined administration of cyclophosphamide and dexamethasone.

전주,익산지역 산업단지 악취 및 유해대기오염물질 발생원 조사

권영호,박성순,양고수 전북대학교 공학연구원 ( 구 전북대학교 공업기술연구소 ) 2002 工學硏究 Vol.33 No.-

VOCs (Volatile Organic Compounds) have been produced commercially and used for many purposes in the chemical industry including the manufacture of herbicides, plastics, and solvent. Their emissions affect the change of climate, the growth and decay of plants, and the health of human beings and animals. Therefore it is necessary to limit and control of VOC emission. There are various removal technologies of VOCs, such as catalystic oxidation, biofiltration, Adsorption, Thermal oxidation and Menbrane separation. In this study, we examined both source and components of odor and VOC pollutants emitted from Jeonju and Iksan industrial Area. According to the results, the main VOCs used in the two industrial Area were benzene, toluene, chloroform, methanol, methylene chloride, xylene, ethyl ethyl ketone etc. Especially, hydrogen peroxide and methanol were extremely used in these complex. The regulation of VOC will be more strict within near future. Therefore, this research work will be applicable removal efficiency of VOC emitted from Jeonju and Iksan industrial Area as a fundamental data.

임상검체에서 분리된 그람 음성 세균들에 대한 Isepamicin의 시험관내 항균력

권현희,박수진,소민욱,박현구,최성호,김미나,최상호,정진용,우준희,김양수 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background : The increasing incidence of multidrug-resistant gram-negative bacteria causing nosocomial infections is an important clinical problem. Isepamicin is a recently developed aminoglycoside which has been known to have potent activity against gram-negative organisms. We evaluated the in vitro activities of isepamicin and other aminoglycosides against a large number of gram-negative organisms. Materials and Methods : We tested the in vitro antimicrobial activities of isepamicin, amikacin, gentamicin, and tobramycin against 566 gram-negative organisms collected between January 2006 and June 2006 in Asan Medical Center. Minimal inhibitory concentrations (MICs) were determined and interpreted according to the recommendations of Clinical and Laboratory Standard Institute (CLSI). The breakpoint MIC used for interpretation of isepamicin was MIC≤16 ㎍/mL as susceptible, 32 ㎍/mL as intermediate, and 64 ㎍/mL as resistant. Results : The MIC_(50)/MIC_(90) of isepamicln for Escherichia coli, Klebsiella pneumon/ae, Pseudomonas aeruginosa, Acinetobacter baumannii, and Enterobacter cloacae were 1/2, 0.5/>128, 4/16, 16/>128, and 1/2 ㎍/mL, respectively. The susceptibilities for E. coli, K. pneumoniae, P. aeruginosa, A. baumannii, and E. cloacae were 100%, 86.4%, 89.7%, 50.0%, and 96.6%, respectively. For E. coli, K. pneumoniae, P. aeruginosa, and E. cloacae, isepamicln had better in vitro activities than gentamicin and tobromycin, and had similar activities with amlkacin. For A. baumanii, all four tested aminoglycosides had similar in vitro activities. Conclusion : Isepamicin had excellent in vitro activities against gram-negative organisms, except A. baumanii. The overall in vitro activities were similar with amikacin. 목적 : 그람 음성 세균은 다양한 지역사회 및 병원 획득 감염의 원인균이다. 최근에는 병원 감염을 일으키는 그람 음성 세균에서 항균제 내성균의 출현과 확산이 큰 문제가 되고 있다. Isepamicin은 최근에 소개된 gentamicin B의 유도체로 외국에서의 연구에 의하면 그람 음성 세균들에 대한 항균력이 우수함이 보고 된 바 있다. 본 연구에서는 우리나라의 임상 균주들을 대상으로 그람 음성세균에서 isepamicin의 시험관내 항균력을 기존의 아미노배당체 제재들과 비교하여 평가하고자 하였다. 재료 및 방법 : 2006년 1월에서 6월 사이에 서울아산병원 환자에서 분리된 Escherichia coli 113 균주, Klebsiella pneumoniae 110 균주, Pseudomonas aeruginosa 117 균주, Acinetobacter baumannii 108 균주, 그리고 Enterobacter cloacae 118 균주를 대상으로 isepaimcin, amikacin, gentamicin, tobramycin에 대한 최소억제농도(minimal inhibitory concentration, MIC)를 한천 희석법(Mueller-Hinton Agar)을 이용하여 측정하였다. 감수성여부는 CLSI 기준에 따랐으며, isepamicin은 MIC≤16㎍/mL를 감수성, MIC=32 ㎍/mL를 중등도 내성, MIC≥64 ㎍/mL를 내성으로 판정하였다. 결과 : Isepamicm의 E. coli, K. pneumoniae, P. aeruginosa, A baumannii, E. cloacae에 대한 MIC_(50)/MIC_(90)은 각각 1/2, 0.5/>128, 4/16, 16/>128, 1/2 ㎍/mL였고, 항균제 감수성률은 차례대로 100%, 86.4%, 89.7%, 50.0%, 96.6%였다. 기존 아미노배당체 제재들과 비교하면 E. coli, K. pneumoniae, P. aeruginosa, E. cloacae에서는 amikacin과 비슷한 감수성률을 보였고, gentamicin과 tobramycin보다 높은 감수성률을 보였다. A baumannii의 경우 isepamicin의 감수성률이 50.0%로 비교적 낮았지만 amikacin, gentamicin, tobramycin도 각각 50.0%, 46.3%, 47.2%의 감수성률을 나타내어 4가지 항균제가 모두 비슷한 항균력을 보였다. 결론 : Isepamicin은 그람 음성 세균들에 있어 기존의 아미노배당체 제재들과 비교했을 때 amikacin과는 동등한 시험관내 항균력을 보이고 gentamicin, tobramycin보다 뛰어난 시험관내 항균력을 보여 사용이 유망한 아미노배당체 중 하나라 생각된다.

혈액암환자에서 조혈모세포 이식 후 따르는 헤르페스 바이러스 감영 양상

이호섭,탁희상,신성훈,김양수,남성진,김혜수,박진희,정수현,김성빈,김예나 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.1

배경 : 헤르페스바이러스과에는 단순포진 바이러스(HERPES SIMPLEX VIRUS, HSV), 수두대상포진 바이러스 (VARICELLA-ZOSTER VIRUS, VZV), 엡스타인-바 바이러스 (EPSTEIN-BARR VIRUS, EBV), 그리고 거대세포 바이러스 (CYTOMEGALOVIRUS, CMV) 등이 있다. 헤르페스바이러스 감염은 혈액암환자에서 조혈모세포 이식 환자에서 전파 (dissemination), 이차감염, 세균 중복 감염의 심각한 합병증을 일으킬 수 있다. 하지만 항암약물치료를 받는 림파종 환자에서 항 바이러스 약제의 사용 용량과 기간에 대한 concensus는 없다. 헤르페스바이러스 감염에 대한 발생율과 위험인자를 후향성으로 분석하였다. 방법 : 고신대학교 복음 병원에서 1995년 6월부터 2009 년 2월 사이에 새롭게 진단되어 조혈모세포 이식을 받은 전체 58명의 환자들이 후향적으로 현 연구에 등록했다. 헤르페스 바이러스 감염은 임상적 진단, 혈청학적 검사 또는 병리학적 진단에 기초하여 확진한다. 환자들의 특성은 다음과 같다: 평균 연령은 44세 (범위 19-62세)였고 남녀비는 30:28이었다. 등록된 질환은 백혈병 (n=9, 15.5%), 림프종 (n=30, 51.7%), 다발성 골수종 (n=12, 20.7%), 재생불량성 빈혈 (n=6, 10.3%) 그리고 골수이형성증후군 (n=1, 1.7%)이 포함되었다. 결과는 chi-squre test나 independent samples T test를 사용하여 분석되었다. Multivariate analysises에 대해 logistic regression test를 사용하였다. 결과 : 15명의 환자들 (25.9%)에서 조혈모세포 이식후 헤르페스 바이러스 감염이 발생하였다. 조혈모세포 이식 5년간 누적 발생율은 53.9%였다. Univariate analyses에서 헤르페스 바이러스 감염에 대한 유의한 위험 인자는 없었다. 하지만 조혈모세포 이식후 생존 기간(40.18 ± 30.14 months vs 20.06 ± 26.67 months, p=0.018)은 헤르페스 바이러스 감염의 낮은 발병율과 유의한 관련성이 있었다. 이식 편대 숙주질환 (GVHD)의 존재 (37.5% in developed GVHD vs 0% in no GVHD, p=0.200), 동종조혈 모세포 이식에서 면역억제요법의 기간 (15.98 ± 14.02 months vs 6.78 ± 3.67 months, p = 0.374)은 헤르페스 바이러스 감염에 대한 위험인자가 아니었다. 결론 : 조혈모세포 이식 후 생존 기간은 어사이클로비어 예방을 받은 혈액암 환자에서 헤르페스 바이러스 감염의 낮은 발병율과 연관성이 있는 것으로 보인다. 저용량의 어사이클로비어 예방은 헤르페스 바이러스 감염의 고위험군인 조혈모세포 이식을 받은 혈액암 환자에 필요하리라 생각된다. Background : Herpesviridae family includes herpes simplex virus, varicella zoster virus, Epstein-Barr virus, and cytomegalovirus, etc. Herpesviridae viral infection (HVI) can lead to serious complications including dissemination, secondary infection, bacterial superinfection in patients with hematologic malignancy following hematopoietic stem cell transplantation (HSCT). But there was no consensus on the dose and duration of antiviral agents prophylaxis in patients undergoing chemotherapy. We retrospectively analyzed the incidence and the risk factors for HVI. Method : A total of 58 patients who newly diagnosed and received HSCT with prophylaxis of acyclovir at the Kosin University Gospel Hospital, Busan, Korea between June 1995 and February 2009 were enrolled retrospectively in the current study. HVI was confirmed based on clinical diagnosis, serologic test or pathologic diagnosis. The characteristics of the patients were as follows: the median age was 44 years (range 19-62 years) with a female-to-male ratio of 30:28. The enrolled diseases included leukemia (n=9, 15.5%), lymphoma (n=30, 51.7%), multiple myeloma (n=12, 20.7%), aplastic anemia (n=6, 10.3%) and myelodysplastic syndrome (n=1, 1.7%). The results were analyzed using a chi-square test and independent samples T test. For the multivariate analysis, we used logistic regression test. Results : Fifteen patients (25.9%) developed HVI after HSCT. The cumulative incidence of HVI was 53.8% at 5 years after HSCT. In univariate analysis, there was no significant risk factor for HVI. The presence of graft-versus-host disease (GVHD) (37.5% in developed GVHD vs. 0% in no GVHD, p=0.200), duration of immunosuppressive therapy (IST) in allo-SCT (15.98 ± 14.02 months vs. 6.78 ± 3.67 months, p = 0.374) were not risk factors for HVI. Conclusion : The incidence of HVI was similar to that in historical other studies. There was no risk factor associated with development of HVI. Most of the HVI occurred within the first 24 months after transplantation. So long term use of antiviral prophylaxis may be needed to prevention of HVI after HSCT.

CRM 아스팔트의 친환경적 특성

유병로,박성의,한양수 大田産業大學校 2000 한밭대학교 논문집 Vol.17 No.1

Improvement of environmental friendly characteristics on asphalt pavement is one of the important processes to make good quality asphalt. The asphalt mixture with CRM (Crumb Rubber Modifier) is known to show a better performance in penetration, noise reduction, physical characteristics including resisting thermal cracking, fatigue cracking and rutting compared with the conventional mixture. In this study, the test on the environmental friendly characteristics, physical and mechanical characteristics of the domestic crumb rubber modified asphalt and conventional asphalt(AP-5) were conducted. The test results show that CRM asphalt has better physical and mechanical characteristics including indirect tensile strength and stiffness modules than that of conventional asphalt. The results from the test of environmental characteristics can be summarized by the followings. The optimum asphalt content of CRM mixture by Marshall test showed the range from 5% to 5.8%. The penetration ability of CRM asphalt has about a hundred times higher than conventional asphalt. CRM asphalt was considered to improve the environmental characteristics on asphalt pavement.

이종재 브레이징 계면에서의 균열거동 해석

오환섭,김시현,김성재,양인수 한국공작기계학회 2002 한국생산제조학회지 Vol.11 No.6

Applications of brazing in the studying fields such as high-speed machining are very increasing in various industry fields. Therefore, applying to the fracture mechanics by numerical analysis method is very important to analyse the crack problem dissimilar materials in brazed interface. In this study, stress intensity factor(SIF) is analysed to investigate crack behavior on the crack tip of dissimilar materials in brazed interface such as a hardmetal and a HSS by two dimensional(2-D) BEM. Kelvin's solution was used as a fundamental solution in BEM analysis and stress extrapolation method was used to determine SIF.