Anti-Inflammatory Effect of By-Products from<i>Haliotis discus hannai</i>in RAW 264.7 Cells

Rho, Ho-Seok,Kim, Hyang,Kim, Jung-Ae,Karadeniz, Fatih,Ahn, Byul-Nim,Nam, Ki-Ho,Seo, Youngwan,Kong, Chang-Suk Hindawi Limited 2015 Journal of chemistry Vol.2015 No.-

<P>Several reports promoted the potential of shellfish due to their ability to act as antioxidant, anti-inflammatory, and antimicrobial agents. Pacific abalone,<I>Haliotis discus hannai</I>viscera is, reported to possess bioactivities such as antioxidative stress and anti-inflammatory. In this study, anti-inflammatory potential of mucus-secreting glands from shell-shucking waste of<I>H. discus hannai</I>was evaluated using RAW 264.7 mouse macrophage cell model. Results indicated that presence of<I>H. discus hannai</I>mucosubstance by-products (AM) significantly lowered the nitric oxide (NO) production along the expressional suppression of inflammatory mediators such as cytokines TNF-<I>α</I>, IL-1<I>β</I>, and IL-6 and enzymes iNOS and COX-2. Also, AM was shown to increase expression of anti-inflammatory response mediator HO-1. Presence of AM also scavenged the free radicals<I>in vitro</I>. In conclusion, by-products of<I>H. discus hannai</I>are suggested to possess notable anti-inflammatory potential which promotes the possibility of utilization as functional food ingredient.</P>

Tabes Dorsalis의 핵자기공명영상 및 전기생리학적 소견

권기한,김성민,권석범,이병철,조광호,주정희 대한신경과학회 1999 대한신경과학회지 Vol.17 No.3

패밀리레스토랑 종업원의 위생과 청결에 관한 중요도 인식

고호석,김선경,김동기,김범진 한국조리과학회 2005 한국식품조리과학회지 Vol.21 No.2

The purpose of this study was to identify factors associated with sanitation and cleanliness regarding the importance of family restaurant employees in the Ulsan and Basin areas. Accordingly, this study conducted a survey questionnaire consisting of 28 measures of food-service as well as major subject descriptors. From the results, the frequency, descriptive, factor, correspondence analysis, major findings and marketing implications could be summarized as follows: First, 6 factors were extracted: cooking and control factor, food and tableware handling factor, personal cleanliness condition factor, purchase and receiving factor, unit food material store factor and Kitchen utensil sanitation factor. KMO and Bartlett'stest statistics showed that the data fitted the factor analysis well. Results of factor analysis, average variance extracted estimates and shared variance showed that the convergent and discriminant validity of 6 factors are supported and Cronhach's alpha showed that the internal consistency of the 6 factors was supported. Second, correspondence analysis indicated that statistically significant relationships existed between some of the family restaurant employee sanitation and cleanliness factors and the family restaurant enterprise.

Azithromycin으로 치료한 임신 중 쓰쓰가무시병 1예

김광석,최진욱,서호종,김기훈,박성호,서광섭,고성만,김순혜,김호정 대한감염학회 2001 감염 Vol.33 No.5

We report a case of tsutsugamushi disease in a 26 year-old pregnant woman who was treated with azithromycin. Her gestation period was 27 weeks and she admitted with fever, rash, and eschar on the right shoulder. Currently recommended medications for the treatment of scrub typhus are doxycycline or chloramphenicol. But, these drugs are class D drugs according to the U.S. Food and Drug Administration (FDA) Fetal Risk Summary, so they couldn't be used to treat pregnant women. Recently, a few case reports suggested that azithromycin, a relatively new macrolide antibiotic, was effective and safe for the treatment of scrub typhus in pregnant women. And, there is no evidence that azithromycin causes harmful effects to the developing fetus or to children. On the basis of current in vivo test that confirms the effectiveness of azithromycin, it may be the drug of choice for the treatment of scrub typhus in pregnant women and children. (Korean J Infect Dis 33:380-382, 2001)

소아 신장질환에 대한 임상 통계적 관찰 : 11년간의 고찰 An Eleven-Years Experience

이재호,정기영,유재홍,최동석 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.1

Statistical analysis of renal inpatients admitted to the department of pediatric ward of Chungnam National University Hospital from 1978 to 1988 was performed according to their annual incidence of each disease, disease pattern, and age distribution. Renal diseases were found in 628(6.16%) among 10,194 total inpatients from 1978 to 1988. Male to famale ratio of renal disease was 1.99 to 1. Annual incidence of acute glomerulonephritis was decreased but no significant change was noted in the incidence of nephrotic syndrome and urinary tract infection. Acute glomerulonephritis was the leading cause of admission in all age groups and it constituted 28.82% of total renal patients. It was followed by nephronic syndrome(23.24%), urinary tract infection(16.56%). Wilms’ tumor(7.64%), Henoch-Schonlein nephritis(6.21%), and recurrent hematuria(4.45%). Urinary tract infection showed relatively high incidence in infancy and acute glomerulonephritis and nephrotic syndrome were high in older age group. Renal diseases were most frequently found in 7-9 years old age group. Chronic renal failure and recurrent hematuria were relatively frequent in over 12 years old age group.

아데노이드 및 구개편도 절제술이 비저항과 비강 내 Geometry에 미치는 영향

나기상,박찬희,구본석,김영덕,김관호,박용호 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

수술 전 최소단면적이나 비강 부피는 아데노이드나 구개편도의 비대 정도와 상관관계를 보이지 않았으나 비저항은 아데노이드 비대 정도와 유의한 상관관계를 보였다. 구개편도 및 아데노이드 절제술 후 코막힘과 구호흡 증상의 유의한 호전을 보였다. 수술 후 비강의 최소단면적과 부피 등 nasal geometry는 통계적으로 유의한 변화가 없었으나 비저항은 수술 후 유의한 감소를 보였으며 수술 후 비저항의 감소 정도는 아데노이드 비대 정도와 유의한 상관 관계를 보였다 . 이상의 결과로 아데노이드와 구개편도의 비대를 보이는 소아에서 코막힘 증상을 일으키는 데는 아데노이드 비대가 주요 원인이 되며 주로 비강의 후방에 위치한 아데노이드의 mass effect에 의할 것으로 생각한다. The aim of this study was to determine whether adenoid or tonsillar hypertrophy and subsequent adenoidectomy and tonsillectomy affect pediatric nasal airway resistance and nasal geometry and to evaluate the relationships between the degree of hypertrophy and nasal airway resistance or nasal geometry. Thirty-two children, aged 3 to 15 years, selected for adenoidectomy and tonsillectomy due to chronic nasal obstruction and mouth breathing were enrolled. The size of adenoid was evaluated by cephalometric radiograph. The degree of tonsillar hypertrophy was graded clinically. Nasal airway resistance and nasal geometry was evaluated by active anterior rhinomanometry and acoustic rhinometry respectively. These measurements were repeated one month and three months post-operatively. The size of adenoid was found well correlated to preoperative nasal airway resistance. However, there were no correlations between the degree of tonsillar hypertrophy and preoperative nasal airway resistance or nasal geometry. Nasal geometry was not changed after operation. However, nasal airway resistance was reduced significantly at 3 months after operation and the size of adenoid was found well correlated to postoperative changes of nasal airway resistance.

출생순위와 정신장애

석재호,안석철,손봉기 大韓神經精神醫學會 1978 신경정신의학 Vol.17 No.2

There have been many reports which dealt with the matter of incidence of schizophrenia, controlled by family size and sibling order. They got no uniform result but many of them suggested a possible relation between the schizophrenic incidence and the sibling order. Meanwhile the family size is getting smaller. Anticipation of this leads us to deal with the problem of mental hygiene in the small sized family. So the authors have chosen the mental patients who have two siblings, in the O.P.D. and the ward of Department of Neuropsychiatry of Han-Gang Sacred Heart Hospital from September 1976 to November 1977 to see the incidence of psychoses and neuroses among three siblings. The authors could sample 124 cases of psychotic and neurotic patients excluding patients with brain syndromes and 60 cases of organic brain syndromes, the control group. The results were as follows: 1. Among 29 psychotics, 12 were the first born, 7 the second born and 10 the third born. Among 95 neurotics, 30 cases were the first born, 37 the second born and 28 the third born. No significant difference was noted among these features. 2. In the subgroups of one son and two daughters, 3 brothers, and 3 sisters, no siginificant relationship in incidnece of mental disorder could be found. 3. In the subgroups of two sons and one daughter, the incidence of neurosis was significantly high in females. 4. In the group of organic brain syndromes, there was no significant difference in the incidence of psychosis and neurosis among different sibling orders.

한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고

양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1

The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.

크론병에 대한 CoPPLX의 방어효과에 대한 연구

이호학,김유림,문창기,이재일,양병윤,김종수,이정민,정재혁,안석진,박상준,김윤권,김소연,김영중,조민구,최영자,장성조 圓光大學校 醫科學硏究所 2005 圓光醫科學 Vol.20 No.1

水産專門大學 漁業科 敎育課程 開發硏究

裵錫悌,宋之浩,李吉來,鄭興基,洪聖根,趙鳳坤,朴種洙 군산대학교 1983 群山水産專門大學 硏究報告 Vol.17 No.1

In order to develop the curriculum of the fishery department in the fisheries Jr. college, We have collected and analyzed the domistic and foreign data adquated to the fishey department under the international trend, also we gathered the opinion from the inquiring paper investigation and consultation to the industrial field, concerned college and graduate during the 6 month from September 1982. The fishery department curriculum in fisheries Jr. college will be industrialized with the concerned technics and knowledge in relation to speciality of maritime affairs. Accordingly, we have developed the adquate curriculum which is practical and can be cultivated the technician to adopt in the industrial society.