Research Textbook of School Music Education in the Late Qing Dynasty and the Early Republic of China

( Tao Tingting ) 인문사회과학예술융합학회 2020 인문사회과학예술융합학회지 Vol.4 No.1

From the perspective of music education, this paper takes school music education in late Qing Dynasty and the early Republic of China as the research object, and tries to analyze textbooks of music education in schools of that time which is based on the literature and historical materials, hoping to provide material for further promoting the research of Chinese Music education in the 20th century.

Segmental Quantitative MR Imaging Analysis of Diurnal Variation of Water Content in the Lumbar Intervertebral Discs

Tingting Zhu,Tao Ai,Wei Zhang,Tao Li,Xiaoming Li 대한영상의학회 2015 Korean Journal of Radiology Vol.16 No.1

To investigate the changes in water content in the lumbar intervertebral discs by quantitative T2 MR imaging in the morning after bed rest and evening after a diurnal load. Twenty healthy volunteers were separately examined in the morning after bed rest and in the evening after finishing daily work. T2-mapping images were obtained and analyzed. An equally-sized rectangular region of interest (ROI) was manually placed in both, the anterior and the posterior annulus fibrosus (AF), in the outermost 20% of the disc. Three ROIs were placed in the space defined as the nucleus pulposus (NP). Repeated-measures analysis of variance and paired 2-tailed t tests were used for statistical analysis, with p < 0.05 as significantly different. T2 values significantly decreased from morning to evening, in the NP (anterior NP = -13.9 ms; central NP = -17.0 ms; posterior NP = -13.3 ms; all p < 0.001). Meanwhile T2 values significantly increased in the anterior AF (+2.9 ms; p = 0.025) and the posterior AF (+5.9 ms; p < 0.001). T2 values in the posterior AF showed the largest degree of variation among the 5 ROIs, but there was no statistical significance (p = 0.414). Discs with initially low T2 values in the center NP showed a smaller degree of variation in the anterior NP and in the central NP, than in discs with initially high T2 values in the center NP (10.0% vs. 16.1%, p = 0.037; 6.4% vs. 16.1%, p = 0.006, respectively). Segmental quantitative T2 MRI provides valuable insights into physiological aspects of normal discs.

Nitrogen and Oxygen Co-doped Porous Carbon Fabric for Efficient Removal of Formaldehyde

Tingting Chen,Xiaosai Hu,Tao Zhao,Yuanyu Ge 한국섬유공학회 2022 Fibers and polymers Vol.23 No.7

Formaldehyde can pose a huge threat to human health due to its’ carcinogenic effect. Carbon materials asadsorbents are widely applied to remove formaldehyde hazards. However, most carbon materials with disadvantages of thelimited number of surface functional groups and the lack of suitable pore structure suffer from low adsorption rate for theadsorptive removal of formaldehyde. To improve the adsorption capability, oxygen (O) and nitrogen (N) elements co-dopedporous viscose-based activated carbon fiber (N-O-ACF) was prepared via oxidation-hydrothermal treatment. First of all, theO atom can be introduced into ACF through chemical oxidation. Then, with the help of the O atom bridging effect, N atomscan be efficiently incorporated into ACF, and the content of the N element is as high as 7.13 wt.%. Thus, an improvedadsorption performance of N-O-ACF for formaldehyde removal was achieved with the support of the synergistic effect of Nand O elements. The adsorption capacity of N-O-ACF for removing formaldehyde increased up to 226 mg g-1, while only161.5 mg g-1 was obtained for original ACF. The excellent formaldehyde adsorption capacity indicates that N-O-ACF may bea promising adsorbent in the field of indoor air purification.

Enhanced carrier transport and visible light response in CA-β-CD/g-C3N4/Ag2O 2D/0D heterostructures functionalized with cyclodextrin for effective organic degradation

Xue Li,Tingting Liu,Fei Tian,Xiyang Tao,Zhansheng Wu 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.11

The high cost and low carrier separation efficiency of g-C3N4/Ag2O photocatalysts affect its application in the degradation of organic pollutants. In this study, the CA-βCD/g-C3N4/Ag2O 2D/0D heterojunction photocatalysts were successfully prepared to enhance the visible light response and inhibit the electron-hole recombination simultaneously during pollutant degradation. The 10:1:1 CA-βCD/g-C3N4/Ag2O showed the outstanding photochemical catalysis performance for the degradation of organic pollutants. The degradation efficiency of methyl orange, reactive black and norfloxacin was 2.53, 1.92 and 1.14 times than that of 1:1 g-C3N4/Ag2O. In addition, 10:1:1 CA-β-CD/g-C3N4/Ag2O also showed excellent photocatalytic stability. The free radical scavenging experiment and electron spin resonance proved that ·O − 2 was the chief active specie in the degradation process. The mechanism research results showed that the formation of heterojunction improved the utilization rate of sunlight and promoted the separation efficiency of photo-generated electrons and holes, which significantly advanced the photocatalytic activity of the composite catalyst. The preparation of CA-βCD/g-C3N4/Ag2O provided ideas for modification of photocatalyst by macromolecular organic matter.

Molecular cloning, characterization, and functional analysis of a gene encoding 3-hydroxy-3-methylglutaryl-coenzyme A synthase from Matricaria chamomilla

Feng Xu,Tingting Tao,Qiangwen Chen,Xiangxiang Meng,Jiaping Yan,Jie Chang 한국유전학회 2016 Genes & Genomics Vol.38 No.12

3-Hydroxy-3-methylglutaryl-CoA synthase (HMGS) catalyzes the condensation of acetyl-CoA and acetoacetyl- CoA to form 3-hydroxy-3-methylglutaryl-CoA as the first committed enzyme in the mevalonate (MVA) pathway. HMGS plays an important role in the biosynthesis of the sesquiterpene, which is the main constituent of essential oil in Matricaria chamomilla. In this paper, a HMGS gene designated as McHMGS (GenBank Accession No. KU529970) was successfully cloned from M. chamomilla. The full-length cDNA of McHMGS was 1495-bp and contained a 1374-bp open reading frame. It encoded a 458-amino-acid protein with a calculated molecular weight of about 50.7 kDa and isoelectric point of 5.69. Sequence comparison revealed that McHMGS showed extensive homology with HMGSs from other plant species. Phylogenetic tree analysis indicated that McHMGS is clustered with the HMGS of Asteraceae in the dicotyledoneae clade. Further functional complementation of McHMGS in hmgsdeficient mutant yeast strain YSC6274 demonstrated that cloned McHMGS cDNA encodes a functional HMGS and mediates the MVA biosynthesis in yeasts. The tissue expression pattern analysis revealed that McHMGS expression level is highest in the flowers and lowest in the stems. Quantitative real-time PCR analysis showed that the expression of McHMGS was induced by MeJA, and the expression level is highest 24 h after induction. The characterization and expression of McHMGS can help in further studying the role of McHMGS gene in the biosynthesis of sesquiterpene in M. chamomilla.

A rapid and sensitive molecularly imprinted electrochemiluminescence sensor for Azithromycin determination in biological samples

Hu, Liqin,Zhou, Tingting,Feng, Jingwen,Jin, Hua,Tao, Yun,Luo, Dan,Mei, Surong,Lee, Yong-Ill Elsevier 2018 Journal of Electroanalytical Chemistry Vol.813 No.-

<P><B>Abstract</B></P> <P>Azithromycin (AZM) is a widely used macrolide antibiotic to treat infections caused by bacteria. Considering the side-effect to human health, a rapid and selective electrochemiluminescence (ECL) sensor was fabricated on the basis of molecularly imprinted polymer (MIP) modified carbon paste electrode as a recognition element. We systematically optimized the factors influencing the processes on the extraction and determination for AZM, including the amount of MIP power and paraffin oil, extraction solution, extraction time and the pH of Ru(bpy)<SUB>3</SUB> <SUP>2+</SUP> solution. Under the optimal condition, the wide linear range was observed from 1.0 × 10<SUP>−10</SUP> to 4.0 × 10<SUP>−7</SUP> mol L<SUP>−1</SUP>, and the limit of detection (LOD) was low as 2.3 × 10<SUP>−11</SUP> mol L<SUP>−1</SUP> (S/N = 3). The spiked recoveries of AZM in urine and blood samples were from 98.4% to 113.5% with RSD changing from 3.7% to 13.2%, respectively. The results of AZM determination by this proposed sensor were in accordance with that of high-performance liquid chromatography–tandem mass spectrometry method. Thus, the developed MIP-based ECL sensor will have a great potential application in rapid and sensitive determination of trace AZM in complex biological samples.</P> <P><B>Highlights</B></P> <P> <UL> <LI> ECL sensor </LI> <LI> MIP modified CP electrode </LI> <LI> Trace AZM determined in biological samples </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Performance study of g-C3N4/carbon black/BiOBr@Ti3C2/MoS2 photocatalytic fuel cell for the synergistic degradation of different types of pollutants

Guo Huilin,Yu Tingting,Zhao Lei,Qian Jun,Yu Jiahe,Zhang Yu,Teng Yongyue,Zhu Chunshui,Yang Tao,Chen Wenbin,Gong Picheng,Jiang Cuishuang,Gao Changfei,Yang Bing,Yang Chenyu 한국탄소학회 2023 Carbon Letters Vol.33 No.3

In this study, a bipolar visible light responsive photocatalytic fuel cell (PFC) was constructed by loading a Z-scheme g-C3N4/carbon black/BiOBr and a Ti3C2/MoS2 Schottky heterojunction on the carbon brush to prepare the photoanode and photocathode, respectively. It greatly improved the electron transfer and achieved efficient degradation of organic pollutants such as antibiotics and dyes simultaneously in two chambers of the PFC system. The Z-scheme g-C3N4/carbon black/BiOBr formed by adding highly conductive carbon black to g-C3N4/BiOBr not only effectively separates the photogenerated carriers, but also simultaneously retains the high reduction of the conduction band of g-C3N4 and the high oxidation of the valence band of BiOBr, improving the photocatalytic performance. The exceptional performance of Ti3C2/MoS2 Schottky heterojunction originated from the superior electrical conductivity of Ti3C2 MXene, which facilitated the separation of photogenerated electron–hole pairs. Meanwhile, the synergistic effect of the two photoelectrodes further improved the photocatalytic performance of the PFC system, with degradation rates of 90.9% and 99.9% for 50 mg L−1 tetracycline hydrochloride (TCH) and 50 mg L−1 rhodamine-B (RhB), respectively, within 180 min. In addition, it was found that the PFC also exhibited excellent pollutant degradation rates under dark conditions (79.7%, TCH and 97.9%, RhB). This novel pollutant degradation system is expected to provide a new idea for efficient degradation of multiple pollutant simultaneously even in the dark.

Dynamic Recrystallization and Grain Refinement in Extruded AZ31 Rod During Hot Torsion Deformation at 150 °C

Hongbing Chen,Bo Song,Ning Guo,Tingting Liu,Tao Zhou,Jiejun He 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.1

The dynamic recrystallization mechanism and microstructure evolution in an extruded AZ31 rod during hot torsion deformationat 150 °C were investigated. It indicated that several dynamic recrystallization mechanisms were initiated during hottorsion deformation, including discontinuous DRX (DDRX), continuous DRX (CDRX) and twinning induced DRX (TDRX). With increasing strain, CDRX became the dominant DRX mechanism and contributed to a remarkable refinement of grains. A gradient distribution of dynamic recrystallization grains on the cross section of samples generated due to the gradientshear strain in twisted samples. Hot torsion can also arouse the c-axis of grains to rotate towards the extrusion direction. From low strain to high strain, the recrystallized grains exhibited a similar texture development with the deformed grains. The relevant mechanisms were revealed.

Comparative analysis of metazoan chromatin organization

Ho, Joshua W. K.,Jung, Youngsook L.,Liu, Tao,Alver, Burak H.,Lee, Soohyun,Ikegami, Kohta,Sohn, Kyung-Ah,Minoda, Aki,Tolstorukov, Michael Y.,Appert, Alex,Parker, Stephen C. J.,Gu, Tingting,Kundaje, Ans Nature Publishing Group, a division of Macmillan P 2014 Nature Vol.512 No.7515

Genome function is dynamically regulated in part by chromatin, which consists of the histones, non-histone proteins and RNA molecules that package DNA. Studies in Caenorhabditis elegans and Drosophila melanogaster have contributed substantially to our understanding of molecular mechanisms of genome function in humans, and have revealed conservation of chromatin components and mechanisms. Nevertheless, the three organisms have markedly different genome sizes, chromosome architecture and gene organization. On human and fly chromosomes, for example, pericentric heterochromatin flanks single centromeres, whereas worm chromosomes have dispersed heterochromatin-like regions enriched in the distal chromosomal ‘arms’, and centromeres distributed along their lengths. To systematically investigate chromatin organization and associated gene regulation across species, we generated and analysed a large collection of genome-wide chromatin data sets from cell lines and developmental stages in worm, fly and human. Here we present over 800 new data sets from our ENCODE and modENCODE consortia, bringing the total to over 1,400. Comparison of combinatorial patterns of histone modifications, nuclear lamina-associated domains, organization of large-scale topological domains, chromatin environment at promoters and enhancers, nucleosome positioning, and DNA replication patterns reveals many conserved features of chromatin organization among the three organisms. We also find notable differences in the composition and locations of repressive chromatin. These data sets and analyses provide a rich resource for comparative and species-specific investigations of chromatin composition, organization and function.

A Dual Functional Ti-Ga Alloy: Inhibiting Biofilm Formation and Osteoclastogenesis Differentiation via Disturbing Iron Metabolism

Fupeng Li,Kai Huang,Jinbing Wang,Kai Yuan,Yiqi Yang,Yihao Liu,Xianhao Zhou,Keyu Kong,Tao Yang,Jian He,Chunjie Liu,Haiyong Ao,Fengxiang Liu,Qian Liu,Tingting Tang,Shengbing Yang 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Background Although biomedical implants have been widely used in orthopedic treatments, two major clinical challenges remain to be solved, one is the bacterial infection resulting in biofilm formation, and the other is aseptic loosening during implantation due to over-activated osteoclastogenesis. These factors can cause many clinical issues and even lead to implant failure. Thus, it is necessary to endow implants with antibiofilm and aseptic looseningprevention properties, to facilitate the integration between implants and bone tissues for successful implantation. To achieve this goal, this study aimed to develop a biocompatible titanium alloy with antibiofilm and anti-aseptic loosening dual function by utilizing gallium (Ga) as a component. Methods A series of Ti-Ga alloys were prepared. We examined the Ga content, Ga distribution, hardness, tensile strength, biocompatibility, and anti-biofilm performance in vitro and in vivo. We also explored how Ga3+ ions inhibited the biofilm formation of Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) and osteoclast differentiation. Results The alloy exhibited outstanding antibiofilm properties against both S. aureus and E. coli in vitro and decent antibiofilm performance against S. aureus in vivo. The proteomics results demonstrated that Ga3+ ions could disturb the bacterial Fe metabolism of both S. aureus and E. coli, inhibiting bacterial biofilm formation. In addition, Ti-Ga alloys could inhibit receptor activator of nuclear factor-κB ligand (RANKL)-dependent osteoclast differentiation and function by targeting iron metabolism, then suppressing the activation of the NF-κB signaling pathway, thus, showing their potential to prevent aseptic loosening. Conclusion This study provides an advanced Ti-Ga alloy that can be used as a promising orthopedic implant raw material for various clinical scenarios. This work also revealed that iron metabolism is the common target of Ga3+ ions to inhibit biofilm formation and osteoclast differentiation.