Hepatic Cirrhosis Occurring in a Young Woodchuck(Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus(WHV)

Kyu-shik Jeong,정원일,Jae-yong Chung,Mi-young An,Chae-yong Jung,Gyoung-jae Lee,Jong-soo Kang,Byeong-cheol Kang,Young-heun Jee,Bruce H Williams,Young-oh Kwon,Da-hee Jeong 대한수의학회 2003 Journal of Veterinary Science Vol.4 No.2

Cirrhosis Occurring in a Young Woodchuck (Marmota monax) Due to Vertical Transmission of Woodchuck Hepatitis Virus (WHV)Da-hee Jeong, Won-il Jeong, Jae-yong Chung, Mi-young An, Chae-yong Jung, Gyoung-jae Lee1, Jong-soo Kang1, Byeong-cheol Kang2, Young-heun Jee3, Bruce H Williams4, Young-oh Kwon5 and Kyu-shik Jeong*College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Korea1Shinwon Scientific Co., LTD, Research Institute, Suwon, Korea2Clinical Research Institute, Seoul National University, Seoul 110-744, Korea3College of Veterinary Medicine, Jeju National University, Jeju 690-756, Korea

Increased 11β-hydroxysteroid dehydrogenase type 1 contributes to barrier dysfunction in aged skin

( Beom Jun Kim ),( Noo Ri Lee ),( Chung Hyeok Lee ),( Young Bin Lee ),( Solam Lee ),( Hyun Jee Hwang ),( Eunjung Kim ),( Eung Ho Choi ) 대한피부과학회 2019 대한피부과학회 학술발표대회집 Vol.71 No.2

Background: 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) converts inactive cortisone into cortisol, an active form, and is expressed by several tissues including the skin. Excessive active glucocorticoid (GC) deteriorates skin barrier function. Objectives: To find out if 11β-HSD1 affects on the barrier function in aged skin. Methods: We have performed human and in vivo studies. We measured cortisol in stratum corneum (SC) and oral epithelium of the elderly and young. Hairless mice were used for 11β-HSD1 immunohistochemistry staining of skin and measuring skin barrier function and serum cytokines. 11β-HSD1 knock-out (KO) mice and its wild-type were used for measuring lipid synthesis related enzyme. Results: Cortisol levels were elevated in SC and oral epithelium of the elderly rather than young. The 11β -HSD1 expression was increased in immunohistochemistry stain of aged mice skin. Aged mice showed decreased transepidermal water loss (TEWL) and SC hydration, and increased SC integrity than young. Serum inflammatory cytokines including interleukin-1α, -4, -10, -31 and tumor necrosis factor-α were increased in aged mice than young. The expressions of lipid synthesis related enzymes in epidermis were elevated in KO mice and topical 11β -HSD1 inhibitor applied mice. Conclusion: 11β-HSD1 expression is elevated in aged skin. It increases active GC and then deteriorates skin barrier function.

국가예방접종전산등록체계 개발을 위한 민간의료 기관 하부구조 및 환경 조사연구

이무식,김은영,이건세,이석구,홍지영,김건엽,김대경,신의철,이연경,기몽서,나백주,김영택 한국모자보건학회 2003 한국모자보건학회지 Vol.7 No.2

한국어 학습자의 의사소통 특징 연구 : 의사소통이 잘 이루어지지 않은 경우를 중심으로

이지영 국제한국어교육학회 2002 한국어 교육 Vol.13 No.2

Jee-Young Lee. 2002. An Study of Communication within Korean Language Learners' Conversation. Journal of Korean Language Education 13-2: 227∼246. The Korean language research and education have emphasized the improvement of communicative competence of Korean language learners in these days. So many researchers are interested in communication theory. How Korean language users make and interpret the conversation? How Korean language users use the communication constraints in their conversation? What is the difference between Korean language users and learners using the communication constraints? It will be meaningful to examine how Korean language learners recognize the communication constraints of Korea. There are many communication constraints that the ways we open and close conversations, our conversational turn-taking signals, how we repair messages to make them interpretable, how bracketing is done, and so forth. Also how we change the topics, what are Grice's maxims of Cooperation Principle. These constraints smooth social interaction and interact with the system constraints. For example, Korean language users use many kinds of politeness expressions when they open and close the conversation according to the relation between speaker and hearer. For this purpose, I will analyze the communication within Korean language learners' conversation and explain the causes of the error. The result of this analysis can be used as an effective teaching method for Korean language learners. (Seoul National University)

기관지 방선균증의 임상 1례

이은영,장태원,정만홍,옥철호,이규원,손창배,이지숙,신은경,서정아,백종현,김영옥 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Actinomycosis is a chronic suppurative infection, whitch infiltrates mucosa-associated tissues. Thoracic, pelvic and cervicofacial infections of actinomyces are not uncommon, but endobronchial actinomycosis is rarely reported. We report a case of a 29 year old man who presented with a recurrent pneumonia and chronic cough. Fiberoptic bronchoscopy revealed occlusion of the right. lower medio-basal segment bronchus with exophytic endobronchial mass. The diagnosis was confirmed histologically by demonstration of sulfur granules in the bronchoscopic biopsy of the mass. Intravenous administration of amoxacillin and clindamycin followed by oral amoxacillin and clindamycin therapy resulted in complete recovery.

Light-induced isomerization dynamics of a cyanine dye in the modulus-controlled regime

Jee, Ah-Young,Park, Seohyun,Lee, Minyung Royal Society of Chemistry 2011 Physical chemistry chemical physics Vol.13 No.33

<P>The <I>trans</I>–<I>cis</I> isomerization of an excited molecule converts light energy into mechanical motion, which interacts cooperatively with its surroundings. To understand such a photodynamic process in solids, we investigated the internal twisting motion of 1,1′-diethyl-2,2′-cyanine iodide (DCI) in a series of poly(alkyl methacrylate) (PAMA) polymers by measuring the Young's moduli of the polymers with atomic force microscopy nanoindentation and the fluorescence lifetimes of the dye with time-correlated single photon counting. We found that the isomerization rate constant obtained from the average lifetime correlated well with the mechanical property of the matrix. Our results show that the light-induced molecular motion lies in the modulus-controlled regime in which the polymer matrix not only provides a rigid environment for the dynamics of the molecules but also participates actively in the motion. The concept of elastic modulus may be applicable to molecular rotor dynamics in any synthetic polymer and, in principle, can be extended to biopolymers such as proteins or DNA.</P> <P>Graphic Abstract</P><P>Twisting motion of a photoexcited cyanine dye in poly(alkyl methacrylate) polymers correlated well with the Young's modulus of the medium. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c1cp20835g'> </P>

간세포암의 고주파 열치료 후 천자침 경로를 통한 전이 1례

조영완,박석주,진한영,김준영,이재익,강명주,박정하,윤정희,박성재,지삼룡,이연재,이상혁,설상영 인제대학교 2006 仁濟醫學 Vol.27 No.-

Radiofrequency ablation(RFA), as a form of minimally invasive therapy for hepatocellular carcinoma, has become an important treatment modality. Because of limitation of surgery, RFA has become standard therapy for hepatocellular carcinoma in some situations. But there are some complications of RFA such as bleeding, infection, hematoma, adjacent organ thermal damage including intestinal perforation, needle track seeding, and so on. There are few reports in the literature that systematically evaluate the incidence of needle tract seeding and its associated risk factors. And only 2 cases of needle tract seeding of hepatocellular carcinoma after RFA were reported in Korea. We report a case of needle tract seeding of hepatocellular carcinoma after RFA.

대학생의 스포츠 활동 참가유형에 따른 자아존중감 및 건강통제소재의 관계

박주영,김지연,이준우,백승옥 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.6

The purpose of this study was to analyze the relationships between self esteem and health locus of control in sports participation type of university students. The subjects of the study was selected by stratified cluster random sampling method from the sports participation located in Seoul ' Kyung-Ki area in universty students. Among them 400 students are contacted as sampies to be studied. 29 of them are not reviewed because of untimely response and doubted sincerity of their answers. The author used questions from Rosenberg's Self-Esteem Scale SES (10 Questions, 1965, translated, edited and standardized by Kim, gui-bong, Kim, young-soo, Kang, sung-gu, Park, joo-young, Kim, young-ho, 1999) and Wallston, Wallston and DeVellis Multidimentional health Locus of Control Scale (18 Questions, 1978) to analyze the sample with statistical calculations including descriptive statistics analysis, one-way ANOVA, multiple correlation analysis for the study. The study conclusions from this study summarized as follow: First, there were differences in university students sports participation type depending on their characteristics such as sex, height, and weight. Second, the sports participation type among university students has a significant difference on the self-esteem. Third, the sports participation type among universty students has a significant difference on the health locus of control(internal health locus of control). Forth, there is some relationships between mental-health and body-consciousness in sports participation type of university students.

한국여성소설과 자서전적 글쓰기에 관한 연구

박영혜(Park Young-Hye),이봉지(Lee Bong-Jee) 숙명여자대학교 아시아여성연구원 2001 아시아여성연구 Vol.40 No.-

Women's autobiography is a kind of autobiography. Therefore, it should comply with the rules of the autobiographical genre in general. The question remains, why should we examine the theory of Women's autobiography separately? The study of Women's autobiography. however, comprises more than that of a special sub-genre because by adding a gender element to the study of autobiography, it has the potential to question the general rules and practices of the autobiography genre. Women's autobiography is a kind of autobiography. Therefore. it should comply with the rules of autobiographical genre in general. Nevertheless. why should we examine the theory of Women's autobiography separately? The study of Women's autobiography. however. means more than that of a special sub-genre because by adding a gender element to the study of autobiography. it has a potential to correct general rules and practices of the autobiography genre. With the emergence of feminism, however, this attitude has come to be criticized. Feminist researchers pay more attention to the difference and the specificity of Women's writing than to the would-be universality which men assert. As feminism. which emphasizes specificities. is introduced into literature, literature has come to undergo fundamental changes. As a result, in this study, theories of Women s autobiography have been studied on two levels regarding some works written by Korean women writers who are known to be autobiographical. The analysis of these novels tends to question the general rules of autobiographical writing and at the same time to explore the specificities of Women's autobiography. Therefore, the two directions: the study of autobiography in general and the study of Women's autobiography related to self-representation and female identity have been handled in this study. Considering this theoretical basis, this study chose to deal with the following four women writers: Na Hae-Suk. Park Wan-Sec. Suh Young-Eun and Shin Kyung-Sook. Park Wan-Seo and Shin Kyung-Sook both wrote novels in which the narration is in the voice of the author herself. In fact, the author. the narrator and the hero or heroine are the same person. such as in The Mountain. Would It Be There? and Room in Isolation. The work of Park Wan-Seo is a sort of reminiscence about the past and a testimony of ones being. In the work of Shin Kyung-Sook, we find the author writing from the present point moving freely over the past and the present creating a shared memory where the true and the pretext are interacting with the gaze of the other. The works of Na Hae-Suk and Suh Young-Eun are narrated by a third person, thus holding some distance from the life of the author. However, the similarity of living experiences of the author as a subject to those of the protagonist reveals meaningful implications of the ontological situation of being a writer as a woman who might have taken this tertiary discourse as writing strategy. It would be more interesting when we come to analyse the intervention of imagination and fiction to the extent of which an autobiographical novel of a woman writer would have more value with its tertiary aspect. The work of Na Hae-Suk reflecting her own life has been written in the form of an essay or confession. The novel Kyung-Hee can be considered a biographical novel written in a tertiary discourse which served for the passage of enlightenment and confession producing a more delicate effect, and thus permitting, to some extent, a new concept of modern Women's writing. Her Woman. a novel by Suh Young-Eun, is particularly interesting with its tertiary point of view of the protagonist whose similarity with the author can only be sorted out by the reader through the dark nightmare.

수입각증후군에 의한 급성 복증 1례

정은욱,지삼룡,이영태,박지훈,김동기,제인수,채두근,박성재,박은택,이연재,이상혁,설상영,정정명 白中央醫療院 2005 仁濟醫學 Vol.26 No.1

Afferent loop syndrome is an uncommon complication of a gastrectomy and Billroth Ⅱ reconstruction. It may cause symtoms at any time from the first postoperative day to many years after the gastrectomy. Afferent loop syndrome is characterized by abdominal pain, vomiting and elevation of serum amylase. Thus, it is difficult to differentiate afferent loop syndrome from other cause of acute pancreatitis. However, the history of gastrectomy can be an important clue for diagnosing afferent loop syndrome. We experienced one case of chronic afferent loop syndrome with acute pancreatitis. After appropriate management, the abdominal pain disappeared and serum amylase level decreased. We report this case with a review of relevant literatures.