판막 질환에서의 심근 섬유화 : 심근 조직을 이용한 형태학적 연구 및 혈청 생화학적 지표의 분석

강수진,박덕우,송재관,박경민,송종민,강덕현,한기훈,송현,이재원,주석중,송명근,김정선 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

북한강 상류 천연자원의 종합관리 시스템 개발

송화선,김남호,김동욱,장재형,정영준,임길재 강원대학교 석재복합신소재제품연구센터 1998 석재연 논문집 Vol.3 No.-

강원도 춘천시를 중심으로하는 북한강 상류는 수도권에 청정 상수원류를 제공하는 생활의 핏줄이다. 또한 수도권 지역 건설에 필수적인 석재 자원의 주요 공급 지역으로 알려져 있다. 본 연구에서는 이 지역의 보존과 체계적 개발을 위한 지리정보처리 기술을 이용한 천연자원 종합관리 시스템을 개발하였다. 이 시스템은 자원관리를 위한 막강한 도구와 기능 예를 들면 정보수집, 편집, 처리, 모델링, 분석 및 가시화기능을 제공한다. 결과적으로 이 시스템은 지하자원 분석, 천연자원의 기획 및 개발, 자연보호 등 자원관리와 연계된 문제를 효율적으로 해결할 수 있는 능력을 제공하고 있다. The upper stream area of the north Han river, which is located around the Chunchon city of the Kangwon province, is out essential resources, which supply clear drinking water to the capital city of out conutry, Seoul. This area has also produced stone and aggregate resources required for building and road constructions in the capital area For preservation and planned-development of this area, in this study, we have developed an integrated management system for natural resources, based upon geological information technologies. This system includes powerful tools and functions for resource management such as information collection, edition, processing, modeling, analysis, and visualization. As a result, this system may give us capabilities to efficiently handle a variety of resource management issues such as the analysis of underground resources, the planning and development of natural resources, the protection of environment and their related projects.

저장용기 및 저장온도에 따른 김치의 품질변화

송주은,김명선,한재숙 동아시아식생활학회 1995 동아시아식생활학회지 Vol.5 No.2

맛있는 김치의 저장기간을 연장시키기 위하여 여러가지 저장용기와 저장온도를 달리하여 각 군마다 5포기씩의 김치를 담그고 각각에 The effects of storage containers and storage temperatures on Kimchi quality were investigated. The results were summarized as follows : 1. Pabix, poly ethylene-back+plastic container, tupper-ware were much better than crock, stainless steel, and plastic container in keeping Kimchi. However, there was no significant differences between containers in the sensory test for Kimchi. 2. Kimchi stored at 18±2℃ was the most delicious, which revealed pH 4.30, acidity 0.45-0.50%, and salt concentration 3.10wt% in the 4th days after storage whereas sensory score for Kimchi quality was very low in the 12th days after storage. 3. PH in Kimchi stored at 5℃ after fermentation at 18±2℃ was slowly decreased as compared to the Kimchi stored at 18±2℃ after fermentation. 4. PH and acidity showed no significant changes after 90 days storage when Kimchi was stored at -5℃ or -80℃ were compared to that of the Kimchi stored at 18±2℃, but texture score of Kimchi stored at -5℃ or -80℃ after fermentation at 18±2℃, but texture score of Kimchi stored at -5℃ or -80℃ were compared to that of the Kimchi stored at 18±2℃ after fermentation. 5. In the group of Kimchi stored at 10℃, immediately after pickling it took 48days until the best conditions which were pH 4.30 and acidity 0.45-0.50% were matched. 6. The most promising method in keeping good taste and good quality of Kimchi was to store Kimchi at 5℃ after 4days fermentation at 18±2℃. And, for long period preservation of Kimchi, it took would be effective to store at -80℃ after fermentation at 18±2℃.

열처리에 따른 Cd₁-xZnxS/In 박막의 광학적 및 전기적 특성 분석

송우창,이경호,심상흥,이상교,심재선,박종국 三陟大學校 2002 論文集 Vol.35 No.-

In this thesis, effects of the thickness of indium films and the annealing temperature on optical and electrical properties of chemically deposited CdZnS films for the efficiency of the Cd1-xZnxS/CdTesolar cells were investigated. To improve the electrical conductivity of Cd1-xZnxs films, thin indium films(10-4Onm thickness)were evaporated on the suface of Cd1-rZnxs films. Experimental parameters such as indium film thickness, Zn mole fraction, and the annealing temperature in terms of structural and electrical properties of Cd1-xZnxs films were investigated. The diffusion process was carried out by heating the sample in air at 150-550℃ for 20 minute As the indium film thickness is increased, the resistivity decreases and the lowest value(0.3 O -cm)is obtained for Cd1-xZnxs films annealed at 450℃ with 40nm of the thickness.

능이버섯 단백분해효소의 특성

송영선,이종호,조재선 인제대학교 기초과학연구소 2000 자연과학 Vol.4 No.-

능이버섯으로부터 추출한 육류단백질 분해효소의 특성을 알아보기 위하여 능이버섯 조효소액을 제조하고 능이단백분해효소의 활성 측정조건을 결정하고, 우육과 우육단백획분의 분해에 미치는 영향을 전기영동법과 분광광도법으로 조사하였다. 능이버섯 단백분해효소는 pH 7.5, 73∼78℃에서 최적활성을 보였으며 50℃이상의 온도에서 변성하는 경향을 나타내었다. 능이버섯 단백분해효소는 키위,배에 비해 건조 중량 당 단백분해능이 각각 66배, 990배 높았으며, SDS-PAGE에 의한 우육단백에 대한 분해 특성 역시 능이버섯에서 우수하였다. 우육단백의 수용성, 불용성, 염용성 획분에 대한 능이버섯(100unit 첨가)의 가수분해 능력은 papain, bromelain, collagenase, bovine protease보다 월등히 높게 나타났다. This study was conducted to investigate the proteolytic properties of Sarcodon aspratus on meat proteins. The analytical condition for the measurement of enzyme activity was determined and the effect of Sarcodon aspratus on beef protein and its fractions were determined by SDS-PAGE and spectrophotometric method, respectively. Optimum temperature and pH of Sarcodon aspratus was 73-78℃, pH 7.5, respectively. However, the enzyme tended to be denatured at 50℃ for 10 min incubation. Proteolytic activity of Sarcodon aspratus was higher than those of kiwi and pear by 66 and 990 times by dry weight, respectively. It was appeared that proteolytic activity of Sarcodon aspratus toward beef protein by SDS-PAGE was prominent when compared to those of kiwi and bromelain. Furthermore, Sarcodon aspratus showed highest proteolytic activity toward all the beef protein fractions, which was followed by collagenase and bovine protease.

지역사회획득 폐렴의 치료지침 권고안

송재훈,정기석,강문원,김도진,배현주,서지영,심태선,안중현,안철민,우준희,이남용,이동건,이미숙,이상무,이영선,이혁민,정두련,지역사회획득 폐렴 치료지침 제정위원회 대한감염학회 2009 감염과 화학요법 Vol.41 No.3

A successful therapy of community-acquired pneumonia requires appropriate empirical antimicrobial therapy. Etiology and antimicrobial susceptibility of major pathogens of pneumonia can differ by country. Therefore, an ideal treatment guideline of community-acquired pneumonia should be based on the studies performed in each country. We developed a treatment guideline for community-acquired pneumonia in immunocompetent adults in Korea. This guideline was developed by the joint committee of the Korean Society for Chemotherapy, the Korean Society of Infectious Diseases, and the Korean Academy of Tuberculosis and Respiratory diseases.

補中益氣湯 투여가 장거리 달리기 선수의 에너지 및 전해질 대사에 미치는 영향 : changes in the energy and electrolyte metabolism among long distance runners

송순기,금동호,오재근,이명종 동국대학교 한의학연구소 1998 東國韓醫學硏究所論文集 Vol.7 No.1

스포츠 과학 분야에서는 운동 선수들의 경기력 향상과 운동 피로의 신속한 회복을 도모하기 위하여 한약을 복용하고 그 효과와 유의성에 대하여 연구가 활발히 이루어지고 있다. 격심한 운동을 수행할 때 나타나는 Glucose 등 에너지원의 고갈, Lactate 등 대사 산물의 축적, 전해질의 불균형 등의 여러 제반 증상이 氣虛로 인하여 나타나는 전신의 증후와 유사하다고 생각하여 補中益氣湯을 투여한 후 인체의 대사 변화를 관찰함으로서 운동수행능력에 미치는 영향과 유의성을 평가하고자 하였다. 본 연구는 장거리 달리기 선수를 대상으로 2주간의 補中益氣湯의 투여가 에너지 대사 및 전해질대사에 미치는 영향을 규명하기 위하여 최대심박수의 70% 강도의 운동을 실시한 후 운동전 안정시, 운동 직후, 휴식 후 10분, 휴식 후 30분, 휴식 후 1시간으로 나누어 혈액검사를 하였을 때 나타나는 각종 변인의 반응 양상을 비교 분석하여 유의한 결과를 얻었다. 혈중 에너지 대사에서는 free fatty acid와 Lactate 반응에서 유의성 있는 차이가 나타났고, 전해질대사에서도 Na^(+), Cl-와 K^(+) 반응에서 모누 유의성 있는 차이를 나타냈다. 그러므로 補中益氣湯은 에너지 및 전해질 대사에서 유의성있는 변화를 나타내었으며 운동수행능력의 향상에 유효하였다. Objective This experimental study was designed to investigate effects of Bo-joong-ik-gi-tang administration among long distance runners on changes of the energy and electrolyte metabolism. Materials and Methods All subjects were divided randomly with two groups, Bo-joong-ik-gi-tang Group (N=4) and control group (N=4) and performed to run the 400m track with 70% of HR max about 1 hour. The blood samples were collected from antecubital vein by 5㎖ syringes at before exercise, immediateIy after exercise, recovering- 10 min, recovering-30 min, recovering-1 hour. These sampie were used to analyze for the factors of the changes on metabolic responses. Firest, the primary factors on the changes of the energy metabolism were checked ; Glucose, Free fatty acid, Lactate, LDH. Second, the primary factors on the changes of the electroIyte metabolisrn were checked ; Na^(+), Cl^(-), K^(+). Results 1. The change of the energy metabolism 1) Glucose response was not shown significant difference between two groups. 2) Free fatty acid response in Bo-joong-ik-gi-tang group was significantly increased at recover-10 min. 3) Lactate response in Bo-joong-ik-gi-tang group was significantly decreased at immediately after exercise, recover-10 min, recover-30 min. 4) LDH response was not shown significant difference between two groups. 2. The change of the electrolyte metabolism 1) Na^(+) response in Bo-joong-ik-gi-tang group was shown significant difference between two groups at before exercise. 2) C^(-) response in Bo-joong-ik-gi-tang group was significantly increased at before exercise, immediately after exercise. 3) K^(+) response in Bo-joong-ik-gi-tang group was significantly increased at recover-10 min. Conclusion According to the above results, it was shown that Bo-joong-ik-gi-tang had the positive effects on changes of the energy and electrolyte metabolism for the long distance runners.

복강경을 이용한 대장 부분 절제 시행 1예

박재갑,서경석,정회원,김선회,오용석,송인성,박용현 대한대장항문학회 1993 Annals of Coloproctolgy Vol.9 No.1

낭성법랑모세포종, 함치성낭, 치성각화낭의 방사선소견과 Ki-67, PCNA, Cytokeratin 발현과의 연관성에 관한 연구

송만용,이삼선,이진구,이원진,허민석,이재일,민병무,최순철 대한구강악안면방사선학회 2004 Imaging Science in Dentistry Vol.34 No.2

Purpose : To compare the proliferation potential of the epithelial cells between unicystic ameloblastoma (UA), dentigerous cyst (DC), and odontogenic keratocyst (OKC) and to correlate this proliferation potential with the radiographic features of these three pathoses. Materials and Methods : Immunohistochemical expression of PCNA, Ki-67, and cytokeratin as a proliferation marker were assessed for 15 cases of UA, 15 cases of DC, and 15 cases of OKC. The degree of immunochemical expression of three proliferation markers were correlated with the radiographic features, especially cortical expansion (negative and positive) and shape of border (scalloped and round). Results : Using PCNA and Ki-67, OKC showed the highest proliferation potential and UA the lowest. Statistically significant differences were found between the OKC and the UA (p.0.05). However, no statistically significant difference was present according to the radiographic features in all pathoses. Using cytokeratin, there was no significant differences of proliferation potential among three pathoses. Conclusions : OKC epithelium has the most intense proliferation potential, followed by the dentigeous cyst and then unicystic ameloblastoma. There is no significant relation between the radiographic features and the proliferation potential of epithelium of these three pathoses.

專門大學 臨床病理과 敎育 年限에 關한 硏究

黃善哲,李昌珪,宋在雍 대한임상병리사협회 2001 대한임상병리사회지 Vol.21 No.1