Helicobacter pylori 감염진단을 위한 Asan Helicobacter 검사의 평가

이종욱,김범수,이경원,이재학,이재경,이창훈 대한임상미샐물학회 2003 Annals of clinical microbiology Vol.6 No.2

심혈관계 질환으로 관상질환 집중치료실에 입원한 환자들의 혜후 측정을 위한 APACHEⅢ점수 체계의 임상적 유용성

이공섭,이창선,최현주,홍종서,강지향,김도형,이민영,오인균,김병엽,김상억,김학찬,한승혜,이재용,지영우,안경주 대한순환기학회 2000 Korean Circulation Journal Vol.30 No.8

건축공사시방서에서의 KS규격의 국제인증방안에 관한 연구

김경식,이재섭,김용수,이규진,조용훈,최완철,전재열,이현수,구재동,이기환 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

The purpose of this research is make out construction specifications for International Construction. Using off-shore products incur cost increase and longer delivery term of construction. and inconvenient on International Construction. Expand the range of additional local products conforming to performance. Life Cycle Cost. maintainability. operability. user's acceptability, etc.. And this study is suggest the standard formats and the techniques for construction specification.

대아지 숭상을 위한 수문학적 가능성 평가

노재경,이재남 충남대학교 농업과학연구소 2008 농업과학연구 Vol.35 No.2

만경강 수계의 봉동 지점에서 자연사회환경개선의 하천유지유량을 확보하기 위해 상류에위치한 대아저수지를 높이는 방안에 대한 수문학적 타당성을 검토한 결과 다음과 같이 요약된다. 첫째, 동상-대아 직렬 연계에 의해 대아저수지로부터의 용수공급을 분석한 결과 용수공급량/유역면적은 1207.4 mm, 단위유역 용수공급량/강우량 비율은 95.8%, 용수공급량/유입량 비율은 153.1%, 용수공급량/저수량 비율은 236.1%, 유입량/저수량 비율은 200.6%였다. 둘째, 대아-경천 병렬 연계를 고려한 봉동 지점의 유량을 분석한 결과 유황은 연평균하여 풍수량 28.95 ㎥/s, 평수량 2.00 ㎥/s, 저수량 0.95 ㎥/s, 각수량 0.82 ㎥/s로 분석되었으며, 고시유량 1.32 ㎥/s보다 0.50 ㎥/s 적게 나타났다. 셋째, 대아저수지를 lOm 높인 경우 대아저수지로부터의 용수공급을 분석한 결과 용수공급량/유역면적은 1220.7 mm, 단위유역 용수공급량/강우량 비율은 96.8%, 용수공급량/유입량 비율은 154.6%, 용수공급량/저수량 비율은 163.0%, 유입량/저수량 비율은 137.0%였다. 넷째, 대아저수지를 l0m 높인 경우 대아-경천 병렬 연계를 고려한 봉동 지점의 유량을 분석한 결과 유황은 연평균하여 풍수량 28.09 ㎥/s,평수량 1.79㎥/s, 저수량 0.89㎥/s, 갈수량 0.82㎥/S로 분석되어 유량증가 효과는 전혀 나타나지 않았다. 요약하면 대아저수지 용량을 증가시키더라도 용수공급의 증가효과는 전혀 나타나지 않았으며, 봉동지점의 고시유량을 확보하기 위한 대아저수지의 숭상의 수문학적 타당성은 전혀 없는 것으로 분석되었다. The objective of this study is to evaluate the hydrological feasibility of heightening the Dae-ah reservoir in order to save instream flow at the Bong-dong station situated in the Mankyoung river. The results are summarized as follows. Firstly, from the Dong-sang and Dae-ah cascaded reservoir's water balance analysis, water supply indexes of the Dae-ah reservoir were analyzed to have the rate of water supply divided by watershed area of 1207.4 ㎜, the rate of water supply divided by rainfall of 95.8%, the rate of water supply divided by inflow of 153.1%, the rate of water supply divided by storage capacity of 236.1%, and the rate of inflow divided by storage capacity of 200.6%. Secondly, from the Dae-ah and Kyoung-cheon paralleled reservoir's water balance analysis, flow durations at the Bong-dong station were analyzed to have the Q95 (the 95th high flow) of 28.95 ㎥/s, the Q185 (the 185th high flow) of 2.00㎥/s, the Q275 (the 275th high flow) of 2.00㎥/s, and the Q355 (the 355th high flow) of 0.82㎥/s. Thirdly, in case of heightening the full water level of the Dae-ah reservoir of 10m, from the Dong-sang and Dae-ah cascaded reservoir's water balance analysis, water supply indexes of the Dae-ah reservoir were analyzed to have the rate of water supply divided by watershed area of 1220.7 ㎜, the rate of water supply divided by rainfall of 96.8%, the rate of water supply divided by inflow of 154.6%, the rate of water supply divided by storage capacity of 160.0%, and the rate of inflow divided by storage capacity of 137.0%. Fourthly, in case of heightening the full water level of the Dae-ah reservoir of 10m, from the Dae-ah and Kyoung-cheon paralleled reservoir's water balance analysis, flow durations at the Bong-dong station were analyzed to have the Q95 of 28.09㎥/s, the Q185 of 1.79㎥/s, the Q275 of 1.79㎥/s, and the Q355 of 0.82㎥/s. The conclusion appeared not to have the hydrological feasibility of heightening the Dae-ah reservoir from the reason that increased storage capacity does not increase water supply amount any more because of the high rate of the water supply divided by inflow.

Plant regeneration from callus of Iris odaesanensis Y. N. Lee native to Korea via organogenesis

Bae, Kee-Hwa,Yoo, Kyoung-Hwa,Lee, Mi-Hyun,Jeong, Jae-Hun,Choi, Yong-Eui,Yoon, Eui-Soo The Korean Society of Plant Biotechnology 2013 식물생명공학회지 Vol.40 No.3

Iris odaesanensis Y. N. Lee. is an important endangered and native plant belonging to the family Iridaceae in Korea. This study describes a method for rapid micropropagation of this species via from leaf, rhizome and root explants derived calli. Leaf, rhizome and root explants were cultured on Murashige and Skoog (MS) medium supplemented with 2,4-dichlorophenoxy acetic acid (2,4-D) for callus induction. Rhizome explants yielded calli at a frequency of 72% when cultured at 1.0 mg/l 2,4-D. Calli were maintained at 1.0 mg/l 2,4-D. These calli were transferred to MS medium supplemented with 0, 0.5, 1.0, and 2.0 mg/l 2,4-D in combination with 0, 0.5, 1.0, and 3.0 mg/l BA for adventitious shoot induction. The highest number of adventitious shoot (228.9 per petri-dish) were formed at 1.0 mg/l 2,4-D and 1.0 mg/l BA. WPM medium was the best to convert calli into plantlets, where up to 98.2% of calli were regenerated into plantlets. This in vitro propagation protocol should be useful for conservation of this endangered plant.

열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

Mixer-settler를 이용한 용매추출로 에칭폐액로부터 철과 니켈의 분리

이만승,이경주,이진영,안재우,오영주 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.12

Solvent extraction and stripping experiments were conducted to separate iron from a spent FeC13 etching solution containing nickel. In the operation of mixer-settler, 7 extraction stages with 1.0 M Alamine336 in toluene, led to 98% extraction percentage of iron at equal phase ratio, when the flow rate of organic and aqueous were 35 mL/min and 5 mL/min, respectively. At equal phase ratio of aqueous to organic, 10 stripping stages with 0.01 M HC1 solution resulted in 99% stripping percentage of iron when the flow rate of stripping solution and loaded organic were 5 mL/min and 35 mL/min, respectively. The concentration of iron in the stripped solution was 133 g/L and this solution could be reused in the etching of nickel lead frame. (Received June 15, 2004)

요석환자에서 체외충격파쇄석술의 단독 치료 효과

이경규,이상철,김원재 충북대학교 의학연구소 2000 忠北醫大學術誌 Vol.10 No.1

연구목적: 최근 들어 요석의 치료에 있어서 체외충격파쇄석술이 우선적으로 시도되고 있는 방법 중 하나이다. 우리는 요석 환자에서 일차적 치료법으로 체외충격파쇄석술을 시행하고 이의 단독치료효과를 분석하였다. 대상 및 방법: 1996년 8월부터 2000년 4월까지 본원에서 요석으로 진단 받은 후 일차치료법으로 체외충격파쇄석술을 시행받고 3개월 이상 추적검사가 가능했던 424례를 조사하였다. 이중 남자는 260명, 여자는 164명으로 남자가 여자보다 1.59배 많았으며 환자의 평균 나이는 48.5세였다. 신장석의 경우 상부와 중부 및 하부 신배석으로 세분하였으며, 요관석은 역시 상부와 중부 및 하부 요관석으로 세분하였다. 결석의 위치와 크기 및 체외충격파쇄석술 시행횟수에 따른 성공률과, 시행 후 발생한 부작용에 대하여 분석하였다. 결과: 총 대상자 424명 중 신결석은 98례로 23.1%였고 요관결석은 312례로 73.6%였으며 14례에서는 방광석과 요도석이었다. 체외충격파쇄석술에 의한 총 성공률은 89.9%였으며 신장과 요관의 위치별로는 각각 82.7%. 92.3%의 성공률을 보였고 평균시술횟수는 각각 1.75회, 1.50회였다. 14례에서는 방광결석으로 체외충격파쇄석술을 시행하였으며 이중 85.7%에서 완전분쇄가 일어났다. 누적성공률별로는 신석의 경우 1회시 52.8%. 2회시 72.4%. 3회시 81.7%였으며 요관결석의 경우에는 각각 57.4%, 74.7%, 81.7%로 나타났다. 위치에 따른 쇄석 성공률을 비교하여 볼 때, 신석의 경우 하부 신배석의 쇄석 성공률(82.6%)은 중부(85.7%)나 상부 신배석(81.5%)의 성공률과 유의한 차이를 나타내지 않았으며(p=0.18), 요관석의 경우에서도 위치에 따른 쇄석 성공률은 각각 92.1%, 92.8%, 92.9%로 유의한 차이가 나타나지 않아 위치별 성적에는 차이가 없었다. 결석의 크기별로 볼 때 10mm 이하에서는 성공률이 92.2%였으나 10mm 이상에서는 성공률이 82.2%로 낮아져 두 군 사이에 유의한 차이를 나타내었다(p=0.003). 체외충격파쇄석술 후 합병증으로는 49례(11.6%)에서 발생하였는데 이중 돌길(steinstrasse)이 17례로 가장 많았으며, 시술 후 심한 통증으로 입원한 경우가 6례 있었고 급성신우신염이 2례에서 나타났다. 결론: 요석환자에서 일차적 치료법으로 체외충격파쇄석술의 단독치료를 시행하는 것은 합병증이 경미하면서도 높은 성공률을 기대할 수 있는 효과적이고 안전한 치료 방법이라 생각한다. Purpose: Extracorporeal shock wave lthotripsy(ESWL) is currently proposed for the first line treatment of most renal and ureteral stones. We evaluated the of ESWL as the initial treatment of urinary calculi. Materials and Methods : We retrospectively reviewed the data of 424 patients who had been underwent ESWL(Richard Wolf, Peizolith 2501) for the initial treatment of urinary stones and followed up at least 3 months from August 1996 to April 2000. Sex ratio(M:F) was 1.59:1 and their mean age was 48.5 years old, We analized the success rate of ESWL according to the location and size of stones and number of sessions as well ascomplications. Result : Of 424 patients, 98(23.1%) had renal stones, 312(73.6%) ureter stones, and 14 in bladder or urethra. The cumulative stone-free rates of first, second, and third session and final result for renal stones were 52.8%, 72.4%, 78.8%, and 82.7%, and for ureter stones, 57.4%, 74.7%, 81.7%, 84.9% respectively. As the size of urinary calculi increased, the numbers of ESWL sessions increased and the success rates were significantly reduced. In kidney, success rate of stone in lower calyx(82.6%) was similar to those of mid and upper calyx stone(85.7% and 81.5%). In ureter stones, success rates according to level were also not different(92.1%, 92.8%, and 92.9%, respectively) . According to the size of stones, the success rate for the stones smaller than 10mm in diameter was higher than those of over 10mm(92.2% vs 82.25). Post-ESWL complication were developed in 49 cases(11.6%) Including 17 cases of steinstrasse, 9 of renal colic, 2 of acute pyelonephritis, and 21 of minor discomfort. that were controlled by general measurement. Conclusion: We believe that ESWL is a effective and safe treatment modality for the initial treatment of urinary stones without significant complications.

增損五積丸(碑積方)이 사람의 各種 癌細胞株의 成長沮碍에 미치는 效果

李竝求,元秦喜,文錫哉,金東雄,元京淑,文九 한국전통의학연구소 2002 한국전통의학지 Vol.12 No.1

chemosensitivity test of Geungsonojukwhan-Bijukbang was performed on the three different human cancer cell lines originated from liver, cervix and colon tissue, namely Hep 3B, Hela and HCT-15, which have similar doubling times. Semiautomated sulforhodamine B(SRB) assay appears to offer an valuable tool for chemosensitivity of unknown compounds, since it is a simple, valid and inexpensive method of assessing drug monitoring for large samples in a short time. The results obtained in this study were as follows 1. Good correlations were shown from the results of SRB assay and those of clogenetic assay. 2. As a result of exposure to Geungsonojukwhan, the proliferation of Hela cell and Hep 3B cell was slightly decreased in Geungsonojukwhan-Bijukbang(GIP), Geungsonojukwhan-Pejukbang(LUP) and Geungsonojukwhan-Sinjukbang(RTP). 3. As a result of exposure to Geungsonojukwhan, GIP showed better anticancer effect to HCT-15 cell lines than those of LUP and RTP. 4. The extract of Geungsonojukwhan-Bijukbang in 40℃ were more effective in cytotoxic response than those in 100℃. 5. The research showed that the higher concentration the more effective in the inhibition of proliferation of the cancer cell lines, however, the cytotoxic effect of Geungsonojukwhan-Bijukbang in the concentration of 1.60mg/㎖ and 3.20mg/㎖ showed the most effective inhibition rate according to the increase of concentration.

신장에 발생한 섬유육종 1례

이재규,손경민,권동득,오봉렬,류수방,박양일,최찬 大韓泌尿器科學會 2001 Korean Journal of Urology Vol.42 No.7