열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구

배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2

Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.

시금치주스, 비트주스, 오징어먹물을 첨가한 생면의 품질특성

심재호,김경미,배동호 한국산업식품공학회 2003 산업 식품공학 Vol.7 No.1

오징어먹물 2, 4%, 비트주스 6, 10%, 그리고 시금치주스 6, 10%를 첨가한 생면을 개발하여, 조리후의 물리화학적 및 관능적 특성을 비교하였다. 생면의 중량은 조리 후에 2.36~2.44배 늘어났으며, 수분 흡수율은 136~144%로 대조구와 비교할 때 유의적인 차이가 없었다. 색도 측정결과, 생면보다 조리면의 L값이 컸으며, 첨가물의 첨가량이 많을수록 L값은 감소하였다. 물리적 특성에서 인장강도는 대조구의 값이 가장 작은 반면, 오징어 먹물 2% 첨가한 생면이 대조구보다 9배 높았다. 신장율은 대조구의 값이 가장 높게 나타났지만, 오징어 먹물 4%를 첨가한 생면도 대조구와 유사하게 높은 값을 보였다. 견고성, 씹힘성, 뭉침성은 비트쥬스 10% 첨가면이 대조구에 비해 높았고, 응집성은 시금치주스 6% 첨가면이 가장 높았다. 접착성은 대조구가 다른 첨가면들과 큰 유의적 차이를 보였으며, 탄력성은 비트주스 6% 첨가면이 가장 높았다. 조리면의 관능검사 결과, 오징어 먹물을 4% 첨가한 면과 시금치주스를 10% 첨가한 면이 조직감 및 전체적인 기호도에서 가장 높은 평가를 받았다. The new colored noodles were produced by utilization of cuttlefish ink, beertroot juice and/or spinach juice in this study and the physico-chemical and sensory properties of the developed noodles were investigated before and after cooking. The weights of fresh noodles increased 2.36∼2.22 Times bymoisture adsorption after cookong. Moisture adsorption of the cooked noodles were higher in the cooked noodles with higher contents of additives and ranged 136 to 144%. The colors of the all fresh noodles and the cooked noodles containing cuttlefish ink or spinach juice were highly acceptable. The tensilw strength was highest in the cooked noodle containing 2% cuttlefish ink, which was 9 folds higher than regular noodle. The % elongations were highest in the regular cooked noodle and the cooked noodle containing 4% cuttlefish ink. In the textural property assays of cooked noodles, the cooked noodle containing 10% beetroot juice had higher values in hardness, chewingness and gumminess than the regular noodle. The chhensiveness was highest in the cooked noodle containing 6% spinach juice. The adhesiveness of the regular cooked noodle was significantly high, compared to any developed noodle. The differences in springinesses of developed noodles were ignorable. The overall textural properties were influenced by the additives in noodles, however, the effects of concentrations of the additives were insignificant. The result of the sensory tests showed the highest values of all description in the cooked noodles containing 4% cuttlefish ink or 10% spinach juice, indicating the highest acceptability.

다중 연산을 고려한 XML 문서의 접근제어

반용호,문준선,박경순,배경만,김종훈 東亞大學校附設 情報技術硏究所 2004 情報技術硏究所論文誌 Vol.12 No.1

The growth in interchange of business and other sensitive data has led to increasing interest in access control. Access control for XML is receiving significant attention as XML is gaining popularity for storing and exchanging information. Until now, research on XML security has been focused on the security of data communication using digital signatures or encryption technologies. As XML is also used for a data representation of data storage, XML security comes to involve not only communication security but also managerial security. In this paper, we discuss an XML access control model and propose a technique that supports not only read operations but also update operations.

급속열처리 장비의 온도 조절기용 전력 제어장치의 설계

주동만,배민호,민경일 永同大學校 2000 硏究論叢 Vol.6 No.1

위상 제어방식을 이용한 급속 열처리 장비의 온도조절기용 전력 제어장치를 설계하는 방법을 제시한다. 본 논문에서 제시된 설계 방법에 따라 전력제어장치를 제작 · 실험한 결과 가변입력제어신호(0~10 V)에 대해 가변출력평균전압(0~198.06 V), 제어 분해능 48.356 mV(12bit)를 얻었다. The method of designing power controller for temperature control of rapid thermal processing by using phase control method is presented. The power controller is fabricated by using design method presented is this method. The experimental results show that variable output average voltages are 0∼ 198.06 V and control resolution is 48.356 mV(12bit) at variable input control signal voltage range(0~ 10 V)

GPS와 IMU에 의한 구조물 변형 검색

이재원,백기석,배경호 東亞大學校 大學院 2004 大學院論文集 Vol.29 No.-

Such social structures as bridges, buildings, dams and towers have been transformed by their own load or fundamental ground. They have been behaved by other external causes. These regular or irregular behaviors threaten to do their users safety. Therefore, to monitor the load of the structures or reaction shown by them could help to verify their behaviors. RTK GPS allows the use of a static base station and remote rover unit to allow for data collection within several seconds and in real time. It is useful for monitoring the behaviors of massive structures like bridges. In this Study, Among GPS methods, we used RTK GPS to analyze the precision of monitoring and then on the basis of it, we developed a monitoring system using RTK GPS when measured the behavior of main tower of a suspension bridge by using RTK GPS. Comparing a deviation between observation values, X axis was 1mm, Y axis was 1mm and Z axis 2.2mm. It turned out that it was possible to monitor and measure structures by RTK GPS.

폴록사머 및 프로필렌글리콜을 이용한 클로트리마졸 고형 좌제의 물리화학적 특성

현경희,오유경,김정애,공경환,김지현,양준호,배명수,김호동,이종달,장현욱,용철순,최한곤 한국약제학회 2005 Journal of Pharmaceutical Investigation Vol.35 No.2

To develop a clotrimazole-loaded solid suppository with poloxamer and propylene glycol, the melting points of various formulations composed of poloxamer 188 (P 188) and propylene glycol were investigated. The dissolution study of clotrimazole delivered by the suppository composed of P 188 and propylene glycol was performed. The mixtures composed of P 188 and propylene glycol were homogeneous. Propylene glycol affected the melting points of poloxamer mixtures. In particular, the mixture [P 188/propylene glycol (70/30%)] with the melting point of about 32°C was a solid form at room temperature and instantly melted at physiological temperature. Furthermore, propylene glycol affected greatly the dissolution rates of clotrimazole from the suppository. Dissolution mechanism analysis showed the dissolution of clotrimazole was proportional to the time. Our results indicated that the solid suppository with P 188 and propylene glycol would be a candidate of rectal dosage form for clotrimazole.

상시관측소를 이용한 Single RTK-GPS 정밀도 비교

박운용,차성렬,배경호 東亞大學校建設技術硏究所 2004 硏究論文集 Vol.28 No.1

The plenty of availability and high precision of GPS CORS is the reason why it become important more and more in the fields of surveying widely. In this study. I extracted the arbitrary point's coordinate which is using GPS CORS data. now served in RINEX FORMAT via Inter-Net, with observation network of the existing triangulation and GPS CORS data. Then. with this arbitrary point as reference station. RTK GPS was performed. And I will study VRS-GPS concept which reduces the time and cost in the fields of surveying.

항공기용 가스터어빈 엔진의 재료선정을 위한 DATA BASE 개발

金學奉,林慶鎬,金光培,夫俊洪,柳常新 한국항공대학교 1991 論文集 Vol.29 No.-

본 논문의 목적은 항공기용 가스터어빈 엔진의 재료선정을 위한 데이타 베이스를 구축하는 것이다. 한 엔진설계자가 어떤 엔진요소에 사용 할 재료를 선택한다는 것은 매우 어려운 작업이다. 따라서 수 많은 재료에 대한 정보를 관리 할 수 있는 데이타 베이스가 절실히 요구되고 있으나, 국내에서는 아직 이 방면의 기초연구가 이루어져 있지 않은 실정이다. 온도, 압력, 회전수등 각 부분에서의 작동조건은 다른분야에 의해 제공될 것이다. 본 연구에서는 재료공학적 관점에서 재료의 대표적성질로서 고온강도, 내식성, 내산화성, 항복강도, 열팽창계수, 융점등을 고려해서 후보재료를 선정할 수 있도록 하였다. 이외에도 성형성이나 제조단가등도 고려해야할 변수가 된다. 본연구의 결과 사용자의 편의를 고려한 전산프로그램이 개발되었으며, 이를 이용하여 새로운 재료정보의 입력, 요구 재료선정 및 선정결과의 출력등이 가능하다. 끝으로, 선정된재료에 대한 재료공학적 검토도 실시하였다. The purpose of this study is to develop a data base for material selection of gas turbine engines. Since it is very diffcult task for a design engineer to select materials of adequate properties for specific engine components, a good data base is strongly desired to manage informations on various kinds of materials. However, no basic research is reported in this area so far in our country. The operating conditions such as temperature, pressure, rpm of spools are assumed to be provided by other mechanical studies. Creep rupture strength, corrosion resistance, yield strength, thermal expansion, melting point, etc., are considered as typical properties in this study to search a group of candidate materials. Formability, manufacturing or purchase cost can also be important variables to be considered. As a result of this study, a user-fiendly computer program has been developed for input of new material information, interactive material selection, and output of selection results. Finally, discussion is presented from the viewpoint of materials engineering.

치주조직 재생을 위한 칼슘 포스페이트 글라스 분말이 백서 두개골 결손부의 골조직 재생에 미치는 영향

이용근,문현주,이상배,김광만,김경남,최성호 大韓齒科器材學會 2003 대한치과재료학회지 Vol.30 No.2

The treatment of the tone defects resulting from trauma, neoplasm, surgery, or infection is one of the major concern in dentistry. The major goal is the functional, esthetical regeneration of supporting structures already destructed by disease. Transplantation technique have been used to provide a scaffold for bone regeneration, to augment bony defects resulting from trauma or surgery, to restore bone loss caused by dental disease, to prevent the collapse the alveolar ridge in recent extraction sites, to replace bone loss by periodontal disease, to augment the alveolar ridge in implant surgery. There are autogeneous, allogenic, xenogenic and alloplastic bone-grafts in transplantation. Among the alloplastic bone-graft materials, calcium phosphates have been received the most attention. In this study, the critical size defects were surgically produced in the calvarial bone of Sprague-Dawley rats using the 8 ㎜ trephine bur. Calcium phosphate glass powders with mean diameter 400 ㎛ transplanted onto the produced detects in the experimental group, while sutured without grafting anything in the control group. Histomorphometric as well as radiodensitometric analyses were performed after sacrifice at 2, 4 and 8 weeks following operation. The prepared calcium phosphate glass powder with average size 400 ㎛ in CaO-CaF_2-P_2O_5-MgO-Al_2O_3 promoted new bone formation in the calvarial defects in the Sprague-Dawley rats. New bone was formed in the upper side of the detects as well as the defect margin and dura mater. Experimental group always exhibited higher values in the length, area and density of the newly formed bone than that of the control group. There were significant differences between the experimental and the control groups, except the density after 4 weeks (p<0.05).

치주조직 재생을 위한 칼슘 포스페이트 글라스가 MC3T3-E1 세포의 증식, 분화 및 석회화에 미치는 영향

이용근,송진,이상배,김경남,최성호 大韓齒科器材學會 2003 대한치과재료학회지 Vol.30 No.2

The purpose of this work was to exploring the influence of the prepared calcium phosphate glass on the proliferation, differentiation, and mineralization of the culture system of the pre-osteoblastic MC3T3-E1 cells. Polystytene was employed as a control in this experiment. Cells were cultured in a differentiated medium onto the calcium phosphate glass as well as polystyrene, and the number of cells and the protein contents were determined. To examine osteoblast differentiation, the alkaline phosphatase activity was measured. Mineralization was evaluated by staining the calcium deposit with Alizarin red. Culture onto the calcium phosphate glass exhibited no significant difference in cell proliferation compared with control group. The alkaline phosphatase activity in the experimental group, however. was enhanced In the calcium phosphate glass significantly at 10-18 days than that of the control group (p<0.05). Enhancement of bone-like tissue formation by the addition of the calcium phosphate glass was observed since 7 days. The results of the present study indicate that the prepared calcium phosphate glass promotes osteogenesis by increasing collagen synthesis and calcification of the extracellular matrix. It maybe due to greater calcium concentration in the culture medium released from the calcium phosphate glass.