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      • 멕시코와 네팔에서 도입한 고추 유전자원의 풋마름병 및 역병 저항성

        고보환,김정훈,전수경,이지선,김병수 慶北大學校 農業科學技術硏究所 2005 慶北大農學誌 Vol.23 No.-

        Above 130 accessions of pepper consisting of 50 introductions from Mexico and Nepal, and resistant and susceptible controls were tested for resistance to bacterial wilt and to Phytophthora root rot at seedling stage by artificial inoculation. As the results, KC897, KC939, KC936 were newly found resistant to bacterial wilt in addition to already known resistance sources such as KC126, KC350, KC351, KC353. No new sources of resistance to Phytophthora root rot were found among the introductions from Mexico and Nepal.

      • 양수 알파태아단백과 태아핵형과의 상관관계

        고경심,오보훈 단국대학교 1998 論文集 Vol.33 No.-

        Amniotic fluid alpha-fetoprotein measurement is widely used to detect not only open neural tube defects but also other congenital anomalies. Our aim is to anlayse the relationship of amniotic fluid alpha-fetoprotein and fetal karyotyping. We include 1536 midtrimester pregnant women undergoing amniocentesis to detect fetal chromosomal abnormality in the cytogenetic laboratory at Dr. Oh’s genetic clinic and at Dankook University Hospital from February 1996 to December 1997. The most common indication for amniocentesis was abnormal triple makers. Overall incidence of chromosomal aberration was 28.0:1000(43/1536). Among chromosomal aberration, these were 31 cases of numerical aberration, 11 cases of structural aberration and one case of mosaicism. Amniotic fluid alpha-fetoprotein declined by 15 weeks gestation and upper and lower cut-of values was estimated by the suggestion of U.K. Collaborative Study91979). Amniotic fluid alpha-fetoprotein concentration of the group of chormosomal aberration was within normal limit according to the corresponding gestational age. We could no find any relationship between the amniotic fluid alpha-fetoprotein and the chromosomal aberration.

      • SCOPUSKCI등재

        두경부 유리피판 26례 분석

        정복성,윤근철,심경보,고경석,한상훈 大韓成形外科學會 1993 Archives of Plastic Surgery Vol.20 No.3

        Twenty four patients(21 males and 3 females) aged 14 to 70 years underwent 26 microvascular free tissue transfers in head and neck reconstructions from April 1990 to July 1992 (27 months) . Nineteen cases were tumors in head and neck area, and four were acquired deformities such as burn alopecia, burn scar contracture of the neck, Romberg disease and frontal sinus infection, and one was hemifaclal microsomia. The free flaps were executed successfully in 15 upper aerodigestive tracts, in 2 scalps and 3 skull bases and in contouring and resurfacing six facial and cervical lesions. The selection of donor site was bases upon the location of defect and the volume of tissue required : the forearm free flap was used in 11 cases, the rectus abdominis in 5, the groin in 2, the jejunum in 2, the occipital scalp in one, the first toe web space in one, the latissimus dorsi in one, the serratus anterior in one, the parietotemporalis fascia in one and the omentum in one. The free tissue transfers were primarily indicated in all patients in our series and there was no flap failure. The complications were minimal and the morbidities low. A free flap in the head and neck area is not only the most expedient method of reconstruction but also either the most reliable or the only available one in some clinical situations.

      • KCI등재후보

        장천공이 발생한 비장티푸스성 D군 살모넬라 장열 1례

        이진호,허진국,나종천,김의석,이혜경,신보문,김석호,고행일 대한감염학회 2004 감염과 화학요법 Vol.36 No.4

        비장티푸스 살모넬라증에 의한 장열과 장천공은 매우 드물다 저자들은 방어기전의 손상이 없는 건강한 성인에서 비장티푸스성 D군 살모넬라 장열에 동반된 장천공이 발생한 예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. The case of enteric fever and bowel perforation caused by nontyphoidal Salmonella spp. is extremely rare. We report a case of a 28-year-old man who suffered from enteric fever with complicated a small bowel perforation, which is a known complication of S. typhi and S. paratyphi infections. The culprit later proved to be nontyphoidal group D Salmonella spp. in our case.

      • KCI등재

        한국수어 응용언어학 연구 동향 분석

        고인경(Koh, In-Kyung),윤병천(Yoon, Byung-Cheon),이보경(Lee, Bo-Kyung),이지민(Lee, Ji-Min) 한국청각·언어장애교육학회 2021 한국청각·언어장애교육연구 Vol.12 No.1

        이 연구의 목적은 지난 16년간 발표된 한국수어 응용언어학 관련 논문들의 동향을 분석함으로써 한국수어 응용언어학 연구의 현주소를 파악하는 데 있다. 2005년부터 2020년 사이에 발표된 국내 한국수어 관련 학술지 및 학술대회 논문집 106개에서 발표된 논문 211편을 분석하였다. 그 결과 연구 분야는 11가지로 분류할 수 있었으며 공학 분야 연구 논문이 116편(54.98%)으로 가장 많았다. 연구 방법에서는 개발 연구가 123편(58.29%)으로 가장 많았다. 한국수어 응용언어학 논문은 2019년에 32편(15.16%)으로 가장 많이 발표되었다. 전체 중 117편(55.45%)이 학술지로 발표되었고 우수 등재 3편(2.56%), 등재 91편(77.78%), 등재 후보 23편(19.66%) 순이었으며, ‘특수교육저널: 이론과 실천’에서 15편(7.11%)으로 가장 많이 발표되었다. 논문 전체 중 2인 저자가 60편(28.44%)으로 가장 많았고 가장 빈도 높게 사용된 주제어는 ‘수화’로 25편(22.94%)의 연구 논문에서 확인되었다. The purpose of this study is to analyze the research trends of Korean Sign Language(KSL) applied linguistics from 2005 to 2020 and identify the implications and characteristics of existing studies, and suggest directions for future research. As a result of analyzing a total of 211 research papers, research topics were revealed by 11 research fields, and KSL applied linguistics has been the most researched in engineering with 116 papers(54.98%). Developmental researches were the most with 123 papers(58.29%). The year in which research papers were published the most was 2019, with the largest number of 32 papers(15.16%). Of the total, 117 papers(55.45%) were published in the journal, followed by ‘Excel ent registered’for 3 papers(2.56%), ‘Registered’for 91 papers(77.78%), ‘Registered candidate’for 23 papers(19.66%). KSL applied linguistics research was published the most in ‘The Journal of Special Education’with 15 papers(7.11%), two authors were the most with 60 papers(28.44%), the most frequently used key word was ‘Sign Language’with 25 papers(22.94%).

      • KCI등재

        한국수어학 연구 동향 분석

        고인경 ( Koh In-kyung ),조희경 ( Cho Hee-kyung ),이보경 ( Lee Bo-kyung ),이지민 ( Lee Ji-min ),윤병천 ( Yoon Byung-cheon ) 한국특수아동학회 2021 특수아동교육연구 Vol.23 No.1

        연구목적: 이 연구는 2005년~2020년 동안의 국내 한국수어학 연구 동향을 분석하여 객관적이고 체계적인 기초 자료를 제공하고, 향후 한국수어학의 연구 방향을 설정하는 데 목적이 있다. 연구방법: 국내 학술지 및 연구지에 게재된 총 52편의 한국수어학 연구 논문을 분석 대상으로 하여 일반적인 특성과 방법론적인 특성을 분석하였다. 연구결과: 연구 논문이 가장 많이 발표된 해는 2018년이었으며 학술지를 통해 발표된 연구 논문이 50편으로 가장 많았다. 학술지 중 45편이 ‘등재’로 등록되었으며 한국수어학 연구는 ‘특수교육 저널: 이론과 실천’에서 가장 많이 발표되었다. 연구자는 단독 저자가 28편으로 가장 많았다. 한국수어는 형태론에서 가장 많이 연구되었고 연구 방법으로는 문헌 연구가 26편으로 가장 많았다. 수어를 연구자가 직접 수집하여 분석한 경우에는 대부분 농성인을 언어제공자로 하였다. 52편의 연구 논문에서 가장 자주 쓰인 핵심어는 ‘한국수어’였다. 결론: 이상의 결과로 2005년부터 2020년까지의 한국수어학 연구 동향을 고찰하고 향후 연구 방향에 대해 논의에서 다루었다. Purpose: The purpose of this study is to analyze the research trends of Korean Sign Language(KSL) linguistics from 2005 to 2020 in Korea and identify the implications and characteristics of existing studies, and suggest directions for future research. Method: A total of 52 KSL linguistic research papers published in Korean journals and research magazines were analyzed for general characteristics and methodological characteristics. Results: The year in which research papers were published the most was in 2018, 45 of them were 'Registered' as journal. 'KSL Linguistics' research was published the most in 'The Journal of Special Education', with single authors being the most. In addition, KSL has been studied the most in morphology, and KSL of most Deaf adults was collected and analyzed. Among 52 research papers, the most frequently used key word was “Korean Sign Language”. Conclusion: The above results were compared with previous studies, and the future direction of KSL linguistic research and the necessity of subsequent studies were discussed in the discussion.

      • Clinical Features and Treatment Outcomes of Langerhans Cell Histiocytosis: A Nationwide Survey From Korea Histiocytosis Working Party

        Kim, Bo Eun,Koh, Kyung-Nam,Suh, Jin Kyung,Im, Ho Joon,Song, Joon Sup,Lee, Ji Won,Kang, Hyoung Jin,Park, Kyung Duck,Shin, Hee Young,Choi, Hyoung Soo,Lee, Soo Hyun,Yoo, Keon Hee,Sung, Ki Woong,Koo, Hong by Lippincott Williams Wilkins. 2014 Journal of pediatric hematology/oncology Vol.36 No.2

        A nationwide survey was conducted to clarify the clinical features and outcomes of Korean children with Langerhans cell histiocytosis (LCH). Korea Histiocytosis Working Party analyzed the data of 603 patients who were diagnosed with LCH between 1986 and 2010 from 28 institutions in Korea. Median age at diagnosis was 65 months (range, 0 to 276 mo). Bone was the most frequently affected organ (79.6%) followed by skin (19.2%). Initially, 419 patients (69.5%) had single-system involvement (SS), 85 (14.1%) with multisystem (MS) disease without risk organ involvement (MS-RO), and 99 (16.4%) multisystem disease with risk organ involvement (MS-RO). The 5-year overall survival (OS) rates in the SS, MS-RO, and MS-RO groups were 99.8%, 98.4%, and 77.0%, respectively (P<0.001), and the 5-year reactivation rates were 17.9%, 33.5%, and 34.3%, respectively (P<0.001). The OS rate was lower in patients with RO involvement (P=0.025) and lack of response to initial treatment (P=0.001). MS involvement (P=0.036) was an independent risk factor for reactivation. Permanent consequences were documented in 99 patients (16.4%). Reactivation of disease, MS involvement, and age at diagnosis ≤2 years were associated with higher incidence of permanent consequences. This study emphasized that further efforts are required to improve survival of MS-RO patients and reduce reactivation in younger patients with MS involvement.

      • SCOPUSKCI등재

        아토피피부염 환자에서 Interleukin-10 , Tumor Necrosis Factor - beta ( TNF-β ) 유전자의 다형성에 관한 연구

        고보경(Bo Kyung Koh),김정수(Jung Soo Kim),한훈(Hoon Han),이권행(Kweon Haeng Lee),김진우(Jin Wou Kim) 대한피부과학회 2002 대한피부과학회지 Vol.40 No.5

        N/A Background : Atopie dermatitis (AD) is a common inflammatory skin disease. Atopic dermatitis is associated with increased IL-4, IL-5, IL-10 and IL-13 but decreased 1NF-γand TNF production. IL-10 production has peen implicated in autoimmunity because of its effect on B-cell proliferation and antibody production. The study of IL-10 gene polymorphism is of interest because of the pivotal role of IL-10 In the regulation of inflammatory and immune responses. TNF-β significantly upregulates INF-γ but downregulates IL-5, IL-13 and IgE, which suggests a potential role of TNF-β in the pathogenesis of atopie dermatitis. Objective : We have investigated polymorphism of IL-10 promoter gene and TNF-α gene. Methods : Seventy one patients with atopie dermatitis and one hundred and sixty six normal subjects participated in this study with analysis of polymorphism of IL-10 promoter (-1082), (-819) gene and seventy one partions dermatitis and hundred and forty one normal subject participated in the analysis of polymorphism of TNF-β gene. The patients in this study were recently diagnosed with atopie dermatitis. Results : The frequency of IL-10 promoter (-1082) genotypes (A/A, A/G, G/G), genes (A, G), IL-10 promoter (-819) genotypes (T/T, T/C, C/C) and genes (T, C) did not show any significant difference between atopee dermatitis patients and normal controls. There was no sigmificant defference in the frequency of TNFB genotypes (TNFB^☆1/ /TNFB^☆1, TNFB^☆1/TNFB^☆2, TNFB^☆2/TNFB^☆2) and genes (TNFB^☆1, TNFB^☆2) it patients of atopie dermatitis and normal controls. Conclusion : The result of this study suggest that the other regions of the IL-10 promoter gene and TNFB gene should be investigated for polymorphism of atopie dermatitis. And the difference of IL-10 promoter TNFB gene polymorphism between caucasian and Korean needs to he evaluated.

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