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      • 영화 기생충의 계급 연구

        호예적 ( Yi-di Hao ),주종우 ( Jong-woo Joo ) 중앙대학교 예술문화연구원 2022 예술문화융합연구 Vol.17 No.-

        Since its release, Parasite has won Palme d 'Or at the 72nd Cannes International Film Festival and Best Picture, Best Director, Best International Film and Best Original Screenplay at the 92nd Academy Awards ceremony. In this film, the director Bong Joon-ho goes straight to the pain point of social reality, focusing on the increasingly difficult to cross the rich and poor class. With the help of excellent audio-visual language and text symbols, the use of stairs, Windows, interior space and other images, the use of superb narrative skills and exquisite audio-visual language to construct a multi-level, h-depth metaphor system, so that the film not only has multiple interpretation space, but also rich in deep philosophical connotation, pushing its realistic irony to the climax.

      • 중국 내 한국 드라마의 영향력 -펜트하우스 등 막장 드라마를 예로 들어-

        호예적 ( Yi-di Hao ),주종우 ( Jong-woo Joo ) 중앙대학교 예술문화연구원 2022 예술문화융합연구 Vol.17 No.-

        At the center of the Korean drama wave in China that began in the late 1990s, South Korean dramas have attracted a lot of attention from Chinese viewers. The Korean drama Penthouse was popular not only h Korea but also in China. The Makjang drama Penthouse, starring Kim Soon-ok's Eugene, Kim So-yeon, Lee Ji-ah, and Eom Ki-joon, is a story of revenge, derelment, and money trading, all told by the children of a chaebol family in the Republic of Korea, who live in a 100-story luxury apartment (called the Palace of Hera) in order to gain fame without any means or methods. Penthouse screenwriter Kim Soon-ok can say that the script is well written. It has gained popularity among Chinese audiences of 20 generations. During its broadcast, Penthouse received tens of billions of hits on several major Chinese social media sites, including Weibo, tictok and other platforms. Based on the questionnaire, this study will analyze the reasons for the popularity of Penthouse in China from two Chinese social media - Tik Tok and Weibo.

      • KCI등재

        Electron Heating and Current Scaling in a Two-dimensional Electron System in Close Proximity to Nanoscale Scatterers

        Yi-Ting Wang,Chun-Kai Yang,Sheng-Di Lin,Chi-Te Liang 한국물리학회 2014 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.64 No.10

        We have performed magneto-transport measurements on a two-dimensional electron system(2DES) which is in close proximity to nanoscaled scatterers. Weak localization, as evidenced bynegative magnetoresistance, is observed. In this work, we use the extracted phase coherence rateas a thermometer to measure the electron’s effective temperature Te in our 2DES when a highdriving current I flows through the device. We find that Te / I0.52, consistent with 1/ep T2in two dimensions, where 1/ep is the electron-phonon scattering rate. However, the phase coherencerate 1/ T, with a very small offset, is consistent with zero-temperature dephasing. Mostimportantly, our experimental results are in agreement with the fact that at low temperatures, thedominant phase-breaking mechanism is electron-electron scattering, not electron-phonon scattering. Therefore we are able to investigate both electron-electron scattering and electron-phonon scatteringwhich are, in most cases, difficult to study independently in the linear region. Our data showthat the electron heating effect is a very powerful tool for studying semiconductor devices.

      • Planck Cold Clumps in the <i>λ</i> Orionis Complex. II. Environmental Effects on Core Formation

        Yi, Hee-Weon,Lee, Jeong-Eun,Liu, Tie,Kim, Kee-Tae,Choi, Minho,Eden, David,II, Neal J. Evans,Francesco, James Di,Fuller, Gary,Hirano, N.,Juvela, Mika,Kang, Sung-ju,Kim, Gwanjeong,M. Koch, Patrick,Lee, American Astronomical Society 2018 The Astrophysical journal, Supplement series Vol.236 No.2

        <P>Based on the 850 mu m dust continuum data from SCUBA-2 at James Clerk Maxwell Telescope (JCMT), we compare overall properties of Planck Galactic Cold Clumps (PGCCs) in the lambda Orionis cloud to those of PGCCs in the Orion A and B clouds. The Orion A and B clouds are well-known active star-forming regions, while the A Orionis cloud has a different environment as a consequence of the interaction with a prominent OB association and a giant H-II region. PGCCs in the lambda Orionis cloud have higher dust temperatures (T-d = 16.13 +/- 0.15 K) and lower values of dust emissivity spectral index (beta = 1.65 +/- 0.02) than PGCCs in the Orion A (T-d = 13.79 +/- 0.21 K, beta = 2.07 +/- 0.03) and Orion B (T-d = 13.82 +/- 0.19 K, beta =1.96 +/- 0.02) clouds. We find 119 substructures within the 40 detected PGCCs and identify them as cores. Out of a total of 119 cores, 15 cores are discovered in the lambda Orionis cloud, while 74 and 30 cores are found in the Orion A and B clouds, respectively. The cores in the lambda Orionis cloud show much lower mean values of size R = 0.08 pc, column density N(H-2) (9.5 +/- 1.2) x 10(22)cm(-2) , number density n(H-2) - (2.9 +/- 0.4) x 10 5 CM -3 , and mass M-core = 1.0 +/- 0.3 M(circle dot)compared to the cores in the Orion A [R = 0.11 pc, N(H-2) = (2.3 +/- 0.3) x 10(23) cm(-2), n(H-2) = (3.8 +/- 0.5) x 10(5)cm(-3) , and M-core = 2.4 +/- 0.3 M-circle dot] and Orion B [R = 0.16 pc, N(H-2) (3.8 +/- 0.4) x 10(23) cm(-2), n(H-2) = (15.6 +/- 1.8) x 10(5) cm(-3) , and M-core = 2.7 +/- 0.3 M-circle dot] clouds. These core properties in the A Orionis cloud can be attributed to the photodissociation and external heating by the nearby H rr region, which may prevent the PGCCs from forming gravitationally bound structures and eventually disperse them. These results support the idea of negative stellar feedback on core formation.</P>

      • KCI등재

        Thrombin promotes epithelial ovarian cancer cell invasion by inducing epithelial-mesenchymal transition

        Yi-Cun Zhong,Ting Zhang,Wen Di,Wei-Ping Li 대한부인종양학회 2013 Journal of Gynecologic Oncology Vol.24 No.3

        Objective: Over-expression of thrombin in ovarian cancer cells is associated with poor prognosis. In this study, we investigated the role of thrombin in inducing epithelial-mesenchymal transition (EMT) in SKOV3 epithelial ovarian cancer cells. Methods: After thrombin treatment SKOV3 cells were subjected to western blots, reverse-transcription PCR, and enzyme-linked immunosorbent assay to quantify EMT-related proteins, mRNA expression of SMAD2, DKK1, and sFRP1, and the secretion of matrix metalloproteinases (MMPs) and cytokines. Meanwhile, invasion ability was evaluated using transwell assays. Results: The results indicated a dose- and time-dependent down-regulation of E-cadherin and upregulation of N-cadherin and vimentin in thrombin-treated SKOV3 cells, compared with the thrombin-free control group (p<0.05). There was a dose-and time-dependent increase in the levels of SMAD2 and DKK1 mRNAs and a decrease in the levels of sFRP1 mRNA in thrombin-treated SKOV3 cells compared to control cells (p<0.05). Thrombin-treated SKOV3 cells exhibited increased secretion of MMP-9, MMP-2, interleukin (IL)-8, and IL-6 and increased invasion compared to untreated cells (p<0.05). Thrombin altered the morphology of SKOV3 cells to a spindle-like phenotype. Addition of hirudin to thrombin-treated cells reversed the effects of thrombin. Conclusion: Thrombin induced EMT and promoted the invasion of SKOV3 cells, possibly via distinct signaling pathways. Hirudin inhibited the effects of thrombin, suggesting that anticoagulant therapy could be a novel therapeutic strategy for ovarian carcinoma.

      • Knowledge of Cervical Cancer Screening among Health Care Workers Providing Services Across Different Socio-economic Regions of China

        Di, Jiang-Li,Rutherford, Shannon,Wu, Jiu-Ling,Song, Bo,Ma, Lan,Chen, Jing-Yi,Chu, Cordia Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.6

        Background: China carries a heavy burden of cervical cancer (CC) and substantial disparities exist across regions within the country. In order to reduce regional disparities in CC, the government of China launched the National Cervical Cancer Screening Program in Rural Areas (NCCSPRA) in 2009. Critical to the success of the program are the health care workers who play a pivotal role in preventing and managing CC by encouraging and motivating women to use screening services and by providing identification and treatment services. This study aimed to assess cervical cancer knowledge among these health care workers at the county level in maternal and child health (MCH) hospitals across different socio-economic regions of China. Materials and Methods: A cross-sectional survey was conducted and self-administered questionnaires were sent to all health care workers (a total of 66) providing cervical cancer screening services in 6 county level MCH hospitals in Liaoning, Hubei and Shaanxi provinces, representing eastern, central and western regions of China; 64 (97.0%, 64/66) of the workers responded. ANOVA and Chi-square test were used to compare the knowledge rate and scores in subgroups. Results: The knowledge level of the respondents was generally low. The overall combined knowledge rate was 46.9%. The knowledge rates for risk factors, prevention, clinical symptoms, screening and diagnostic tests and understanding of positive results were 31.3%, 37.5%, 18.1%, 56.3% and 84.4%, respectively. Statistically significant differences in scores or rates of CC knowledge were seen across the different regions. The total and sectional scores in the less developed regions were statistically significantly lower than in the other regions. Conclusions: The majority of the health care workers who provide CC screening service in NCCSPRA at county level MCH hospitals do not have adequately equipped with knowledge about CC. Given the importance of knowledge to the program's success in reducing CC burden in rural women in China, efforts are needed to improve the knowledge of health care workers, especially in less developed regions.

      • KCI등재

        Sulfakinin inhibits activity of digestive enzymes in the brown planthopper, Nilaparvata lugens

        Guo Di,Zhang Su,Zhang Yi-Jie,Ma Jun-Yu,Gao Cong-Fen,Wu Shun-Fan 한국응용곤충학회 2020 Journal of Asia-Pacific Entomology Vol.23 No.4

        In animals, feeding can regulate release of digestive enzymes. Digestive enzymes are produced and released in response to specific ratios of nutrients, so the quality and quantity of food ingested are important factors in the secretion and activity of digestive enzymes. In general, the enzyme activity and secretion in the fed insects are relatively higher than that in the unfed insects. Neuropeptides and peptide hormones are important regulators of enzyme activity. In several insects, the neuropeptide sulfakinin (SK) is known to be a regulator of feeding and digestion similar to cholecystokinin in mammals. However, the roles of diet and SK in regulation of activity of digestive enzymes in the important pest insect, the brown planthopper (Nilaparvata lugens), are unknown. In this study, we identified six genes encoding different digestive enzymes and cloned three of these. We found that enzymatic activity and transcriptional levels of digestive enzymatic activity genes were upregulated by refeeding animals for 5 h after 24 h starvation. Furthermore, injection of N. lugens SK reduces digestive enzyme activity and leads to a downregulation of digestive enzyme gene transcripts. This study provides new views into the action of diet and SK in regulation of digestive enzymes in (hemimetabolous) insects. Taken together with the roles of SK in inducing satiety, our data strongly suggest that SK signaling is important in regulation of food ingestion and processing.

      • KCI등재

        Betulinic acid prevents alcohol-induced liver damage by improving the antioxidant system in mice

        Jine Yi,Wei Xia,Jianping Wu,Li-yun Yuan,Jing Wu,Di Tu,Jun Fang,Zhuliang Tan 대한수의학회 2014 JOURNAL OF VETERINARY SCIENCE Vol.15 No.1

        Betulinic acid (BA), a pentacyclic lupane-type triterpene, hasa wide range of bioactivities. The main objective of this workwas to evaluate the hepatoprotective activity of BA and thepotential mechanism underlying the ability of this compoundto prevent liver damage induced by alcohol in vivo. Mice weregiven oral doses of BA (0.25, 0.5, and 1.0 mg/kg) daily for 14days, and induced liver injury by feeding 50% alcohol orally atthe dosage of 10 ml/kg after 1 h last administration of BA. BApretreatment significantly reduced the serum levels of alaninetransaminase, aspartate transaminase, total cholesterol, andtriacylglycerides in a dose-dependent manner in the miceadministered alcohol. Hepatic levels of glutathione, superoxidedismutase, glutathione peroxidase, and catalase wereremarkably increased, while malondialdehyde contents andmicrovesicular steatosis in the liver were decreased by BA in adose-dependent manner after alcohol-induced liver injury. These findings suggest that the mechanism underlying thehepatoprotective effects of BA might be due to increasedantioxidant capacity, mainly through improvement of thetissue redox system, maintenance of the antioxidant system,and decreased lipid peroxidation in the liver.

      • KCI등재

        Triterpenoid saponins from Clinopodium chinense (Benth.) O. Kuntze and their biological activity

        Yin-Di Zhu,Jing-Yi Hong,Feng-Da Bao,Na Xing,Ling-Tian Wang,Zhong-Hao Sun,Yun Luo,Hai Jiang,Xudong Xu,Nai-Liang Zhu,Hai-Feng Wu,Gui-Bo Sun,Jun-Shan Yang 대한약학회 2018 Archives of Pharmacal Research Vol.41 No.12

        Four new ursane-type triterpenoid saponins, clinopoursaponins A–D (1–4), six new oleanane-type triterpenoid saponins, clinopodiside VII–XII (5–10), as well as eight known triterpene analogues (11–18), were isolated from the aerial parts of Clinopodium chinense (Benth.) O. Kuntze. The structures of the new compounds were determined based on extensive spectral analyses, including 1D (1H and 13C) and 2D NMR experiments (COSY, NOESY, HSQC, 2D TOCSY, HSQC-TOCSY and HMBC), HR-ESI-MS and chemical methods. Compounds 1–18 were evaluated for their protective effects against anoxia/reoxygenation-induced apoptosis in H9c2 cells and cytotoxicities against murine mammary carcinoma cell line 4T1. Compounds 8, 9 and 18 exhibited significant protective effects, while compound 1 exhibited cytotoxic activity with IC50 value of 7.4 μm compared to 7.6 μm for the positive control 10-hydroxycamptothecin.

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