비만 여성을 대상으로 한 해조류 추출물의 국부처치와 운동 병행을 통한 지방분해 효과의 임상적 검정

서태수,이인숙,변재철,김규호,박승한,김유영,김상국,김현정,김상기,신동철,성미영,박종석,김종기,박언휘 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.3

This study was carried out to test the body fat breakdown during topical seaweed extract treatment and in combination with the aerobic exercise. Of 20 female obesity subjects, ten treated a cream types of seaweed extract(control group) and ten treated a placebo cream(placebo group). Topical treatment of each sample was designed for 4 weeks, and treated with 2 times a day about 10ml on the abdomen and the thigh, respectively. All subjects were participated aerobic dance half hour a day and four times a week. After 4 weeks of topical treatment and exercise, they were measured body fat, skinfold thickness, body circumference. Then venous blood samples were taken and analyzed blood cells, serum enzymes, and serum lipids. There were reduction of body weight, % of body fat, antebrachium, brachium, chest, waist, thigh circumference and abdomen thickness between pre and post treatment in both group. Especially, body weight and % of body fat significantly reduced in the subjects treating the seaweed extract than those treating the placebo. There were significant decrement in total cholesterol and LDL whereas increment in HDL and TBIL in the control group, but no significant difference in the placebo group. In conclusion, there were 7.6% of body fat reduction during 4 weeks of aerobic exercise and 21% of body fat reducement in combination of topical seaweed treatment and exercise, respectively. These results suggest that the topical treatment of seaweed extract should be very effective for fat breakdown. Especially, the body fat breakdown maximized in the combination with the topical seaweed extracts treatment and the aerobic exercise.

한국무속의 '신병'에 대한 진단분류연구

서동혁,이부영,신민섭,유희철 大韓神經精神醫學會 1996 신경정신의학 Vol.35 No.6

To study nosologically the Korean shaman's initiation sickness, 'Shin-Byong', the authors investigated 29 shamans with Symptom Check List-90-R(SCL-90-R) and questionnaire without visiting and interviewed 70 shamans using SCL-90-R, questionnaire and The Schedule for Affective Disorder and Schizophrenia-Lifetime(SADS-L). All shamans were located in Seoul. The results were as follows : 1) Among symptom groups of SCL-90-R, 'Shin-Byong' were associated with higher scores in depression, somatization, psychoticism and hostility group in descending order. 2) With DSM-Ⅲ-R classification, 87.2% of 'Shin-Byong' cases were mood disorders, Another 8.6% of cases were somatization and dissociative disorders and two disorders were related with dissociative phenomenon. Considering the diagnosis of manic episodes in this study, it seems to be a part of dissociative phenomenon, 'Shin-Byong' is the syndrome that is mainly composed of depression and disorders, which are related with dissociative phenomenon. 3) Shamans have teleologic thinking that 'Shin-Byong' is the phenomenon to receive spirits and diagnose intuitively. They think the main therapeutic method is recieving spirits, In conclusion, 'Shin-Byong' isn't a real disease entity but it is a shamanistic disease concept transformed during the shamanistic therapeutic process for depression patients with high dissociative tendency and dissociative disorder.

薄板의 加工性에 미치는 異方性에 관한 硏究(Ⅰ)

徐大敎,金東哲,禹鎬吉 충남대학교 공업교육연구소 1981 論文集 Vol.4 No.1

This study is concerned with the anisotropy which affects the workability of several different sheet metals. To do this, authors studied the earing through the deep drawing process, using the results which were obtained by studying the effect of the anisotropy of sheet metal in tensile yielding. The results through this study are as follows; 1) The corresponding maximum errors of the theoretical and experimental results in steel, brass, and aluminum plates in tensile yielding are 16%, 6%, and 5% respectively. 2) The earing of steel, brass and copper plates whose thickness are 0.62㎜ are two or three times as high as those of corresponding plates whose thickness are 0.34㎜. 3) The assumption of costa is satisfied in steel plate, but it is not satisfied in brass plate. It is hoped that the results of this study will be made reference to other works of sheet metal.

최적성장모형에 의한 거시경제의 안정성 및 수렴성 분석

서대진,박동철 진주산업대학교 1993 論文集 Vol.32 No.-

The Purpose of this study is to Analysis the stabilization and convergency of An optimum growth model in macro-economics. The results of the study are as follows. 1. We have a steady state and unique one. 2. We have the saddle point in the stabilization of the steady state. 3. The convergency of the Model is dependent of the paremeters α, σ. of the utility function and the production function.

미세주사법에 의한 P 인자를 벡터로 이용한 송사리의 형질전환에 관한 연구

김남철,성승현,서동상 성균관대학교 생명과학자원연구소 1996 生命資源科學硏究 Vol.2 No.2

어류의 형질전환 실험에 있어서의 두 가지 문제점은 어류의 수정란마다 독특한 특성을 갖고 있어 독특한 미세주입법이 요구된다는 점과 적절한 벡터계가 구축되어 있지 않다는 것이다. 본 연구는 어류의 형질전환에서 문제가 되는 난각의 단단함을 극복하는 미세주입법의 확립과 P벡터계의 유용성의 검증에 필요한 미세주입된 벡터의 생체 내 존재 여부를 검출하기 위한 방법조건 확립이라는 두 가지 목적을 가지고 수행하였다. 먼저 미세주입법에 있어서는 5% agar 평판을 지지체로 사용하여 바늘과 수정란을 동시에 고정시킴으로써 미세주입법을 수행할 수 있었으며 17.3%의 생존율을 보였다. 두 번째로 미세 주입이 되고 부화된 개체에 실제로 P벡터의 효과적인 미세주입이 수행되었고 생체 내에 어떤 방식으로든 그 벡터가 존재하는가를 검출하기 위해서는 PCR을 이용하였다. P벡터의 역반복 서열을 primer로 사용한 결과 5.1Kb의 증폭 산물이 관찰되었다. 이 두 방법은 앞으로 P벡터께의 유용성을 점진적으로 검증해 나가는데 유용하게 이용될 수 있을 것이다.

Heparin이 망내계세포에 미치는 영향에 관한 초미형태학적 연구

이동철,김중길,임정교,손윤경,서인수,손태중 慶北大學校 醫科大學 1991 慶北醫大誌 Vol.32 No.3

저자들은 heparin 투여후 세망내피계의 초미형태학적 변화를 관찰하기 위해 Sprague-Dawley계 숫쥐에 heparin과 endotoxin을 투여한 후 비장을 채취하여 실험에 이용하였다. 실험군은 heparin 전처치군과 heparin 후처치군으로 나누었으며 비교군으로 heparin 단독투여군과 endotoxin 단독투여군을 설정하여 각각을 투약후 비장을 채취하여 광학현미경 및 전자현미경적 검색을 실시하였다. 실험결과를 요약하면 heparin 단독투여군은 대식세포, 형질세포양 림프아구 및 다핵백혈구가 증가되었고, 대식세포의 탐식능도 항진되었다. 그러나 대식세포자체의 소기관 발달은 현저하지 않았다. Endotoxin 단독투여군은 시간이 갈수록 대식세포의 탐식능이 저하되고, 파괴가 증가되어 수가 감소하였다. 미소혈전이 자주 관찰되었으며 기타세포들의 파괴가 관찰되었다. Heparin 전처치 및 후처치군은 공히 endotoxin군에 비해 대식세포 탐식능이 증가되었다. 이상의 성적으로 보아 heparin의 망내세포에 대한 영향은 주로 대식세포의 탐식능과 수의 증가로 생각되며 이는 정상 및 병적상태 모두에서 일어난다고 생각된다. 또한 ET 투여 전후 heparin을 투여한 실험군에서 공히 대식세포 탐식능이 증가되었으므로 이는 ET shock 후 조직손상으로 분비되는 세망내피계 저하물질에 대해 heparin이 길항작용을 할 것으로 생각된다. 또한 heparin의 대식세포 탐식능항진에 대한 효과는 세포의 직접적인 자극이라기 보다는 탐식과정중 특히 oposonization에 효과를 미칠 것으로 생각된다. The authors studied an ultrastructural changes of reticuloendothelial system after administration of heparin. Male Sprague-Dawley rats were examined after administration of heparin and endotoxin. The experimental groups were divided into heparin pretreated groups and heparin posttreated groups. The control groups were divided into heparin-only groups and endotoxin-only groups. Each animals were sacrificed and spleens were extirpated and examined by light and electron microscopy. The results obtained were summarized as follows: Heparin-only groups showed proliferation of macrophages, lymphocytes and neutrophils. The phagocytic activity of marcophage is enhanced. The cytoplamic organellar change is not remarkable except increase of secondary lysosomes. Endotoxin-only groups showed decrease of phagocytic cells. The phagocytic activity is also depressed. Destruction of macrophages and other cells are noted. Microthrombi are frequently seen. Both heparin pretreated and heparin posttreated groups revealed relative enhancement of phagocytic activity compaired to endotoxin-only groups. From the result of the experimental study, it appears that the effect of heparin on the reticuloendothelial system is enhancement of phagocytic activity of macrophages both in the coditions of normal and pathologic one. And it also suggests that heparin may act as an antagonizing factor to the reticuloendothelial depressing agent that may be derived from injured organ of endotoxin shock. And the effect of heparin to the phagocytic activity of macrophage may be related to the process of phagocytosis such as opsonization or to the direct cellular stimulation.

外國人 直接投資에 대한 硏究 : 對外經濟證屬이 經濟成長과 所得分配에 미치는 影響에 관한 實증硏究

徐東錫,金洙槿,宋燮瑋,金喆煥 亞洲大學校 1985 論文集 Vol.8 No.-

Dependency theory claims that economic dependency retards economic development and increases income inequlity within peripheral countries. On the other hand, neoclassical development theory predicts that economic linkage to the world economy facilitates economic growth and improves the income distribution. This paper aimes to test the general validity of dependency theory by using a cross section data over 1970s and time series data over the period 1962-1984 of Korea. The time series data allow us to observe the dynamics of dependency theory which emphasizes the "historical process". Four measures of economic dependency or external linkage are used to regress the economic growth rate and Gini coefficients. The control variables additionally employed in our empirical analysis are exports and domestic capital formation. The research design employed is a regression analysis incorporating lag structure. The results indicate that economic dependency has no significant negative effects on growth and income distribution. Thus we conclude that the denpendency theory is not substantiated by our empirical data. The data rather supports the neoclassical development theory.

양성 갑상선 결절에서 티록신 억제 요법의 효과

윤석기,김철희,김영선,변동원,서교일,유명희 대한내분비학회 2000 Endocrinology and metabolism Vol.15 No.4·5

항우울제와 연관된 성기능 장애에 대한 조사

조성일,이영식,서동수,나철,민경준 한국정신신체의학회 2003 정신신체의학 Vol.11 No.1

기종성 신우신염 1례

이재욱,구정태,서정일,양창헌,이정호,이동철,이영현,이활,이경섭 동국대학교 경주대학 1997 東國論集 Vol.16 No.1

기종성 신우신염은 주로 당뇨병환자나 폐쇄성 요로질환을 가진 환자에 발생하며 특징적으로 신실질 및 그 주위조직에 가스를 형성하면서 심한 조직괴사를 일으키는 매우 드문 급성 화농성 신감염으로 사망률이 높은 질환이다. 이 질환은 1989년 Kelly와 MacCallum에 의해 처음 보고된 이래 외국문헌에 약 90례 정도가 보고되어 있으며 국내에는 28례가 보고되어 있다. 수액 및 전해질 보충, 인슐린 투여를 통한 적절한 혈당조절 및 항생제 투여등의 내과적 치료와 절개배농 및 신적출술등의 수술적 치료 방법이 있다. 내과적 치료로 가스의 감소가 없는 경우에는 즉각적인 수술적 치료를 시행하여야하므로 이 가스변화에 대한 추적관찰이 중요하다 하겠다. 본 저자들은 당뇨병환자에서 발생한 기종성 신우신염 1례를 내과적 요법을 치험하였기에 문헌고찰과 함께 보고하고자 한다. Emphysematous pyelonephritis is rare, life-threatening infection of the renal parenchyma and perirenal tisseue. This disease is characterized by the production of intrarenal and perirenal gas and is frequently encountered in patients with diabetes mellitus or urinary obstruction. We experienced a case of emphysematouse pyelonephritis in a 62 years old women with poorly controlled diabetes mellitus who had been managed with medical theraphy. So we report this case with a review of the referenced literatures.