정상 한국인에서 연령증가에 따른 혈장 Dehydroepiandrosteronesulfate ( DHEA-S ) 농도 및 DHEA - S / cortisol 비의 변화

박성우,유형준,임성희,최문기,유재명,박민숙,이권엽,박철수,김철홍,김현규,김두만,박규용 대한내분비학회 1997 Endocrinology and metabolism Vol.12 No.2

Backgroud: DHEA-S is the most abundant steroid hormone in circulation, and primarily secreted from the adrenal cortex, but its physiological role is little known. One of the characteristic features of DHEA-S is progressive decrement of plasma DHEA-S level with advancing age, in contrast, plasma levels of other adrenal hormones are not chaging or littie decreasing. To grasp the trends of plasma DHEA-S level and DHEA-S/cortisol ratio by age in healthy Korean, we measured the plasma DHEA-S levels and DHEA-S/cortisol ratios in healthy Korean. Methods: Healthy Korean(men: 99, women: 102, age range: 15-97 year old)were studied. Subjects were not taking drugs(such as glucocorticoid or androgenic medication) or cigarettes known to modify the plasma level of DHEA-S and cortisol, and had no evidence of hepatic, renal disease or hyperlipidemia as determined by serum lipid, bilirubin, SGOT, SGPT, BUN, creatinine. Data were analyzed by 10-year age group for men and women: i.e, 10-19, 20-29, 30-39, 40- 49, 50-59, 60-69, 70-79, 80-89 and 90 year or more. Plasma DHEA-S levels were measured by using a commercially available RIA kit with 125I labeled-DHEA-SO4(Coat-A Count DHEA-SO4), and for the measurement of plasma cortisol levels, commercial Gamma Coat TM[125I] Cortisol Radioimmunassay Kit was used. Results:. 1) In both men and women, plasma DHEA-S level showed high interindividual variation within the same age group. 2) There were individual sex differences in plasma levels of DHEA-S, in all age groups, plasma DHEA-S levels were significantly higher values for men than for women. 3) Maximum plasma DHEA-S levels(men; 237+-3.35 ug/dL, women; 108+-17.5 ug/dL) were at third decade in both men and women. 4) Both men and women showed the continuous decline in plasma DHEA-S level with age. These age-related decline was more prominent in men than in women(men; y= -3.152 * +292.6, r2= 0.8459, P$lt;0.05, women; y= -1.417 * +143.3, r2 = 0.7278, P$lt; 0.05). 5) As an index of aging, there was no stastical difference between DHEA-S and DHEA- S/cortisol ratio. Conclusion: In healthy Korean, there were high interindividual variation of plasrna DHEA-S levels. In both men and women plasma DHEA-S level was peak at third decade, and from when it declined progressively with age. These results suggest that although the reliability of single plasma DHEA-S measurement are limited, the decline of DHEA-S with advancing age might be a specific marker of endocrinologic hormonal milieu(aging index). Also, concerning to individual adrenal secreting capacity, we measured DHEA-S/cortisol ratio. But we did not found that plasma DHEA-S/cortisol ratio is superior to the plasma DHEA-S level as an aging index. (J Kor Soc Endocrinol 12:245-254, 1997)

자궁 경부 침윤성 편평세포암종의 E-cadherin 발현과 DNA Ploidy 분석에 대한 연구 -상피내 종양과의 비교-

김유진,허만하,이선경,설미영 대한병리학회 1997 Journal of Pathology and Translational Medicine Vol.31 No.6

다세대주택의 재건축에 대한 경제성 분석 연구 : 광명시의 사례를 중심으로 Focused on case studies of Gwang-myeong city

유진호,이만구,김용수 中央大學校 建設環境硏究所 2002 環境科學硏究 Vol.13 No.2

본 연구는 아파트 중심의 재건축 사업의 문제점에 대하여 그 대안으로서 제시되고 있는 다세대 주택을 대상으로 경제적 타당성 분석을 목적으로 하였다. 이를 위해서 경기도 광명시의 다세대 주택 재건축 사례를 유형별로 분류하고 일반 건설회사에서 사용하는 수익성 분석방법을 통하여 경제성을 분석·비교하였다. 본 사례 연구의 결과를 요약하면 다음과 같다. 1) 단독형 다세대는 기존 용적률121%에서 198%로 증가(+77%)되었고 평당이익은 111만원으로 분석되었다. 2) 연립형 다세대는 단독형 보다 2%적은 75%의 용적률 증가가 있었으며 평당이익은 단독형 보다 58만원 많은 169만원으로 분석되었다. 3) 변화형 다세대의 경우는 용적률이 64%증가되었고 평당이익은 세 가지 유형 중 가장 많은 213만원으로 분석되었다. 상기의 세 가지 유형 중 변화형 다세대 주택 유형이 가장 경제적으로 우수한 것으로 분석되었으며, 효과적 재건축 개발방안으로서 리모델링 사업의 선택적 적용과 인센티브제의 확대 적용이 필요할 것으로 판단된다. The purpose of this study is to analyze economic feasibility in the multi-family house reconstruction. The method of this study includes cases studies for multi-family houses in gwang-myeong city. The results of this study are as follows : 1)the single multi-family house is analyzed as follows : the floor area ratio is increased at 77% and the profit of one pyong(3.3㎡) is 1,110,000 won, 2) the duplex multi-family house : the floor area ratio is increased at 75% and the profit of one pyong(3.3㎡) is 1,690,000 won and 3) the varied multi-family house : the floor area ratio is increased at 64% and the profit of one pyong(3.3㎡) is 2,130,000 won. Therefore, the varied multi-family house of the three types is analyzed to be the most economical type.

점증적 요통 체조와 교육이 만성 요통환자의 근지구력, 유연성 및 통증에 미치는 영향

유승희,공성아,이만균 경희대학교 체육대학 한국체육과학연구소 2004 體育學論文集 Vol.32 No.-

This study was designed to investigate the effects of a 6-week progressive exercise, mainly calisthenics, and education for low back pain on muscular endurance, flexibility, and self-perceived pain in low back patients. Eighteen female patients, aged 48±6.84 years, were volunteered to participate in the study as subjects. Standing height, body weight, percent body fat, waist-hip ratio(WHR), sit-and-reach trunk extension, sit-up, back sit-up, and pain ratings were measured in pre test. Upon the completion of the pre test, they went through the six weeks of interventions composed of progressive exercise and education for the first four weeks and the exercise only for the last two weeks. Then, they were tested in the post test by the same manner as the pre test. The results of pre and post test were compared by the paired t-test. The main results of the present study were as fellows: First, there were no significant changes by the interventions in body weight and WHR, whereas percent body fat were reduced significantly by the interventions. Second, flexibility and muscular endurance were enhanced significantly by the interventions. Third, self-perceived low back pain ratings and perceive ratings of pain in the daily activities were reduced significantly by the six weeks of interventions. It was concluded that low back pain would be relieved by the progressive exercise and education for low back pain, and that the interventions would be helpful to prevent additional injuries by increasing the flexibility and muscular endurance.

마제신에서 발생한 유암종

김유진,허방,허만하 대한병리학회 1996 Journal of Pathology and Translational Medicine Vol.30 No.12

��켈촉매에 의한 메탄의 輾換反應에 관한 연구

柳萬馨 서울市立大學校 1984 論文集 Vol.18 No.-

This study is concerned on the conversion of methane with air into CO and H₂under free-catalyst and Ni-catalyst. The results are as follows: 1. When the mole ratio of oxygen to methane is 1.2 at 950℃ of reaction temperature under free-catalyst, the reaction efficiency of CO and H₂ for 1 mole of methane has the maximum value of 0.53 and 0.71 respectively. 2. The optimum reaction temperature is 950℃ under free-catalyst. 3. The optimum reaction temperature is 800℃ under Ni-catalyst and the reaction efficiency of CO and H₂for 1 mole of methane is 0.72 and 1.23 respectively. 4. The reaction temperature can be lowed by using Ni-catalyst and the reaction efficiency of CO and H₂can be increased to 3.58% and 71.8% respectively as compared with free-catalyst.

장기간의 걷기 트레이닝이 중년 여성의 체력과 혈액성분에 미치는 영향

유명근,이만균,문황운 경희대학교 체육대학 한국체육과학연구소 2004 體育學論文集 Vol.32 No.-

This study was designed to investigate the effects of a 12-week walking training on body composition, physical fitness, and blood variables in obese middle age women. Fourteen subjects who had percent of body fat over 30% were selected from the members of diet class of K pubic health center. Then they participated in the twelve weeks of walking training program. Before and after the training program, percent body fat, five items of physical fitness, and blood variables regarding to metabolism were measured and compared between pre and post test. Paired t-test was utilized to detect the mean difference between the pre and post test. The results of this study were as follows: First, after twelve weeks of training, PBF and weight of subjects significantly decreased(P<.05). Second, after twelve weeks of training, left grip strength of subjects did not change significantly, but right grip strength, back strength sit-and-reach, sit-up, and sargent jump increased significantly(P<.05). Finally, after twelve weeks of training, blood glucose and triglyceride of subjects did not change significantly, whereas total cholesterol decreased significantly. There was a significant increase in forced vital capacity(P<.05). According to these findings, it was concluded that walking training was effective on the decrease of percent body fat, enhancement of physical fitness, partial improvement of metabolism and pulmonary function in obese middle age women if the training was conducted for long period despite the intensity fo the walking was relatively low.

熱分解깨스의 再循環에 의한 바이오매스의 깨스化

柳萬馨 서울市立大學校 1986 論文集 Vol.20 No.1

In this study on the gasification of rice husk by the internal recycle of pyrolysis gas, the following results have been proved; 1. The gasification by the separated combustion and the internal recycle of the pyrolysis gas can be used for scaling up the gasification in co-current fluidized bed. 2. The internal recycle of pyrolysis gas can make the tar content of producer gas decrease greatly, and the gasification efficiency is the affected by the internal recycle. 3. In the gasification by the internal recycle of pyrolysis gas, lower heating value of producer gas is 4.500 KJ/Nm³, and the tar content in this producer gas decreases below 0.1 g/Nm³.

한국·미국·스페인 청소년의 태권도 수련이 인성교육에 미치는 영향

유창재,양정옥,이중숙,이상돈,김영수,조만태 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.14 No.6

The purpose of this study was to analyzed what effect Taekwondo training has upon Juvenile trainees in Korea, America, and Spain. to see if there is a significant difference in their Human nature Education. The subject of this study was set up as 547 Juvenile trainees who are including 183 Koreans, 185 Americans and 179 Spanish people belonging to gymnasia in their own countries, and sampling by purpose sampling. The means in this study is used to amend and complemented after confirming suitability of the contents in the questionnaire that is made on the basis of questionnaire Lee Chul Ho(1996). it is used as study means after modified, whether the substance of question is right in fitness and applicability or not, Reliability of the question, the range of Cronbach's a is showed from .7924 to .8450. The method of statistically analysis adapted one-way ANOVA, two-way ANOVA by using SPSS WIN 10.0 Program. The result of this study are as followed : First, it can be seen that American Juvenile and Spanish Juvenile show more significant change than Korean Juvenile in their Human nature Education by the Taekwondo training according to their nationality. Second, it can be seen that Juvenile who have had the Taekwondo training for more than from three to five year show more significant change in their emotion, sociability and attitude towards life than those who have had the same training for more than other period in their Human nature Education according to their Taekwondo training period. Third, as a result of analytic investigation of what effect the same training has upon the change factors in their Human nature Education in accordance with their training period and nationality, it can be seen that the training itself and nationality has the greater influence on them than the training period. Therefore, judging from the above findings, it can be proved that the Taekwondo training has much more significant and positive effect on Juvenile in their change of emotion, sociability and attitude towards life.

전류 비유 모델에 의한 초등학생의 전류 개념 변화 분석

유병길,강인석,김병철,남만희,박선희,소하연,윤희정,이영아,이하룡,전병문,정승호 부산교육대학교 과학교육연구소 2000 科學敎育硏究 Vol.25 No.-

There exists a major impediment to learning electricity which may illuminate why direct presentation of scientists' ideas is too aggressive a strategy. This impediment lies in thinking that electricity is used up and in envisaging the light bulb as a consumer. This view is based on a powerful idea which summarises much of our experience; it declares that 'things get used up', 'you cannot get something for nothing', and 'intuitive thinking'. To replace this view with scientific view, we made the analogy model. It is suggested that the analogy model is more effective in teaching electricity circuits than conventional teaching method.