한우 성별에 따른 등심의 육질특성 비교

최정석, 정동순, 최석현, 이상화, 김종희, 최양일 忠北大學校 農業科學硏究所 2011 農業科學硏究 Vol.27 No.4

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조혈모세포이식 환자에서 침습성 진균 감염에 대한 Micafungin의 예방 효과 및 안전성

김시현,이동건,최수미,권재철,박선희,최정현,유진홍,이성은,조병식,김유진,이석,김희제,민창기,조석구,김동욱,이종욱,민우성,박종원 대한감염학회 2010 감염과 화학요법 Vol.42 No.3

Background: Micafungin, a potent inhibitor of 1,3-β-D-glucan synthase, is a novel antifungal agent of the echinocandin class. In vitro study showed that micafungin was effective against Aspergillus species as well as Candida species, but clinical data on the prophylactic efficacy against invasive fungal infections (IFIs) other than candidiasis are still lacking. Materials and Methods: We identified 60 consecutive adult hematopoietic stem cell transplantation (HSCT) recipients who received at least 3 doses of micafungin during neutropenic period. Micafungin was started as an alternative in patients who were intolerant or had adverse events (AEs) to primary prophylactic antifungal agents. We retrospectively reviewed the medical records and analyzed the efficacy and safety of micafungin for prophylaxis against IFIs. Results: The patients either had autologous (n=9) or allogeneic (n=51: 1 syngeneic, 24 sibling, 26 unrelated donor) HSCT. Itraconazole oral solution (n=58) was the most frequently used first line antifungal agent for prophylaxis and was administered for median 11 days. The most frequent cause of switch to micafungin was vomiting (n=42). The duration of neutropenia and micafungin administration was median 13 and 12 days, respectively. A successful outcome was achieved in 45 (75%) patients. Empirical antifungal therapy was initiated in 13 (22%) patients. There were 2 cases (3.3%) of breakthrough fungal infections which comprised a probable invasive pulmonary aspergillosis and a possible invasive fungal sinusitis. There was no case of invasive candidiasis. A total of 53 (88%) patients experienced at least one AE regardless of causality during micafungin administration. The most frequent AEs were hypokalemia, vomiting, diarrhea, and elevated serum aspartate aminotransferase or alanine aminotransferase. Among the aforementioned AEs, only 1 case of diarrhea could be classified as a probable relation with micafungin when causality was assessed. There was no AEs that caused discontinuation of micafungin. Conclusions: Micafungin seems to be a safe and effective agent for prophylaxis of IFIs including aspergillosis as well as candidiasis in HSCT recipients. However, further large, prospective, and randomized comparative studies are warranted for aspergillosis.

그림 Grimm동화에 나타난 여성상과 남성상

최석희 한국독일어문학회 2000 독일어문학 Vol.11 No.-

Von insgesamt 211 Texten der Grimmschen Ma¨rchen ist die Zahl der Ma¨rchen mit den ma¨nnlichen Helden uberwiegend gro¨βer als die mit weiblichen Helden. Die weiblichen Helden fallen jedoch im Ma¨rchen mehr auf als die ma¨nnlichen, weil die bekanntesten Ma¨rchen fast alle weibliche Helden haben. In dieser Arbeit wird das Frauen- und Ma¨nnerbild der Grimmschen Ma¨rchen untersucht. Das Zustandekommen der Grimmschen Ma¨rchen und vor allem ihre weltweite Rezeption ist im ho¨chsten Maβe von und durch Frauen bestimmt. Das Bild der Frau in den KHM ist weithin abha¨ngig vom Weltbild der Erza¨hler. die die Gewa¨hrsleute der Grimms waren. Auβerdem entsprechen diese Figuren weitgehend dem Frauenbild des 19. Jahrhunderts. Der weibliche Held ist eine Frau. die ein unglu¨ckliches Schicksal hat. geduldig und tu¨chtig arbeitet. Fleiβ, Ordnung. Reinlichkeit. Demut. Tu¨chtigkeit, Passivita¨t. Schweigsamkeit und Keuschheit sind hervorstechende Eigenschaften der Heldinnen. Aber es gibt auch einige weibliche Helden. die sehr eigensta¨ndig sind. Die Heidin ist in den Grimmschen Marchen an die moralischen Lehren der Zeit gebunden. Von ihr wird verlangt. ein Idealbild in der realen Welt zu sein. Andererseits ist der ma¨nnliche Held arm. faul. arbeitsunfa¨hig und unbeku¨mmert. Er tritt als Abenteurer, Du¨mmling und Retter auf, und hat mit der Hilfe von Zauber oder einem Erlo¨ser Glu¨ck. wenn er nur Mut hat. Er ist nicht eigentlich ein Vorbild. dem man nacheifert. sondern ein Traumbild, das man bewundert. Man mo¨chte so sein wie er und ist sich zugleich bewuβt. dass man nicht so ist und wohl auch niemals so sein wird. und gerade deshalb wu¨nscht man sich so zu sein wie er. Er ist also kein Idealbild fur die reale Welt. sondern ein Wunschbild in der Traumwelt des Ma¨rchens. Der weibliche Held ist zwar sehr bekannt, aber nicht frei von den Forderungen der Wirklichkeit.

공간정보를 이용한 홍수재해지도 예측분석

임희창, 최석근 충북대학교 건설기술연구소 2013 충북대학교 건설기술연구소 논문집 Vol.32 No.1

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Aspergillus oryzae를 이용한 캡슐형 메주의 품질특성

최재훈,권선화,이상원,남상해,최상도,박석규 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3

전통메주의 표면에서 발행하는 야생곰팡이 착생, 유해곰팡이에 대한 mycotoxin 생성 및 메주 표면의 과도한 건조 등을 해결하기 위하여 메주 외층에 Aspergillus oryzae로 만든 쌀 종국(0.3%, w/w)을 혼합시킨 증자 검정콩으로 얇게 코팅한 후, 25℃, 상대습도 80%에서 14일간 발효시킨 캡슐형 메주를 개발하였다. 캡슐형 메주의 표면에서 야생곰팡이의 오염은 발견되지 않았으나, 대조구 메주는 12일 이후에 푸른곰팡이가 많이 관찰되었다. 메주의 수분 함량은 평균 32.7%로서 34.7~29.4%의 범위를 나타내었다. 적정산도는 캡슐형 메주가 대조구 메주보다 높게 나타났으며, 대두 캡슐형 메주와 검정콩 캡슐형 메주는 비슷하게 나타났다. 유리당의 함량은 검정콩 캡슐형 메주가 123.98㎎%로 대조구 메주 15.02㎎%와 대두 캡슐형 메주 59.85㎎%보다 각각 10배, 2.1배, 높게 나타났다. 아미노산성 질소의 함량은 대조구 메주에서 147.00㎎%였으며, 검정콩 캡슐형 메주는 255.50㎎%로서 대두 캡슐형 메주 187.25㎎%보다 약 1.37배 높은 함량을 나타내었다. 총 유기산의 함량은 캡슐형 메주(대두 119.98㎎%, 검정콩 95.94㎎%)가 대조두 메주(26.44㎎%)보다 함량이 높게 나타났으며, 캡슐화에 따라 lactic acid와 malic acid 가 가장 큰 변화를 나타내었다. 색차계 색도는 검정콩 캡슐형 메주가 대두 캡슐형 메주보다 명도값(L)이 크게 나타났으며 지방산 조성은 메주의 종류에 따라 큰 차이를 나타내지 않았다. 총 유리 아미노산의 함량은 검정콩 캡슐형 메주(1039.70㎎%)가 대두 캡슐형 메주 (556.07㎎%)와 대조구 메주(236.45㎎%) 비하여 각각 2.4배, 4.4배 높았다. In order to improve some problems such as contamination of undersirable mold, mycotoxin production and excessive drying on the surface of traditional meju, we developed a capsule type-meju(CM) coated with steamed black bean and Aspergillus oryzae - rice koji(0.3%, w/w) mixture to surface of traditional meju and fermented at 25℃ for 14 days under 80% relative hunmidity. Contamination of undersirable mold on the surface of CM was not detected within 2 weeks and some genus Penicillium molds on control meju without koji were found naturally after 12 days of fermentation. The moisture content of meju was showed to be in the range of 34.7 - 29.4% being 32.7(w/w) of mean value. Titratable acidities in CMs prepared with black bean(BCM) and soybean(SCM) were much higher than that in control meju, and BCM was similar to SCM. Free sugar content in BCM(123.98 ㎎%) was 10 times and 2.1 times higher than that in control meju(15.02 ㎎%) and SCM(59.85㎎%), respectively. Amino type nitrogen content in control meju was 147.00 ㎎% and its content in BCM(255.50㎎%) was 1.37 times higher than that in SCM(187.25 mg%). Total organic acid content in BCM(95.98㎎%) and SCM(119.98㎎%) were much higher than that in control meju(26.44 ㎎%), and then latic and malic acid contents were markedly changed according to capsulation of meju. Lightness value(l) of Hunter color index was much higher in BCM than in SCM. Fatty acid composition of CM was not different as compared to control meju. Total free amino acid content in BCM(1039.70 ㎎%) was 4.4 times and 2.4 times higher than that in control meju(236.45 ㎎%) and SCM(556.07 ㎎%), respectively.

뒤렌마트의 喜劇理論

崔錫姬 대구효성가톨릭대학교 1984 연구논문집 Vol.28 No.1

재삽입을 수행하는 고차원 색인 구조를 위한 효율적인 동시성 제어 알고리즘

최길성,이석희,송석일,유재수,조기형 충북대학교 컴퓨터 정보통신 연구소 1999 컴퓨터정보통신연구 Vol.7 No.1

본 논문에서는 기존의 동시성 제어 기법들을 분석하고 CIR-트리를 위한 효율적인 동시성 제어 알고리즘을 제안한다. 기존에 다차원 색인구조에 대한 동시성 제어 기법으로 제시된 ??-트리는 다른 기법들에 비해 동시성 효율이 우수한 것으로 알려져 있다. 하지만 ??-트리를 CIR-트리에 그대로 적용할 경우 두 가지 문제점이 발생된다. 첫째는, CIR-트리의 성능 향상에 중요한 요소가 되는 재삽입에 대한 동시성 제어를 ??-트리에서 고려하지 않고 있다. 둘째는, ??-트리는 동시성 수준의 한계가 있는 잠금 결합 기법을 사용하고 있다. 본 논문은 두 가지 문제점을 해결할 수 있는 새로운 동시성 제어 알고리즘을 제안하며, 제안된 동시성 제어 알고리즘의 정확성을 증명한다. 또한, 제안한 알고리즘이 기존의 알고리즘에 비해 성능이 우수함을 실험을 통해서 보인다. In this paper we analyze existing concurrency control methods and propose an efficient concurrency control algorithm for CIR-tree. Among the existing concurrency control methods for multidimensional index structures, ??-Tree is one of the most efficient concurrency control algorithm. However, when we apply ??-Tree to the CIR-tree, there are two problems. First ??-Tree does not consider concurrency control for reinsertion operations that are main factor of performance improvement in the CIR-tree. Second since the ??-Tree uses lock-coupling strategy, it limits concurrency of the CIR-tree. The proposed concurrency control algorithm overcomes the two problems. We show the correctness of our proposed currency control algorithm. It is also shown through experiments that our algorithm outperforms the existing algorithms.

프레스 금형의 특징형상 인식에 의한 가공데이타 자동변환

최홍태,반갑수,이석희 한국경영과학회 1994 한국경영과학회 학술대회논문집 Vol.- No.1

This paper presents an automatic conversion of machining data from the orthographic views of press mold by feature recognition rule. The system includes following 6 modules : separation of views, function support, dimension text check and feature processing modules. The characteristic of this system is that with minimum user intervention, it recognizes basic features such as holes, slots, pockets and clamping parts and thus automatically converts CAD drawing details of press mold into machining data using 2D CAD system instead of using an expensive 3D Modeler. The system is developed by using IBM-PC in the environment of AutoCAD R12, AutoLISP and MetaWare High C. Performance of the system is verified as a good interfacing of CAD and CAM when applied to a lot of sample drawing.

양측성 관상동정맥루 1예

최용원,오석규,이재훈,이상재,권경희,최은경,김남호,정진원 圓光大學校 醫科學硏究所 2002 圓光醫科學 Vol.17 No.1

저자들은 호흡곤란, 흉부불쾌감, 심계항진 등을 주소로 내원한 환자에서 경흉부 및 경식도 심초음파 검사상 주폐동맥에서 이완기에 전행하는 지속적인 혈류의 흐름을 관찰하고, 관상동맥 조영술을 통해 좌전하행지 중간부위와 우관상동맥 근위부에서 각각 기시하여 공통경로를 이루면서 주폐동맥으로 유입되는 양측성 관상동정맥루를 보이는 드문 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. A coronary arteriovenous fistula is infrequently encountered vascular communication between a coronary artery and a cardiac chamber, a great artery or the vena cava. It is the most common congenital anomaly that can affect coronary perfusion. Bilateral involvement of coronary fistula constitutes an uncommon subgroup of coronary arteriovenous fistulas. A 69 year-old female patient presented with chest discomfort, palpitation, and dyspnea. In the echocardiography, doppler color flow imaging visualized abnormal flow signals with mosaic appearance in the main pulmonary artery during diastolic phase. Coronary angiography revealed arteriovenous fistula arising from the left anterior descending artery and the right coronary artery. Both coronary arteriovenous fistulas drained into the main pulmonary artery. We report a case of bilateral coronary arteriovenous fistula that was confirmed by echocariography and coronary angiography.

乳房炎 乳汁에서 分離된 原因菌의 抗菌劑 感受性

崔民淳,金鍾冕,趙正坤,蔡孝錫,姜明大,宋熹鍾 全北大學校 附設 畜産開發硏究所 1987 畜産開發硏究報告 Vol.1 No.-

A total of 189 strains (Streptococcus agalactiae and non-Streptococcus agalactiae 110, Staphylococcus aureus 63, and E. coli 16) isolated from bovine mastitie milk samples by "The Connecticut Mastitis Control Program" in dairy herds were examined for drug susceptibility to 8 drugs and analysed the rate of multiple resistant patterns. 1. All of the isolates were resistant to antimicrobial agents such as penicillin (PC), streptomycin (SM), kanamycin(KM), carbenicillin (CA), lincomycin (LM), gentamicin (GM), and tetracycline (TC), singly or multiply. The isolates were more susceptible to CA (84.1%),PC (78.9%), and SM (78.4%) than the the other drugs such as GM (51.8%), KM (48.7%), TC (19.6%) and LM (19.0%) in order. 2. The multiple resistant isolates (96.3%) were more than those of singly resistant isolates (3.7%) and 58 different drug resistant patterns were observed. Among 7 singly resistant isolates, CP was the commonest. While among 182 multiple resistant isolates, CP-KM-LM-TC-GM, CP-LM-TC, CP-LM-TC-GM, PC-CP-SM-LM-TC-GM, CP-KM-LM-TC, and CP-LM patterns were frequently encounted. 3. The strains of streptococcus spp. were more susceptible to CA (90.1%) and SM (82.9%) than the other drugs such as KM (43.2%), GM (38.7%), LM (13.5%), CP (10.8%) and TC (10.8%). Among them CP-KM-LM-TC-CM pattern was frequently encounted. 4. The strains of Sta. aureus were more susceptible to PC (74.6%),CA (69.8%), SM (65.1%) and GM (63.5%) than the other drugs such as KM (46.0%), CP (22.2%), TC (15.9%) and LM (9.5%). Among them CP-LM-TC pattern was commonly encounted. 5. The strains of E. coli were more susceptible to CA (100%) and KM (75.0%) tnan TC (9.5%). But the other drugs such as PC, SM, GM, CP and LM were not. Among them PC-CP-SM-LM-TC-GM pattern was commonly encounted.