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      • KCI등재
      • KCI등재

        전도성 소재가 코팅된 신경도관을 이용한 회돌이 후두신경의 재생

        최정석,김현,안혜영,심봉섭,임재열 대한갑상선학회 2015 International Journal of Thyroidology Vol.8 No.1

        Background and Objectives: Recurrent laryngeal nerve (RLN) damage commonly occurs from a thyroid surgery and causes communication impairment, aspiration and dysphagia. The purpose of this study is to develop a polycaprolactone (PCL) nerve guide conduit (NGC) coated with conductive materials for facilitating regeneration from the RLN defects and to evaluate the usefulness of the PCL NGC coated with conductive materials in a rabbit model. Materials and Methods: The PCL NGCs coated with conductive materials were fabricated for this study. The types of conductive materials were single-walled carbon nanotubes (SWNTs) and poly (3,4-ethylenedioxythiophene): polystyrene sulfonate (PEDOT:PSS) which were coated on the PCL NGCs by layer-by-layer (LBL) assembly techniques. An 8-mm segment of left RLN was resected in 24 New Zealand white rabbits. Three different NGCs (PCL and PCL with two conductive materials) were interposed between both stumps and fixed with suture. For the assessment of functional regeneration, the vocal cord mobility was observed using endoscopic system after RLN stimulation, and the motion change was analyzed. The atrophies of thyroarytenoid muscle and nerve growth were evaluated by Hematoxylin-Eosin (H-E) and toluidine blue (T-B) staining, respectively. Immunohistochemical study using anti-neurofilament, S-100 staining was further performed to evaluate the nerve regeneration. Results: In endoscopic evaluation, the group with conductive PCL NGCs showed an improved tendency of vocal cord mobility compared to that of the other group. Nerve growth was observed with the time for 8 weeks in all groups and immunohistochemical staining revealed the expression of neurofilament and S-100 in regenerated nerve in all groups. The atrophies of thyroarytenoid muscle in the group with conductive PCL NGCs was also shown to be decreased compared to that of the nonconductive PCL NGC group. Conclusion: The study shows that PCL NGC coated with conductive materials appears to be a good alternative option for the repair and regeneration of RNL damages.

      • KCI등재후보

        방사성요오드 치료 후 생긴 타액선염에 대한 타액선내시경술의 유용성

        최정석,임재열,김영모 대한갑상선학회 2012 International Journal of Thyroidology Vol.5 No.1

        Background and Objectives: Ablation of the thyroid remnants using radioiodine (RI) after surgical removal of differentiated thyroid cancer could induce radiation-related salivary gland dysfunction. The purpose of this study is to review our experience with therapeutic sialendoscopy for RI-induced sialadenitis. Materials and Methods: We reviewed medical charts of all patients with RI-induced sialadenitis treated with sialendoscopy retrospectively. The study included 14 patients who underwent sialendoscopy for the treatment of RI-induced sialadenitis after failing conservative management. Results: 14 patients (11 women, 3 men) with a mean age of 43.8 years (range, 26-60) underwent interventional sialendoscopy for the treatment of RI-induced sialadenitis that is unresponsive to conservative management. Symptoms arising from the parotid gland were seen in 12(86%) of patients, whereas symptoms arising from the submandibular gland were seen in 2 (14%). 7 patients (50%) presented symptoms in bilateral parotid or submandibular glands. The mean dose of RI was 203.2 mCi (range, 150-500) received as a single dose. The mean duration from RI ablation therapy to sialendoscopy was 11.1 months (range, 0.5-29). Sialendoscopy was possible in all patients. Ductal stenosis and mucus plugs and debris were the most common types of ductal pathology. Sialendoscopy improved the symptoms in 79% (11/14)of patients, with no serious complications reported in mean follow up of 4 months (range, 1-12). Conclusion:Therapeutic interventional sialendoscopy appears to provide symptom improvement in most patients. Sialendoscopy is effective tool for improving symptoms due to RI-induced sialadenitis in patients who are unresponsive to conservative managements.

      • KCI등재

        한중수교 30주년 한국의 중국 경제경영분야 논문회고 -한중사회과학연구를 중심으로-

        최정석,최준환 한중사회과학학회 2023 한중사회과학연구 Vol.21 No.2

        In commemoration of the 30th anniversary of diplomatic ties between Korea and China, research trends in the field of economic management in China were examined for about 15 years from 2007 to 2022, when Korea-China social science research was selected as a candidate for registration. Over the past 15 years, a total of 213 theses have been published in various fields of social science, such as politics, administration, law, society, and culture, on China, and 401 other papers in the field of economic management have been registered in Korea-China Social Science Research. was found to be particularly specialized in the field of economic management. Specifically, looking at research trends in the field of economic management, macroeconomics 77 (12.5%), management 74 (12.1%), finance 59 (9.6%), business 59 (9.6%), trade 68 64 articles (11.1%), 64 articles in industry (10.4%), and 213 articles in others (34.7%), it was found that research was proceeding evenly except for others. This thesis was written in commemoration of the 30th anniversary of diplomatic ties between Korea and China and the 20th anniversary of the publication of an academic journal on social science research between Korea and China. I think it is meaningful in that it presented the sketch and problems of economic management research. If the difficulties and deficiencies of Chinese economic research are overcome in future Korean-Chinese social science research journals through the basic data of this paper, it is expected that the accumulation of research results in the field of Chinese economic management will grow rapidly in both quantity and quality. 한중수교30주년을 기념하여 한국의 중국 경제경영분야에 대한 연구경향을 한중사회과학학회에서 발간하는 한중사회과학연구 학술지를 중심으로 살펴보았다. 한중사회과학연구는 2003년 창간한 지 4년 만인 2007년 등재후보지로 선정되었고, 이후 3년만인2010년 또다시 등재지로 승격되어 현재까지 13년 간 유지되고 있다. 특히 최근 2021년과 2022년에는 한국연구재단에서 발주하는 학술지 지원 사업에 선정되는 성과를 거두며 한국 지역학 분야의 우수학회지 중 하나로 발전해하고 있는 상황이다. 한중사회과학연구가 등재후보지로 선정된 2007년 이후부터 2022년까지 약 15년 간중국 경제경영분야에 대한 연구경향을 살펴본 결과, 중국에 대한 정치, 행정, 법률, 사회, 문화 등 사회과학 분야의 다방면에서 총 213편의 논문이 등재되었고, 이외 경제경영분야의 논문은 401편으로, 한중사회과학연구에 게재된 논문분야는 특히 경제경영분야가 특화되어 있음을 알 수 있었다. 세부적으로 경제경영분야를 7개 분야로 나누어 연구동향을 살펴보니, 거시경제 77편(12.5%), 경영 74편(12.1%), 금융 59편(9.6%), 기업 59편(9.6%), 무역통상 68편(11.1%), 산업 64편(10.4%), 기타 213편(34.7%)으로, 기타를 제외하고는 고르게 연구가 진행되고있음을 알 수 있었다. 특히 기타분야를 살펴보면, 한중사회과학연구 학술지의 연구범위에 부합하게 중국학에 대한 정치, 행정, 법률, 사회, 문화 등 경제경영분야를 제외한사회과학 분야의 제 학문을 포괄하는 영역에 대해 연구가 광범위하게 이루어지고 있음을 알 수 있었다. 본 논문은 한중수교 30주년을 기념하여 한국의 중국에 대한 경제경영분야 연구가얼마나 진행되고 있는지 한중사회과학연구를 중심으로 연구경향을 살펴본 것으로, 과거 선행연구가 거의 없는 상황에서, 중국에 대한 경제경영연구의 밑그림과 문제점을제시했다는 점에서 의의가 있다고 생각한다. 본 논문의 기초자료를 통해 향후 한중사회과학연구 학술지에서 중국경제 연구의 어려움과 부족함을 극복한다면, 중국 경제경영분야의 연구성과 축적이 양적⋅질적으로 빠르게 성장할 것으로 기대된다.

      • KCI등재

        갑상선에 생긴 원발성 편평세포암에 관한 고찰

        최정석,임재열,주영채,송순욱,김영모 대한이비인후과학회 2012 대한이비인후과학회지 두경부외과학 Vol.55 No.1

        Background and ObjectivesZZSquamous cell carcinoma of thyroid is uncommon and accounts for less than 1% of all primary thyroid malignancies. Clinical features mimic the natural course of anaplastic carcinoma. This study reviewed the clinical course of six cases of primary squamous cell carcinoma of thyroid. Subjects and MethodZZWe diagnosed six cases of primary squamous cell carcinoma of thyroid diagnosed from 1999 to 2006 at the College of Medicine Department of Pathology. Clinical data, treatment modality, and pathologic test results from medical records were retrospectively analyzed. ResultsZZWe found five women and one man (with the mean age of 52.1 years) with squamous cell carcinoma of thyroid. The main presenting features were abruptly enlarging neck swelling and obstructive symptom. Pre-operative needle aspiration biopsy revealed papillary carcinoma in five cases. Only one patient was diagnosed as squamous cell carcinoma through pre-operative needle aspiration biopsy. Three patients had massive adjacent organ invasion, and four patients had lymph node metastasis according to the pathology review. There were no cases of distant metastasis at the time of treatment. All patients received surgery and adjuvant therapy (radiation therapy, chemotherapy, radioiodine therapy). Three patients are still alive with a mean follow up period of 47.3 months (range, 44-49 months). The other three patients died within one year post-operatively. ConclusionZZPrimary squamous cell carcinoma of thyroid should be considered in patients diagnosed with papillary carcinoma and who exhibit aggressive clinical behavior. Complete tumor resection and radiotherapy should be performed if thyroid squamous cell carcinoma is confirmed.

      • KCI등재

        중국 대형철강기업의 부상과 성장전략 연구 -허베이(河北)철강기업을 중심으로-

        최정석,최준환 한중사회과학학회 2015 한중사회과학연구 Vol.13 No.1

        鋼鐵工業作爲基礎原料工業, 在國民經濟中具有居足輕重的地位. 新中國成立60年以來, 中國鋼鐵工業已取得了巨大的成就. 1949年新中國成立初期, 中國鋼産量僅爲15.8億□, 此後, 鋼鐵工業逐步發展和壯大起來;至1996年, 中國鋼鐵産量首次突破億□大關, 位居世界首位, 從此之後, 中國鋼産量壹直穩居世界第壹的寶座. 特別是,由於鋼鐵工業的規模經濟的特征,地區方面的重要性越來越提高了. 最近中國內鋼鐵工業最發達的地區是河北省. 2012年河北省的粗鋼生産量是17000萬□, 這是中國1/4, 河北省經濟的28.9%的比重, 河北省是中國最大的鋼鐵生産基地. 河北省的主要鋼鐵企業是2008年設立的河北鋼鐵公司. 公司的規模是中國最大, 但比寶山鋼鐵公司競爭力方面沒有優勢. 問題的是公司合□效果不大,而且企業管理和R&D水平比較低. 根據河北鋼鐵公司董事長的王義芳提出了, 公司的主要問題是沒有完全構建“市場指向的顧客中心”的經營方式, 因此商品的R&D能力和高級技術人員不足. 以上的背景下, 本論文的構成是如下;第壹章是導論, 第二章考察了中國政府的主要鋼鐵工業政策, 則中國鋼鐵工業的現狀和2005年頒布的鋼鐵工業發展政策, 2009年頒布的中國鋼鐵工業5大振興計劃, 2011年頒布的鋼鐵12·5發展戰略建議, 2013年頒布的鋼鐵工業結構調整7個規制案等, 第三章分析了中國河北鋼鐵公司的增長戰略, 則合□過程和合□模型, SWOT分析, 成長性分析等, 最後導出了結論.

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