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      • KCI등재

        Preparation and photocatalytic activity of a novel BiOCl/g‑C3N4 thin film prepared via spin coating

        Wei‑Qin Cai,De‑Fang Zhang,Feng‑Jun Zhang,Won‑Chun Oh 한국세라믹학회 2020 한국세라믹학회지 Vol.57 No.3

        Novel BiOCl/g-C3N4 thin film photocatalysts were synthesized via a simple two-step spin coating method. The prepared photocatalysts were characterized by X-ray diffraction, scanning electron microscopy, and ultraviolet–visible spectroscopy. The photocatalytic activity of the thin films for the degradation of rhodamine B under visible light (λ ≥ 400 nm) was investigated. The results showed that the BiOCl/g-C3N4 thin film photocatalysts exhibited significantly improved visible light absorption compared to the pure BiOCl thin film. The BiOCl/g-C3N4 film showed a rhodamine B degradation efficiency of 81.0% under visible light, which is 23.8 times higher than that of the pure BiOCl thin film. This excellent photocatalytic activity of the BiOCl/g-C3N4 film can be attributed to its efficient electron–hole separation due to the presence of g-C3N4.

      • KCI등재

        ENVIRONMENTAL DYNAMICS IN AN INTEGRATED WALRASIAN-GENERAL EQUILIBRIUM AND NEOCLASSICAL-GROWTH THEORY

        Wei-Bin Zhang 중앙대학교 경제연구소 2014 Journal of Economic Development Vol.39 No.3

        This study deals with interactions of economic growth and environmental change with heterogeneous households. The analytical framework is built by integrating the three important theories in economics - the Walrasian general equilibrium theory, the neoclassical growth theory, and the neoclassical growth model with endogenous environment. The three theories are integrated by applying Zhang’s approach to household behavior. The economic system consists of one capital goods sector, one consumer goods sector, one environmental sector, and any number (of types) of households. The motion is described by a set of differential equations. For illustration, we simulated the motion of the economic system with three groups. The comparative analyses provide some insights into the complexity of economic growth with environment. For instance, the study by Grossman and Krueger (1995, p. 353) identifies no evidence that “environmental quality deteriorates steadily with economic growth.” Our simulation indicates that although the conclusion made by Crossman and Krueger holds for the national economy, but is invalid for a certain group.

      • KCI등재

        Microstructure and Mechanical Properties of Cold Drawn Ti–Nb–Ta–Zr–O Wires for Orthodontic Applications

        Wei‑dong Zhang,Junye Ren,Bin Liu,Yong Liu,Zhenggang Wu,Jingwen Qiu 대한금속·재료학회 2020 METALS AND MATERIALS International Vol.26 No.7

        Ti–36Nb–2Ta–3Zr–0.35O (TNTZO) alloy is an excellent candidate for biomedical applications. In this study, a new methodcombining cold-swaging and cold-drawing was used to fabricate the TNTZO alloy wires with 0.3 mm diameter for orthodonticapplications. The microstructure and mechanical properties of cold-drawn and annealed TNTZO wires (referred toas TNTZO0.3and TNTZO0.3(HT), respectively) were investigated. The results show that the microstructure of cold drawnTNTZO0.3consists of main-sized elongated grains with 70 nm width. After annealing at 700 °C for 5 min, the microstructureof TNTZO0.3(HT) wires becomes equiaxial with a grain size of ~ 5 μm. The cold drawn TNTZO0.3wires exhibit improvedmechanical properties, higher tensile strength (about 1000 MPa) and similar elastic modulus (69 GPa), compared to annealedTNTZO0.3(HT) wires. Besides, TNTZO0.3has higher creep resistance and lower stress exponent (around 2), compared to Tiwires and TC4 wires with the same diameter. These results prove that TNTZO0.3wires have most of the ideal characteristicsof orthodontic wires.

      • KCI등재

        Methodology of uncertainty analysis prediction based on multi-well data fusion

        Huan Jie Zhang,Kai Wei,Alain P. Tchameni,G. Ben-Kane 한국자원공학회 2018 Geosystem engineering Vol.21 No.3

        During drilling activities, geological parameters of a well to be drilled (target well) can be predicted within a limited interval based on multi-well data fusion which aims at ensuring a drilling safety, enhancement of drilling efficiency, reduction of drilling cost as well as acquiring accurate measurements in respect to Oil and Gas protection layers. This work presents a method of uncertainty analysis prediction of pressures using fusion data (formation pressures) from adjacent multi-well. The Eaton method, effective stress theory, and mathematical confidence interval were the various methods used to establish the formation pressure matrix of the target well. The results revealed that due to the complexity and variability of the formations, data interpretation errors of the geological parameters were inevitable. Therefore, the probability density distribution function was established through stratigraphy, probability statistics, and information diffusion. Moreover, the real value of the wells’ formation pressure (target well) was within the distribution interval of multi-well data fusion. Hence, the developed method cannot only effectively reduce the interval of geological parameter of the target well but also enhance the accuracy of parameters prediction.

      • KCI등재

        Analysis of the Effects of Al on the Ductile-to-Brittle Transition Behavior of Ferritic Heat-Resistant Stainless Steels

        Yingbo Zhang,Dening Zou,Xiaoqiao Wang,Fengshe Xia,Yong Wang,Wei Zhang 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.7

        The effect of Al content on the microstructure and ductile-brittle transition temperature (DBTT) of 18Cr–Al–Si ferritic heatresistantstainless steel have been studied by Charpy impact testing over temperatures ranging from 20 to 90 ℃. Charpy impacttest results show that DBTT increased with increasing Al content. Meanwhile, fracture morphology changed with increasingAl content, where the amount of dimples decreased and cleavage facets increased, indicating increases in the tendency forbrittle fracture. Furthermore, ferrite grain size, volume fraction and size of (Cr, Fe)23C6 carbides increased with increasingAl content, which led to decreasing toughness and increasing DBTT.

      • KCI등재

        Cross-Layer Resource Allocation in Multi-interface Multi-channel Wireless Multi-hop Networks

        Wei Feng,Suili Feng,Yongzhong Zhang3,Xiaowei Xia 한국전자통신연구원 2014 ETRI Journal Vol.36 No.6

        In this paper, an analytical framework is proposed forthe optimization of network performance through jointcongestion control, channel allocation, rate allocation,power control, scheduling, and routing with theconsideration of fairness in multi-channel wireless multihopnetworks. More specifically, the framework modelsthe network by a generalized network utilitymaximization (NUM) problem under an elastic link datarate and power constraints. Using the dual decompositiontechnique, the NUM problem is decomposed into foursubproblems — flow control; next-hop routing; rateallocation and scheduling; power control; and channelallocation — and finally solved by a low-complexitydistributed method. Simulation results show that theproposed distributed algorithm significantly improves thenetwork throughput and energy efficiency compared withprevious algorithms.

      • KCI등재

        A New ent-Kaurane type Diterpenoid Glycoside from Inula japonica Thunb

        Jiang Jiang Qin,Jia Xian Zhu,Wei Dong Zhang1,2,Yan Zhu,Jian Jun Fu,Xiao Hua Liu,Hui Zi Jin 대한약학회 2009 Archives of Pharmacal Research Vol.32 No.10

        A new ent-kaurane type diterpenoid glycoside, 17-O-β-D-glucopyranosyl-16α-ent-kauran-19-oic acid (1), together with 17-hydroxy-16α-ent-kauran-19-oic acid (2), 16α,17-dihydroxyl-ent-kauran-19-oic acid (3), and 16α-hydroxy-17-acetoxy-ent- kauran-19-oic acid (4) were isolated from the aerial parts of Inula japonica Thunb. The structure of 1 was determined mainly by use of 1D and 2D NMR spectroscopic techniques including HSQC, 1H-1H COSY, HMBC, and NOESY. In addition, 4 exhibited significant inhibitory activity on NO production in LPS-stimulated RAW264.7 cells with IC50 value of 14.3 μg/mL.

      • Dynamics Modeling and Simulation Analysis for Wood High-speed Motorized Spindle

        Wei Zhang,Shuangyong Wang,Yang Zhang,Hailong He,Pengfei Zhang 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.1

        In this paper, considering the main factor in the high-speed processing, including the mass of the spindle, the offset of the centroid, bearing span, bearing stiffness and spindle speed , a dynamic model of the spindle-bearing system is established. After carrying out a simulation by Matlab, vibration curve of the spindle-bearing system is obtained, and influence on the vibration characteristics of the spindle bearing system by the centroid offset is analyzed. These works provide the basis for further studies on the vibration mechanism of the high-speed motorized spindle.

      • KCI등재후보

        MiRNA320a Inhibitor-Loaded PLGA-PLL-PEG Nanoparticles Contribute to Bone Regeneration in Trauma-Induced Osteonecrosis Model of the Femoral Head

        Zhang Ying,Li Chuan,Wei Qiushi,Yuan Qiang,He Wei,Zhang Ning,Dong Yiping,Jing Zhenhao,Zhang Leilei,Wang Haibin,Cao Xiangyang 한국조직공학과 재생의학회 2024 조직공학과 재생의학 Vol.21 No.1

        BACKGROUND: This study aimed to explore the effect of a nanomaterial-based miR-320a inhibitor sustained release system in trauma-induced osteonecrosis of the femoral head (TIONFH). METHODS: The miR-320a inhibitor-loaded polyethylene glycol (PEG)- Poly(lactic-co-glycolic acid) (PLGA)- Poly-L-lysine (PLL) nanoparticles were constructed using the double emulsion method. The TIONFH rabbit model was established to observe the effects of miR-320a inhibitor nanoparticles in vivo. Hematoxylin–eosin staining and microcomputed tomography scanning were used for bone morphology analysis. Bone marrow mesenchymal stem cells (BMSCs), derived from TIONFH rabbits, were used for in vitro experiments. Cell viability was determined using the MTT assay. RESULTS: High expression of miR-320a inhibited the osteogenic differentiation capacity of BMSCs in vitro by inhibiting the expression of the osteoblastic differentiation markers ALP and RUNX2. MiR-320a inhibitor-loaded PEG-PLGA-PLL nanoparticles were constructed with a mean loading efficiency of 1.414 ± 0.160%, and a mean encapsulation efficiency of 93.45 ± 1.24%, which released 50% of the loaded miR-320a inhibitor at day 12 and 80% on day 18. Then, inhibitor release entered the plateau. After treatment with the miR-320a inhibitor nanoparticle, the empty lacunae were decreased in the femoral head tissue of TIONFH rabbits, and the osteoblast surface/bone surface (Ob.S/BS), osteoblast number/bone perimeter (Ob.N/B.Pm), bone volume fraction, and bone mineral density increased. Additionally, the expression of osteogenic markers RUNX2 and ALP was significantly elevated in the TIONFH rabbit model. CONCLUSION: The miR-320a inhibitor-loaded PEG-PLGA-PLL nanoparticle sustained drug release system significantly contributed to bone regeneration in the TIONFH rabbit model, which might be a promising strategy for the treatment of TIONFH. BACKGROUND: This study aimed to explore the effect of a nanomaterial-based miR-320a inhibitor sustained release system in trauma-induced osteonecrosis of the femoral head (TIONFH). METHODS: The miR-320a inhibitor-loaded polyethylene glycol (PEG)- Poly(lactic-co-glycolic acid) (PLGA)- Poly-L-lysine (PLL) nanoparticles were constructed using the double emulsion method. The TIONFH rabbit model was established to observe the effects of miR-320a inhibitor nanoparticles in vivo. Hematoxylin–eosin staining and microcomputed tomography scanning were used for bone morphology analysis. Bone marrow mesenchymal stem cells (BMSCs), derived from TIONFH rabbits, were used for in vitro experiments. Cell viability was determined using the MTT assay. RESULTS: High expression of miR-320a inhibited the osteogenic differentiation capacity of BMSCs in vitro by inhibiting the expression of the osteoblastic differentiation markers ALP and RUNX2. MiR-320a inhibitor-loaded PEG-PLGA-PLL nanoparticles were constructed with a mean loading efficiency of 1.414 ± 0.160%, and a mean encapsulation efficiency of 93.45 ± 1.24%, which released 50% of the loaded miR-320a inhibitor at day 12 and 80% on day 18. Then, inhibitor release entered the plateau. After treatment with the miR-320a inhibitor nanoparticle, the empty lacunae were decreased in the femoral head tissue of TIONFH rabbits, and the osteoblast surface/bone surface (Ob.S/BS), osteoblast number/bone perimeter (Ob.N/B.Pm), bone volume fraction, and bone mineral density increased. Additionally, the expression of osteogenic markers RUNX2 and ALP was significantly elevated in the TIONFH rabbit model. CONCLUSION: The miR-320a inhibitor-loaded PEG-PLGA-PLL nanoparticle sustained drug release system significantly contributed to bone regeneration in the TIONFH rabbit model, which might be a promising strategy for the treatment of TIONFH.

      • KCI등재

        piRNA-1742 promotes renal cell carcinoma malignancy by regulating USP8 stability through binding to hnRNPU and thereby inhibiting MUC12 ubiquitination

        Zhang Wentao,Zheng Zongtai,Wang Keyi,Mao Weipu,Li Xue,Wang Guangchun,Zhang Yuanyuan,Huang Jianhua,Zhang Ning,Wu Pengfei,Liu Ji,Zhang Haimin,Che Jianping,Peng Bo,Zheng Junhua,Li Wei,Yao Xudong 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        Accumulating studies have confirmed that PIWI-interacting RNAs (piRNAs) are considered epigenetic effectors in cancer. We performed piRNA microarray expression analysis on renal cell carcinoma (RCC) tumor tissues and paired normal tissues and performed a series of in vivo and in vitro experiments to explore piRNAs associated with RCC progression and investigate their functional mechanisms. We found that piR-1742 was highly expressed in RCC tumors and that patients with high piR-1742 expression had a poor prognosis. Inhibition of piR-1742 significantly reduced tumor growth in RCC xenograft and organoid models. Mechanistically, piRNA-1742 regulates the stability of USP8 mRNA by binding directly to hnRNPU, which acts as a deubiquitinating enzyme that inhibits the ubiquitination of MUC12 and promotes the development of malignant RCC. Subsequently, nanotherapeutic systems loaded with piRNA-1742 inhibitors were found to effectively inhibit the metastasis and growth of RCC in vivo. Therefore, this study highlights the functional importance of piRNA-related ubiquitination in RCC and demonstrates the development of a related nanotherapeutic system, possibly contributing to the development of therapeutic approaches for RCC.

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